Current diagnosis and management of toddler's fracture by Sandra Llorente Pelayo, Juan Rodríguez Fernández, M. Teresa Leonardo Cabello, Mónica Rubio Lorenzo, M. Dolores García Alfaro, Carmelo Arbona Jiménez

“…Introduction: Toddler's fracture is an accidental spiral tibial fracture, characteristic of the early childhood. The objective of this study is to determine the incidence and current diagnosis and management of this disorder. …”
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PIK3CA-Related Overgrowth Spectrum From Diagnosis to Targeted Therapy: A Case of CLOVES Syndrome Treated With Alpelisib by Angelica Pagliazzi, Teresa Oranges, Giovanna Traficante, Chiara Trapani, Flavio Facchini, Alessandra Martin, Alessandro Semeraro, Anna Perrone, Cesare Filippeschi, Sabrina Giglio, Sabrina Giglio

“…The common clinical denominator of PROS disorders is that they are sporadic conditions, presenting with congenital or early childhood onset overgrowth with a typical mosaic distribution. …”
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Infant formula enriched with milk fat globule membrane, long-chain polyunsaturated fatty acids, synbiotics, gangliosides, nucleotides and sialic acid reduces infections during the... by Florian Herrmann, Ana Nieto-Ruiz, Natalia Sepúlveda-Valbuena, M. Teresa Miranda, Estefanía Diéguez, Jesús Jiménez, Roser De-Castellar, María García-Ricobaraza, José Antonio García-Santos, Mercedes G. Bermúdez, Cristina Campoy

“…Functional nutrients like synbiotics or milk-fat globule membrane (MFGM) affect positively host immunity, modifying intestinal microbioma and reducing early childhood infections. We compared effects of an experimental enriched-infant formula with long chain polyunsaturated fatty acids, MFGM, synbiotics, sialic acid, nucleotides and gangliosides to a standard infant formula and breastfeeding regarding infections incidence and evolution in infants until 18 months of age. 170 healthy infants were enrolled in a RCT to receive either a bioactive functional nutrients enriched infant formula (EF, n = 85) or a standard formula (SF, n = 85). 50 breastfed (BF) infants were also enrolled. …”
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Valoración del documento de consenso sobre alimentación en centros educativos para evaluar menús escolares by Panmela Soares, María Asunción Martínez-Milán, Iris Comino Comino, Pablo Caballero, Mari Carmen Davó-Blanes

“…Summary: Objective: To explore the applicability of the Consensus Document on School Food Programmes in Educational Centres (DCSECE) to evaluate the adaptation of school menus to healthy eating recommendations.Method: Transversal study that analyzes monthly school menus from 28 early-childhood education and primary education centres in Andalusia and Canary Islands (Spain). …”
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Do effects of early life interventions on linear growth correspond to effects on neurobehavioural development? A systematic review and meta-analysis by Elizabeth L Prado, PhD, Leila M Larson, PhD, Katherine Cox, MPH, Kory Bettencourt, MS, Julianne N Kubes, MPH, Anuraj H Shankar, DSc

“…Summary: Background: Faltering in linear growth and neurobehavioural development during early childhood are often assumed to have common causes because of their consistent association. …”
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Relations between bedtime parenting behaviors and temperament across 14 cultures by Christie Pham, Eric Desmarais, Victoria Jones, Brian F. French, Zhengyan Wang, Samuel Putnam, Sara Casalin, Maria Beatriz Martins Linhares, Felipe Lecannelier, Soile Tuovinen, Soile Tuovinen, Kati Heinonen, Kati Heinonen, Katri Raikkonen, Rosario Montirosso, Lorenzo Giusti, Seong-Yeon Park, Sae-Young Han, Eun Gyoung Lee, Eun Gyoung Lee, Blanca Huitron, Carolina de Weerth, Roseriet Beijers, Roseriet Beijers, Mirjana Majdandžić, Carmen Gonzalez-Salinas, Ibrahim Acar, Helena Slobodskaya, Elena Kozlova, Emine Ahmetoglu, Oana Benga, Maria A. Gartstein

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Participants’ Engagement With Telephone Support Interventions to Promote Healthy Feeding Practices and Obesity-Protective Behaviours for Infant Obesity Prevention by Mahalakshmi Ekambareshwar, Mahalakshmi Ekambareshwar, Huilan Xu, Chris Rissel, Chris Rissel, Louise Baur, Louise Baur, Louise Baur, Louise Baur, Sarah Taki, Sarah Taki, Seema Mihrshahi, Seema Mihrshahi, Li Ming Wen, Li Ming Wen, Li Ming Wen

