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Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells
Published 2020-02-01“…Taken together these results indicate that TRPC4 and 5 channels support persistent firing in CA1 pyramidal neurons. …”
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Spin‐Decoupled Interference Metasurfaces for Complete Complex‐Vectorial‐Field Control and Five‐Channel Imaging
Published 2022-12-01“…For proof‐of‐concept demonstration, two five‐channel meta‐holograms for imaging and information encryption are designed and experimentally characterized. …”
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Higher order mode supercontinuum generation in tantalum pentoxide (Ta2O5) channel waveguide
Published 2021-04-01“…Abstract We fabricated tantalum pentoxide (Ta2O5) channel waveguides and used them to experimentally demonstrate higher-order mode supercontinuum (SC) generation. …”
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Key Role of the Membrane Trafficking of Nav1.5 Channel Protein in Antidepressant-Induced Brugada Syndrome
Published 2018-09-01Get full text
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Maximal Ratio Combining Detection in OFDM Systems with Virtual Carriers Over V2V Channels
Published 2023-07-01Get full text
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Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling
Published 2020-06-01“…Instead, [Ca2+]i changes were sensitive to the specific voltage-gated sodium (NaV) channel blocker tetrodotoxin. Consistent with the conjecture that Ca2+ enters through the NaV channel pore, the optically resolved ICa in the axon initial segment overlapped with the activation kinetics of NaV channels and heterologous expression of NaV1.2 in HEK-293 cells revealed a tetrodotoxin-sensitive [Ca2+]i rise. …”
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Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome
Published 2009-08-01“…The structural-functional study of the Nav1.5 channel advances our understanding of its pathophysiolgocial function.…”
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Structure–Function Relationship and Physiological Roles of Transient Receptor Potential Canonical (TRPC) 4 and 5 Channels
Published 2019-12-01“…In this article, we tried to elaborate recent findings of Cryo-EM (cryogenic-electron microscopy) based structural information of TRPC 4 and 5 channels and domain-specific functions of the channel, such as G-protein mediated activation mechanism, extracellular modification of the channel, homo/hetero-tetramerization, and pharmacological gating mechanisms.…”
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Novel AoD Estimation Algorithms for WSSUS and Non-WSSUS V2V Channel Modeling
Published 2022-08-01“…These results are in agreements with theoretical ones, indicating that the proposed algorithms are practical for estimating the WSSUS and non-WSSUS MIMO V2V channel characteristics.…”
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Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation
Published 2021-04-01“…G protein‐activated inward‐rectifying potassium (K+) channels (Kir3/GIRK) participate in cell excitability. The GIRK5 channel is present in Xenopus laevis oocytes. In an attempt to investigate the physiological role of GIRK5, we identified a noncanonical di‐arginine endoplasmic reticulum (ER) retention motif (KRXY). …”
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Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function
Published 2023-03-01Subjects: “…KV1.5 channels…”
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Activity dependent inhibition of TRPC1/4/5 channels by duloxetine involves voltage sensor-like domain
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Mechanisms of PKA-Dependent Potentiation of Kv7.5 Channel Activity in Human Airway Smooth Muscle Cells
Published 2018-07-01“…Here we provide evidence that Kv7.5 channels are natively expressed in primary cultures of human ASMCs and that they conduct currents which are robustly enhanced in response to activation of the βAR/cyclic adenosine monophosphate (cAMP)/PKA pathway. …”
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Effect of allisartan on blood pressure and left ventricular hypertrophy through Kv1.5 channels in hypertensive rats
Published 2022-04-01“…Western blot analysis also confirmed the increased expression of Kv1.5 channel. Conclusion The results showed that allisartan lowers BP and improves left ventricular remodeling through increased expression of Kv1.5 mRNA.…”
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A Novel GBSM for Non-Stationary V2V Channels Allowing 3D Velocity Variations
Published 2021-05-01Subjects: “…V2V channel…”
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Diagnostic yield and variant reassessment in the genes encoding Nav1.5 channel in Russian patients with Brugada syndrome
Published 2022-08-01Subjects: Get full text
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