Melanoma cells replicate through chemotherapy by reducing levels of key homologous recombination protein RAD51 and increasing expression of translesion synthesis DNA polymerase ζ by Liang Song, Ewan M. McNeil, Ann-Marie Ritchie, Katy R. Astell, Charlie Gourley, David W. Melton

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Mouse models of metastasis: progress and prospects by Laura Gómez-Cuadrado, Natasha Tracey, Ruoyu Ma, Binzhi Qian, Valerie G. Brunton

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Author Correction: A simple and robust real-time qPCR method for the detection of PIK3CA mutations by Virginia Alvarez-Garcia, Clare Bartos, Ieva Keraite, Urmi Trivedi, Paul M. Brennan, Maïwenn Kersaudy-Kerhoas, Karim Gharbi, Olga Oikonomidou, Nicholas R. Leslie

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Mondor's disease of the breast: A cutaneous thromboembolic manifestation of Covid-19? by Lorna Renshaw, J Michael Dixon, Julia Anderson, Arran K. Turnbull

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Towards a clinically-based common coordinate framework for the human gut cell atlas: the gut models by Albert Burger, Richard A. Baldock, David J. Adams, Shahida Din, Irene Papatheodorou, Michael Glinka, Bill Hill, Derek Houghton, Mehran Sharghi, Michael Wicks, Mark J. Arends

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Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation by Hemalvi Patani, Michael D. Rushton, Jonathan Higham, Saul A. Teijeiro, David Oxley, Pedro Cutillas, Duncan Sproul, Gabriella Ficz

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The NF-κB Nucleolar Stress Response Pathway by Hazel C. Thoms, Lesley A. Stark

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Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration by Alfonso Bolado-Carrancio, Oleksii S Rukhlenko, Elena Nikonova, Mikhail A Tsyganov, Anne Wheeler, Amaya Garcia-Munoz, Walter Kolch, Alex von Kriegsheim, Boris N Kholodenko

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Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics by Kamila Pawlicka, Umesh Kalathiya, Javier Alfaro

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Cancer burden and preparedness in fragile settings by Mhoira E F Leng, Maya Jane Bates, Liz Grant, Marie Fallon

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Cardiac Energetics Before, During, and After Anthracycline-Based Chemotherapy in Breast Cancer Patients Using 31P Magnetic Resonance Spectroscopy: A Pilot Study by Gillian Macnaught, Gillian Macnaught, Olga Oikonomidou, Olga Oikonomidou, Christopher T. Rodgers, William Clarke, Annette Cooper, Heather McVicars, Heather McVicars, Larry Hayward, Larry Hayward, Saeed Mirsadraee, Scott Semple, Scott Semple, Martin A. Denvir

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Evidence on the economic value of end-of-life and palliative care interventions: a narrative review of reviews by Xhyljeta Luta, Baptiste Ottino, Peter Hall, Joanna Bowden, Bee Wee, Joanne Droney, Julia Riley, Joachim Marti

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Temozolomide sensitivity of malignant glioma cell lines – a systematic review assessing consistencies between in vitro studies by Michael T. C. Poon, Morgan Bruce, Joanne E. Simpson, Cathal J. Hannan, Paul M. Brennan

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Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing miceResearch in context by Silvia Marino, Daniëlle de Ridder, Ryan T. Bishop, Nathalie Renema, Marco Ponzetti, Antonia Sophocleous, Mattia Capulli, Abdullah Aljeffery, Giovana Carrasco, Marianela Dalghi Gens, Asim Khogeer, Stuart H. Ralston, Jürg Gertsch, Francois Lamoureux, Dominique Heymann, Nadia Rucci, Aymen I. Idris

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Acetylation reprograms MITF target selectivity and residence time by Pakavarin Louphrasitthiphol, Alessia Loffreda, Vivian Pogenberg, Sarah Picaud, Alexander Schepsky, Hans Friedrichsen, Zhiqiang Zeng, Anahita Lashgari, Benjamin Thomas, E. Elizabeth Patton, Matthias Wilmanns, Panagis Filippakopoulos, Jean-Philippe Lambert, Eiríkur Steingrímsson, Davide Mazza, Colin R. Goding

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Variation in hospital cost trajectories at the end of life by age, multimorbidity and cancer type by Katharina Diernberger, Xhyljeta Luta, Joanna Bowden, Joanne Droney, Elizabeth Lemmon, Giovanni Tramonti, Bethany Shinkins, Ewan Gray, Joachim Marti, Peter S. Hall

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Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series by James McDonald, Judith Sayers, Stefan D. Anker, Jann Arends, Trude Rakel Balstad, Vickie Baracos, Leo Brown, Asta Bye, Olav Dajani, Ross Dolan, Marie T. Fallon, Eilidh Fraser, Christine Griel, Aleksandra Grzyb, Marianne Hjermstad, Mariam Jamal‐Hanjani, Gunnhild Jakobsen, Stein Kaasa, Donald McMillan, Matthew Maddocks, Iain Philips, Inger O. Ottestad, Kieran F. Reid, Mariana S. Sousa, Melanie R. Simpson, Ola Magne Vagnildhaug, Richard J. E. Skipworth, Tora S. Solheim, Barry J. A. Laird, the Cancer Cachexia Endpoints Working Group

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Crosstalk between NF-κB and Nucleoli in the Regulation of Cellular Homeostasis by Jingyu Chen, Lesley A. Stark

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Assessing the generalisability of radiomics features previously identified as predictive of radiation-induced sticky saliva and xerostomia by Thomas Berger, David J. Noble, Zhuolin Yang, Leila E.A. Shelley, Thomas McMullan, Amy Bates, Simon Thomas, Linda J. Carruthers, George Beckett, Aileen Duffton, Claire Paterson, Raj Jena, Duncan B. McLaren, Neil G. Burnet, William H. Nailon

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525 Preliminary safety, PK/PD and efficacy results from a first-in-human phase I/IIa clinical trial of BNT411, a systemic Toll-like receptor 7 agonist in patients with solid tumors... by Hendrik-Tobias Arkenau, Emiliano Calvo, Alain Mita, Young Kwang Chae, Devalingam Mahalingam, Ugur Sahin, Elena Garralda, Oezlem Tuereci, Vladimir Galvao, Stefan Symeonides, Maria Miguel, Hariz Hassan, Annette Baumhauer, Timo Völker, Marie-Cristine Kühnle, Roman Rösemann, Stefan Strobl