Central Serous Chorioretinopathy: Pathogenesis and Management by Semeraro F, Morescalchi F, Russo A, Gambicorti E, Pilotto A, Parmeggiani F, Bartollino S, Costagliola C

“…There have been a number of interventions used in CSC, including, but not limited to, laser treatment, photodynamic therapy (PDT), intravitreal injection of anti-vascular endothelial growth factor agents, and subthreshold lasers. It is not clear whether there is a clinically important benefit to treating acute CSC, which often resolves spontaneously as part of its natural history. …”
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Hypoxia-induced retinal neovascularization in zebrafish embryos: a potential model of retinopathy of prematurity. by Yu-Ching Wu, Chao-Yuan Chang, Alex Kao, Brian Hsi, Shwu-Huey Lee, Yau-Hung Chen, I-Jong Wang

“…In addition, we demonstrated that the hypoxic insult could be effectively rescued by several antivascular endothelial growth factor agents such as SU5416, bevacizumab, and ranibizumab. …”
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New frontiers of retinal therapeutic intervention: a critical analysis of novel approaches by Onnisa Nanegrungsunk, Adrian Au, David Sarraf, Srinivas R. Sadda

“…Some advances, such as longer-acting anti-vascular endothelial growth factor agents, port delivery systems, gene therapy, and retinal prosthetics have been approved by the US Food and Drug Administration, and are available for clinical use. …”
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Systemic Cytokines in Retinopathy of Prematurity by Po-Yi Wu, Yuan-Kai Fu, Rey-In Lien, Ming-Chou Chiang, Chien-Chung Lee, Hung-Chi Chen, Yi-Jen Hsueh, Kuan-Jen Chen, Nan-Kai Wang, Laura Liu, Yen-Po Chen, Yih-Shiou Hwang, Chi-Chun Lai, Wei-Chi Wu

“…Although conventional cryotherapy and laser photocoagulation are well established and anti-vascular endothelial growth factor agents are available, less destructive novel therapeutics that can precisely target the signaling pathways are required. …”
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PIMS-TS, the New Paediatric Systemic Inflammatory Disease Related to Previous Exposure to SARS-CoV-2 Infection—“Rheumatic Fever” of the 21st Century? by Violetta Opoka-Winiarska, Ewelina Grywalska, Jacek Roliński

“…Current therapy for PIMS-TS is based on anti-inflammatory treatment: intravenous immunoglobulin (first-line), intravenous glucocorticoids (second-line), or biological therapy (third-line; including interleukin [IL]-1 antagonists, IL-6 receptor blockers, and anti-tumour necrosis factor agents). Vaccination might be good prophylaxis, but the efficacy and safety of the vaccines against <i>SARS-CoV-2</i> have not yet been established in children. …”
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<i>Staphylococcus lugdunensis</i> Endophthalmitis: Case Series and Literature Review by Kuan-Jen Chen, Ming-Hui Sun, Andrew S. H. Tsai, Chi-Chin Sun, Wei-Chi Wu, Chi-Chun Lai

“…<i>S. lugdunensis</i> endophthalmitis have been reported following cataract surgery, trauma, intravitreal injections of anti-vascular endothelial growth factor agents and dexamethasone implant. We report four cases of postoperative <i>S. lugdunensis</i> endophthalmitis after cataract extraction (three patients) and combined pars plana vitrectomy and cataract extraction (one patient). …”
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A mitochondrial therapeutic reverses visual decline in mouse models of diabetes by Nazia M. Alam, William C. Mills, Aimee A. Wong, Robert M. Douglas, Hazel H. Szeto, Glen T. Prusky

“…Unfortunately, managing glycemia or targeting vascular complications with anti-vascular endothelial growth factor agents has shown only limited efficacy in treating the deterioration of vision in diabetic retinopathy. …”
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Profiling Analysis of Histone Modifications and Gene Expression in Lewis Lung Carcinoma Murine Cells Resistant to Anti-VEGF Treatment. by Dong Li, Jiejun Shi, Yanhua Du, Kaiming Chen, Zhenping Liu, Bing Li, Jie Li, Fei Tao, Hua Gu, Cizhong Jiang, Jianmin Fang

“…Tumor cells become resistant after long-term use of anti-VEGF (vascular endothelial growth factor) agents. Our previous study shows that treatment with a VEGF inhibitor (VEGF-Trap) facilitates to develop tumor resistance through regulating angiogenesis-related genes. …”
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The effect of biological agents on antinuclear antibody status in patients with psoriasis: A single-center study by Ömer Kutlu, Pınar Çetinkaya, Tijen Şahin, Hatice Meral Ekşioǧlu

“…We aimed to evaluate the effect of antitumor necrosis factor agents and ustekinumab on ANA status, as well as other factors leading to change in ANA status such as history of phototherapy and methotrexate combination therapy. …”
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Estimated cases of blindness and visual impairment from neovascular age-related macular degeneration avoided in Australia by ranibizumab treatment. by Paul Mitchell, Neil Bressler, Quan V Doan, Chantal Dolan, Alberto Ferreira, Aaron Osborne, Elena Rochtchina, Mark Danese, Shoshana Colman, Tien Y Wong

