Epidemiologic and Clinical Characteristics of Human Bocavirus Infection in Children with or without Acute Gastroenteritis in Acre, Northern Brazil by Fábyla D’ Tácia Brito Trindade, Endrya Socorro Foro Ramos, Patrícia Santos Lobo, Jedson Ferreira Cardoso, Edvaldo Tavares Penha Júnior, Delana Andreza Melo Bezerra, Mayara Annanda Oliveira Neves, Jorge Alberto Azevedo Andrade, Monica Cristina Moraes Silva, Joana D’Arc Pereira Mascarenhas, Sylvia Fátima Santos Guerra, Luana Silva Soares

“…Human bocavirus (HBoV) is an emerging virus detected around the world that may be associated with cases of acute gastroenteritis (AGE). …”
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The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis by Svetlana Chefer, Jurgen Seidel, Adam S. Cockrell, Boyd Yount, Jeffrey Solomon, Katie R. Hagen, David X. Liu, Louis M. Huzella, Mia R. Kumar, Elena Postnikova, J. Kyle Bohannon, Matthew G. Lackemeyer, Kurt Cooper, Ariel Endlich-Frazier, Heema Sharma, David Thomasson, Christopher Bartos, Philip J. Sayre, Amy Sims, Julie Dyall, Michael R. Holbrook, Peter B. Jahrling, Ralph S. Baric, Reed F. Johnson

“…The human sodium iodide symporter (hNIS), a SPECT and positron emission tomography reporter gene, was inserted into Middle East respiratory syndrome coronavirus (MERS-CoV), a recently emerged virus that can cause severe respiratory disease and death in afflicted humans to obtain a quantifiable and sensitive marker for viral replication to further MERS-CoV animal model development. …”
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An Effective Integrated Machine Learning Framework for Identifying Severity of Tomato Yellow Leaf Curl Virus and Their Experimental Validation by Nattanong Bupi, Vinoth Kumar Sangaraju, Le Thi Phan, Aamir Lal, Thuy Thi Bich Vo, Phuong Thi Ho, Muhammad Amir Qureshi, Marjia Tabassum, Sukchan Lee, Balachandran Manavalan

“…Plant virologists and plant breeding professionals can access the user-friendly online IML-TYLCVs web server at https://balalab-skku.org/IML-TYLCVs, which can guide them in developing new protection strategies for newly emerging viruses.…”
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Lyophilized Matrix Containing Ready-to-Use Primers and Probe Solution for Standardization of Real-Time PCR and RT-qPCR Diagnostics in Virology by Laurence Thirion, Audrey Dubot-Peres, Laura Pezzi, Iban Corcostegui, Mhammed Touinssi, Xavier de Lamballerie, Remi N. Charrel

“…They target two emerging viruses that are listed on the blueprint of the WHO as to be considered for preparedness and response actions: chikungunya virus (CHIKV) and Rift Valley fever phlebovirus (RVFV). …”
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Comprehensive Characterization of Serum MicroRNA Profile in Response to the Emerging Avian Influenza A (H7N9) Virus Infection in Humans by Zheng Zhu, Yuhua Qi, Aihua Ge, Yefei Zhu, Ke Xu, Hong Ji, Zhiyang Shi, Lunbiao Cui, Minghao Zhou

“…Although various detection procedures have been developed, the pathogenesis of this emerging virus in humans remains largely unknown. In this study, we characterized serum microRNA (miRNA) profile in response to H7N9 virus infection using TaqMan Low Density Arrays. …”
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Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2 by Simo Kitanovski, Gibran Horemheb-Rubio, Ortwin Adams, Barbara Gärtner, Thomas Lengauer, Daniel Hoffmann, Rolf Kaiser, Respiratory Virus Network

