A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae by Oriol Gallego, Matthew J Betts, Jelena Gvozdenovic‐Jeremic, Kenji Maeda, Christian Matetzki, Carmen Aguilar‐Gurrieri, Pedro Beltran‐Alvarez, Stefan Bonn, Carlos Fernández‐Tornero, Lars Juhl Jensen, Michael Kuhn, Jamie Trott, Vladimir Rybin, Christoph W Müller, Peer Bork, Marko Kaksonen, Robert B Russell, Anne‐Claude Gavin

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P1218: A REPROGRAMMING OF THE LYMPH NODE MICROENVIRONMENT UNDERLIES LOSS OF COMPARTMENTALISATION IN AGGRESSIVE LYMPHOMAS by Anna Mathioudaki, Felix Czernilofsky, Lea Jopp-Saile, Raphael Lutz, Dominik Vonflicht, XI Wang, Marc-A. Baertsch, Harald Vohringer, Tobias Roider, Johannes Mammen, Diana Ordonez-Rueda, Caroline Pabst, Wolfgang Huber, Andreas Trumpp, Carsten Müller-Tidow, Gary P. Nolan, Vladimir Benes, Judith B. Zaugg, Daniel Hübschmann, Simon Haas, Sascha Dietrich

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Crosshair, semi-automated targeting for electron microscopy with a motorised ultramicrotome by Kimberly Meechan, Wei Guan, Alfons Riedinger, Vera Stankova, Azumi Yoshimura, Rosa Pipitone, Arthur Milberger, Helmuth Schaar, Inés Romero-Brey, Rachel Templin, Christopher J Peddie, Nicole L Schieber, Martin L Jones, Lucy Collinson, Yannick Schwab

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SARS‐CoV‐2 infection remodels the host protein thermal stability landscape by Joel Selkrig, Megan Stanifer, André Mateus, Karin Mitosch, Inigo Barrio‐Hernandez, Mandy Rettel, Heeyoung Kim, Carlos G P Voogdt, Philipp Walch, Carmon Kee, Nils Kurzawa, Frank Stein, Clément Potel, Anna Jarzab, Bernhard Kuster, Ralf Bartenschlager, Steeve Boulant, Pedro Beltrao, Athanasios Typas, Mikhail M Savitski

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Metabolic memory underlying minimal residual disease in breast cancer by Ksenija Radic Shechter, Eleni Kafkia, Katharina Zirngibl, Sylwia Gawrzak, Ashna Alladin, Daniel Machado, Christian Lüchtenborg, Daniel C Sévin, Britta Brügger, Kiran R Patil, Martin Jechlinger

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Tracking cells in epithelial acini by light sheet microscopy reveals proximity effects in breast cancer initiation by Ashna Alladin, Lucas Chaible, Lucia Garcia del Valle, Reither Sabine, Monika Loeschinger, Malte Wachsmuth, Jean-Karim Hériché, Christian Tischer, Martin Jechlinger

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Lessons from a 2-Hub Life-Science Training Course: From Heidelberg to Bangalore and Beyond by Irena Provazníková, Nathalie Sneider, Swetlana Krez, Maria Bacadare Goitia, Juergen Deka, Elizabeth Zielonka

“…Here we present a novel 2-hub course format, with teaching of cutting-edge technologies simultaneously in Germany (EMBL Heidelberg) and India (BLiSC in Bangalore). The format combines active-based learning on a scientific case study with collaborative exercises and networking that foster scientific exchange. …”
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Characterization of drug‐induced transcriptional modules: towards drug repositioning and functional understanding by Murat Iskar, Georg Zeller, Peter Blattmann, Monica Campillos, Michael Kuhn, Katarzyna H Kaminska, Heiko Runz, Anne‐Claude Gavin, Rainer Pepperkok, Vera van Noort, Peer Bork

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Comparative chromatin accessibility upon BDNF stimulation delineates neuronal regulatory elements by Ignacio L Ibarra, Vikram S Ratnu, Lucia Gordillo, In‐Young Hwang, Luca Mariani, Kathryn Weinand, Henrik M Hammarén, Jennifer Heck, Martha L Bulyk, Mikhail M Savitski, Judith B Zaugg, Kyung‐Min Noh

