Administration of AG490 decreases the senescence of umbilical cord-mesenchymal stem cells and promotes the cytotherapeutic effect in liver fibrosis by Chenhao Jiang, Huaxin Chen, Yinqian Kang, Xinyi He, Jianyang Huang, Tongyu Lu, Xin Sui, Haitian Chen, Jiaqi Xiao, Jiebin Zhang, Hanwen Zhang, Jun Zheng, Yang Yang, Jia Yao, Jianye Cai, Yingcai Zhang

Get full text

Translating prognostic quantification of c-MYC and BCL2 from tissue microarrays to whole slide images in diffuse large B-cell lymphoma using deep learning by Thomas E. Tavolara, M. Khalid Khan Niazi, Andrew L. Feldman, David L. Jaye, Christopher Flowers, Lee A.D. Cooper, Metin N. Gurcan

Get full text

Poor Cortical Venous Opacification on Baseline Computed Tomography Angiography Predicts Parenchymal Hemorrhage After Thrombectomy by Fouzi Bala, Nishita Singh, Bijoy K. Menon, Andrew M. Demchuk, Alexandre Y. Poppe, Ryan A. McTaggart, Raul G. Nogueira, Brian H. Buck, Mayank Goyal, Michael D. Hill, Mohammed A. Almekhlafi

Get full text

Late versus early response and depth of response are associated with improved outcomes in patients with newly diagnosed multiple myeloma enrolled in the TOURMALINE‐MM2 trial by Paul G. Richardson, Thierry Facon, Christopher P. Venner, Nizar J. Bahlis, Fritz Offner, Darrell White, Lionel Karlin, Lotfi Benboubker, Eric Voog, Sung‐Soo Yoon, Kenshi Suzuki, Hirohiko Shibayama, Xiaoquan Zhang, Miguel Villarreal, Philip Twumasi‐Ankrah, Richard Labotka, Robert M. Rifkin, Sagar Lonial, Shaji K. Kumar, S. Vincent Rajkumar, Philippe Moreau

Get full text

Longitudinal changes in diet quality and food intake before and after diabetes awareness in American adults: the Coronary Artery Risk Development in Young Adults (CARDIA) study by Guillermo E Umpierrez, Michael Bancks, Mercedes R Carnethon, Yuni Choi, David R Jacobs, EunSeok Cha, James M Shikany, Sandra B Dunbar, Melissa Spezia Faulkner, Jared Reis, Fengxia Yan

Get full text

Population pharmacokinetics of molnupiravir in adults with COVID‐19: Lack of clinically important exposure variation across individuals by Sébastien Bihorel, Youfang Cao, Akshita Chawla, Ruthie Birger, Brian M. Maas, Wei Gao, Stefan Roepcke, Susanne Sardella, Rebecca Humphrey, Sindhuri Kondragunta, Bhuvana Jayaraman, Monika Martinho, Wendy Painter, George Painter, Wayne Holman, Carisa De Anda, Michelle L. Brown, Matthew G. Johnson, Amanda Paschke, Matthew L. Rizk, Julie A. Stone

Get full text

Recombinant porcine factor VIII corrects thrombin generation in vitro in plasma from patients with congenital hemophilia A and inhibitors by Claude Négrier, Johannes Oldenburg, Gili Kenet, Shannon L. Meeks, Jean‐Claude Bordet, Jens Müller, Sandra Le Quellec, Peter L. Turecek, Nikola Tripkovic, Yesim Dargaud

Get full text

Urinary markers differentially associate with kidney inflammatory activity and chronicity measures in patients with lupus nephritis by Dominic Sinibaldi, Gabor G Illei, Wendy I White, S Sam Lim, Jason Cobb, Ahmad Akhgar, Lingmin Zeng, Alton B Farris, Monica Battle, David Chain, Jennifer A Cann

Get full text

Daily fosfomycin versus levofloxacin for complicated urinary tract infections by Nadine Rouphael, Patricia Winokur, Michael C. Keefer, Jessica Traenkner, Ana Drobeniuc, Yohei Doi, Sonal Munsiff, Vance G. Fowler, Scott Evans, Randolph E. Oler, Bonifride Tuyishimire, Marina Lee, Varduhi Ghazaryan, Henry F. Chambers

Get full text

Analysis of narrative assessments of internal medicine resident performance: are there differences associated with gender or race and ethnicity? by Robin Klein, Erin D. Snyder, Jennifer Koch, Anna Volerman, Sarah Alba-Nguyen, Katherine A. Julian, Vanessa Thompson, Nneka N. Ufere, Sherri-Ann M. Burnett-Bowie, Anshul Kumar, Bobbie Ann A. White, Yoon Soo Park, Kerri Palamara

Get full text

Has Authorship in the Decolonizing Global Health Movement Been Colonized? by Chris A. Rees, Gouri Rajesh, Hussein K. Manji, Catherine Shari, Rodrick Kisenge, Elizabeth M. Keating, Ikechukwu U. Ogbuanu, Kitiezo Aggrey Igunza, Richard Omore, Karim P. Manji

