The first nationwide website survey of the availability and costs of medical and non-medical oocyte cryopreservation in Japan by Hiromitsu Shirasawa, Yukiyo Kumazawa, Wataru Sato, Takuya Iwasawa, Kazue Togashi, Natsuki Ono, Ayaka Fujishima, Kazumasa Takahashi, Eri Maeda, Yukihiro Terada

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Biphasic versus monophasic manual blood culture bottles for low-resource settings: an in-vitro study by Sien Ombelet, MD, Alessandra Natale, PhD, Jean-Baptiste Ronat, MSc, Thomas Kesteman, PhD, Olivier Vandenberg, ProfPhD, Jan Jacobs, ProfPhD, Liselotte Hardy, PhD

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Correlation Between Individual Child-Level Antibiotic Consumption and Antibiotic-Resistant Among Commensal Escherichia coli: Results from a Cohort of Children Aged 1–3 Years... by Khare S, Diwan V, Pathak A, Purohit MR, Stålsby Lundborg C

“…Shweta Khare,1,2 Vishal Diwan,1,3 Ashish Pathak,1,4 Manju Raj Purohit,1,5,* Cecilia Stålsby Lundborg1,* 1Health Systems and Policy (HSP): Medicines, Focusing Antibiotics, Department of Global Public Health, Karolinska Institutet, Stockholm, 171 77, Sweden; 2Department of Public Health and Environment, Ruxmaniben Deepchand Gardi Medical College, Ujjain, Madhya Pradesh, 456006, India; 3Division of Environmental Monitoring and Exposure Assessment (Water and Soil), ICMR—National Institute for Research in Environmental Health, Bhopal, Madhya Pradesh, 462030, India; 4Department of Pediatrics, Ruxmaniben Deepchand Gardi Medical College, Ujjain, Madhya Pradesh, 456006, India; 5Department of Pathology, Ruxmaniben Deepchand Gardi Medical College, Ujjain, Madhya Pradesh, 456006, India*These authors contributed equally to this workCorrespondence: Shweta Khare, Health Systems and Policy (HSP): Medicines, Focusing Antibiotics, Department of Global Public Health, Karolinska Institutet, Stockholm, 171 77, Sweden, Tel +91 9893986241, Email shweta.khare@ki.seBackground: The global expansion of antibiotic-resistant bacteria is a serious concern and is increasing worldwide in both pathogenic and commensal bacteria. …”
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Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies by Yan Li, Chen Xu, Bing Wang, Fujiang Xu, Fahan Ma, Yuanyuan Qu, Dongxian Jiang, Kai Li, Jinwen Feng, Sha Tian, Xiaohui Wu, Yunzhi Wang, Yang Liu, Zhaoyu Qin, Yalan Liu, Jing Qin, Qi Song, Xiaolei Zhang, Akesu Sujie, Jie Huang, Tianshu Liu, Kuntang Shen, Jian-Yuan Zhao, Yingyong Hou, Chen Ding

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Comparison of metabolic syndrome prevalence and characteristics using five different definitions in China: a population-based retrospective study by Keli Ma, Haiyang Liu, Leilei Guo, Jinlong Li, Yunxiao Lei, Xiaoping Li, Lu Sun, Liu Yang, Ting Yuan, Congzhi Wang, Dongmei Zhang, Jing Li, Mingming Liu, Ying Hua, Lin Zhang

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High-resolution mass spectrometry identifies delayed biomarkers for improved precision in acetaminophen/paracetamol human biomonitoring by Eva Gorrochategui, Marc Le Vee, Habiba Selmi, Anne Gérard, Jade Chaker, Annette M. Krais, Christian Lindh, Olivier Fardel, Cécile Chevrier, Pierre Le Cann, Gary W. Miller, Robert Barouki, Bernard Jégou, Thomas Gicquel, David M. Kristensen, Arthur David

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التمكين البيئي للمرأة الريفية في محافظة اللاذقية "دراسة تحليلية تقويمية لبرامج مشروع عين التينة" by ريمون المعلولي, أحلام ياسين

