Characterizing Arctic sea ice topography using high-resolution IceBridge data by A. A. Petty, M. C. Tsamados, N. T. Kurtz, S. L. Farrell, T. Newman, J. P. Harbeck, D. L. Feltham, J. A. Richter-Menge

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The effects of assimilating a sub-grid-scale sea ice thickness distribution in a new Arctic sea ice data assimilation system by N. Williams, N. Byrne, D. Feltham, P. J. Van Leeuwen, P. J. Van Leeuwen, R. Bannister, D. Schroeder, A. Ridout, L. Nerger

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Smartphone Technology to Remotely Measure Postural Sway during Double- and Single-Leg Squats in Adults with Femoroacetabular Impingement and Those with No Hip Pain by Charlotte J. Marshall, Charlotte Ganderton, Adam Feltham, Doa El-Ansary, Adrian Pranata, John O’Donnell, Amir Takla, Phong Tran, Nilmini Wickramasinghe, Oren Tirosh

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A Feasibility Trial of Power Up: Smartphone App to Support Patient Activation and Shared Decision Making for Mental Health in Young People by Edbrooke-Childs, Julian, Edridge, Chloe, Averill, Phoebe, Delane, Louise, Hollis, Chris, Craven, Michael P, Martin, Kate, Feltham, Amy, Jeremy, Grace, Deighton, Jessica, Wolpert, Miranda

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Power Up: Patient and public involvement in developing a shared decision-making app for mental health by Chloe L Edridge, Julian Edbrooke-Childs, Kate Martin, Louise Delane, Phoebe Averill, Amy Feltham, Jessica Rees, Grace Jeremy, Louise Chapman, Michael P Craven, Miranda Wolpert

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Looking back to move forward: reflections on the strengths and challenges of the COVID-19 UK mental health research response by Demokowicz, O, Panayiotou, M, Parsons, SD, Feltham, A, Arseneault, L, Ingram, B, Patalay, P, Edge, D, Pierce, M, Creswell, C, Victor, C, O-Connor, RC, Qualter, P

Modeling sea ice by Golden, KM, Bennetts, LG, Cherkaev, E, Eisenman, I, Feltham, D, Horvat, C, Hunke, E, Jones, C, Perovich, DK, Ponte-Castañeda, P, Strong, C, Sulsky, D, Wells, AJ

Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence by Zhang, H, Alsaleh, G, Feltham, J, Sun, Y, Napolitano, G, Riffelmacher, T, Charles, P, Frau, L, Hublitz, P, Yu, Z, Mohammed, S, Ballabio, A, Balabanov, S, Mellor, J, Simon, A

Transcriptional changes are regulated by metabolic pathway dynamics but decoupled from protein levels by Feltham, JE, Xi, S, Murray, SC, Wouters, M, Urdiain-Arraiza, J, Heilig, R, George, C, Townley, AF, Roberts, E, Kessler, BM, Liberatori, S, Charles, PD, Angel, A, Fischer, R, Jane Mellor

An assets-based intervention before and after birth to improve breastfeeding initiation and continuation: the ABA feasibility RCT by Joanne L Clarke, Jenny Ingram, Debbie Johnson, Gill Thomson, Heather Trickey, Stephan U Dombrowski, Alice Sitch, Fiona Dykes, Max G Feltham, Christine MacArthur, Tracy Roberts, Pat Hoddinott, Kate Jolly

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Looking Back to Move Forward: Reflections on the Strengths and Challenges of the COVID-19 UK Mental Health Research Response by Ola Demkowicz, Margarita Panayiotou, Sam Parsons, Amy Feltham, Louise Arseneault, Beth Ingram, Praveetha Patalay, Dawn Edge, Dawn Edge, Matthias Pierce, Matthias Pierce, Cathy Creswell, Cathy Creswell, Christina Victor, Rory C. O'Connor, Pamela Qualter

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Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands by Edmond M. Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J. Calleja, Narelle Keating, Rebecca Feltham, Andrew J. Brooks, Shawn S. Li, Sachdev S. Sidhu, Jeffrey J. Babon, Nadia J. Kershaw, Sandra E. Nicholson