“…The aim of this research was to investigate participant engagement with the Communicating Healthy Beginnings Advice by Telephone (CHAT) program, an early childhood obesity prevention program that included interventions for promoting healthy infant feeding practices and obesity-protective behaviours via telephone, and whether engagement with the telephone support program varied by participants’ sociodemographic characteristics.MethodsThis study used de-identified CHAT program data of participants who received the interventions via telephone. …”
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Genetic Insights from Consanguineous Cardiomyopathy Families by Constance Maurer, Olga Boleti, Paria Najarzadeh Torbati, Farzaneh Norouzi, Anna Nicole Rebekah Fowler, Shima Minaee, Khalid Hama Salih, Mehdi Taherpour, Hassan Birjandi, Behzad Alizadeh, Aso Faeq Salih, Moniba Bijari, Henry Houlden, Alan Michael Pittman, Reza Maroofian, Yahya H. Almashham, Ehsan Ghayoor Karimiani, Juan Pablo Kaski, Eissa Ali Faqeih, Farveh Vakilian, Yalda Jamshidi

“…Co-segregation analysis in family members confirmed autosomal recessive inheritance presenting in early childhood/early adulthood. Our findings add to the mutational spectrum of recessive cardiomyopathies, supporting inclusion of <i>KLHL24</i>, <i>NRAP</i> and <i>RBCK1</i> as disease-causing genes. …”
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Prenatal Exposure to Traffic Pollution and Childhood Body Mass Index Trajectory by Abby F. Fleisch, Abby F. Fleisch, Izzuddin M. Aris, Izzuddin M. Aris, Sheryl L. Rifas-Shiman, Brent A. Coull, Heike Luttmann-Gibson, Petros Koutrakis, Joel D. Schwartz, Itai Kloog, Itai Kloog, Diane R. Gold, Diane R. Gold, Emily Oken, Emily Oken

“…For example, greater neighborhood traffic density [median (IQR) 857 (1,452) vehicles/day x km of road within 100 m of residential address at delivery] was associated with a higher BMI throughout childhood, with the strongest associations in early childhood [e.g., per IQR increment natural log-transformed neighborhood traffic density, BMI at 12 months of age was 0.05 (−0.03, 0.13) kg/m2 higher and infancy peak BMI was 0.05 (−0.03, 0.14) kg/m2 higher].Conclusions: We found no evidence for a persistent effect of prenatal exposure to traffic pollution on BMI trajectory from birth through mid-childhood in a population exposed to modest levels of air pollution.…”
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Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mot... by Delphina Gomes, Rüdiger von Kries, Maria Delius, Ulrich Mansmann, Martha Nast, Martina Stubert, Lena Langhammer, Nikolaus A Haas, Heinrich Netz, Viola Obermeier, Stefan Kuhle, Lesca M Holdt, Daniel Teupser, Uwe Hasbargen, Adelbert A Roscher, Regina Ensenauer

“…Besides higher birth weight (Δ 192 g, 95% CI 100-284) and cord-blood C-peptide concentration (Δ 0.10 ng/ml, 95% CI 0.02-0.17), offspring of these women had greater weight gain during early childhood (Δ BMI z-score per year 0.18, 95% CI 0.06-0.30, n = 262) and higher BMI z-score at 4 years (Δ 0.58, 95% CI 0.18-0.99, n = 43) than offspring of the obese, GDM-negative mothers with normal HbA1c values at delivery. …”
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CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out by Anna Dal Molin, Mattias Hofmans, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Alessia Buratin, Hélène Cavé, Hélène Cavé, Christian Flotho, Valerie de Haas, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, Pieter Van Vlierberghe, Jan Philippé, Jan Philippé, Barbara De Moerloose, Barbara De Moerloose, Geertruij te Kronnie, Silvia Bresolin, Silvia Bresolin, Tim Lammens, Tim Lammens, Stefania Bortoluzzi, Stefania Bortoluzzi

“…Juvenile myelomonocytic leukemia (JMML), a rare myelodysplastic/myeloproliferative neoplasm of early childhood, is characterized by clonal growth of RAS signaling addicted stem cells. …”
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Serotonin transporter gene (SLC6A4) polymorphism and susceptibility to a home-visiting maternal-infant attachment intervention delivered by community health workers in South Africa... by Barak Morgan, Robert Kumsta, Pasco Fearon, Dirk Moser, Sarah Skeen, Peter Cooper, Lynne Murray, Greg Moran, Mark Tomlinson

“…<h4>Background</h4>Clear recognition of the damaging effects of poverty on early childhood development has fueled an interest in interventions aimed at mitigating these harmful consequences. …”
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Evaluación de pares y autoevaluación con erúbricas: caso de estudio en el grado de Educación Primaria by Rafael Pérez Galán, Daniel Cebrián Robles, Ana B. Rueda Galiano

