Increasing use of systems science in cardiovascular disease prevention to understand how to address geographic health disparities in communities with a disproportionate burden of r... by Kyla L. Bauer, Krista A. Haapanen, Nathaniel Demeke, Meredith P. Fort, Kamal H. Henderson

“…We provide a case study of systems science application to address geographic CVD health disparities at the community level – informing the science of CVD health disparities research.MethodsWe conducted a two-phased, multi-methods needs assessment in the Denver, Colorado area. Phase I consisted of a social network analysis to map a two-mode network of existing CVD prevention interventions and their implementing organizations. …”
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Purification, characterization, and cloning of a novel pro-inflammatory secreted protein from Staphylococcus aureus by Patrick M. Schlievert, Jacob D. Nelson, Samuel H. Kilgore, Lilliana Radoshevich, Aloysius J. Klingelhutz, Donald Y. M. Leung

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Evaluation of a minimal array of Treponema pallidum antigens as biomarkers for syphilis diagnosis, infection staging, and response to treatment by Austin M. Haynes, Kelika A. Konda, Emily Romeis, Janet Siebert, Silver K. Vargas, Michael Reyes Diaz, Amber Phan, Carlos F. Caceres, Lorenzo Giacani, Jeffrey D. Klausner

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Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease by Choate R, Holm KE, Sandhaus RA, Mannino DM, Strange C

“…Radmila Choate,1 Kristen E Holm,2,3 Robert A Sandhaus,2,3 David M Mannino,4 Charlie Strange3,5 1University of Kentucky College of Public Health, Lexington, Kentucky, USA; 2Department of Medicine, National Jewish Health, Denver, Colorado, USA; 3Alphanet, Inc., Coral Gables, Florida, USA; 4University of Kentucky College of Medicine, Lexington, Kentucky, USA; 5Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, South Carolina, USACorrespondence: Radmila Choate, University of Kentucky College of Public Health, Lexington, Kentucky, USA, Tel +1 859-218-2237, Email Radmila.choate@uky.eduBackground: Health-related quality of life (HRQoL) assessments such as St. …”
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Impact of native-plants policy scenarios on premature mortality in Denver: A quantitative health impact assessment by Michael D. Garber, Michael Guidi, Jennifer Bousselot, Tarik Benmarhnia, Daniel Dean, David Rojas-Rueda

“…Aim: We aim to estimate premature deaths that would be prevented by the implementation of native-plants policy scenarios in the City of Denver, Colorado, USA. Methods: After conducting interviews with local expert stakeholders, we designed four native-plants policy scenarios: (1) greening 30% of all city census-block groups to the greenness level of native plants, (2) adding 200-foot native-plants buffers around riparian areas, (3) constructing large water retention ponds landscaped with native plants, and (4) greening parking lots. …”
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Clinical Benefit of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis for Patients With and Without a Vasculitic Phenotype by Benjamin Terrier, David R.W. Jayne, Bernhard Hellmich, Jane H. Bentley, Jonathan Steinfeld, Steven W. Yancey, Namhee Kwon, Praveen Akuthota, Paneez Khoury, Lee Baylis, Michael E. Wechsler, the EGPA mepolizumab study team

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Reduction in urban water use leads to less wastewater and fewer emissions:analysis of three representative U.S. cities by Aysegul Petek Gursel, Camille Chaudron, Ioanna Kavvada, Arpad Horvath

“…Tucson (Arizona), Denver (Colorado), and Washington, DC were chosen for their distinct locations, climatic conditions, raw water sources, wastewater treatment technologies, and electric power mixes. …”
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24780 Investigating the role of mycobacterial lipid antigens and CD1-restricted T cells in host-protective tuberculosis immunity using a guinea pig model by Macallister Harris, James Dilisio, Hadley Gary, Edward Chan, D. Branch Moody, Brendan Podell

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Insulin‐like growth factor binding Protein‐4: A novel indicator of pulmonary arterial hypertension severity and survival by Guillermo Torres, Jun Yang, Megan Griffiths, Stephanie Brandal, Rachel Damico, Dhananjay Vaidya, Catherine E. Simpson, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Allen D. Everett

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4D‐Flow MRI intracardiac flow analysis considering different subtypes of pulmonary hypertension by Michael T. Cain, Michal Schäfer, Lexie K. Ross, David D. Ivy, Max B. Mitchell, Brett E. Fenster, Todd M. Bull, Alex J. Barker, Daniel Vargas, Jordan R. H. Hoffman

