4184 Implementation of an Opt-Out recruitment policy at Duke University School of Medicine by Michelle Mack, Jamie Roberts, Dalia Mack, Steven Shipes, Stephanie A. Freel, Marissa Stroo, Roy McDonald, Denise Snyder

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115 The Clinical Research Internship Portal (CRISP): Creating a mechanism for the onboarding and placement of clinical research interns in the Duke University School of Medicine by Amanda McMillan, Denise Snyder, Holly Hough, Taryn Cavanaugh Faulk, Susan Budinger, Stephanie Freel

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The Project Baseline Health Study: a step towards a broader mission to map human health by Kristine Arges, Themistocles Assimes, Vikram Bajaj, Suresh Balu, Mustafa R. Bashir, Laura Beskow, Rosalia Blanco, Robert Califf, Paul Campbell, Larry Carin, Victoria Christian, Scott Cousins, Millie Das, Marie Dockery, Pamela S. Douglas, Ashley Dunham, Julie Eckstrand, Dominik Fleischmann, Emily Ford, Elizabeth Fraulo, John French, Sanjiv S. Gambhir, Geoffrey S. Ginsburg, Robert C. Green, Francois Haddad, Adrian Hernandez, John Hernandez, Erich S. Huang, Glenn Jaffe, Daniel King, Lynne H. Koweek, Curtis Langlotz, Yaping J. Liao, Kenneth W. Mahaffey, Kelly Marcom, William J. Marks, David Maron, Reid McCabe, Shannon McCall, Rebecca McCue, Jessica Mega, David Miller, Lawrence H. Muhlbaier, Rajan Munshi, L. Kristin Newby, Ezra Pak-Harvey, Bray Patrick-Lake, Michael Pencina, Eric D. Peterson, Fatima Rodriguez, Scarlet Shore, Svati Shah, Steven Shipes, George Sledge, Susie Spielman, Ryan Spitler, Terry Schaack, Geeta Swamy, Martin J. Willemink, Charlene A. Wong

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Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations by Wilton B. Williams, Jinsong Zhang, Chuancang Jiang, Nathan I. Nicely, Daniela Fera, Kan Luo, M. Anthony Moody, Hua-Xin Liao, S. Munir Alam, Thomas B. Kepler, Akshaya Ramesh, Kevin Wiehe, James A. Holland, Todd Bradley, Nathan Vandergrift, Kevin O. Saunders, Robert Parks, Andrew Foulger, Shi-Mao Xia, Mattia Bonsignori, David C. Montefiori, Mark Louder, Amanda Eaton, Sampa Santra, Richard Scearce, Laura Sutherland, Amanda Newman, Hilary Bouton-Verville, Cindy Bowman, Howard Bomze, Feng Gao, Dawn J. Marshall, John F. Whitesides, Xiaoyan Nie, Garnett Kelsoe, Steven G. Reed, Christopher B. Fox, Kim Clary, Marguerite Koutsoukos, David Franco, John R. Mascola, Stephen C. Harrison, Barton F. Haynes, Laurent Verkoczy

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Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates by Kevin O. Saunders, Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R. Ryan Meyerhoff, Robert Parks, William E. Walkowicz, Baptiste Aussedat, Nelson R. Wu, Fangping Cai, Yusuf Vohra, Peter K. Park, Amanda Eaton, Eden P. Go, Laura L. Sutherland, Richard M. Scearce, Dan H. Barouch, Ruijun Zhang, Tarra Von Holle, R. Glenn Overman, Kara Anasti, Rogier W. Sanders, M. Anthony Moody, Thomas B. Kepler, Bette Korber, Heather Desaire, Sampa Santra, Norman L. Letvin, Gary J. Nabel, David C. Montefiori, Georgia D. Tomaras, Hua-Xin Liao, S. Munir Alam, Samuel J. Danishefsky, Barton F. Haynes

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Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies by Rory Henderson, Brian E. Watts, Hieu N. Ergin, Kara Anasti, Robert Parks, Shi-Mao Xia, Ashley Trama, Hua-Xin Liao, Kevin O. Saunders, Mattia Bonsignori, Kevin Wiehe, Barton F. Haynes, S. Munir Alam

