FOXP2. by Nudel, R, Newbury, D

“…The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and language disorder. …”

Dissecting FOXP2 oligomerization and DNA binding by Haeussermann, K, Young, G, Kukura, P, Dietz, H

“…FOXP2 contains several functional domains commonly involved in both nucleic acid-binding and protein oligomerization, such as a polyglutamine-rich region, a C2H2-zinc finger (ZF), and a leucine zipper (LZ), whose roles in the activity of FOXP2 remain largely unknown. …”

FOXP2 confers oncogenic effects in prostate cancer by Xiaoquan Zhu, Chao Chen, Dong Wei, Yong Xu, Siying Liang, Wenlong Jia, Jian Li, Yanchun Qu, Jianpo Zhai, Yaoguang Zhang, Pengjie Wu, Qiang Hao, Linlin Zhang, Wei Zhang, Xinyu Yang, Lin Pan, Ruomei Qi, Yao Li, Feiliang Wang, Rui Yi, Ze Yang, Jianye Wang, Yanyang Zhao

Subjects: “…FOXP2…”
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The FOXP2-Driven Network in Developmental Disorders and Neurodegeneration by Franz Oswald, Patricia Klöble, André Ruland, David Rosenkranz, Bastian Hinz, Bastian Hinz, Falk Butter, Sanja Ramljak, Ulrich Zechner, Ulrich Zechner, Holger Herlyn

“…The transcription repressor FOXP2 is a crucial player in nervous system evolution and development of humans and songbirds. …”
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Expression of FOXP2 is up-regulated in lymphoid malignancies by Campbell, A, Lyne, L, Brown, P, Launchbury, R, Chi, J, Roncador, G, Lawrie, C, Kusec, R, Banham, A

FOXP2 as a molecular window into speech and language. by Fisher, S, Scharff, C

“…Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome characterized by impaired speech development and linguistic deficits. …”

FOXP2, retinoic acid, and language: a promising direction by Antonio eBenítez-Burraco, Cedric eBoeckx

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Foxp2 mutations impair auditory-motor association learning. by Simone Kurt, Simon E Fisher, Günter Ehret

“…Heterozygous mutations of the human FOXP2 transcription factor gene cause the best-described examples of monogenic speech and language disorders. …”
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Functional characterization of two enhancers located downstream FOXP2 by Raúl Torres-Ruiz, Antonio Benítez-Burraco, Marta Martínez-Lage, Sandra Rodríguez-Perales, Paloma García-Bellido

Subjects: “…FOXP2…”
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Mapping of Human FOXP2 Enhancers Reveals Complex Regulation by Martin Becker, Martin Becker, Paolo Devanna, Simon E. Fisher, Simon E. Fisher, Sonja C. Vernes, Sonja C. Vernes

Subjects: “…FOXP2…”
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Functional characterization of two enhancers located downstream FOXP2 by Torres-Ruiz, R, Benítez-Burraco, A, Martínez-Lage, M, Rodríguez-Perales, S, García-Bellido, P

The structure of innate vocalizations in Foxp2-deficient mouse pups. by Gaub, S, Groszer, M, Fisher, S, Ehret, G

“…Heterozygous mutations of the human FOXP2 gene are implicated in a severe speech and language disorder. …”

Generation of mice with a conditional Foxp2 null allele. by French, C, Groszer, M, Preece, C, Coupe, A, Rajewsky, K, Fisher, S

“…Disruptions of the human FOXP2 gene cause problems with articulation of complex speech sounds, accompanied by impairment in many aspects of language ability. …”

The Analysis of the Foxp2 and ASCL1 Expression in Saffron-Treated Mice by Syavash Yazdian, Mina Ramezani, Nastaran Asgarimoghadam

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Sobre el significado del descubrimiento del gen FOXP2 by Víctor Manuel Longa Martínez

“…El objetivo central del presente trabajo es discutir diferentes aspectos relacionados con tal descubrimiento; especialmente, la discusión del significado de FOXP2 con respecto al lenguaje y al desarrollo del lenguaje.…”
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<it>FOXP2 </it>gene and language impairment in schizophrenia: association and epigenetic studies by Moltó María D, Dagnall Adam M, Sanjuán Julio, Tolosa Amparo, Herrero Neus, de Frutos Rosa

“…Previous studies have reported evidence of positive selection for schizophrenia-associated genes specific to the human lineage. <it>FOXP2 </it>shows two important features as a convincing candidate gene for schizophrenia vulnerability: <it>FOXP2 </it>is the first gene related to a language disorder, and it has been subject to positive selection in the human lineage.…”
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Modified sound-evoked brainstem potentials in Foxp2 mutant mice. by Kurt, S, Groszer, M, Fisher, S, Ehret, G

“…Heterozygous mutations of the human FOXP2 gene cause a developmental disorder involving impaired learning and production of fluent spoken language. …”

Molecular evolution of FOXP2, a gene involved in speech and language. by Enard, W, Przeworski, M, Fisher, S, Lai, C, Wiebe, V, Kitano, T, Monaco, A, Pääbo, S

“…Thus, two functional copies of FOXP2 seem to be required for acquisition of normal spoken language. …”

Problematic aspects of the genetic analysis of the specific disorders of the language: FOXP2 as paradigm by A. Benítez-Burraco

“…Objectives: This paper will review this type of evidence (referring to the “language gene” FOXP2 as a leading example, where possible), try to suggest plausible reasons for such a perplexing output, and ultimately discuss if such reasons really explain the genuine aetiology of these conditions. …”
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PolyQ length-based molecular encoding of vocalization frequency in FOXP2 by Serena Vaglietti, Veronica Villeri, Marco Dell’Oca, Chiara Marchetti, Federico Cesano, Francesca Rizzo, Dave Miller, Louis LaPierre, Ilaria Pelassa, Francisco J. Monje, Luca Colnaghi, Mirella Ghirardi, Ferdinando Fiumara

“…Summary: The transcription factor FOXP2, a regulator of vocalization- and speech/language-related phenotypes, contains two long polyQ repeats (Q1 and Q2) displaying marked, still enigmatic length variation across mammals. …”
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