Can low-dose methotrexate reduce effusion-synovitis and symptoms in patients with mid- to late-stage knee osteoarthritis? Study protocol for a randomised, double-blind, and placebo... by Zhaohua Zhu, Qinghong Yu, Xiaomei Leng, Weiyu Han, Zhanguo Li, Cibo Huang, Jieruo Gu, Yi Zhao, Kang Wang, Tianwang Li, Yifang Mei, Jianhua Xu, Zhiyi Zhang, David Hunter, Flavia Cicuttini, Xiaofeng Zeng, Changhai Ding

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Early pre-radiographic structural pathology precedes the onset of accelerated knee osteoarthritis by Matthew S. Harkey, Julie E. Davis, Bing Lu, Lori Lyn Price, Robert J. Ward, James W. MacKay, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Ming Zhang, Jincheng Pang, Alina C. Stout, Timothy E. McAlindon, Jeffrey B. Driban

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Quantification of hip effusion-synovitis and its cross-sectional and longitudinal associations with hip pain, MRI findings and early radiographic hip OA by Harbeer Ahedi, Dawn Aitken, Leigh Blizzard, Flavia Cicuttini, Graeme Jones

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Changes and associations between synovial fluid and magnetic resonance imaging markers of osteoarthritis after high tibial osteotomy by Jenna M. Schulz, Trevor B. Birmingham, Holly T. Philpott, C. Thomas Appleton, Hayden F. Atkinson, J. Robert Giffin, Frank Beier

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Quadriceps strength is negatively associated with knee joint structural abnormalities—data from osteoarthritis initiative by Ze Gong, Jia Li, Zijun He, Shilin Li, Peihua Cao, Guangfeng Ruan, Yan Zhang, Qing Zeng, Rong Chen, Peng Zheng, Tao Fan, Yijin Zhao, Pengcheng Lu, Zhaohua Zhu, Guozhi Huang

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Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS) by Guoqi Cai, Graeme Jones, Flavia M. Cicuttini, Anita E. Wluka, Yuanyuan Wang, Catherine Hill, Helen Keen, Benny Antony, Xia Wang, Barbara de Graaff, Michael Thompson, Tania Winzenberg, Kathy Buttigieg, Dawn Aitken

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