“…Intravitreal injections of anti-vascular endothelial growth factor agents, such as ranibizumab, have significantly improved the management of neovascular age-related macular degeneration. …”
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ESTRUTURA, CONDUTA E GOVERNANÇA NA CADEIA PRODUTIVA DO LEITE: UM ESTUDO MULTICASO NO RIO GRANDE DO SUL by Raquel Breitenbach, Renato Santos de Souza

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Human T-cell leukemia virus type 1 may invalidate T-SPOT.TB assay results in rheumatoid arthritis patients: A retrospective case-control observational study. by Kunihiko Umekita, Yayoi Hashiba, Kosho Iwao, Chihiro Iwao, Masatoshi Kimura, Yumi Kariya, Kazuyoshi Kubo, Shunichi Miyauchi, Risa Kudou, Yuki Rikitake, Katoko Takajo, Takeshi Kawaguchi, Motohiro Matsuda, Ichiro Takajo, Eisuke Inoue, Toshihiko Hidaka, Akihiko Okayama

“…Interferon-γ release assays rely on the fact that T-lymphocytes release this cytokine when exposed to tuberculosis-specific antigens and are useful in testing for latent tuberculosis infection before initiating biologic therapy, such as anti-tumor necrosis factor agents. However, the reliability of interferon-γ release assays in detecting tuberculosis infection among HTLV-1-positive patients with rheumatoid arthritis (RA) remains unclear. …”
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Implementation of a Teledermatology Electronic Consultation Program to Improve the Care of Patients with Inflammatory Bowel Disease by Ana Echarri, Carmen Pradera, Gema Molina, Carlota Gonzalez Moure, Cristina De las Heras, Rebeca Fraga Iriso, Virginia Ollero, Cristina Echevarria, Javier Mu?iz

“…13, 33.3%), commonly related with anti-tumor necrosis factor agents (70% of the patients) and hidradenitis suppurativa (n?…”
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Ultrastructural features of epiretinal membranes after intravitreal injection of various doses of aflibercept in patients with proliferative diabetic retinopathy by Vira S. Ponomarchuk, N.I. Molchaniuk, M. M. Umanets

“…Anti-vascular endothelial growth factor agents are widely used for prevention of intraoperative and postoperative hemorrhagic complications in vitrectomy for PDR. …”
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Acrodermatitis continua of Hallopeau: clinical perspectives by Smith MP, Ly K, Thibodeaux Q, Bhutani T, Liao W, Beck KM

“…Specifically, rapid and sustained responses have been reported with the use of anti-tumor necrosis factor agents like infliximab, adalimumab, and etanercept; IL-17 inhibitors like secukinumab; IL-12/23 inhibitors like ustekinumab; and IL-1 inhibitors like anakinra. …”
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Host factors related to pneumonia in children under 5 years of age by Wiharjo Hadisuwarno, Retno Asih Setyoningrum, Pirlina Umiastuti

“…Imbalanced interactions among host factors, agents, and environments influence incidence of pneumonia. …”
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A semi-automated machine-learning based workflow for ellipsoid zone analysis in eyes with macular edema: SCORE2 pilot study. by Tyler Etheridge, Ellen T A Dobson, Marcel Wiedenmann, Chandana Papudesu, Ingrid U Scott, Michael S Ip, Kevin W Eliceiri, Barbara A Blodi, Amitha Domalpally

“…<h4>Background and objective</h4>To develop a semi-automated, machine-learning based workflow to evaluate the ellipsoid zone (EZ) assessed by spectral domain optical coherence tomography (SD-OCT) in eyes with macular edema secondary to central retinal or hemi-retinal vein occlusion in SCORE2 treated with anti-vascular endothelial growth factor agents.<h4>Methods</h4>SD-OCT macular volume scans of a randomly selected subset of 75 SCORE2 study eyes were converted to the Digital Imaging and Communications in Medicine (DICOM) format, and the EZ layer was segmented using nonproprietary software. …”
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Efficacy of single-dose intravitreal dexamethasone implantation for retinal vein occlusion patients with refractory macular edema: A systematic review and meta-analysis by Qiongzhen Yuan, Yunxia Gao, Yilin Liu, Hanyue Xu, Tong Wang, Ming Zhang

“…Purpose: To assess the functional and anatomical consequences of single-dose dexamethasone (DEX) implants for the treatment of refractory macular edema (ME) secondary to retinal vein occlusion (RVO) after anti-vascular endothelial growth factor agents.Methods: A literature search of studies on switching therapy to DEX implants from anti-VEGF agents in refractory RVO patients was performed with five electronic databases (PubMed, Embase, Web of Science, MEDLINE, and Cochrane Library) prior to January 2022. …”
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An Immunohistochemical Study of Vascular Endothelial Growth Factor Expression in Meningioma and Its Correlation with Tumor Grade by Parvin Mahzouni, Elham Aghili, Behnaz Sabaghi

“…Thus, anti-vascular endothelial growth factor agents such as bevacizumab might be useful as a treatment of this condition.…”
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Orbital Inflammatory Complications of Crohn’s Disease: A Rare Case Series by Tanya M Monaghan, Giorgio Albanese, Philip Kaye, James D Thomas, Lorraine C Abercrombie, Gordon W Moran

“…In all cases, symptoms improved with oral corticosteroids or nonsteroidal drugs in combination with anti-tumor necrosis factor agents. Inflammatory bowel disease–related orbital complications are rare but potentially vision-threatening. …”
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