Early life exposures contributing to accelerated lung function decline in adulthood – a follow-up study of 11,000 adults from the general populationResearch in context by Jorunn Kirkeleit, Trond Riise, Mathias Wielscher, Simone Accordini, Anne-Elie Carsin, Julie Dratva, Karl A. Franklin, Judith Garcia-Aymerich, Deborah Jarvis, Benedicte Leynaert, Caroline J. Lodge, Francisco Gomez Real, Vivi Schlünssen, Angelo Guido Corsico, Joachim Heinrich, Matthias Holm, Christer Janson, Bryndis Benediktsdóttir, Rain Jogi, Shyamali C. Dharmage, Marjo-Riitta Järvelin, Cecilie Svanes

“…Severe respiratory infections in early childhood were associated with accelerated decline among ever-smokers. …”
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Effect of Recombinant Gonadotropin on Testicular Function and Testicular Sperm Extraction in Five Cases of NR0B1 (DAX1) Pathogenic Variants by Jordan Teoli, Jordan Teoli, Jordan Teoli, Vincent Mezzarobba, Lucie Renault, Delphine Mallet, Hervé Lejeune, Hervé Lejeune, Hervé Lejeune, Pierre Chatelain, Pierre Chatelain, Frédérique Tixier, Marc Nicolino, Marc Nicolino, Noël Peretti, Noël Peretti, Sandrine Giscard D’estaing, Sandrine Giscard D’estaing, Sandrine Giscard D’estaing, Béatrice Cuzin, Frédérique Dijoud, Frédérique Dijoud, Frédérique Dijoud, Florence Roucher-Boulez, Florence Roucher-Boulez, Ingrid Plotton, Ingrid Plotton, Ingrid Plotton, Ingrid Plotton

“…BackgroundNR0B1 pathogenic variants can cause congenital adrenal hypoplasia or primary adrenal insufficiency in early childhood usually associated with hypogonadotropic hypogonadism. …”
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Novel and Founder Pathogenic Variants in X-Linked Alport Syndrome Families in Greece by Despina Hadjipanagi, Gregory Papagregoriou, Constantina Koutsofti, Christiana Polydorou, Polichronis Alivanis, Aimilios Andrikos, Stalo Christodoulidou, Manthos Dardamanis, Athanasios A. Diamantopoulos, Anastasios Fountoglou, Eleni Frangou, Eleni Georgaki, Ioannis Giannikouris, Velissarios Gkinis, Pavlos C. Goudas, Rigas G. Kalaitzidis, Nikolaos Kaperonis, Georgios Koutroumpas, George Makrydimas, Grigorios Myserlis, Andromachi Mitsioni, Christos Paliouras, Fotios Papachristou, Dorothea Papadopoulou, Nikolaos Papagalanis, Aikaterini Papagianni, Garyfalia Perysinaki, Ekaterini Siomou, Konstantinos Sombolos, Ioannis Tzanakis, Georgios V. Vergoulas, Nicoletta Printza, Constantinos Deltas

“…The disease manifests in early childhood with persistent microhematuria and can progress to proteinuria and kidney failure in adolescence or early adulthood if left untreated. …”
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Ambivalent character of leave policies development in Croatia: between pronatalist and gender equality agenda by Dobrotic, I

“…There was a clear shift from state-led promotion of dual-earner family model, which reposed on one-year maternity leave and for that time moderately developed early childhood education and care services, prefiguring in some respects the activation dimension of the social investment paradigm, towards the familialistic paradigm. …”

