Black Histories Matter Tekijä Ghachem, Malick, James, Erica C.

“…No one can look at this replica of Monticello and say that it produces a bona fide approximation of the original—and yet this is the very fiction that animates the entire project.…”
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Electrical and synaptic integration of glioma into neural circuits Tekijä Venkatesh, Humsa S., Morishita, Wade, Geraghty, Anna C., Silverbush, Dana, Gillespie, Shawn M., Arzt, Marlene, Tam, Lydia T., Espenel, Cedric, Ponnuswami, Anitha, Ni, Lijun, Woo, Pamelyn J., Taylor, Kathryn R., Agarwal, Amit, Regev, Aviv, Brang, David, Vogel, Hannes, Hervey-Jumper, Shawn, Bergles, Dwight E., Suvà, Mario L., Malenka, Robert C., Monje, Michelle

“…Here we show that neuron and glioma interactions include electrochemical communication through bona fide AMPA receptor-dependent neuron–glioma synapses. …”
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Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer Tekijä Draganov, D, Han, Z, Rana, A, Bennett, N, Irvine, DJ, Lee, PP

“…Statistical modeling confirmed bona fide synergistic activity in both the adjuvant (p = 0.007) and metastatic settings (p < 0.001). …”
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Vetting of 384 TESS Objects of Interest with TRICERATOPS and Statistical Validation of 12 Planet Candidates Tekijä Ricker, George R, Vanderspek, Roland K, Seager, Sara, Guerrero, Natalia M., Shporer, Abraham-Avi

“…We therefore encourage use of this tool to prioritize follow-up observations that confirm bona fide planets and identify false positives originating from nearby stars.…”
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Prophage-like gene transfer agents promote Caulobacter crescentus survival and DNA repair during stationary phase Tekijä Gozzi, Kevin, Tran, Ngat T, Modell, Joshua W, Le, Tung BK, Laub, Michael T

“…Here, we demonstrate that the α-proteobacterium <jats:italic>Caulobacter crescentus</jats:italic> produces bona fide GTAs. The production of <jats:italic>Caulobacter</jats:italic> GTAs is tightly regulated by a newly identified transcription factor, RogA, that represses <jats:italic>gafYZ</jats:italic>, the direct activators of GTA synthesis. …”
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Gene transfer agents promote survival and DNA repair during stationary phase for Caulobacter crescentus Tekijä Gozzi, Kevin Robert

“…Here, I demonstrate that the α-proteobacterium Caulobacter crescentus produces bona fide GTAs. The production of Caulobacter GTAs is tightly regulated by a newly identified transcription factor, RogA, that represses gafYZ, the direct activators of GTA synthesis. …”
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A Souvenir for the Land of Pagodas Tekijä Allen, Christopher H.

“…It considers historiography as a process of multiplicity—even dissensus—and proposes the diasporic souvenir as a mechanism for disrupting narrative regimes of power. ¹ “Propaganda” (n.), from New Latin 𝘱𝘳ō𝘱ā𝘨𝘢𝘯𝘥𝘢, short for 𝘊𝘰𝘯𝘨𝘳𝘦𝘨ā𝘵𝘪ō 𝘥ē 𝘗𝘳ō𝘱ā𝘨𝘢𝘯𝘥ā 𝘍𝘪𝘥ē, “Congregation for Propagating the Faith.” …”
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Prion formation by a yeast GLFG nucleoporin Tekijä Halfmann, Randal Arthur, Wright, Jessica R., Alberti, Simon, Lindquist, Susan, Rexach, Michael

“…Furthermore, we demonstrate that Nup100 can form bona fide prions, thus establishing a previously undiscovered ability of yeast GLFG nucleoporins to adopt this conformational state in vivo.…”
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Regulation of NOD2-dependent NF-kB signaling by tumour suppressor network. Tekijä Suhendra.

“…For the past 10 years, much research has focused on understanding how NOD-like receptor (NLR) family plays a role in innate immunity. NOD2, a bona fide intracellular NLR, is an effective cystolic innate receptor that detects conserved bacterial molecular signatures within the host cytosol. …”
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Cultural attachment : from behavior to computational neuroscience Tekijä Yap, Wei-Jie, Cheon, Bobby, Hong, Ying-yi, Christopoulos, George I.