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Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes by Natalia Wesolowska, Ivan Avilov, Pedro Machado, Celina Geiss, Hiroshi Kondo, Masashi Mori, Peter Lenart

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Randomly barcoded transposon mutant libraries for gut commensals II: Applying libraries for functional genetics by Carlos Geert Pieter Voogdt, Surya Tripathi, Stefan Oliver Bassler, Saria A. McKeithen-Mead, Emma R. Guiberson, Alexandra Koumoutsi, Afonso Martins Bravo, Cullen Buie, Michael Zimmermann, Justin L. Sonnenburg, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang

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Predictive features of gene expression variation reveal mechanistic link with differential expression by Olga M Sigalova, Amirreza Shaeiri, Mattia Forneris, Eileen EM Furlong, Judith B Zaugg

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Chromatin accessibility landscape of pediatric T‐lymphoblastic leukemia and human T‐cell precursors by Büşra Erarslan‐Uysal, Joachim B Kunz, Tobias Rausch, Paulina Richter‐Pechańska, Ianthe AEM vanBelzen, Viktoras Frismantas, Beat Bornhauser, Diana Ordoñez‐Rueada, Malte Paulsen, Vladimir Benes, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner‐Schwabe, Cornelia Eckert, Tsvetomir Loukanov, Matthias Gorenflo, Sebastian M Waszak, Jean‐Pierre Bourquin, Martina U Muckenthaler, Jan O Korbel, Andreas E Kulozik

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Increasing quantitation in spatial single-cell metabolomics by using fluorescence as ground truth by Martijn R. Molenaar, Mohammed Shahraz, Jeany Delafiori, Jeany Delafiori, Andreas Eisenbarth, Måns Ekelöf, Luca Rappez, Luca Rappez, Theodore Alexandrov, Theodore Alexandrov, Theodore Alexandrov, Theodore Alexandrov

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Nutritional stress-induced regulation of microtubule organization and mRNP transport by HDAC1 controlled α-tubulin acetylation by Frank Wippich, Vaishali, Marco L. Hennrich, Anne Ephrussi

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Phenotype inference in an Escherichia coli strain panel by Marco Galardini, Alexandra Koumoutsi, Lucia Herrera-Dominguez, Juan Antonio Cordero Varela, Anja Telzerow, Omar Wagih, Morgane Wartel, Olivier Clermont, Erick Denamur, Athanasios Typas, Pedro Beltrao

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Quantification of cytosolic interactions identifies Ede1 oligomers as key organizers of endocytosis by Dominik Boeke, Susanne Trautmann, Matthias Meurer, Malte Wachsmuth, Camilla Godlee, Michael Knop, Marko Kaksonen

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Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction by Surya Tripathi, Carlos Geert Pieter Voogdt, Stefan Oliver Bassler, Mary Anderson, Po-Hsun Huang, Nazgul Sakenova, Tümay Capraz, Sunit Jain, Alexandra Koumoutsi, Afonso Martins Bravo, Valentine Trotter, Michael Zimmerman, Justin L. Sonnenburg, Cullen Buie, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang

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PB1790: LOOKING ‘BENEATH’ THE SURFACE: PROTEOMICS AND GLYCIPROTEOMICS REVEAL NOVEL TARGETS FOR CAR-T CELL THERAPIES IN ACUTE MYELOID LEUKEMIA (AML) by Josephine Brysting, Yi Liu, Joris Frenz, Jennifer Schwarz, Tim Sauer, Michael Schmitt, Simon Raffel, Simon Renders, Judith B. Zaugg, Ashok Jayavely, Carsten Müller-Tidow

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The augmin complex architecture reveals structural insights into microtubule branching by Erik Zupa, Martin Würtz, Annett Neuner, Thomas Hoffmann, Mandy Rettel, Anna Böhler, Bram J. A. Vermeulen, Sebastian Eustermann, Elmar Schiebel, Stefan Pfeffer

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