El Apego Va a Juicio: Problemas de Custodia y Protección Infantil1 by Tommie Forslund, Pehr Granqvist, Marinus H. van IJzendoorn, Avi Sagi-Schwartz, Danya Glaser, Miriam Steele, Mårten Hammarlund, Carlo Schuengel, Marian J. Bakermans-Kranenburg, Howard Steele, Phillip R. Shaver, Ulrike Lux, John Simmonds, Deborah Jacobvitz, Ashley M. Groh, Kristin Bernard, Chantal Cyr, Nancy L. Hazen, Sarah Foster, Elia Psouni, Philip A. Cowan, Carolyn Pape Cowan, Anne Rifkin-Graboi, David Wilkins, Blaise Pierrehumbert, George M. Tarabulsy, Rodrigo A. Cárcamo, Zhengyan Wang, Xi Liang, Maria Kázmierczak, Paulina Pawlicka, Lilian Ayiro, Tamara Chansa, Francis Sichimba, Haatembo Mooya, Loyola McLean, Manuela Verissimo, Sonia Gojman-de-Millán, Marlene M. Moretti, Fabien Bacro, Mikko J. Peltola, Megan Galbally, Kiyomi Kondo-Ikemura, Kazuko Y. Behrens, Stephen Scott, Andrés Fresno Rodriguez, Rosario Spencer, Germán Posada, Rosalinda Cassibba, Neus Barrantes-Vidal, Jesús Palacios, Lavinia Barone, Sheri Madigan, Karen Mason-Jones, Sophie Reijman, Femmie Juffer, R. Pasco Fearon, Annie Bernier, Dante Cicchetti, Glenn I. Roisman, Jude Cassidy, Heinz Kindler, Peter Zimmerman, Ruth Feldman, Gottfried Spangle, Charles H. Zeanah, Mary Dozier, Jay Belsky, Michael E. Lamb, Robbie Duschinsky

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Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies by Johan L. Vinther, Tim Cadman, Demetris Avraam, Claus T. Ekstrøm, Thorkild I. A. Sørensen, Ahmed Elhakeem, Ana C. Santos, Angela Pinot de Moira, Barbara Heude, Carmen Iñiguez, Costanza Pizzi, Elinor Simons, Ellis Voerman, Eva Corpeleijn, Faryal Zariouh, Gilian Santorelli, Hazel M. Inskip, Henrique Barros, Jennie Carson, Jennifer R. Harris, Johanna L. Nader, Justiina Ronkainen, Katrine Strandberg-Larsen, Loreto Santa-Marina, Lucinda Calas, Luise Cederkvist, Maja Popovic, Marie-Aline Charles, Marieke Welten, Martine Vrijheid, Meghan Azad, Padmaja Subbarao, Paul Burton, Puishkumar J. Mandhane, Rae-Chi Huang, Rebecca C. Wilson, Sido Haakma, Sílvia Fernández-Barrés, Stuart Turvey, Susana Santos, Suzanne C. Tough, Sylvain Sebert, Theo J. Moraes, Theodosia Salika, Vincent W. V. Jaddoe, Deborah A. Lawlor, Anne-Marie Nybo Andersen

“…Using a federated analytical tool (DataSHIELD), we fitted linear and logistic regression models in each cohort separately with a complete-case approach and combined the regression estimates and standard errors through random-effects study-level meta-analysis providing an overall effect estimate at early infancy (>0.0 to 0.5 years), late infancy (>0.5 to 2.0 years), early childhood (>2.0 to 5.0 years), mid-childhood (>5.0 to 9.0 years), late childhood (>9.0 to 14.0 years), and adolescence (>14.0 to 19.0 years). …”
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Watch me grow integrated (WMG-I): protocol for a cluster randomised controlled trial of a web-based surveillance approach for developmental screening in primary care settings by Pankaj Garg, Susan Woolfenden, Raghu Lingam, Bin Jalaludin, Teresa Winata, Andrew Page, Paul B Colditz, Valsamma Eapen, Siaw-Teng Liaw, Clare Thomas, Jane Kohlhoff, James G Scott, Elisabeth Murphy, Margo Pritchard, Helen Heussler, K D Lawson, Joseph Descallar, Chun Wah Michael Tam, Kerri-Lyn Webb, Christa Lam-Cassettari, Lisa Karlov, Natalie Ong, Robyn Littlewood, April Deering, Kate Short, Victoria Blight, Kim Rodgers, Lucille Chalmers, Heidi Atkins, Dana Newcomb, Rachael Beswick, Catherine Marron, Aaron Chambers, Sue Scheinpflug, Matt Statham, Dimuthu Samaranayake, Paul Chay, Feroza Khan, Antonio Mendoza Diaz, Sara Cibralic