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Safety of endoscopic pancreatic necrosectomy compared with percutaneous and surgical necrosectomy: a nationwide inpatient study by Daryl Ramai, Dan M. McEntire, Kameron Tavakolian, Joseph Heaton, Saurabh Chandan, Banreet Dhindsa, Amaninder Dhaliwal, Marcello Maida, Andrea Anderloni, Antonio Facciorusso, Douglas G. Adler

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Prevalence of sensitization to molecular food allergens in Europe: A systematic review by Daniil Lisik, Athina Ioannidou, Giulia Spolidoro, Mohamed Ali, Sungkutu Nyassi, Yohanes Amera, Graciela Rovner, Ekaterina Khaleva, Carina Venter, Ronald vanRee, Margitta Worm, Berber Vlieg‐Boerstra, Aziz Sheikh, Antonella Muraro, Graham Roberts, Bright I. Nwaru

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Try, try again: Lessons learned from success and failure in participatory modeling by Eleanor J. Sterling, Moira Zellner, Karen E. Jenni, Kirsten Leong, Pierre D. Glynn, Todd K. BenDor, Pierre Bommel, Klaus Hubacek, Antonie J. Jetter, Rebecca Jordan, Laura Schmitt Olabisi, Michael Paolisso, Steven Gray

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Evaluation of potential biomarkers for lenvatinib plus pembrolizumab among patients with advanced endometrial cancer: results from Study 111/KEYNOTE-146 by Razvan Cristescu, Andrey Loboda, Robert Orlowski, Vicky Makker, Matthew H Taylor, Carol Aghajanian, Petar Jelinic, Lea Dutta, Allen L Cohn, Marcia S Brose, Christopher Di Simone, Zhu Alexander Cao, Leah Suttner, Junji Matsui, Corina E Dutcus, Yukinori Minoshima, Mark J Messing

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Psychometric evaluation of the United States-adapted perceived perioperative competence scale-revised: A national survey by Shannon Maio, James X. Stobinski, Brigid M. Gillespie

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Inhibition of Toxic Shock Syndrome-Associated Staphylococcus aureus by Probiotic Lactobacilli by Patrick M. Schlievert, Adriana V. Gaitán, Samuel H. Kilgore, Amy L. Roe, Johanna Maukonen, Liisa Lehtoranta, Donald Y. M. Leung, Daniel S. Marsman

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Reproducibility of the Ribosomal RNA Synthesis Ratio in Sputum and Association with Markers of Mycobacterium tuberculosis Burden by Emmanuel Musisi, Christian Dide-Agossou, Reem Al Mubarak, Karen Rossmassler, Abdul Wahab Ssesolo, Sylvia Kaswabuli, Patrick Byanyima, Ingvar Sanyu, Josephine Zawedde, William Worodria, Martin I. Voskuil, Rada M. Savic, Payam Nahid, J. Lucian Davis, Laurence Huang, Camille M. Moore, Nicholas D. Walter

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Nephrologists’ perspectives on the impact of COVID-19 on caring for patients undergoing dialysis in Latin America: a qualitative study by Armando Teixeira-Pinto, Germaine Wong, Jonathan Craig, Laura Sola, Alejandra Hernández, Lilia Cervantes, Magdalena Madero, Allison Jauré, Andrea Matus Gonzalez, Eduardo Lorca, Sebastian Cabrera, Carlos Zúñiga-SM, Luis Michea, Alejandro Ferreiro Fuentes

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Remission of lupus nephritis: the trajectory of histological response in successfully treated patients by Brad Rovin, Bethany Wolf, Haikady N Nagaraja, Ana Malvar, Jordi Navarro, Valeria Alberton, Bruno Lococo, Joaquín Martinez, Maria Lourenco, Lucrecia Burna, Celeste Besso, Aastha Khatiwada

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Optimization of a Do-It-Yourself Air Cleaner Design to Reduce Residential Air Pollution Exposure for a Community Experiencing Environmental Injustices by Sumit Sankhyan, Nicholas Clements, Allison Heckman, Aniya K. Hollo, Dulce Gonzalez-Beltran, Jonathan Aumann, Cora Morency, Luke Leiden, Shelly L. Miller

“…In this study, we developed nine air cleaner prototypes, altering filter depth and the number and type of filters, and compared their PM_2.5 removal effectiveness and maintenance-related parameters prior to deployment in North Denver, Colorado homes. Prototypes containing multiple high efficiency particulate air filters with a minimum reporting value of 13 (MERV13) had higher clean air delivery rates (CADR, >300 m³ h⁻¹) compared to prototypes using a single filter (100–200 m³ h⁻¹), but single-filter designs had comparable values of CADR normalized by initial and annual operating costs. …”
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