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Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands by Edmond M. Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J. Calleja, Narelle Keating, Rebecca Feltham, Andrew J. Brooks, Shawn S. Li, Sachdev S. Sidhu, Jeffrey J. Babon, Nadia J. Kershaw, Sandra E. Nicholson

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An inter-comparison of the mass budget of the Arctic sea ice in CMIP6 models by A. Keen, E. Blockley, D. A. Bailey, J. Boldingh Debernard, M. Bushuk, S. Delhaye, D. Docquier, D. Feltham, F. Massonnet, S. O'Farrell, L. Ponsoni, J. M. Rodriguez, D. Schroeder, N. Swart, T. Toyoda, H. Tsujino, M. Vancoppenolle, K. Wyser

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A cluster randomised controlled trial of an occupational therapy intervention for residents with stroke living in UK care homes (OTCH): study protocol by Sackley Cath M, Burton Chris R, Herron-Marx Sandy, Lett Karen, Mant Jonathan, Roalfe Andrea K, Sharp Leslie J, Sheehan Bart, Stant Katie E, Walker Marion F, Watkins Caroline L, Wheatley Keith, Williams Jane, Yao Guiqing L, Feltham Max G

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Design and characterization of a heterobifunctional degrader of KEAP1 by Hao Chen, Nghi H. Nguyen, Charlene M. Magtoto, Simon A. Cobbold, Grace M. Bidgood, Lizeth G. Meza Guzman, Lachlan W. Richardson, Jason Corbin, Amanda E. Au, Bernhard C. Lechtenberg, Rebecca Feltham, Kate D. Sutherland, Christoph Grohmann, Sandra E. Nicholson, Brad E. Sleebs

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Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1’s Cytotoxic Potential by Rebecca Feltham, Kunzah Jamal, Tencho Tenev, Gianmaria Liccardi, Isabel Jaco, Celia Monteiro Domingues, Otto Morris, Sidonie Wicky John, Alessandro Annibaldi, Marcella Widya, Conor J. Kearney, Danielle Clancy, Paul R. Elliott, Timo Glatter, Qi Qiao, Andrew J. Thompson, Alexey Nesvizhskii, Alexander Schmidt, David Komander, Hao Wu, Seamus Martin, Pascal Meier

“…Together, our findings demonstrate that Mind Bomb E3 ubiquitin ligases can function as additional checkpoint of cytokine-induced cell death, selectively protecting cells from the cytotoxic effects of TNF. : Feltham et al. show that MIB2 directly ubiquitylates RIPK1 upon TNF stimulation, suppressing the cytotoxic potential of RIPK1 and acting as a checkpoint within the TNF signaling pathway. …”
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XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation by Kate E. Lawlor, Rebecca Feltham, Monica Yabal, Stephanie A. Conos, Kaiwen W. Chen, Stephanie Ziehe, Carina Graß, Yifan Zhan, Tan A. Nguyen, Cathrine Hall, Angelina J. Vince, Simon M. Chatfield, Damian B. D’Silva, Kenneth C. Pang, Kate Schroder, John Silke, David L. Vaux, Philipp J. Jost, James E. Vince

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Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms by Christoph Grohmann, Charlene M. Magtoto, Joel R. Walker, Ngee Kiat Chua, Anna Gabrielyan, Mary Hall, Simon A. Cobbold, Stephen Mieruszynski, Martin Brzozowski, Daniel S. Simpson, Hao Dong, Bridget Dorizzi, Annette V. Jacobsen, Emma Morrish, Natasha Silke, James M. Murphy, Joan K. Heath, Andrea Testa, Chiara Maniaci, Alessio Ciulli, Guillaume Lessene, John Silke, Rebecca Feltham

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Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death by Daniel Frank, Sarah E. Garnish, Jarrod J. Sandow, Ashley Weir, Lin Liu, Elise Clayer, Lizeth Meza, Maryam Rashidi, Simon A. Cobbold, Simon R. Scutts, Marcel Doerflinger, Holly Anderton, Kate E. Lawlor, Najoua Lalaoui, Andrew J. Kueh, Vik Ven Eng, Rebecca L. Ambrose, Marco J. Herold, Andre L. Samson, Rebecca Feltham, James M. Murphy, Gregor Ebert, Jaclyn S. Pearson, James E. Vince

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