Associations between gestational age at birth and infection-related hospital admission rates during childhood in England: Population-based record linkage study by Coathup, V, Carson, C, Kurinczuk, JJ, Macfarlane, AJ, Boyle, E, Johnson, S, Petrou, S, Quigley, MA

“…Effective infection prevention strategies should include focus on reducing the number and severity of LRTIs during early childhood.…”

Asia–Pacific consensus statement on integrated 24-hour activity guidelines for the early yearsResearch in context by Benny Kai Guo Loo, Anthony Okely, Rachael Taylor, Rachel Novotny, Pujitha Wickramasinghe, Falk Müller-Riemenschneider, Gade Waqa, Aman Pulungan, Satoshi Kusuda, Kok Hian Tan

“…Summary: Background: Early childhood is a vital period for development and growth. …”
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Development of the Chinese preschooler dietary index: a tool to assess overall diet quality by Xiaoyu Wang, Yujie Xu, Bingbing Tan, Ruonan Duan, Shufang Shan, Linan Zeng, Kun Zou, Li Zhao, Jingyuan Xiong, Lingli Zhang, Shuang Rong, Guo Cheng

“…Abstract Background Diet quality in early childhood has a long-term impact on health outcomes. …”
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Individualised stepwise adaptive treatment for 3–6-year-old preschool children impaired by attention-deficit/hyperactivity disorder (ESCApreschool): study protocol of an adaptive i... by Katja Becker, Tobias Banaschewski, Daniel Brandeis, Christina Dose, Christopher Hautmann, Martin Holtmann, Thomas Jans, Lea Jendreizik, Carolin Jenkner, Katja John, Johanna Ketter, Sabina Millenet, Ursula Pauli-Pott, Tobias Renner, Marcel Romanos, Anne-Katrin Treier, Elena von Wirth, Anne-Kathrin Wermter, Manfred Döpfner

“…Abstract Background Attention-deficit/hyperactivity disorder (ADHD) is a psychosocially impairing and cost-intensive mental disorder, with first symptoms occurring in early childhood. It can usually be diagnosed reliably at preschool age. …”
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Consenso para el diagnóstico, tratamiento y seguimiento del paciente con distrofia muscular de Duchenne by A. Nascimento Osorio, J. Medina Cantillo, A. Camacho Salas, M. Madruga Garrido, J.J. Vilchez Padilla

“…It is characterised by a progressive muscular weakness manifesting in early childhood, with the subsequent appearance of musculoskeletal, respiratory, and cardiac complications, causing disability, dependence, and premature death. …”
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Changes in visceral proteins pool in children with different types of respiratory failure by O.V. Filyk

“…Early nutritional disturbances may adversely affect the course of existing lung diseases in early childhood and increase the risk of lung disease in adults. …”
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Natural history of respiratory muscle strength in spinal muscular atrophy: a prospective national cohort study by Esther S. Veldhoen, Camiel A. Wijngaarde, Erik H. J. Hulzebos, Roelie M. Wösten-van Asperen, Renske I. Wadman, Ruben P. A. van Eijk, Fay Lynn Asselman, Marloes Stam, Louise A. M. Otto, Inge Cuppen, Feline E. V. Scheijmans, Laura P. Verweij-van den Oudenrijn, Bart Bartels, Michael A. Gaytant, Cornelis K. van der Ent, W. Ludo van der Pol

“…PEF reached values below 80% during early childhood in types 1c-2, and during adolescence in type 3a. …”
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Evaluation of Optimization of Pulmonary and Systemic Blood Flow in Children after Bidirectional Cavapulmonary Anastomosis by Ivan V. Dziuryi, Iaroslav P. Truba, Liliya M. Prokopovych, Vasyl V. Fylypchuk, Vasyl V. Lazoryshynets

“…The contribution of SVC flow to total cardiac output after bidirectional cavapulmonary anastomosis is directly associated with the patient’s age and gradually decreases in older patients, as indicated by a decrease in systemic saturation, so the clinical effect of bidirectional cavapulmonary anastomosis may be significantly better when performing surgery in early childhood.…”
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Prevalencia y factores asociados a infección por Helicobacter pylori en preescolares de La Habana, Cuba. Estudio de base poblacional by S.J. Venero-Fernández, I. Ávila-Ochoa, L. Menocal-Herredia, Y. Caraballo-Sánchez, F.M. Rosado-García, R. Suárez-Medina, P. Varona-Pérez, A.W. Fogarty