“…Introduction The increasing prevalence of developmental disorders in early childhood poses a significant global health burden. …”
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Prenatal single and combined exposure to phthalates associated with girls’ BMI trajectory in the first six years by Hui Gao, Meng-long Geng, Hong Gan, Kun Huang, Cheng Zhang, Bei-bei Zhu, Li Sun, Xiulong Wu, Peng Zhu, Fang-biao Tao

“…In conclusion, in utero exposure to phthalates, including MEP and DEHP metabolites (MEHHP and MEOHP), was significantly associated with early childhood high BMI trajectories in girls. The third trimester of pregnancy seemed to be the window of vulnerability to phthalate exposure for girls’ high BMI trajectory at periods of prenatal development. …”
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Wpływ edukacji zdrowotnej na zachowania zdrowotne dzieci w wieku przedszkolnym w opinii rodziców = Health education influence on health behaviors of preschool children in the opini... by Dominik Olejniczak, Wioleta Święcka, Joanna Skonieczna, Grażyna Dykowska

“…Conclusions: Parents appreciate the role of early childhood care in the development and health of children. …”
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Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Bangladesh: a cluster randomised controlled trial by Stephen P Luby, ProfMD, Mahbubur Rahman, MBBS, Benjamin F Arnold, PhD, Leanne Unicomb, PhD, Sania Ashraf, MPH, Peter J Winch, ProfMD, Christine P Stewart, PhD, Farzana Begum, MPH, Faruqe Hussain, MSS, Jade Benjamin-Chung, PhD, Elli Leontsini, MD, Abu M Naser, MBBS, Sarker M Parvez, MPH, Alan E Hubbard, ProfPhD, Audrie Lin, PhD, Fosiul A Nizame, MA, Kaniz Jannat, MBBS, Ayse Ercumen, PhD, Pavani K Ram, MD, Kishor K Das, MS, Jaynal Abedin, MS, Thomas F Clasen, ProfPhD, Kathryn G Dewey, ProfPhD, Lia C Fernald, Prof, Clair Null, PhD, Tahmeed Ahmed, PhD, John M Colford, Jr, ProfMD

“…Summary: Background: Diarrhoea and growth faltering in early childhood are associated with subsequent adverse outcomes. …”
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Study Protocol for the COVID-19 Pandemic Adjustment Survey (CPAS): A Longitudinal Study of Australian Parents of a Child 0–18 Years by Elizabeth M. Westrupp, Gery Karantzas, Jacqui A. Macdonald, Jacqui A. Macdonald, Jacqui A. Macdonald, Lisa Olive, George Youssef, George Youssef, Christopher J. Greenwood, Christopher J. Greenwood, Emma Sciberras, Emma Sciberras, Emma Sciberras, Matthew Fuller-Tyszkiewicz, Subhadra Evans, Antonina Mikocka-Walus, Mathew Ling, Robert Cummins, Delyse Hutchinson, Delyse Hutchinson, Delyse Hutchinson, Delyse Hutchinson, Glenn Melvin, Glenn Melvin, Julian W. Fernando, Samantha Teague, Amanda G. Wood, Amanda G. Wood, Amanda G. Wood, John W. Toumbourou, Tomer Berkowitz, Jake Linardon, Jake Linardon, Peter G. Enticott, Mark A. Stokes, Jane McGillivray, Craig A. Olsson, Craig A. Olsson, Craig A. Olsson