“…</p><p><strong>ABSTRACT</strong></p><p><strong>Peer assessment and self-evaluation with erubrics: a case study in the Degree in Early Childhood Education.</strong></p><p>This paper analyzes the extent to which students are able to assess their own learning and that of their peers (peer assessment and self-evaluation) through erubrica, standards and evaluation criteria proposed by the faculty in the configuration, design and development of project evaluation. …”
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Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies. by Johan L Vinther, Tim Cadman, Demetris Avraam, Claus T Ekstrøm, Thorkild I A Sørensen, Ahmed Elhakeem, Ana C Santos, Angela Pinot de Moira, Barbara Heude, Carmen Iñiguez, Costanza Pizzi, Elinor Simons, Ellis Voerman, Eva Corpeleijn, Faryal Zariouh, Gilian Santorelli, Hazel M Inskip, Henrique Barros, Jennie Carson, Jennifer R Harris, Johanna L Nader, Justiina Ronkainen, Katrine Strandberg-Larsen, Loreto Santa-Marina, Lucinda Calas, Luise Cederkvist, Maja Popovic, Marie-Aline Charles, Marieke Welten, Martine Vrijheid, Meghan Azad, Padmaja Subbarao, Paul Burton, Puishkumar J Mandhane, Rae-Chi Huang, Rebecca C Wilson, Sido Haakma, Sílvia Fernández-Barrés, Stuart Turvey, Susana Santos, Suzanne C Tough, Sylvain Sebert, Theo J Moraes, Theodosia Salika, Vincent W V Jaddoe, Deborah A Lawlor, Anne-Marie Nybo Andersen

“…Using a federated analytical tool (DataSHIELD), we fitted linear and logistic regression models in each cohort separately with a complete-case approach and combined the regression estimates and standard errors through random-effects study-level meta-analysis providing an overall effect estimate at early infancy (>0.0 to 0.5 years), late infancy (>0.5 to 2.0 years), early childhood (>2.0 to 5.0 years), mid-childhood (>5.0 to 9.0 years), late childhood (>9.0 to 14.0 years), and adolescence (>14.0 to 19.0 years). …”
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Phonological working memory and finiteness marking in typical development by Ostrovskaya, Irina

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新加坡英汉双语儿童常用身体动词习得情况研究 = A study of the acquisition of commonly used physical action verbs by English-Chinese bilingual children in Singapore... by 黄玮婷 Wong, Wei Ting

“…本研究希望通过此调查结果了解新加坡儿童的语言使用情况及双语发展，同时也为今后新加坡学前与小学生的语言教学提供参考。Bilingualism in early childhood is a widely-debated topic with several schools of thoughts. …”
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Factors associated with cognitive and motor development among infants aged 6 to 12 months in Seremban, Negeri Sembilan, Malaysia by Sabri, Nur 'Amirah 'Inani

“…In conclusion, high prevalence of cognitive and motor developmental delays among infants aged 6 to 12 months in this study highlights the need for early identification and interventions in order to improve early childhood development. An advocacy effort is needed for implementing early intervention programs involving parents, communities and government agencies to improve cognitive and motor development of infants. …”
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تصنيف أسباب البيلة الدموية عند الأطفال لمراجعي مشفى الأسد الجامعي خلال مدة عام by عزيز زاهر, إسلام ياسين قصاب, سوسن محمد

“…They were distributed as: 74male and 98female, their ages were as: 48 children in early childhood, 77children in preschool age, 39children in school age and 8 children were between 13-15years. …”
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Glucocorticoid Receptor Gene (<i>NR3C1</i>) Polymorphisms and Metabolic Syndrome: Insights from the Mennonite Population by Kathleen Liedtke Kolb, Ana Luiza Sprotte Mira, Eduardo Delabio Auer, Isabela Dall’Oglio Bucco, Carla Eduarda de Lima e Silva, Priscila Ianzen dos Santos, Valéria Bumiller-Bini Hoch, Luana Caroline Oliveira, Aline Borsato Hauser, Jennifer Elisabeth Hundt, Alan R. Shuldiner, Fabiana Leão Lopes, Teide-Jens Boysen, Andre Franke, Luis Felipe Ribeiro Pinto, Sheila Coelho Soares-Lima, Gabriela Canalli Kretzschmar, Angelica Beate Winter Boldt

“…Thus, <i>NR3C1</i> polymorphisms seem to modulate the susceptibility to MetS in Mennonites, independently of lifestyle and early childhood events, and their role seems to be unrelated to DNA methylation and gene expression.…”
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Prevalence and risk factors of molar incisor hypomineralization in the Middle East: A systematic review and meta-analysis by Sara T. Bukhari, MS, Hussain A. Alhasan, MS, Majd T. Qari, MS, Heba J. Sabbagh, PhD, Najat M. Farsi, PhD

“…The frequency of MIH reported in the ME ranged from 2.3% to 40.7%, with a mean prevalence of 15.05%. Pregnancy and early childhood illnesses (odds ratio [OR]: 2.26, 95% confidence interval [CI]: 1.91–2.68; P < 0.001) and factors related to delivery (OR: 2.4, 95% CI: 1.55–3.72; P < 0.001) were statically significantly associated with MIH. …”
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