Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosa. by Hiromi Sato, Meredith L Hunt, Joshua J Weiner, Andrew T Hansen, Dara W Frank

“…Three of these regulatory mutants, in which the linker was inserted in the N-terminal globular domain, were competent for the translocation of a cytotoxin, ExoU, into eukaryotic host cells. We also isolated strains expressing a delayed-toxicity phenotype, which secrete translocators slowly despite the normal level of effector secretion. …”
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The Base Excision Repair Pathway in the Nematode Caenorhabditis elegans by Noha Elsakrmy, Qiu-Mei Zhang-Akiyama, Dindial Ramotar

“…In addition, the animal possesses two AP endonucleases belonging to the exonuclease-3 and endonuclease IV families and in C. elegans these enzymes are called EXO-3 and APN-1, respectively. In mammalian cells, the DNA polymerase, Pol beta, that is required to reinsert the correct bases for DNA repair synthesis is not found in the genome of C. elegans and the evidence indicates that this role could be substituted by DNA polymerase theta (POLQ), which is known to perform a function in the microhomology-mediated end-joining pathway in human cells. …”
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Anisotropic stars via embedding approach in Brans–Dicke gravity by S. K. Maurya, Ksh. Newton Singh, M. Govender, Abdelghani Errehymy, Francisco Tello-Ortiz

“…We also show that our solutions describe compact objects such as PSR J1903+327; Cen X-3; EXO 1785-248 and LMC X-4 to an excellent approximation. …”
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Multiple hits for the association of uterine fibroids on human chromosome 1q43. by Brahim Aissani, Howard Wiener, Kui Zhang

“…In particular, genes encoding factors suspected (cytosolic FH) or known (EXO1 - exonuclease 1) to be involved in DNA mismatch repair emerged as candidate susceptibility genes whereas those acting in the autophagy/apoptosis (MAP1LC3C - microtubule-associated protein) or signal transduction (RGS7 - Regulator of G-protein and PLD5- Phospoholipase D) appeared to affect tumor growth. …”
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Exhibition activity as a pedagogical factor in the formation of the personality of culture by Nosenko Anna, Tverdokhlibova Yanina, Velychko Dmytro

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Identifying diagnostic markers and constructing a prognostic model for small-cell lung cancer based on blood exosome-related genes and machine-learning methods by Kun Zhang, Chaoguo Zhang, Ke Wang, Xiuli Teng, Mingwei Chen

“…Therefore, this study aimed to screen for diagnostic markers of blood exosomes in SCLC patients and to build a prognostic model.MethodsWe identified blood exosome differentially expressed (DE) RNAs in the exoRBase cohort and identified feature RNAs by the LASSO, Random Forest, and SVM-REF three algorithms. …”
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Theoretical Insight into the Reaction Mechanism and Kinetics for the Criegee Intermediate of <i>anti</i>-PhCHOO with SO₂ by Benni Du, Weichao Zhang

“…Two different five-membered ring adducts, viz., <i>endo</i> PhCHOOS(O)O (IM1) and <i>exo</i> PhCHOOS(O)O (IM2) have been found in the entrance of reaction channels. …”
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circRNA, a novel diagnostic biomarker for coronary heart disease by Xiao Tong, Xinyi Zhao, Xuan Dang, Yan Kou, Junjie Kou

“…ObjectiveThis study aimed to identify the potential diagnostic biomarkers of coronary heart disease (CHD) from exosome-derived circRNA.MethodsThe microarray data of circRNA derived from the exosomes of patients with CHD and mRNA in acute myocardial infarction was retrieved from exoRBase website and GEO database (GSE61144), respectively, to identify the differentially expressed genes (DEGs). …”
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Enhanced Enzymatic Degradability of Livestock Blood Pretreated with Ultrasonic Technique by Mi-Jin Jeon, Yong-Woo Jeon

“…As a result of hydrolyzing ultrasonically pretreated blood by mixing exo- and endo-type proteolytic enzymes, the optimal combination was a mixture of Savinase^® 1% and Flavourzyme^® 1%. …”
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Validation of a Novel Double Control Quantitative Copy Number PCR Method to Quantify Off-Target Transgene Integration after CRISPR-Induced DNA Modification by Brit-Maren Michaud Schjeide, Maren Schenke, Bettina Seeger, Gerhard Paul Püschel