“…Specifically, this study will investigate the extent to which the COVID-19 pandemic is associated with increased risk for parents’ mental health, lower well-being, loneliness, and alcohol use; parent-parent and parent-child relationships (both verbal and physical); and child and adolescent mental health problems.MethodsThe study aims to recruit a close to representative sample of at least 2,000 adults aged 18 years and over living in Australia who are parents of a child 0–4 years (early childhood, N = 400), 5–12 years (primary school N = 800), and 13–18 years (secondary school, N = 800). …”
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Wpływ edukacji zdrowotnej na zachowania zdrowotne dzieci w wieku przedszkolnym w opinii rodziców = Health education influence on health behaviors of preschool children in the opini... by Dominik Olejniczak, Wioleta Święcka, Joanna Skonieczna, Grażyna Dykowska

“…Conclusions: Parents appreciate the role of early childhood care in the development and health of children. …”
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Handbook of Research on Acquiring 21st Century Literacy Skills Through Game-Based Learning / by Lane, Carol-Ann, editor 651838, IGI Global (Online service) 631983

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THE COMPATIBILITY OF OUTDOOR STUDY APPLICATION OF ENVIRONMENTAL SUBJECT USING PSYCHOLOGICAL THEORIES OF INTELLIGENCE AND MEANINGFUL LEARNING IN SENIOR HIGH SCHOOL by Eko Harianto, La Ode Nursalam, Fahrudi Ahwan Ikhsan, Z Zakaria, D Damhuri, Andri Estining Sejati

“…Nature and The Outdoor Learning Environtment: The Forgotten Resource in Early Childhood Education. International Journal of Early Chilhood Environmental Education 3(1), 85-97. …”
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World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow’s Milk Allergy (DRACMA) Guideline update – XIV – Recommendations on CMA immunotherapy by Jan L. Brozek, Ramon T. Firmino, Antonio Bognanni, Stefania Arasi, Ignacio Ansotegui, Amal H. Assa'ad, Sami L. Bahna, Roberto Berni Canani, Martin Bozzola, Derek K. Chu, Lamia Dahdah, Christophe Dupont, Piotr Dziechciarz, Motohiro Ebisawa, Elena Galli, Andrea Horvath, Rose Kamenwa, Gideon Lack, Haiqi Li, Alberto Martelli, Anna Nowak-Węgrzyn, Nikolaos G. Papadopoulos, Ruby Pawankar, Yetiani Roldan, Maria Said, Mario Sánchez-Borges, Raanan Shamir, Jonathan M. Spergel, Hania Szajewska, Luigi Terracciano, Yvan Vandenplas, Carina Venter, Siw Waffenschmidt, Susan Waserman, Amena Warner, Gary W.K. Wong, Alessandro Fiocchi, Holger J. Schünemann

“…Most children outgrow cow's milk allergy in early childhood, particularly that to the baked milk products. …”
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Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment by Susana Navarro, Oscar Quintana-Bustamante, Rebeca Sanchez-Dominguez, Sergio Lopez-Manzaneda, Isabel Ojeda-Perez, Aida Garcia-Torralba, Omaira Alberquilla, Kenneth Law, Brian C. Beard, Antonella Bastone, Michael Rothe, Mariela Villanueva, Juan C. Ramirez, Sara Fañanas-Baquero, Virginia Nieto-Romero, Andrea Molinos-Vicente, Sonia Gutierrez, Eileen Nicoletti, María García-Bravo, Juan A. Bueren, Jonathan D. Schwartz, Jose-Carlos Segovia

“…PKD is characterized by non-spherocytic hemolytic anemia of variable severity and may be fatal in some cases during early childhood. Although not considered the standard of care, allogeneic stem cell transplantation has been shown as a potentially curative treatment, limited by donor availability, toxicity, and incomplete engraftment. …”
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Associations of cord plasma per- and polyfluoroakyl substances (PFAS) with neonatal and child body composition and adiposity: The GUSTO study by Ling-Wei Chen, Sharon Ng, Mya-Thway Tint, Navin Michael, Suresh Anand Sadananthan, Yi Ying Ong, Wen Lun Yuan, Ze-Ying Chen, Chia-Yang Chen, Keith M. Godfrey, Kok Hian Tan, Peter D. Gluckman, Yap-Seng Chong, Johan G. Eriksson, Fabian Yap, Yung Seng Lee, Marielle V. Fortier, Sendhil S. Velan, Shiao-Yng Chan

