Editorial: Psychiatric and Pharmacotoxicological Insights on Appearance and Performance Enhancing Drugs by Simona Zaami, Annagiulia Di Trana, Óscar García-Algar, Enrico Marinelli, Francesco Paolo Busardò

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Gabapentinoid-related deaths: An alarming global trend or just a special challenge within the long tail of the giant opioid epidemic? by Udo Bonnet, Volker Auwärter, Norbert Scherbaum

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Site-Directed Spin Labeling EPR Spectroscopy for Determination of Albumin Structural Damage and Hypoalbuminemia in Critical COVID-19 by Ekaterina Georgieva, Yanka Karamalakova, Georgi Arabadzhiev, Vasil Atanasov, Rositsa Kostandieva, Mitko Mitev, Vanya Tsoneva, Yovcho Yovchev, Galina Nikolova

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EtG Quantification in Hair and Different Reference Cut-Offs in Relation to Various Pathologies: A Scoping Review by Valentina Triolo, Mario Spanò, Roberto Buscemi, Simona Gioè, Ginevra Malta, Marija Čaplinskiene, Fabio Vaiano, Elisabetta Bertol, Stefania Zerbo, Giuseppe Davide Albano, Antonina Argo

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Metabolic Profile Analysis of Designer Benzodiazepine Etizolam in Zebrafish and Human Liver Microsomes by Zhaowei Jie, Shiyang Qin, Wenfang Zhang, Jifen Wang, Jianghai Lu, Ge Qin, Xiaolong Hou, Peng Xu

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Pyrrolidinyl Synthetic Cathinones α-PHP and 4F-α-PVP Metabolite Profiling Using Human Hepatocyte Incubations by Jeremy Carlier, Xingxing Diao, Raffaele Giorgetti, Francesco P. Busardò, Marilyn A. Huestis

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Enhancing the Evidence with Algorithms: How Artificial Intelligence Is Transforming Forensic Medicine by Alin-Ionut Piraianu, Ana Fulga, Carmina Liana Musat, Oana-Roxana Ciobotaru, Diana Gina Poalelungi, Elena Stamate, Octavian Ciobotaru, Iuliu Fulga

“…These included forensic identification, ballistics and additional factors of shooting, traumatic injuries, post-mortem interval estimation, forensic toxicology, sexual assaults/rape, crime scene reconstruction, virtual autopsy, and medical act quality evaluation. …”
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Gas Chromatography—Fourier Transform Infrared Spectroscopy for Unambiguous Determination of Illicit Drugs: A Proof of Concept by Tania M. G. Salerno, Paola Donato, Giampietro Frison, Luca Zamengo, Luigi Mondello, Luigi Mondello, Luigi Mondello, Luigi Mondello

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Genetic variants associated with dengue hemorrhagic fever. A systematic review and meta-analysis by Mohammed Kanan, Mohammed Naffaa, Ahmed Alanazi, Faiz Nasser, Ahad Amer Alsaiari, Mazen Almehmadi, Ali Assiry, Hisham Muzafar, Hejab Katam, Abdullah Arar, Syed Mohammed Basheeruddin Asdaq, Abida, Mohd Imran, Tafadzwa Dzinamarira

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The Critical Assessment of Oxidative Stress Parameters as Potential Biomarkers of Carbon Monoxide Poisoning by Piotr Hydzik, Renata Francik, Sławomir Francik, Ewa Gomółka, Ebru Derici Eker, Mirosław Krośniak, Maciej Noga, Kamil Jurowski

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Prescription drugs with potential for misuse: protocol for a multi-indicator analysis of supply, detection and the associated health burden in Ireland between 2010 and 2020 by Gráinne Cousins, Kathleen E Bennett, Paul Corcoran, Ella Arensman, Eamon Keenan, Suzi Lyons, Louise Durand, Aoife O’Kane, Julie Tierney, Richard Maguire, Siobhán Stokes, Deirdre O’Reilly, María Otero Vázquez, Yvonne Kavanagh

“…The second study aims to estimate trends in the detection of PDPM across multiple early warning systems using national forensic toxicology data. The third study aims to quantify the health burden associated with PDPM nationally, using epidemiological indicators of drug-poisoning deaths, non-fatal intentional drug overdose presentations to hospitals and drug treatment demand.Methods and analysis A retrospective observational study design, with repeated cross-sectional analyses, using negative binomial regression models or, where appropriate, joinpoint regression.Ethics and dissemination The study has received approval from the RCSI Ethics Committee (REC202202020). …”
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Direct Application of 3-Maleimido-PROXYL for Proving Hypoalbuminemia in Cases of SARS-CoV-2 Infection: The Potential Diagnostic Method of Determining Albumin Instability and Oxidiz... by Ekaterina Georgieva, Vasil Atanasov, Rositsa Kostandieva, Vanya Tsoneva, Mitko Mitev, Georgi Arabadzhiev, Yovcho Yovchev, Yanka Karamalakova, Galina Nikolova

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Forensic chemical analysis of hydrogen gas explosions in sprinkler pipes by Songhie An, Sungwan Park

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Dried Blood Spot in Toxicology: Current Knowledge by Agnieszka Niemiec

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COVID-19 Complications: Oxidative Stress, Inflammation, and Mitochondrial and Endothelial Dysfunction by Ekaterina Georgieva, Julian Ananiev, Yovcho Yovchev, Georgi Arabadzhiev, Hristo Abrashev, Despina Abrasheva, Vasil Atanasov, Rositsa Kostandieva, Mitko Mitev, Kamelia Petkova-Parlapanska, Yanka Karamalakova, Iliana Koleva-Korkelia, Vanya Tsoneva, Galina Nikolova

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Drug adherence and psychological factors in patients with apparently treatment‐resistant hypertension: Yes but which ones? by Coralie M. G. Georges, Marco Pappaccogli, Elvira Fanelli, Géraldine Petit, Sabrina Ritscher, Marilucy Lopez‐Sublet, Achille Bapolisi, Pierre Wallemacq, Franco Rabbia, Philippe deTimary, Stefan W. Toennes, Alexandre Persu

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Corrigendum to ‘An unusual suicide by carbon monoxide intoxication: 91% HbCO saturation in a sealed setting’ [Emerging Trends in Drugs, Addictions, and Health Volume 1, 2021, 10002... by Davide Ferorelli, Gabriele Mandarelli, Lorenzo Spagnolo, Federica Misceo, Giuseppe Strisciullo, Lorenzo Polo, Biagio Solarino, Alessandro Dell'Erba

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Analysis of the autopsy, toxicological, and psychiatric reports of Portugal’s first major forensic case: part III by Ricardo Jorge Dinis-Oliveira

“…This famous poisoning had international repercussions for decades, with the participation of several forensic experts that made the history of forensic sciences, namely forensic toxicology and pathology. This third work aims to collect, restore, and analyse all the forensic evidence, particularly from the autopsy, toxicological, and psychiatric forensic reports. …”
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Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain by Zhuang Peng, Sha Peng, Kangguang Lin, Bin Zhao, Lai Wei, Qinhui Tuo, Duanfang Liao, Tifei Yuan, Zhe Shi

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Everolimus decreases [U-13C]glucose utilization by pyruvate carboxylase in breast cancer cells in vitro and in vivo by Gerke Ariaans, Jiske F. Tiersma, Bernardus Evers, Albert Gerding, Stijn J.H. Waaijer, Remco A. Koster, Daan J. Touw, Barbara M. Bakker, Dirk-Jan Reijngoud, Steven de Jong, Mathilde Jalving

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