“…As RV is ubiquitous at higher prevalence than SARS-CoV-2 or other emerging respiratory viruses, it could reflect the efficacy of noninvasive measures better than such emerging viruses themselves with their unevenly spreading clusters.…”
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Zika Virus Infection of Sertoli Cells Alters Protein Expression Involved in Activated Immune and Antiviral Response Pathways, Carbohydrate Metabolism and Cardiovascular Disease by Mahamud-ur Rashid, Ying Lao, Victor Spicer, Kevin M. Coombs

“…Zika virus (ZIKV), a re-emerging virus, causes congenital brain abnormalities and Guillain–Barré syndrome. …”
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Mapping of Tilapia Lake Virus entry pathways with inhibitors reveals dependence on dynamin activity and cholesterol but not endosomal acidification by Reem Abu Rass, Japhette Esther Kembou-Ringert, Rachel Zamostiano, Avi Eldar, Marcelo Ehrlich, Eran Bacharach

“…Tilapia Lake Virus (TiLV) is an emerging virus lethal to tilapia, which threatens the global tilapia aquaculture with severe implications for food security. …”
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Lyophilized Matrix Containing Ready-to-Use Primers and Probe Solutions for Standardization of Real-Time PCR and RT-qPCR Diagnostics by Remi N Charrel, Laurence Thirion

“…They target two emerging viruses that are listed on the blueprint of the WHO to be considered for preparedness and response actions: <i>chikungunya virus</i> (CHIKV) and <i>Rift Valley fever phlebovirus</i> (RVFV). …”
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Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2. by Dong-Hoon Chung, Colleen B Jonsson, Nichole A Tower, Yong-Kyu Chu, Ergin Sahin, Jennifer E Golden, James W Noah, Chad E Schroeder, Julie B Sotsky, Melinda I Sosa, Daniel E Cramer, Sara N McKellip, Lynn Rasmussen, E Lucile White, Connie S Schmaljohn, Justin G Julander, Jeffrey M Smith, Claire Marie Filone, John H Connor, Yasuteru Sakurai, Robert A Davey

“…Alphaviruses present serious health threats as emerging and re-emerging viruses. Venezuelan equine encephalitis virus (VEEV), a New World alphavirus, can cause encephalitis in humans and horses, but there are no therapeutics for treatment. …”
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A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non... by Benoit Callendret, Jort Vellinga, Kerstin Wunderlich, Ariane Rodriguez, Robin Steigerwald, Ulrike Dirmeier, Cedric Cheminay, Ariane Volkmann, Trevor Brasel, Ricardo Carrion, Luis D Giavedoni, Jean L Patterson, Chad E Mire, Thomas W Geisbert, Jay W Hooper, Mo Weijtens, Jutta Hartkoorn-Pasma, Jerome Custers, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn

“…A good prophylactic vaccine should be able to provide protection to all known filovirus species and as an upside potentially protect from newly emerging virus strains. We investigated the immunogenicity and protection elicited by multivalent vaccines expressing glycoproteins (GP) from Ebola virus (EBOV), Sudan virus (SUDV), Taï Forest virus (TAFV) and Marburg virus (MARV). …”
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Molecular Tools to Identify and Characterize Malignant Catarrhal Fever Viruses (MCFV) of Ruminants and Captive <i>Artiodactyla</i> by Laura Bianchessi, Mara Silvia Rocchi, Madeleine Maley, Renata Piccinini, Lauretta Turin

“…This applies also to several gamma(γ)-herpesviruses, whose role as primary pathogen has been often neglected and, among these to newly emerged viruses or virus variants responsible for the development of Malignant Catarrhal Fever (MCF) or MCF-like disease. …”
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Circulation and seasonality of influenza viruses in different transmission zones in Africa by Marie Roseline Darnycka Belizaire, Anderson Kouabenan N’gattia, Bibata Wassonguema, Marcel Mbeko Simaleko, Emmanuel Nakoune, Clotaire Rafaï, Baidy Lô, Francisco Bolumar