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Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques by Sommer Holmes, Hui Li, Xiaoying Shen, Mitchell Martin, Ryan Tuck, Yue Chen, Elena E. Giorgi, Hélène Fradin Kirshner, Madison Berry, Elizabeth Van Italie, Sravani Venkatayogi, Joshua S. Martin Beem, Robert J. Edwards, Katayoun Mansouri, Ajay Singh, Cindy Kuykendall, Thaddeus Gurley, M. Anthony Moody, Nicole DeNayer, Todd Demarco, Thomas N. Denny, Yunfei Wang, Tyler D. Evangelous, John T. Clinton, Bhavna Hora, Kshitij Wagh, Michael S. Seaman, Kevin O. Saunders, Nicholas Solomotis, Johnathan Misamore, Mark G. Lewis, Kevin Wiehe, David C. Montefiori, George M. Shaw, Wilton B. Williams

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Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus by Ruijun Zhang, David R. Martinez, Quang N. Nguyen, Justin Pollara, Trina Arifin, Christina Stolarchuk, Andrew Foulger, Josh D. Amos, Robert Parks, Jonathon E. Himes, Minyue Wang, Regina W. Edwards, Ashley M. Trama, Nathan Vandergrift, Lisa Colvin, Ken Dewar, Nikoleta Juretic, Jessica Wasserscheid, Guido Ferrari, Hua-Xin Liao, Sallie R. Permar

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Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies by Bhavna Hora, Hui Li, Xiaoying Shen, Mitchell Martin, Yue Chen, Madison Berry, Tyler Evangelous, Andrew N. Macintyre, Aria Arus-Altuz, Shuyi Wang, Ajay Singh, Chengyan Zhao, Nicole De Naeyer, Todd DeMarco, Cindy Kuykendall, Thaddeus Gurley, Kevin O. Saunders, Thomas Denny, M. Anthony Moody, John Misamore, Mark G. Lewis, Kevin Wiehe, Derek W. Cain, David C. Montefiori, George M. Shaw, Wilton B. Williams

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Correction: You & me: test and treat study protocol for promoting COVID-19 test and treatment access to underserved populations by Emily M. D’Agostino, Lauren M. Rosenberg, Alan Richmond, Allyn Damman, Camille Brown‑Lowery, Princess Abbot‑Grimes, Saira Siddiqui, Tigidankay Fadika, Mark Ward, Mia Cooper, Sonya Sutton, Lindsay Kenton, Bob Spaziano, Janet Kasper, Nicole Barnes, Christoph Hornik

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Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity by Dapeng Li, Simon Brackenridge, Lucy C. Walters, Olivia Swanson, Karl Harlos, Daniel Rozbesky, Derek W. Cain, Kevin Wiehe, Richard M. Scearce, Maggie Barr, Zekun Mu, Robert Parks, Max Quastel, Robert J. Edwards, Yunfei Wang, Wes Rountree, Kevin O. Saunders, Guido Ferrari, Persephone Borrow, E. Yvonne Jones, S. Munir Alam, Mihai L. Azoitei, Geraldine M. Gillespie, Andrew J. McMichael, Barton F. Haynes

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Immune checkpoint modulation enhances HIV-1 antibody induction by Todd Bradley, Masayuki Kuraoka, Chen-Hao Yeh, Ming Tian, Huan Chen, Derek W. Cain, Xuejun Chen, Cheng Cheng, Ali H. Ellebedy, Robert Parks, Maggie Barr, Laura L. Sutherland, Richard M. Scearce, Cindy M. Bowman, Hilary Bouton-Verville, Sampa Santra, Kevin Wiehe, Mark G. Lewis, Ane Ogbe, Persephone Borrow, David Montefiori, Mattia Bonsignori, M. Anthony Moody, Laurent Verkoczy, Kevin O. Saunders, Rafi Ahmed, John R. Mascola, Garnett Kelsoe, Frederick W. Alt, Barton F. Haynes

