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1421
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
Published 2017“…In addition, many compounds demonstrated activity against other pathogens, showing hits in assays with 16 protozoa, 7 helminths, 9 bacterial and mycobacterial species, the dengue fever mosquito vector, and the NCI60 human cancer cell line panel of 60 human tumor cell lines. …”
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Article -
1422
COP27 Climate Change Conference: Urgent Action Needed for Africa and the World
Published 2022-11-01“…Africa has suffered disproportionately although it has done little to cause the crisis The climate crisis has had an impact on the environmental and social determinants of health across Africa, leading to devastating health effects.3 Impacts on health can result directly from environmental shocks and indirectly through socially mediated effects.4 Climate change-related risks in Africa include flooding, drought, heatwaves, reduced food production, and reduced labour productivity.5 Droughts in sub-Saharan Africa have tripled between 1970-79 and 2010-2019.6 In 2018, devastating cyclones impacted 2.2 million people in Malawi, Mozambique and Zimbabwe.6 In west and central Africa, severe flooding resulted in mortality and forced migration from loss of shelter, cultivated land, and livestock.7 Changes in vector ecology brought about by floods and damage to environmental hygiene has led to increases in diseases across sub-Saharan Africa, with rises in malaria, dengue fever, Lassa fever, Rift Valley fever, Lyme disease, Ebola virus, West Nile virus and other infections.8,9 Rising sea levels reduce water quality, leading to water-borne diseases, including diarrhoeal diseases, a leading cause of mortality in Africa.8 Extreme weather damages water and food supply, increasing food insecurity and malnutrition, which causes 1.7 million deaths annually in Africa.10 According to the Food and Agriculture Organization of the United Nations, malnutrition has increased by almost 50% since 2012, owing to the central role agriculture plays in African economies.11 Environmental shocks and their knock-on effects also cause severe harm to mental health.12 In all, it is estimated that the climate crisis has destroyed a fifth of the gross domestic product (GDP) of the countries most vulnerable to climate shocks.13 The damage to Africa should be of supreme concern to all nations. …”
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1423
Biomedical research in france and brazil: an analysis of significant differences and ethical issues
Published 2016-06-01“…Those data highlight the problem of neglected or “orphan” diseases for pharmaceutical companies that have a local impact on mortality or economy, such as dengue fever or Chagas disease(5). Economy Brazil has had a 4% continuing economic growth for the last ten years. …”
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1424
COP27 CLIMATE CHANGE CONFERENCE: URGENT ACTION NEEDED FOR AFRICA AND THE WORLD
Published 2022-12-01“…Changes in vector ecology brought about by floods and damage to environmental hygiene has led to increases in diseases across sub-Saharan Africa, with rises in malaria, dengue fever, Lassa fever, Rift Valley fever, Lyme disease, Ebola virus, West Nile virus and other infections (8, 9). …”
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1425
Serological and clinical diagnosis of dengue virus infection - A review of current knowledge
Published 2006“…Dengue fever, dengue haemorrhagic fever and dengue shock syndrome are tropical diseases that cause significant disease burden. …”
Journal article -
1426
Dengue: a continuing global threat.
Published 2010“…Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases. …”
Journal article -
1427
Commercial dengue rapid diagnostic tests for point-of-care application: recent evaluations and future needs?
Published 2012“…Dengue fever, dengue haemorrhagic fever, and dengue shock syndrome (DF/DHF/DSS) are tropical diseases that cause significant humanitarian and economic hardship. …”
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1428
PICTUREE—Aedes: A Web Application for Dengue Data Visualization and Case Prediction
Published 2023-05-01“…Dengue fever remains a significant public health concern in many tropical and subtropical countries, and there is still a need for a system that can effectively combine global risk assessment with timely incidence forecasting. …”
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1429
Results of Immunological Screening for Natural-Focal and «Exotic» Infectious Diseases among Certain Population Groups of the Khabarovsk Territory, the Amur Region and the Jewish Au...
Published 2014-03-01“…The findings have revealed the presence of immuno-competent population in the three regions of the Far Eastern Federal district in reference to the agents of natural-focal infectious diseases: tularemia, leptospirosis, yersinioses, hemorrhagic fever with renal syndrome, human granulocytic anaplasmosis, tick-borne borrelioses, tick-borne viral encephalitis, Californian encephalitis serogroup, Sindbis, West Nile and Dengue fevers. Circulation of Batai and Crimean-Congo hemorrhagic fever viruses has not been revealed based on serological assays.…”
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1430
Molecular Changes in Dengue Envelope Protein Domain III upon Interaction with Glycosaminoglycans
Published 2020-11-01“…Dengue fever is a rapidly emerging vector-borne viral disease with a growing global burden of approximately 390 million new infections per annum. …”
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1431
Enhanced Immunogenicity of Inactivated Dengue Vaccines by Novel Polysaccharide-Based Adjuvants in Mice
Published 2022-05-01“…Dengue fever, caused by any of four dengue viruses (DENV1-4), is a major global burden. …”
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1432
The interplay of vaccination and vector control on small dengue networks
Published 2016“…Dengue fever is a major public health issue a↵ecting billions of people in over 100 countries across the globe. …”
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1433
Geospatial analysis of urban land use pattern analysis for hemorrhagic fever risk ' a review
Published 2016“…The study found that most of the available literatures dwell more on the impact of urban land use on malaria and dengue fevers; however, studies are yet to be found discussing the implications of urban land use on the risk of Ebola, Lassa and other non-mosquito borne VHFs. …”
Conference or Workshop Item -
1434
Skilful probabilistic medium‐range precipitation and temperature forecasts over Vietnam for the development of a future dengue early warning system
Published 2024“…Dengue fever is a source of substantial health burden in Vietnam. …”
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1435
The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations.
Published 2011“…Dengue fever is the most important mosquito-borne viral disease of humans with more than 50 million cases estimated annually in more than 100 countries. …”
Journal article