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Shooting at a Moving Target—Effectiveness and Emerging Challenges for SARS-CoV-2 Vaccine Development by Franziska Günl, Angeles Mecate-Zambrano, Selina Rehländer, Saskia Hinse, Stephan Ludwig, Linda Brunotte

“…We focus on the real-world effectiveness and unexpected positive and negative side effects of the available vaccines and summarize the timeline of the applied adaptations to the recommended vaccination strategies in the light of emerging virus variants. Finally, we highlight upcoming strategies to improve the next generations of SARS-CoV-2 vaccines.…”
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Antibiotic treatment modulates protein components of cytotoxic outer membrane vesicles of multidrug-resistant clinical strain, Acinetobacter baumannii DU202 by Sung Ho Yun, Edmond Changkyun Park, Sang-Yeop Lee, Hayoung Lee, Chi-Won Choi, Yoon-Sun Yi, Hyun-Joo Ro, Je Chul Lee, Sangmi Jun, Hye-Yeon Kim, Gun-Hwa Kim, Seung Il Kim

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Multiple Lineages of Hantaviruses Harbored by the Iberian Mole (<i>Talpa occidentalis</i>) in Spain by Se Hun Gu, Marcos Miñarro, Carlos Feliu, Jean-Pierre Hugot, Naomi L. Forrester, Scott C. Weaver, Richard Yanagihara

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Immunization with SARS-CoV-2 Nucleocapsid protein triggers a pulmonary immune response in rats by Everidiene K. V. B. Silva, Camila G. Bomfim, Ana P. Barbosa, Paloma Noda, Irene L. Noronha, Bianca H. V. Fernandes, Rafael R. G. Machado, Edison L. Durigon, Sergio Catanozi, Letícia G. Rodrigues, Fabiana Pieroni, Sérgio G. Lima, Walcy R. Teodoro, Zelita A. J. Queiroz, Lizandre K. R. Silveira, Ives Charlie-Silva, Vera L. Capelozzi, Cristiane R. Guzzo, Camilla Fanelli

“…One of the employed techniques to produce vaccines against emerging viruses is the synthesis of recombinant proteins, which can be used as immunizing agents. …”
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Whole-genome sequencing and genetic diversity of severe fever with thrombocytopenia syndrome virus using multiplex PCR-based nanopore sequencing, Republic of Korea. by Jingyeong Lee, Kyungmin Park, Jongwoo Kim, Seung-Ho Lee, Geum-Young Lee, Seungchan Cho, Heung-Chul Kim, Terry A Klein, Jeong-Ah Kim, Jeewan Choi, Juwan Park, Dong-Hyun Song, Se Hun Gu, Hyeongseok Yun, Jung-Eun Kim, Daesang Lee, Gyeung Haeng Hur, Seong Tae Jeong, Il-Ung Hwang, Won-Keun Kim, Jin-Won Song

“…<h4>Background</h4>Whole-genome sequencing plays a critical role in the genomic epidemiology intended to improve understanding the spread of emerging viruses. Dabie bandavirus, causing severe fever with thrombocytopenia syndrome (SFTS), is a zoonotic tick-borne virus that poses a significant public health threat. …”
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Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. by Wei Zhang, Ben A Bailey-Elkin, Robert C M Knaap, Baldeep Khare, Tim J Dalebout, Garrett G Johnson, Puck B van Kasteren, Nigel J McLeish, Jun Gu, Wenguang He, Marjolein Kikkert, Brian L Mark, Sachdev S Sidhu

“…The recent Middle East respiratory syndrome coronavirus (MERS-CoV), Ebola and Zika virus outbreaks exemplify the continued threat of (re-)emerging viruses to human health, and our inability to rapidly develop effective therapeutic countermeasures. …”
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Mechanism of action and application of virocids in health care-associated viral infections by Babak Shahbaz, Mehdi Norouzi, Hamideh Tabatabai

“…Apart from frequently causing infections in the general community, many types of viruses are significant nosocomial pathogens that with emerging viruses has become a real issue in medical field. …”
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