“…Based on existing robust neuroscience models we associate these concepts and mechanisms with bona fide neurobiological functions to advance an integrative neurobiological model of CA. …”
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Unacceptable circumstances in takeovers Tekijä Ambaras Khan, Mushera Bibi

“…It prohibits the board of the target from taking suchactions, whether during the course of an offer or even before the date of the offer if they have reason to believe that a bona fide offer might be imminent, unless they have obtained their shareholders’ approval. …”
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Molecular mechanisms of premature ageing in a worm model of human Werner syndrome Tekijä Lees, H, Hayley Lees

“…<em>wrn-1</em> overexpression, on the other hand, appears to enhance longevity, suggesting that <em>wrn-1</em> acts as a <em>bona fide</em> anti-gerontogene. The combination of <em>wrn-1</em> mutations with mutation in the worm p53 homologue, cep-1, unexpectedly triggers a novel and very striking enhanced lifespan and healthspan phenotype, termed synthetic super-viability (SSV). …”

Systematic phylogenetic analysis of influenza A virus reveals many novel mosaic genome segments Tekijä Lam, T, Chong, Y, Shi, M, Hon, C, Li, J, Martin, D, Tang, J, Mok, C, Shih, S, Yip, C, Jiang, J, Hui, R, Pybus, O, Holmes, E, Leung, F

“…Although some recent studies have reported bioinformatic evidence of mosaic sequences in a variety of influenza A viruses, it remains controversial as to whether these represent bona fide natural recombination events or laboratory artifacts. …”

Modeling spinal muscular atrophy in Drosophila. Tekijä Chang, H, Dimlich, D, Yokokura, T, Mukherjee, A, Kankel, M, Sen, A, Sridhar, V, Fulga, T, Hart, A, Van Vactor, D, Artavanis-Tsakonas, S

“…These results confirm that our genetic approach is likely to identify bona fide modulators of SMN activity, especially regarding its role at the neuromuscular junction, and as a consequence, may identify putative SMA therapeutic targets.…”

Duplication and neofunctionalization of a horizontally-transferred xyloglucanase as a facet of the red queen co-evolutionary dynamic Tekijä Attah, V, Milner, DS, Fang, Y, Yan, X, Leonard, G, Heitman, J, Talbot, NJ, Richards, TA

“…The functional xyloglucanase variants analysed subtend an ancestral node close to the fungi-oomycetes gene transfer, suggesting the horizontally-transferred gene was a bona fide xyloglucanase. Expression of xyloglucanase paralogs in Nicotiana benthamiana triggers distinct patterns of reactive oxygen species (ROS) generation, demonstrating that enzyme variants differentially stimulate pattern-triggered immunity in plants. …”

Luís Fróis’s História de Japam: aims and methods Tekijä Takamura, JA

“…It refutes the view of the historiography that has considered his magnum opus the História de Japam, produced between 1584-93, as bona fide and as one of the most reliable sources on the basis that he was often either a protagonist or an eyewitness of the events that he relates. …”

Drosophila SMN complex proteins Gemin2, Gemin3, and Gemin5 are components of U bodies. Tekijä Cauchi, R, Sanchez-Pulido, L, Liu, J

“…Through an in silico analysis of the DEAD-box RNA helicases we confirmed that Gemin3 is the bona fide Drosophila orthologue of vertebrate Gemin3 whereas the Drosophila orthologue of Dhh1 is Me31B. …”

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis Tekijä Sonveaux, P, Copetti, T, De Saedeleer, CJ, Végran, F, Verrax, J, Kennedy, KM, Moon, EJ, Dhup, S, Danhier, P, Frérart, F, Gallez, B, Ribeiro, A, Michiels, C, Dewhirst, MW, Feron, O

“…Furthermore, using a variety of functional assays including endothelial cell migration and tubulogenesis together with in vivo imaging of tumor angiogenesis through intravital microscopy and immunohistochemistry, we documented that MCT1 blockers could act as bona fide HIF-1 inhibitors leading to anti-angiogenic effects. …”

Evaluating new malaria vaccine candidates Tekijä Noé, A

“…While these peripheral 'TRM-like cells' differed to bona fide TRM in certain features, such as leucocyte adhesion and T cell differentiation, they were phenotypically similar and indistinguishable in terms of T cell residency transcriptional signatures. …”

Multiple ubiquitin E3 ligase genes antagonistically regulate chloroplast-associated protein degradation Tekijä Mohd. Ali, S, Li, N, Soufi, Z, Yao, J, Johnson, E, Ling, Q, Jarvis, R

“…Thus, SPL1 and SPL2 are bona fide CHLORAD system components with negative and positive regulatory functions that allow for nuanced control of this vital proteolytic pathway.…”