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Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart by Jacquelyn M. Walejko, Bridgette A. Christopher, Scott B. Crown, Guo-Fang Zhang, Adrian Pickar-Oliver, Takeshi Yoneshiro, Matthew W. Foster, Stephani Page, Stephan van Vliet, Olga Ilkayeva, Michael J. Muehlbauer, Matthew W. Carson, Joseph T. Brozinick, Craig D. Hammond, Ruth E. Gimeno, M. Arthur Moseley, Shingo Kajimura, Charles A. Gersbach, Christopher B. Newgard, Phillip J. White, Robert W. McGarrah

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Intrasession Repeatability of OCT Angiography Parameters in Neurodegenerative Disease by Dennis Y. Akrobetu, MD, Cason B. Robbins, MD, Justin P. Ma, MD, Srinath Soundararajan, BS, Michael S. Quist, MD, Sandra S. Stinnett, DrPH, Kathryn P.L. Moore, MD, MSc, Kim G. Johnson, MD, Andy J. Liu, MD, Dilraj S. Grewal, MD, FASRS, Sharon Fekrat, MD, FASRS

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Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine by Dapeng Li, David R. Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L. Sutherland, Esther Lee, Robert Parks, Dieter Mielke, Whitney Edwards, Amanda Newman, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Matthew Gagne, Daniel C. Douek, C. Todd DeMarco, Thomas N. Denny, Thomas H. Oguin, Alecia Brown, Wes Rountree, Yunfei Wang, Katayoun Mansouri, Robert J. Edwards, Guido Ferrari, Gregory D. Sempowski, Amanda Eaton, Juanjie Tang, Derek W. Cain, Sampa Santra, Norbert Pardi, Drew Weissman, Mark A. Tomai, Christopher B. Fox, Ian N. Moore, Hanne Andersen, Mark G. Lewis, Hana Golding, Robert Seder, Surender Khurana, Ralph S. Baric, David C. Montefiori, Kevin O. Saunders, Barton F. Haynes

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The COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS by Ga I. Ban, Vijitha Puviindran, Yu Xiang, Puvi Nadesan, Jackie Tang, Jianhong Ou, Nicholas Guardino, Makoto Nakagawa, MaKenna Browne, Asjah Wallace, Koji Ishikawa, Eijiro Shimada, John T. Martin, Yarui Diao, David G. Kirsch, Benjamin A. Alman

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Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response by Lianmei Tan, Tao Yin, Handan Xiang, Liuyang Wang, Poorva Mudgal, Junying Chen, Yi Ding, Guoping Wang, Bryan Jian Wei Lim, Yuqi Huang, De Huang, Yaosi Liang, Peter B. Alexander, Kun Xiang, Ergang Wang, Chengsong Yan, Zhehao Ma, Minjia Tan, Qi-Jing Li, Xiao-Fan Wang

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Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development by Jason T Long, Abigail Leinroth, Yihan Liao, Yinshi Ren, Anthony J Mirando, Tuyet Nguyen, Wendi Guo, Deepika Sharma, Douglas Rouse, Colleen Wu, Kathryn Song Eng Cheah, Courtney M Karner, Matthew J Hilton

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Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques by Justin Pollara, Justin Pollara, Matthew Zirui Tay, R. Whitney Edwards, Derrick Goodman, Andrew R. Crowley, Robert J. Edwards, David Easterhoff, Haleigh E. Conley, Taylor Hoxie, Thaddeus Gurley, Caroline Jones, Emily Machiele, Marina Tuyishime, Elizabeth Donahue, Shalini Jha, Rachel L. Spreng, Thomas J. Hope, Kevin Wiehe, Max M. He, M. Anthony Moody, Kevin O. Saunders, Kevin O. Saunders, Margaret E. Ackerman, Guido Ferrari, Guido Ferrari, Georgia D. Tomaras, Georgia D. Tomaras

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Targeting Neuroinflammation with Human Umbilical Cord Tissue‐Derived Mesenchymal Stromal Cells by Hyunjung Min, Arjun Saha, Li Xu, Melina Lillich, Roberta Parrott, Norin Meadows, Austin Rudisill, Joanne Kurtzberg, Anthony J. Filiano

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