“…This can possibly be explained by the lower bundled relative gene expression of a number of double-strand repair genes (<i>BRCA1</i>, <i>DNA2</i>, <i>EXO1</i>, <i>MCPH1</i>, <i>MRE11</i>, and <i>RAD51</i>) in SiMa clones than in iPSC clones. …”
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Molecular Interactions of β-(1→3)-Glucans with Their Receptors by Laurent Legentil, Franck Paris, Caroline Ballet, Sophie Trouvelot, Xavier Daire, Vaclav Vetvicka, Vincent Ferrières

“…β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. …”
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Bioactive principles from Cordyceps sinensis: A potent food supplement – A review by M.G. Shashidhar, P. Giridhar, K. Udaya Sankar, B. Manohar

“…The bioactive principles are nucleosides, exo-polysaccharides, sterols and, proteins, among others. …”
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A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives by Vučković Gordana, Tanasković Slađana B., Antonijević-Nikolić Mirjana, Živković-Radovanović Vukosava, Gojgić-Cvijović Gordana

“…It is assumed that all complexes are binuclear with an exo coordination mode of the octaazamacrocyclic pendant ligand in the boat conformation. …”
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BMSC-Derived Exosomes Alleviate Sepsis-Associated Acute Respiratory Distress Syndrome by Activating the Nrf2 Pathway to Reverse Mitochondrial Dysfunction by Zhenzhen Li, Beijie Zheng, Chenchen Liu, Xiang Zhao, Yupeng Zhao, Xiangrui Wang, Lei Hou, Zhongwei Yang

“…Recent evidence has proved that bone mesenchymal stem cell-derived exosomes (BMSC-exos) can effectively reduce sepsis-induced ARDS. …”
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Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease by Catarina Perdigão, Mariana A. Barata, Margarida N. Araújo, Farzaneh S. Mirfakhar, Jorge Castanheira, Cláudia Guimas Almeida

“…We conclude that in eFAD and LOAD, the earliest synaptic dysfunctions are characterized by disruptions of the presynaptic vesicle exo- and endocytosis and of postsynaptic glutamate receptor endocytosis. …”
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Hospitalized elder abuse in Iran: a qualitative study by Zeinab Naderi, Sakineh Gholamzadeh, Ladan Zarshenas, Abbas Ebadi

“…Results Based on the analysis of the interview data, four main categories were extracted and classified as Micro-level, Meso-level, Exo-level, and Macro-level issues. Conclusion Hospitalized elder abuse is a multi-dimensional phenomenon caused by personal and professional factors as well as issues related to the inadequate physical environment and organizational structure. …”
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Slowing down decay: biological clocks in personalized medicine by Clémence Pinel, Sara Green, Mette N. Svendsen

“…We show how the building of biological clocks rests on particular forms of knowing decay: In the academic laboratory, researchers focus on endo-processes of decay that are internal to the person, but when the technology moves to the market, the focus shifts as staff bracket decay as exo-processes, which are seen as resulting from a person's lifestyle. …”
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Analytical Performance of Direct Rapid Nucleic Acid Assay for Detection of SARS-Cov-2 by Ozhiparambil Anilkumar Jagan, Mohammed Muhsin Paraparambil Vellamkott, Anzil Bava, Jayalakshmi Anish, Vinaya Acharya, Muhammed Shakir, Seema Oommen

“…These samples were tested by the Direct Detect® SARS-CoV-2 Detection Kit and by the LabGun® COVID-19 ExoFast RT-PCR Kit. Of 707 specimens tested, 649(91.79%) were negative and 58(8.20%) were positive. …”
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Induction of Conjugation and Zygospore Cell Wall Characteristics in the Alpine <i>Spirogyra mirabilis</i> (Zygnematophyceae, Charophyta): Advantage under Climate Change Scenarios? by Charlotte Permann, Klaus Herburger, Martin Felhofer, Notburga Gierlinger, Louise A. Lewis, Andreas Holzinger

“…The reproductive morphology was characterized by light- and transmission electron microscopy, and the latter allowed the detection of distinctly oriented microfibrils in the exo- and endospore, and an electron-dense mesospore. …”
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Simple Detection of DNA Methyltransferase with an Integrated Padlock Probe by Yuehua Wang, Yingli Han, Fangyu Zhou, Tingting Fan, Feng Liu

“…As the substrate of MTase, the PP was methylated and defended against HpaII, lambda exonuclease, and ExoI cleavage, as well as digestion, by adding MTase and the undestroyed PP started RCA. …”
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