Get full text

Selection of an Optimal Recombinant Egyptian H9N2 Avian Influenza Vaccine Strain for Poultry with High Antigenicity and Safety by Se-Hee An, Seung-Eun Son, Jin-Ha Song, Seung-Min Hong, Chung-Young Lee, Nak-Hyung Lee, Young-Ju Jeong, Jun-Gu Choi, Youn-Jeong Lee, Hyun-Mi Kang, Kang-Seuk Choi, Hyuk-Joon Kwon

Get full text

Primary Skull Base Chondrosarcomas: A Systematic Review by Paolo Palmisciano, Ali S. Haider, Mohammadmahdi Sabahi, Chibueze D. Nwagwu, Othman Bin Alamer, Gianluca Scalia, Giuseppe E. Umana, Aaron A. Cohen-Gadol, Tarek Y. El Ahmadieh, Kenny Yu, Omar N. Pathmanaban

Get full text

Genetic and clinical variables act synergistically to impact neurodevelopmental outcomes in children with single ventricle heart disease by Thomas A. Miller, Edgar J. Hernandez, J. William Gaynor, Mark W. Russell, Jane W. Newburger, Wendy Chung, Elizabeth Goldmuntz, James F. Cnota, Sinai C. Zyblewski, William T. Mahle, Victor Zak, Chitra Ravishankar, Jonathan R. Kaltman, Brian W. McCrindle, Shanelle Clarke, Jodie K. Votava-Smith, Eric M. Graham, Mike Seed, Nancy Rudd, Daniel Bernstein, Teresa M. Lee, Mark Yandell, Martin Tristani-Firouzi

Get full text

Targeted Long-Read Bisulfite Sequencing Identifies Differences in the <i>TERT</i> Promoter Methylation Profiles between <i>TERT</i> Wild-Type and <i>TERT</i> Mutant Cancer Cells by Seungjae Lee, Ti-Cheng Chang, Patrick Schreiner, Yiping Fan, Neeraj Agarwal, Charles Owens, Reinhard Dummer, John M. Kirkwood, Raymond L. Barnhill, Dan Theodorescu, Gang Wu, Armita Bahrami

Get full text

Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism by Yi Kuang, Ohad Golan, Kristina Preusse, Brittany Cain, Collin J Christensen, Joseph Salomone, Ian Campbell, FearGod V Okwubido-Williams, Matthew R Hass, Zhenyu Yuan, Nathanel Eafergan, Kenneth H Moberg, Rhett A Kovall, Raphael Kopan, David Sprinzak, Brian Gebelein

Get full text

Plecanatide Improves Symptoms of Irritable Bowel Syndrome with Constipation: Results of an Integrated Efficacy and Safety Analysis of Two Phase 3 Trials by Brenner DM, Dorn SD, Fogel RP, Christie J, Laitman AP, Rosenberg J

“…Darren M Brenner,1 Spencer D Dorn,2 Ronald P Fogel,3 Jennifer Christie,4 Adam P Laitman,5 Jonathan Rosenberg6 1Internal Medicine-Gastroenterology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA; 2Division of Gastroenterology and Hepatology, UNC School of Medicine, Chapel Hill, NC, USA; 3Digestive Health Center of Michigan, Chesterfield, MI, USA; 4Emory University School of Medicine, Atlanta, GA, USA; 5Salix Pharmaceuticals, Bridgewater, NJ, USA; 6GI Alliance of Illinois, Gurnee, IL, USACorrespondence: Darren M Brenner, MD, FACG, AGAF, RFF, Northwestern Memorial Hospital/Arkes Family Pavilion, 676 N St Clair Street, Suite 1400, Chicago, IL, 60611, USA, Tel +1 312 695 8132, Fax +1 312 695 3999, Email Darren.Brenner@nm.orgPurpose: Patients with irritable bowel syndrome with constipation (IBS-C) experience abdominal pain with altered bowel movements. …”
Get full text

Adverse Effect of Circadian Rhythm Disorder on Reparative Angiogenesis in Hind Limb Ischemia by Kazuhito Tsuzuki, Yuuki Shimizu, Junya Suzuki, Zhongyue Pu, Shukuro Yamaguchi, Yusuke Fujikawa, Katsuhiro Kato, Koji Ohashi, Mikito Takefuji, Yasuko K. Bando, Noriyuki Ouchi, John W. Calvert, Rei Shibata, Toyoaki Murohara

Get full text

Third dose of an mRNA COVID-19 vaccine for patients with multiple myeloma by Marissa-Skye Goldwater, Samuel D. Stampfer, Bernard Sean Regidor, Sean Bujarski, Scott Jew, Haiming Chen, Ning Xu, Clara Kim, Susanna Kim, James R. Berenson

Get full text

Belatacept and carfilzomib-based treatment for antibody-mediated rejection in a sensitized nonhuman primate kidney transplantation model by Robin Schmitz, Miriam Manook, Zachary Fitch, Imran Anwar, Isabel DeLaura, Danae Olaso, Ashley Choi, Janghoon Yoon, Yeeun Bae, Mingqing Song, Alton B. Farris, Jean Kwun, Stuart Knechtle

Get full text