Drug deposition in coronary arteries with overlapping drug-eluting stents by Olgac, Ufuk, Poulikakos, Dimos, Kurtcuoglu, Vartan, Rikhtegar Nezami, Farhad, Edelman, Elazer R

“…Drug-eluting stents are accepted as mainstream endovascular therapy, yet concerns for their safety may be under-appreciated. …”
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Numerical modeling of local pharmacokinetics associated with drug-eluting stent by Jahid Ferdous

“…To restore distal blood supply and overcome restenosis presented by bare-metal stents, drug-eluting stent (DES) implantation is widely used. However, the long-term efficacy of this mode of treatment is not well-established. …”
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Novel drug-eluting stent to reduce fibrosis-induced ureteral stricture by Fong, Timothy Ren Zhong

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Modeling and Analysis of Drug-Eluting Stents With Biodegradable PLGA Coating: Consequences on Intravascular Drug Delivery by Zhu, Xiaoxiang, Braatz, Richard D

“…Increasing interests have been raised toward the potential applications of biodegradable poly(lactic-co-glycolic acid) (PLGA) coatings for drug-eluting stents in order to improve the drug delivery and reduce adverse outcomes in stented arteries in patients. …”
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Fracture in drug‐eluting stents increases focal intimal hyperplasia in the atherosclerosed rabbit iliac artery by Conway, Claire, Edelman, Elazer R

“…Objectives: Drug-eluting stent (DES) strut fracture (SF) is associated with higher incidence of In-stent restenosis (ISR)—return of blockage in a diseased artery post stenting—than seen with bare metal stents (BMS). …”
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The delivery of nitric oxide through liposomes as next generation drug eluting stents and vascular interventions by Tan, Wei Jie

“…Such means of fabrication would hopefully encourage others to pursue the use of NO for future drug eluting stents.…”
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A bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture recurrence by Lim, Wei Shan

“…It is hypothesized that a bilayer swellable drug-eluting stent (BSDES) that can co-apt with the urothelium for the localized and sustained delivery of drugs into the diseased section can reduce or eliminate stricture recurrence. …”
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Mathematical modeling and simulation of intravascular drug delivery from drug-eluting stents with biodegradable PLGA coating by Zhu, Xiaoxiang, Ph. D. Massachusetts Institute of Technology

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Characterization and evaluation of a bilayer swellable drug-eluting stent for the treatment of fibrosis-induced ureteral stricture by Er, Pei Shan

“…The bilayer swellable drug eluting stent is fabricated by first spraycoating an antiproliferative drug, mitomycin C (MMC) encapsulated in a hydrophobic polymer, poly-L-lactide-co-caprolactone (PLC) onto the stent, followed by surface plasma treatment before coating a hydrogel, polyethylene glycol diacrylate (PEGDA) onto the polymer, via photo-crosslinking. …”
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Comparison of overexpansion capabilities and thrombogenicity at the side branch ostia after implantation of four different drug eluting stents by Gasior, Pawel, Lu, Shengjie, Ng, Jaryl Chen Koon, Toong, Daniel Wee Yee, Wong, Philip En Hou, Foin, Nicolas, Kedhi, Elvin, Wojakowski, Wojciech, Ang, Hui Ying

“…This study aimed to evaluate the overexpansion capabilities and thrombogenicity at the SB ostia after implantation of four latest generation drug-eluting stents (DES) in an in-vitro bifurcation model. …”
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Modelling intravascular delivery from drug-eluting stents with biodurable coating: investigation of anisotropic vascular drug diffusivity and arterial drug distribution by Zhu, Xiaoxiang, Pack, Daniel W., Braatz, Richard D.

“…In-stent restenosis occurs in coronary arteries after implantation of drug-eluting stents with non-uniform restenosis thickness distribution in the artery cross section. …”
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Atherosclerotic plaque behind the stent changes after bare-metal and drug-eluting stent implantation in humans: Implications for late stent failure? by Takahashi, Saeko, Tsuda, Masaya, Shishido, Koki, Mizuno, Shingo, Coskun, Ahmet U., Saito, Shigeru, Feldman, Charles L., Stone, Peter H., Andreou, Ioannis, Antoniadis, Antonios, Papafaklis, Michail, Edelman, Elazer R

“…We evaluated the serial changes in PBS following bare-metal (BMS) compared to first-generation drug-eluting stent (DES) implantation and the impact of these changes on in-stent neointimal hyperplasia (NIH). …”
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A bilayer swellable drug-eluting ureteric stent : localized drug delivery to treat urothelial diseases by Lim, Wei Shan, Chen, Kenneth, Chong, Tsung Wen, Xiong, Gordon Minru, Birch, William R., Pan, Jisheng, Lee, Bae Hoon, Er, Pei Shan, Salvekar, Abhijit Vijay, Venkatraman, Subbu S., Huang, Yingying

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Impact of flow pulsatility on arterial drug distribution in stent-based therapy by O’Brien, Caroline C., Kolachalama, Vijaya Bhasker, Barber, Tracie J., Simmons, Anne, Edelman, Elazer R.

“…Drug-eluting stents reside in a dynamic fluid environment where the extent to which drugs are distributed within the arterial wall is critically modulated by the blood flowing through the arterial lumen. …”
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Comparing long-term antiplatelet strategies to prevent morbidity and mortality in patients with drug-eluting coronary stents by Evans, J. Stewart (James Stewart)

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Pathology of Endovascular Stents by Keating, John H., Nakamura, Kenta, Edelman, Elazer R

“…Keywords: Coronary artery disease; Pathology; Bare metal stent; Drug-eluting stent; In-stent restenosis; In-stent thrombosis; Atherosclerosis; Neoatherosclerosis…”
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In vitro peptide release from e-polycaprolactone and blends of e-polycaprolactone by Adhi Kurnianto

“…Recent invention of drug-eluting stent (DES) has been successful to prevent ISR but signify a long term thrombosis effect. …”
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Stent elution rate determines drug deposition and receptor-mediated effects by Tzafriri, Abraham R., Groothuis, Adam, Price, G. Sylvester, Edelman, Elazer R.

“…Drug eluting stent designs abound and yet the dependence of efficacy on drug dose and elution duration remains unclear. …”
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Evaluation of tissue adhesives for drug eluting balloon using the rotating cylinder by Lim, Cynthia Yun Yun.

“…A stent is also inserted to keep the diseased artery remain open. However, Drug Eluting Stent (DES) is still not a good solution to atherosclerosis as it will cause the onset of late stent restenosis. …”
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Evaluation of pressure sensitive adhesives for drug eluting balloon by Wang, Dione Qian Ying

“…A stent helps to keep the artery remain open. Although drug eluting stents and drug eluting balloons have been designed, drug eluting stent is not a good solution as restenosis will cause the diseased coronary artery to close after a few years. …”
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