“…Conclusions: The prevalence of H. pylori infection in early childhood places Havana in an intermediate position at the international level. …”
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Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes by John S. House, John S. House, Michelle Mendez, Rachel L. Maguire, Rachel L. Maguire, Sarah Gonzalez-Nahm, Zhiqing Huang, Julie Daniels, Susan K. Murphy, Bernard F. Fuemmeler, Fred A. Wright, Fred A. Wright, Fred A. Wright, Fred A. Wright, Cathrine Hoyo, Cathrine Hoyo

“…Perinatal MDA score was associated with methylation differences for imprinted control regions of PEG10/SGCE [females: Beta (95% CI) = 1.66 (0.52, 2.80) – Bonferroni-corrected p = 0.048; males: -0.56 (-1.13, -0.00)], as well as both MEG3 and IGF2 in males [0.97 (0.00, 1.94)] and -0.92 (-1.65, -0.19) respectively.Conclusion: In this ethnically diverse cohort, maternal adherence to a Mediterranean diet in early pregnancy was associated with favorable neurobehavioral outcomes in early childhood and with sex-dependent methylation differences of MEG3, IGF2, and SGCE/PEG10 DMRs.…”
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A produção do conhecimento em terapia ocupacional na perspectiva da atenção integral à criança / The production of knowledge in occupational therapy in the perspective of comprehen... by Larissa Vendramini Nucci, Ana Célia Nunes, Débora Folha, Bruna Marini, Maysa Ramos, Patrícia Della Barba

“…</p><p><strong>Abstract</strong></p><p><strong> </strong></p><p>Child Development has been the target of investment in researches and practices focused on early childhood care. Currently, Brazil has incorporated public policies, laws and guidelines that ensure the children’s rights, considering the importance of intersectoral practices for the child’s integral care, ensuring the full development of their potential. …”
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IMPLEMENTASI MEDIA PEMBELAJARAN BERBASIS PRINSIP-PRINSIP PENDIDIKAN ORANG DEWASA PKBM INDONESIA PUSAKA NGALIYAN KOTA SEMARANG by Bagus Kisworo

“…</p><p> </p><p>The scope of activities in PKBM, kejar paket A, B, and C,  PAUD (early childhood education), KBU (group learning Efforts), KUPP (Productive Youth Business Group), women's empowerment, basic functional Adult Literacy, Reading public (Library). …”
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Valoración del documento de consenso sobre alimentación en centros educativos para evaluar menús escolares by Panmela Soares, María Asunción Martínez-Milán, Iris Comino, Pablo Caballero, Mari Carmen Davó-Blanes

“…Method: Transversal study that analyzes monthly school menus from 28 early-childhood education and primary education centres in Andalusia and Canary Islands (Spain). …”
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Arginine to ornithine ratio as a diagnostic marker in patients with positive newborn screening for hyperargininemia by Yue Huang, Rajesh Sharma, Annette Feigenbaum, Chung Lee, Inderneel Sahai, Rossana Sanchez Russo, Juanita Neira, Susan Sklower Brooks, Kelly E. Jackson, Derek Wong, Stephen Cederbaum, Felicitas L. Lacbawan, Charles M. Rowland, Pranoot Tanpaiboon, Denise Salazar

“…Untreated individuals often present with episodic hyperammonemia, developmental delay, cognitive impairment, and spasticity in early childhood. The newborn screening (NBS) algorithms for arginase deficiency vary between individual states in the US but often include hyperargininemia and elevated arginine to ornithine (Arg/Orn) ratio. …”
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Long-term impact of pre-incision antibiotics on children born by caesarean section: a longitudinal study based on UK electronic health records by Dana Šumilo, Krishnarajah Nirantharakumar, Brian H Willis, Gavin M Rudge, James Martin, Krishna Gokhale, Rasiah Thayakaran, Nicola J Adderley, Joht Singh Chandan, Kelvin Okoth, Isobel M Harris, Ruth Hewston, Magdalena Skrybant, Jonathan J Deeks, Peter Brocklehurst

