Broadly Neutralizing Antibodies for HIV-1 Prevention by Stephen R. Walsh, Michael S. Seaman

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With great power, comes great responsibility: the importance of broadly measuring Fc-mediated effector function early in the antibody development process by Silvia Crescioli, Shashi Jatiani, Lenny Moise

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Understanding Fc function for rational vaccine design against pathogens by Kathryn A. Bowman, Paulina Kaplonek, Ryan P. McNamara

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Dissecting Fc signatures of protection in neonates following maternal influenza vaccination in a placebo-controlled trial by Carolyn M. Boudreau, John S. Burke, IV, Kiel D. Shuey, Caitlin Wolf, Joanne Katz, James Tielsch, Subarna Khatry, Steven C. LeClerq, Janet A. Englund, Helen Y. Chu, Galit Alter

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An Fc-Competent Anti-Human TIGIT Blocking Antibody Ociperlimab (BGB-A1217) Elicits Strong Immune Responses and Potent Anti-Tumor Efficacy in Pre-Clinical Models by Xin Chen, Liu Xue, Xiao Ding, Jing Zhang, Lei Jiang, Sha Liu, Hongjia Hou, Bin Jiang, Liang Cheng, Qing Zhu, Lijie Zhang, Xiaosui Zhou, Jie Ma, Qi Liu, Yucheng Li, Zhiying Ren, Beibei Jiang, Xiaomin Song, Jing Song, Wei Jin, Min Wei, Zhirong Shen, Xuesong Liu, Lai Wang, Kang Li, Tong Zhang

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Leveraging Antibody, B Cell and Fc Receptor Interactions to Understand Heterogeneous Immune Responses in Tuberculosis by Stephen M. Carpenter, Stephen M. Carpenter, Lenette L. Lu, Lenette L. Lu, Lenette L. Lu

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Coronavac inactivated vaccine triggers durable, cross-reactive Fc-mediated phagocytosis activities by Lili Wang, Chuang Li, Wanting Li, Liwei Zhao, Tiantian Zhao, Lin Chen, Ming Li, Jing Fan, Jiayan Li, Chao Wu, Yuxin Chen

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A Case for Antibodies as Mechanistic Correlates of Immunity in Tuberculosis by Jeffrey Y. Kawahara, Jeffrey Y. Kawahara, Edward B. Irvine, Edward B. Irvine, Galit Alter

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CoronaVac-induced antibodies that facilitate Fc-mediated neutrophil phagocytosis track with COVID-19 disease resolution by Chuang Li, Jie Yu, Rahma Issa, Lili Wang, Mingzhe Ning, Shengxia Yin, Jie Li, Chao Wu, Yuxin Chen

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Assessment of the role of afucosylated glycoforms on the in vitro antibody-dependent phagocytosis activity of an antibody to Aβ aggregates by Allyson Kwiatkowski, Carl Co, Sei Kameoka, An Zhang, John Coughlin, Tom Cameron, Eric Chiao, Svetlana Bergelson, Cullen Schmid Mason

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Proteolytic single hinge cleavage of pertuzumab impairs its Fc effector function and antitumor activity in vitro and in vivo by Hao-Ching Hsiao, Xuejun Fan, Robert E. Jordan, Ningyan Zhang, Zhiqiang An

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Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions by Andrea R. Shiakolas, Kevin J. Kramer, Daniel Wrapp, Simone I. Richardson, Alexandra Schäfer, Steven Wall, Nianshuang Wang, Katarzyna Janowska, Kelsey A. Pilewski, Rohit Venkat, Robert Parks, Nelia P. Manamela, Nagarajan Raju, Emilee Friedman Fechter, Clinton M. Holt, Naveenchandra Suryadevara, Rita E. Chen, David R. Martinez, Rachel S. Nargi, Rachel E. Sutton, Julie E. Ledgerwood, Barney S. Graham, Michael S. Diamond, Barton F. Haynes, Priyamvada Acharya, Robert H. Carnahan, James E. Crowe, Jr., Ralph S. Baric, Lynn Morris, Jason S. McLellan, Ivelin S. Georgiev

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HIV Broadly Neutralizing Antibodies Expressed as IgG3 Preserve Neutralization Potency and Show Improved Fc Effector Function by Simone I. Richardson, Simone I. Richardson, Frances Ayres, Nelia P. Manamela, Brent Oosthuysen, Zanele Makhado, Bronwen E. Lambson, Bronwen E. Lambson, Lynn Morris, Lynn Morris, Lynn Morris, Penny L. Moore, Penny L. Moore, Penny L. Moore

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Requirement of Fc-Fc Gamma Receptor Interaction for Antibody-Based Protection against Emerging Virus Infections by Shamus P. Keeler, Julie M. Fox

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Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function by Jennifer L. Schwedler, Maxwell A. Stefan, Christine E. Thatcher, Peter R. McIlroy, Anupama Sinha, Ashlee M. Phillips, Christopher A. Sumner, Colleen M. Courtney, Christina Y. Kim, Dina R. Weilhammer, Brooke Harmon

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Repeated COVID-19 mRNA vaccination results in IgG4 class switching and decreased NK cell activation by S1-specific antibodies in older adults by Anne T. Gelderloos, Marije K. Verheul, Irene Middelhof, Mary-Lène de Zeeuw-Brouwer, Robert S. van Binnendijk, Anne-Marie Buisman, Puck B. van Kasteren

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Plant-Produced Anti-Zika Virus Monoclonal Antibody Glycovariant Exhibits Abrogated Antibody-Dependent Enhancement of Infection by Ming Yang, Haiyan Sun, Huafang Lai, Biswas Neupane, Fengwei Bai, Herta Steinkellner, Qiang Chen

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Multivalent Rhamnose‐Modified EGFR‐Targeting Nanobody Gains Enhanced Innate Fc Effector Immunity and Overcomes Cetuximab Resistance via Recruitment of Endogenous Antibodies by Yanchun Li, Han Lin, Haofei Hong, Dan Li, Liang Gong, Jie Zhao, Zheng Wang, Zhimeng Wu

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Decay of Fc-dependent antibody functions after mild to moderate COVID-19 by Wen Shi Lee, Kevin John Selva, Samantha K. Davis, Bruce D. Wines, Arnold Reynaldi, Robyn Esterbauer, Hannah G. Kelly, Ebene R. Haycroft, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, P. Mark Hogarth, Deborah Cromer, Miles P. Davenport, Amy W. Chung, Stephen J. Kent

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Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection by M. Muenchhoff, A. W. Chung, J. Roider, Anne-Sophie Dugast, Simone Richardson, Henrik Kløverpris, Alasdair Leslie, Thumbi Ndung’u, Penny Moore, Galit Alter, Philip J. R. Goulder

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