The Allergen Immunotherapy Adverse Events Registry: Setup & methodology of a European Academy of Allergy and Clinical Immunology taskforce project by Julijana Asllani, Dimitrios Mitsias, George Konstantinou, Alfred Priftanji, Mehmet Hoxha, Gerta Sinani, George Christoff, Dimitrov Zlatko, Michael Makris, Xenofon Aggelidis, Asja Stipic, Sanja Popovic‐Grle, Diana Deleanu, Vesna Tomic‐Spiric, Aleksandra Plavsic, Dilsad Mungan, Mitja Kosnik, Todor A. Popov, Nikolaos G. Papadopoulos, Moises Calderon, ADER study group

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A survey study on antibiotic prescription practices for acute asthma exacerbations: An European academy of allergy and clinical immunology task force report by Anne‐Lotte Redel, Wojciech Feleszko, Alessandra Arcolaci, Francesca Cefaloni, Marina Atanaskovic‐Markovic, Gert‐Jan Braunstahl, Cristina Boccabella, Matteo Bonini, Aspasia Karavelia, Eefje Louwers, Norbert Mülleneisen, Liam O'Mahony, Laura Pini, Anna Rapiejko, Esmeralda Shehu, Milena Sokolowska, Eva Untersmayr, Gerdien Tramper‐Stranders, EAACI Task Force on Conscious and Rational use of Antibiotics in Allergic Diseases

“…The survey was distributed among European academy of allergy and clinical immunology (EAACI) members by mass emailing and through regional/national societies in the Netherlands, Italy, Greece, and Poland. …”
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Adverse events in children and adolescents undergoing allergen immunotherapy for respiratory allergies—Report from the Allergen Immunotherapy Adverse Events Registry (ADER), a European Academy of Allergy and Clinical Immunology taskforce by Julijana Asllani, Dimitrios Mitsias, George Konstantinou, Eris Mesonjesi, Fatmira Xhixha, Esmeralda Shehu, George Christoff, Katia Noleva, Michael Makris, Xenofon Aggelidis, Mirjana Turkalj, Erceg Damir, Ioana Agache, Vesna Tomic‐Spiric, Rajica Stosovic, Zeynep Misirligil, Mitja Kosnik, Todor A. Popov, Moises Calderon, Nikolaos G. Papadopoulos, ADER study group

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Density-equalizing mapping and scientometric benchmarking of European allergy research by Fischer Tanja C, Vitzthum Karin, Al-Mutawakel Khaled, Shami Awfa, Sakr Mohannad, Quarcoo David, Scutaru Cristian, Zuberbier Torsten, Groneberg-Kloft Beatrix

“…Three different meetings of the European Academy of Allergy and Clinical Immunology were analysed for contributions and an increase in both the amount of research and networks was found.…”
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Safety of specific immunotherapy using an ultra-rush induction regimen in bee and wasp allergy by Andrzej Bożek, Krzysztof Kołodziejczyk

“…Patients were selected based on the criteria established by EAACI (European Academy of Allergy and Clinical Immunology) recommendations. Adverse reactions during the ultra-rush immunotherapy were measured, documented and classified according to the criteria of Mueller. …”
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Effects of climatic changes and urban air pollution on the rising trends of respiratory allergy and asthma by D'Amato Gennaro

“…</p> <p>Scientific societies such as the European Academy of Allergy and Clinical Immunology, European Respiratory Society and the World Allergy Organization have set up committees and task forces to produce documents to focalize attention on this topic, calling for prevention measures.…”
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EAACI position statement on asthma exacerbations and severe asthma. by Custovic, A, Johnston, S, Pavord, I, Gaga, M, Fabbri, L, Bel, E, Le Souëf, P, Lötvall, J, Demoly, P, Akdis, C, Ryan, D, Mäkelä, M, Martinez, F, Holloway, J, Saglani, S, O'Byrne, P, Papi, A, Sergejeva, S, Magnan, A, Del Giacco, S, Kalayci, O, Hamelmann, E, Papadopoulos, N

“…This position paper, from the European Academy of Allergy and Clinical Immunology, highlights the shortcomings of current treatment guidelines for patients suffering from frequent asthma exacerbations and those with difficult-to-treat asthma and severe treatment-resistant asthma. …”

Immunotherapy in patients with the first type of hypersensitivity to Hymenoptera venoms by Jovanović Dragana, Perić-Popadić Aleksandra

“…The latest European Academy of Allergy and Clinical Immunology (EAACI) guidelines provide evidence-based recommendations for the use of VIT. …”
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The Utility of Nasal Challenges to Phenotype Asthma Patients by Guillermo Bentabol-Ramos, Rocio Saenz de Santa Maria-Garcia, Monica Vidal-Diaz, Ibon Eguiluz-Gracia, Almudena Testera-Montes

