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    Deletion of the Histone Deacetylase HdaA in Endophytic Fungus <i>Penicillium chrysogenum</i> Fes1701 Induces the Complex Response of Multiple Bioactive Secondary Metabolite Production and Relevant Gene Cluster Expression by Zhuang Ding, Haibo Zhou, Xiao Wang, Huiming Huang, Haotian Wang, Ruiyan Zhang, Zhengping Wang, Jun Han

    Published 2020-08-01
    “…Here, we report the pleiotropic effects of the epigenetic regulator HdaA (histone deacetylase) on secondary metabolite production and the associated biosynthetic gene clusters (BGCs) expression in the plant endophytic fungus <i>Penicillium chrysogenum</i> Fes1701. Deletion of the <i>hdaA</i> gene in strain Fes1701 induced a significant change of the secondary metabolite profile with the emergence of the bioactive indole alkaloid meleagrin. …”
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    L’entrepreneuriat touristique local : une opportunité d’inversion du processus de marginalisation d’un centre historique ? Une analyse dans la médina de Fès au Maroc by Merryl Joly

    Published 2022-12-01
    “…The latter remain on the margins of discussions within the ARMH-Fès, when they are not excluded. Those who only have the status of "house ready to rent" appear in a fragile position. …”
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