“…Further research is needed to replicate the findings and to determine if these effects may reappear beyond early childhood. Population exposure to newer PFAS and consequent health impact must be monitored.…”
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Mandatory Vaccines Will Not Ease Fears by Dallas Ducar

“…Santa Monica is a hotbed for vaccine debate. An early childhood center in Santa Monica is reported to have a personal belief exemption rate of over 65 percent. …”
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World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guideline update – XIII – Oral immunotherapy for CMA – Systematic review... by Antonio Bognanni, MD, Derek K. Chu, MD, Ramon T. Firmino, DDS, PhD, Stefania Arasi, PhD, MSc, Siw Waffenschmidt, Arnav Agarwal, MD, Piotr Dziechciarz, MD, PhD, Andrea Horvath, MD, PhD, Rime Jebai, MSc, MPH, Hanako Mihara, MD, MPH, Yetiani Roldan, MD, Maria Said, RN, Raanan Shamir, MD, PhD, Martin Bozzola, MD, Sami Bahna, MD, DrPH, Alessandro Fiocchi, MD, Susan Waserman, MD, MSc, Holger J. Schünemann, MD, MSc, PhD, Jan L. Brożek, MD, PhD, Ignacio J. Ansotegui, MD, PhD, Stefania Arasi, MD, PhD, Amal H. Assa'ad, MD, Sami L. Bahna, MD, DrPH, Roberto Berni Canani, MD, PhD, Antonio Bognanni, MD, Martin Bozzola, MD, Jan Brozek, MD, PhD, Derek K. Chu, MD, PhD, Lamia Dahdah, MD, Christophe Dupont, MD, PhD, Motohiro Ebisawa, MD, PhD, Alessandro Fiocchi, MD, Ramon Targino Firmino, MD, Elena Galli, MD, PhD, Rose Kamenwa, MD, Gideon Lack, MBBCh, Haiqi Li, MD, Alberto Martelli, MD, Anna H. Nowak-Wegrzyn, MD, PhD, Nikolaos G. Papadopoulos, MD, PhD, Ruby Pawankar, MD, PhD, Maria Said, RN, Mario Sánchez-Borges, MD, Holger J. Schünemann, MD, MSc, PhD, Raanan Shamir, MD, PhD, Jonathan M. Spergel, MD, PhD, Hania Szajewska, MD, Luigi Terracciano, MD, Yvan Vandenplas, MD, PhD, Carina Venter, PhD, RD, Amena Warner, RN, SN (PG Dip), Susan Waserman, MD, MSc, GaryW.K. Wong, MD

“…In some individuals it persists beyond early childhood. Oral immunotherapy (OIT, oral desensitization, specific oral tolerance induction) has been proposed as a promising therapeutic strategy for persistent IgE-mediated cow's milk allergy. …”
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Physical literacy in Europe: The current state of implementation in research, practice, and policy by Johannes Carl, Anna S. Bryant, Lowri C. Edwards, Gillian Bartle, Jens E. Birch, Efstathios Christodoulides, Arunas Emeljanovas, Andreas Fröberg, Joseph Gandrieau, Barbara Gilic, Ivo van Hilvoorde, Peter Holler, Teodora M. Iconomescu, Johannes Jaunig, Ida Laudanska-Krzeminska, Suzanne Lundvall, Kristine De Martelaer, João Martins, Brigita Mieziene, Maria Mendoza-Muñoz, Alexandre Mouton, Bogdan S. Olaru, Marcos Onofre, Iuliia Pavlova, Marie Rose Repond, Vassiliki Riga, Kasper Salin, Christophe Schnitzler, Damir Sekulic, Clemens Töpfer, Jana Vasickova, Günay Yıldızer, Viviana Zito, Peter Bentsen, Nigel Green, Peter Elsborg

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