“…Of note, a recent document by the European Academy of Allergy and Clinical Immunology proposes the use of nasal allergen challenge to confirm the diagnosis of allergic asthma. …”
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Correlation of the combined symptom and medication score with quality of life, symptom severity and symptom control in allergic rhinoconjunctivitis by Binoy Palathumpattu, Ursula Pieper‐Fürst, Cengizhan Acikel, Hacer Sahin, Silke Allekotte, Jaswinder Singh, Mark Hess, Angelika Sager, Thomas Müller, Ralph Mösges

“…Abstract Background The European Academy of Allergy and Clinical Immunology recommended the Combined Symptom and Medication Score (CSMS) as primary endpoint in clinical trials on allergen‐specific immunotherapy (AIT) in allergic rhinoconjunctivitis. …”
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Real-Life Utility of Basophil Activation Test in the Diagnosis of Immediate Hypersensitivity Drug Reactions by Dimitra Koumaki, Stamatios Gregoriou, Georgios Evangelou, Alexander Katoulis, Marios Papadakis, Sabine Elke Krueger-Krasagakis, Aikaterini Doxastaki, Dimitrios Mylonakis, Konstantinos Krasagakis

“…The allergological evaluation was carried out in accordance with European Academy of Allergy and Clinical Immunology (EAACI) guidance. All patients underwent BAT using the activation marker CD63. …”
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Adverse reactions in venom immunotherapy protocols: conventional versus ultra-rush by Ali Selcuk, Abdullah Baysan, Sait Yesillik, Fevzi Demirel, Ozgur Kartal, Mustafa Gulec, Ugur Musabak, Osman Sener

“…Patients were diagnosed and selected for VIT according to the criteria established by the European Academy of Allergy and Clinical Immunology. The severity of systemic reactions was evaluated according to the criteria of Mueller.Results Build-up phases were tolerated in 66.2% (n = 47) without any reaction. …”
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Diagnosis, Management and Prescription Practices of Adrenaline in Children with Food-Induced Anaphylaxis: Audit in a Specialized Pediatric Allergy Department by Konstantinos Vamvakaris, Alkmini Koumpoura, Maria Farmaki, John Lakoumentas, Maria Pasioti, Nikolaos Papadopoulos, Paraskevi Xepapadaki

“…This audit evaluates the degree of compliance with the European Academy of Allergy and Clinical Immunology guidelines for the diagnosis and treatment of anaphylaxis in a pediatric Allergy Department. …”
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Food allergy outside the eight big foods in Europe: A systematic review and meta‐analysis by Giulia C. I. Spolidoro, Sungkutu Nyassi, Daniil Lisik, Athina Ioannidou, Mohamed Mustafa Ali, Yohannes Tesfaye Amera, Graciela Rovner, Ekaterina Khaleva, Carina Venter, Ronald vanRee, Margitta Worm, Berber Vlieg‐Boerstra, Aziz Sheikh, Antonella Muraro, Graham Roberts, Bright I. Nwaru

“…Abstract Background The 2014 estimates of prevalence of food allergy (FA) in Europe published by the European Academy of Allergy and Clinical Immunology included only the eight so‐called big foods (cow's milk/egg/wheat/soy/peanut/tree nuts/fish/shellfish). …”
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Differential diagnosis between urticarial vasculitis and chronic spontaneous urticaria: An international Delphi survey by Karoline Krause, Hanna Bonnekoh, Jannis Jelden‐Thurm, Riccardo Asero, Ana Maria Gimenez‐Arnau, José C. Cardoso, Clive Grattan, Emek Kocatürk, Undine Lippert, Marcus Maurer, Martin Metz, Petra Staubach, Margarida Goncalo, Pavel Kolkhir

“…Methods Thirteen experts experienced in UV research participated in a Delphi survey of European Academy of Allergy and Clinical Immunology taskforce. This Delphi survey involved three rounds of anonymous responses to n = 32 questions with the aim to aggregate the experts' opinions and to achieve consensus. …”
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Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation by Versi, Ali, Ivan, Fransiskus Xaverius, Abdel-Aziz, Mahmoud I., Bates, Stewart, Riley, John, Baribaud, Frederic, Kermani, Nazanin Zounemat, Montuschi, Paolo, Dahlen, Sven-Erik, Djukanovic, Ratko, Sterk, Peter, Maitland-Van Der Zee, Anke H., Chotirmall, Sanjay Haresh, Howarth, Peter, Adcock, Ian M., Chung, Kian Fan

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Comparison of recent anaphylaxis diagnostic criteria in real life: Can more patients be diagnosed as having anaphylaxis? by Osman Ozan Yeğit, MD, Ayşe Feyza Aslan, MD, Raif Coşkun, MD, Pelin Karadağ, MD, İlkim Deniz Toprak, MD, Ali Can, MD, Nida Öztop, MD, Semra Demir, MD, Derya Ünal, MD, Müge Olgaç, MD, Aslı Gelincik, MD

