ｍｉＲ－１０３通过抑制ＦＢＷ７的表达促进肝癌细胞增殖

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The research on FBW7 gene enhances antitumor effect of paclitaxel on pancreatic cancer through GSDME-mediated pyroptosis by JIA Yuming, YE Zeng, DENG Yanli, LI Shengchao, ZHANG Zhilei, WANG Chao, XU Xiaowu, QIN Yi, PENG Li

Subjects: “…|pancreatic cancer|fbw7|gsdme|pyroptosis|sensitivity…”
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Gfi-1 promotes proliferation of human cervical carcinoma via targeting of FBW7 ubiquitin ligase expression by Cai H, Zhang F, Li Z

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High‐fat diet aggravates the severity of the in vitro posttraumatic osteoarthritis model through macrophagic FBW7 by Lijun Duan, Yuan Ma, Chen‐Guang Feng, Xing Yu

Subjects: “…FBW7…”
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Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations by H Nayanga Thirimanne, Feinan Wu, Derek H Janssens, Jherek Swanger, Ahmed Diab, Heather M Feldman, Robert A Amezquita, Raphael Gottardo, Patrick J Paddison, Steven Henikoff, Bruce E Clurman

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MDM2 drives resistance to Osimertinib by contextually disrupting FBW7-mediated destruction of MCL-1 protein in EGFR mutant NSCLC by Jiaxin Liu, Lingyun Wei, Qing Miao, Sutong Zhan, Peilin Chen, Wei Liu, Liang Cao, Dong Wang, Hongbing Liu, Jie Yin, Yong Song, Mingxiang Ye, Tangfeng Lv

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Dysregulation of FBW7 in malignant lymphoproliferative disorders by Xin Wan, Wei Guo, Zhumei Zhan, Ou Bai

Subjects: “…FBW7…”
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Intracellular Theileria Parasites PIN Down Host Metabolism by Souhila Medjkane, Jonathan B. Weitzman

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Loss of the Fbw7 tumor suppressor rewires cholesterol metabolism in cancer cells leading to activation of the PI3K-AKT signalling axis by Maria T. Bengoechea-Alonso, Arwa Aldaalis, Johan Ericsson, Johan Ericsson

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FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2 by Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu

Subjects: “…FBW7…”
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Clinical significance of FBXW7 loss of function in human cancers by Jingyi Fan, Marcia Bellon, Mingyi Ju, Lin Zhao, Minjie Wei, Liwu Fu, Christophe Nicot

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NDR1 increases NOTCH1 signaling activity by impairing Fbw7 mediated NICD degradation to enhance breast cancer stem cell properties by Ling-Ling Wang, Xiao-Yun Wan, Chun-Qi Liu, Fei-Meng Zheng

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High-performance gene expression and knockout tools using sleeping beauty transposon system by Kaishun Hu, Yu Li, Wenjing Wu, Hengxing Chen, Zhen Chen, Yin Zhang, Yabin Guo, Dong Yin

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Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence by Aldwin Suryo Rahmanto, Fredrik J. Swartling, Olle Sangfelt

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Fbw7 Inhibits the Progression of Activated B-Cell Like Diffuse Large B-Cell Lymphoma by Targeting the Positive Feedback Loop of the LDHA/lactate/miR-223 Axis by Su Yao, Tairan Guo, Fen Zhang, Yu Chen, Fangping Xu, Donglan Luo, Xinlan Luo, Danyi Lin, Wendan Chen, Zhi Li, Yanhui Liu

Subjects: “…Fbw7…”
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Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation by Alison E. Meyer, Quinlan Furumo, Cary Stelloh, Alex C. Minella, Sridhar Rao

Subjects: “…Fbw7…”
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Smooth muscle cell-specific knockout of FBW7 exacerbates intracranial atherosclerotic stenosis by Yan Shen, Xiufen Chen, Chunling Chi, Han Wang, Jun Xue, Danying Su, Hongwei Wang, Meng Li, Bin Liu, Qi Dong

Subjects: “…FBW7…”
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Emerging roles of Myc in stem cell biology and novel tumor therapies by Go J. Yoshida

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FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer by Zhiyuan Zhou, Bin Zhang, Yue Deng, Suke Deng, Jie Li, Wenwen Wei, Yijun Wang, Jiacheng Wang, Zishan Feng, Mengjie Che, Xiao Yang, Jingshu Meng, Yan Li, Yan Hu, Yajie Sun, Lu Wen, Fang Huang, Yuhan Sheng, Chao Wan, Kunyu Yang

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The Highs and Lows of FBXW7: New Insights into Substrate Affinity in Disease and Development by Claire C. de la Cova

Subjects: “…FBXW7/FBW7/Cdc4/SEL-10…”
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