“…So, the study, pointed out a significant difference between the sample mean and the assumed average, which represents the average level of the activities proposed to be implemented by the Centre in the domain of education, rehabilitation and training, on safety, environmental health and beauty. Therefore these programs for rural women enabling must take into consideration plans and strategies to be pursued in empowering rural women, environmentally and educationally, in order to harsen the environmental problems faced by women, and to contribute in environment maintenance and in preventing  new problems. …”
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The effect of nicotine-containing products and fetal sex on placenta-associated circulating midpregnancy biomarkers by Birgitte Kordt Sundet, Ina Kreyberg, Anne Cathrine Staff, Karin Cecilie Lødrup Carlsen, Karen Eline Stensby Bains, Jens Petter Berg, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Christine Monceyron Jonassen, Live Solveig Nordhagen, Björn Nordlund, Eva Maria Rehbinder, Knut Rudi, Corina Silvia Rueegg, Katrine Dønvold Sjøborg, Håvard Ove Skjerven, Cilla Söderhäll, Riyas Vettukattil, Meryam Sugulle

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Co-exposure to polycyclic aromatic hydrocarbons and metals, four common polymorphisms in microRNA genes, and their gene-environment interactions: Influences on oxidative damage lev... by Yunling Xie, Tao Lin, Ming Yang, Zhaorui Zhang, Na Deng, Mengqi Tang, Yongmei Xiao, Huan Guo, Qifei Deng

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Exploring RNA methylation as a promising biomarker for assessing sublethal effects of fipronil on honeybees (Apis mellifera L.) by Man Fan, Suzhen Qi, Nan Jiang, Qiangqiang Li, Liuwei Zhao, Liming Wu, Shaokang Huang, Miao Wang

“…Honeybees play a crucial role as pollinators for crops and are regarded as sensitive bioindicators of environmental health. The widespread use of pesticides poses a severe threat to honeybee survival. …”
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Associations of urinary non-persistent endocrine disrupting chemical biomarkers with early-to-mid pregnancy plasma sex-steroid and thyroid hormones by Brad A. Ryva, Diana C. Pacyga, Kaitlyn Y. Anderson, Antonia M. Calafat, Jason Whalen, Max T. Aung, Joseph C. Gardiner, Joseph M. Braun, Susan L. Schantz, Rita S. Strakovsky

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Evaluation of <i>Magonia pubescens</i> A. St.-Hill. Roots Extract against Phytopathogens: Searching for Eco-Friendly Crop Protection Products by Acácio R. A. Moraes, Samuel R. Sabina, Daniela G. Expósito, Cristina Giménez, Guacimara Espinel, Grasiely F. Sousa, Lucienir P. Duarte, Ignacio A. Jiménez, Raimundo Cabrera, Isabel L. Bazzocchi

“…Botanical biopesticides have emerged as sustainable and eco-friendly alternatives to synthetic pesticides, whose indiscriminate use leads to several drawbacks to human and environmental health. To the best of our knowledge, there have been no reports on <i>M. pubescens</i>’ bioactivity on phytopathogens affecting crops as a potential fungicide or antifeedant. …”
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Age-related differences in the survival benefit of the administration of antithrombin, recombinant human thrombomodulin, or their combination in sepsis by Takeshi Wada, Kazuma Yamakawa, Daijiro Kabata, Toshikazu Abe, Hiroshi Ogura, Atsushi Shiraishi, Daizoh Saitoh, Shigeki Kushimoto, Seitaro Fujishima, Toshihiko Mayumi, Toru Hifumi, Yasukazu Shiino, Taka-aki Nakada, Takehiko Tarui, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi, Satoshi Gando

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What Kind of Intervention Is Effective for Improving Subjective Well-Being Among Workers? A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Asuka Sakuraya, Kotaro Imamura, Kazuhiro Watanabe, Yumi Asai, Emiko Ando, Hisashi Eguchi, Norimitsu Nishida, Yuka Kobayashi, Hideaki Arima, Mai Iwanaga, Yasumasa Otsuka, Natsu Sasaki, Akiomi Inoue, Reiko Inoue, Kanami Tsuno, Ayako Hino, Akihito Shimazu, Akizumi Tsutsumi, Norito Kawakami

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Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses by Ana Lucia Espinosa Dice, Rebecca B. Lawn, Andrew Ratanatharathorn, Andrea L. Roberts, Christy A. Denckla, Ariel H. Kim, Pedro A. de la Rosa, Yiwen Zhu, Tyler J. VanderWeele, Karestan C. Koenen