“…Conclusions: There was no evidence that the policy change from post-cord clamping to pre-incision prophylactic antibiotics for caesarean sections during 2006–18 had an impact on the incidence of asthma and eczema in early childhood in the UK. Future work: There is a need for further research to investigate if pre-incision antibiotics have any impact on developing asthma and other allergy and immune-related conditions in older children. …”
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Severe impact of late diagnosis of congenital adrenal hyperplasia on gender identity, sexual orientation and function: case report and review of the literature by Chiara Simeoli, Cristina de Angelis, Alessandra Delli Veneri, Alessandra Delli Veneri, Davide Menafra, Nicola Di Paola, Claudia Pivonello, Claudia Pivonello, Carolina Di Somma, Paolo Valerio, Daniela Melis, Carlo Alviggi, Annamaria Colao, Annamaria Colao, Rosario Pivonello, Rosario Pivonello, Rosario Pivonello

“…In the majority of cases, particularly in developed countries, female patients suffering from the classic forms of CAH reach the diagnosis at birth or in the early childhood, allowing a prompt treatment with a correct gender assignment. …”
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Experience of Surgical Treatment of Complex Forms of Ebstein’s Anomaly through the Method of Hemodynamic Correction by Ivan V. Dziuryi, Iaroslav P. Truba, Oleksandr S. Golovenko, Iryna A. Perepeka, Vasyl V. Lazoryshynets

“…At this stage of the development of EA surgery, significant progress has been made in our understanding and treatment of EA, but the question of the tactics of treating complex forms, especially in the period of infancy and early childhood, remains open. Due to significant phenotypic heterogeneity, the treatment of EA varies greatly from patient to patient and depends on many factors that require a comprehensive approach. …”
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Upregulation of Protein Synthesis and Proteasome Degradation Confers Sensitivity to Proteasome Inhibitor Bortezomib in Myc-Atypical Teratoid/Rhabdoid Tumors by Huy Minh Tran, Kuo-Sheng Wu, Shian-Ying Sung, Chun Austin Changou, Tsung-Han Hsieh, Yun-Ru Liu, Yen-Lin Liu, Min-Lan Tsai, Hsin-Lun Lee, Kevin Li-Chun Hsieh, Wen-Chang Huang, Muh-Lii Liang, Hsin-Hung Chen, Yi-Yen Lee, Shih-Chieh Lin, Donald Ming-Tak Ho, Feng-Chi Chang, Meng-En Chao, Wan Chen, Shing-Shung Chu, Alice L. Yu, Yun Yen, Che-Chang Chang, Tai-Tong Wong

“…Atypical teratoid rhabdoid tumors (ATRTs) are among the most malignant brain tumors in early childhood and remain incurable. Myc-ATRT is driven by the <i>Myc</i> oncogene, which directly controls the intracellular protein synthesis rate. …”
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Vagus Nerve Stimulation Therapy for the Treatment of Seizures in Refractory Postencephalitic Epilepsy: A Retrospective Study by Yulin Sun, Yulin Sun, Jian Chen, Jian Chen, Tie Fang, Lin Wan, Lin Wan, Xiuyu Shi, Xiuyu Shi, Xiuyu Shi, Jing Wang, Jing Wang, Zhichao Li, Zhichao Li, Jiaxin Wang, Jiaxin Wang, Zhiqiang Cui, Xin Xu, Zhipei Ling, Liping Zou, Liping Zou, Guang Yang, Guang Yang, Guang Yang

“…VNS efficacy was evaluated based on seizure reduction, effective rate (percentage of cases with seizure reduction ≥ 50%), McHugh classification, modified Early Childhood Epilepsy Severity Scale (E-Chess) score, and Grand Total EEG (GTE) score. …”
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Représenter la dimension spatiale des contextes d'exercice des professionnels intervenant auprès des migrants : le cas des interprètes by Anne-Cécile Hoyez, Anaïk Pian, Pascal Jarno, Arnaud Lepetit

“…As highlighted by the cartographic part of the study, interpreters are asked to practice in a plurality of institutions with different interlocutors, which implies heterogeneous interpreting situations and the mobilisation of a wide range of language practices (related to the medical field, asylum, early childhood, etc.). Thus, an interpreter can ensure in one day a pediatric consultation, an intervention in shelter for asylum seekers then go to a cancer department where the medical appointment will concern a diagnostic announcement. …”
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