“…Introduction: In 2020, World Allergy Organization (WAO) updated their diagnostic criteria for anaphylaxis, which differed as a result from the National Institute of Allergy and Infectious Diseases/Food Allergy and Anaphylaxis Network (NIAID/FAAN) criteria which were still used in the 2021 update of the European Academy of Allergy and Clinical Immunology (EAACI) anaphylaxis guideline. …”
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Consensus on diagnosis and management of Hereditary Angioedema in the Middle East: A Delphi initiative by Marcus Maurer, MD, Mohamed Abuzakouk, MD, PhD, Mona Al-Ahmad, MD, Waleed Al-Herz, MD, Hassan Alrayes, MD, Salem Al-Tamemi, MD, Rand Arnaout, MD, Hend Binghadeer, MD, Ravi Gutta, MD, Carla Irani, MD, Hassan Mobayed, MD, Iman Nasr, MD, Hiba Shendi, MD, Fares Zaitoun, MD, FACAAI

“…The global World Allergy Organization (WAO)/European Academy of Allergy and Clinical Immunology (EAACI) International guideline for HAE management is comprehensive, but the implementation of this guideline may require regional adaptation considering the diversity in disease awareness, type of medical care systems, and access to diagnostics and treatment. …”
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Clinical benefits with 300 IR HDM SLIT tablet in Europeans with house dust mite allergic rhinitis: Post hoc analysis of a large phase 3 trial by Oliver Pfaar, MD, PhD, Frédéric De BLAY, MD, Giorgio Walter Canonica, MD, Thomas B. Casale, MD, PhD, Philippe Gevaert, MD, PhD, Peter W. Hellings, MD, PhD, Krzysztof Kowal, MD, PhD, Giovanni Passalacqua, MD, Miguel Tortajada-Girbés, MD, PhD, Carmen Vidal, MD, PhD, Margitta Worm, MD, PhD, Farah Bahbah, MD, Pascal Demoly, MD, PhD

“…The treatment effect in European adults and adolescents was notably assessed through the European Academy of Allergy and Clinical Immunology (EAACI)-recommended combined symptom and medication score (CSMS0-6, pre-defined endpoint) and the total combined rhinitis score (TCRS0-24, post hoc endpoint, also balanced) during the primary evaluation period (4 weeks at the end of treatment period) using analysis of covariance (ANCOVA). …”
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GUIMIT 2019, Mexican Guideline on Immunotherapy. Guideline on the diagnosis of IgE-mediated allergic disease and immunotherapy following the ADAPTE approach by Désirée Larenas-Linnemann, Jorge A. Luna-Pech, Noel Rodríguez-Pérez, Mónica Rodríguez-González, Alfredo Arias-Cruz, María Virginia Blandón-Vijil, María del Carmen Costa-Domínguez, Blanca E. Del Río-Navarro, Alan Estrada-Cardona, Elsy Maureen Navarrete-Rodríguez, José Antonio Ortega-Martell, César Fireth Pozo-Beltrán, Herson Brito-Díaz, María del Rosario Canseco-Raymundo, Enrique Emanuel Castelán-Chávez, Margarita Gabriela Domínguez-Silva, Alberto José Escalante-Domínguez, José Luis Gálvez-Romero, María Guadalupe García-Reyes, Javier Gómez-Vera, Sandra Nora González-Díaz, María Gracias Belinda Guerrero-Núñez, Dante Hernández-Colín, Alejandra Macías-Weinmann, David Alejandro Mendoza-Hernández, Néstor Alejandro Meneses-Sánchez, María Dolores Mogica-Martínez, Carol Vivian Moncayo-Coello, Manuel Montiel-Herrera, Patricia O’Farril-Romanillos, Ernesto Onuma-Takane, Margarita Ortega-Cisneros, Lorena Rangel-Garza, Héctor Stone-Aguilar, Carlos Torres-Lozano, Edna Venegas-Montoya, Guillermo Wakida-Kusunoki, Carlos Macouzet-Sánchez, Armando Partida-Gaytán, Aída Inés López-García, Ana Paola Macías-Robles, María de Jesús Ambriz-Moreno, Amyra Ali Azamar-Jácome, Carlos Báez-Loyola, Claudia Yusdivia Beltrán-De Paz, Chrystopherson Caballero-López, Juan Carlos Fernández de Córdova-Aguirre, Roberto Fernández-Soto, José Santos Lozano-Sáenz, José Joel Oyoqui-Flores, Roberto Osorio-Escamilla, Fernando Ramírez, Daniela Rivero-Yeverino, María del Socorro Orozco-Martínez, María Isabel Rojo-Gutiérrez, Eric Martínez, Miguel Alejandro Medina-Ávalos

“…Method: With nationwide groups of allergists participating, including delegates from postgraduate training-programs in Allergy/Immunology-forming, the guideline document was developed according to the ADAPTE methodology: the immunotherapy guidelines from European Academy of Allergy and Clinical Immunology, German Society for Allergology and Clinical Immunology, The American Academy of Allergy, Asthma and Immunology and American College of Allergy, Asthma, and Immunology were selected as mother guidelines, as they received the highest AGREE-II score among international guidelines available; their evidence conforms the scientific basis for this document. …”
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