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The Prevalence and Risk Factors of Trichosporonosis at King Abdulaziz University Hospital by Alboloshi GJ, Jiman-Fatani AA, Attallah D, Mokhtar JA, Al-Abdullah NA, Alkuwaity K, Kaki R, Al-Rabia MW, Alfadil A, Ibrahem K, Teklemariam AD, Harakeh S

“…Ghassan J Alboloshi,1 Asif A Jiman-Fatani,2,3 Dalya Attallah,3 Jawahir A Mokhtar,2– 4 Nabeela Abdullah Al-Abdullah,5,6 Khalil Alkuwaity,4,7 Reham Kaki,6,8 Mohammed W Al-Rabia,2 Abdelbagi Alfadil,2,9 Karem Ibrahem,2 Addisu D Teklemariam,10,11 Steve Harakeh12,13 1Department of Medical Laboratories, King Abdullah Medical Complex Jeddah, Ministry of Health, Jeddah, Saudi Arabia; 2Department of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 3Department of Clinical and Molecular Microbiology Laboratory, King Abdulaziz University Hospital, Jeddah, Saudi Arabia; 4Vaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; 5Department of Public Health, College of Nursing, King Abdulaziz University, Jeddah, Saudi Arabia; 6Department of Infection Control and Environmental Health, King Abdulaziz University Hospital, Jeddah, Saudi Arabia; 7Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; 8Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 9Center of Research Excellence for Drug Research and Pharmaceutical Industries, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 10Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 11Department of MIVP, College of Veterinary Medicine and Agriculture, Addis Ababa University, Addis Ababa, Ethiopia; 12King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; 13Yousef Abdul Latif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi ArabiaCorrespondence: Abdelbagi Alfadil, Department of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, P.O. …”
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Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes by Kendall Higgins, Bret A. Moore, Zorana Berberovic, Hibret A. Adissu, Mohammad Eskandarian, Ann M. Flenniken, Andy Shao, Denise M. Imai, Dave Clary, Louise Lanoue, Susan Newbigging, Lauryl M. J. Nutter, David J. Adams, Fatima Bosch, Robert E. Braun, Steve D. M. Brown, Mary E. Dickinson, Michael Dobbie, Paul Flicek, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D. Heaney, Yann Herault, Martin Hrabe de Angelis, Hsian-Jean Genie Chin, Fabio Mammano, Chuan Qin, Toshihiko Shiroishi, Radislav Sedlacek, J.-K. Seong, Ying Xu, The IMPC Consortium, K. C. Kent Lloyd, Colin McKerlie, Ala Moshiri

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Single-cell RNA sequencing reveals the role of mitochondrial dysfunction in the cardiogenic toxicity of perfluorooctane sulfonate in human embryonic stem cells by Min Qiu, Jing Chen, Mingqin Liu, Zhiqiang Nie, Miaola Ke, Guanghui Dong, Haishan Zhao, Chengbin Zhou, Haiyan Zeng, Biaochuan He, Jimei Chen, Jian Zhuang, Xiaohong Li, Yanqiu Ou

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Prescribing Patterns of Antibiotics According to the WHO AWaRe Classification during the COVID-19 Pandemic at a Teaching Hospital in Lusaka, Zambia: Implications for Strengthening... by Steward Mudenda, Eustus Nsofu, Patience Chisha, Victor Daka, Billy Chabalenge, Webrod Mufwambi, Henson Kainga, Manal H.G. Kanaan, Ruth L. Mfune, Florence Mwaba, Mildred Zulu, Rabecca Tembo, Wizaso Mwasinga, Kennedy Chishimba, Grace Mwikuma, Ngula Monde, Mulemba Samutela, Harriet K. Chiyangi, Shafiq Mohamed, Scott K. Matafwali

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The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression by Meng Xu, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P. Hoefig, Christine Hohn, Florian Giesert, Yinhu Wang, Wenliang Pan, Natalia Ziętara, Tobias Straub, Regina Feederle, Carolin Daniel, Barbara Adler, Julian König, Stefan Feske, George C. Tsokos, Wolfgang Wurst, Henning Urlaub, Michael Sattler, Jan Kisielow, F. Gregory Wulczyn, Marcin Łyszkiewicz, Vigo Heissmeyer

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