ABSL-4 Aerobiology Biosafety and Technology at the NIH/NIAID Integrated Research Facility at Fort Detrick by Matthew G. Lackemeyer, Fabian de Kok-Mercado, Jiro Wada, Laura Bollinger, Jason Kindrachuk, Victoria Wahl-Jensen, Jens H. Kuhn, Peter B. Jahrling

“…Here, we provide a brief overview of the animal biosafety level 4 Aerobiology Core at the NIH/NIAID Integrated Research Facility at Fort Detrick, Maryland, USA.…”
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Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey by Gabriella Worwa, Timothy K. Cooper, Steven Yeh, Jessica G. Shantha, Amanda M. W. Hischak, Sarah E. Klim, Russell Byrum, Jonathan R. Kurtz, Scott M. Anthony, Nina M. Aiosa, Danny Ragland, Ji Hyun Lee, Marisa St. Claire, Carl Davis, Rafi Ahmed, Michael R. Holbrook, Jens H. Kuhn, Erica Ollmann Saphire, Ian Crozier

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Computed Tomography Imaging for Monitoring of Marburg Virus Disease: a Nonhuman Primate Proof-Of-Concept Study by Jennifer Sword, Ji Hyun Lee, Marcelo A. Castro, Jeffrey Solomon, Nina Aiosa, Syed M. S. Reza, Winston T. Chu, Joshua C. Johnson, Christopher Bartos, Kurt Cooper, Peter B. Jahrling, Reed F. Johnson, Claudia Calcagno, Ian Crozier, Jens H. Kuhn, Lisa E. Hensley, Irwin M. Feuerstein, Venkatesh Mani

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Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model by Timothy K. Cooper, Louis Huzella, Joshua C. Johnson, Oscar Rojas, Sri Yellayi, Mei G. Sun, Sina Bavari, Amanda Bonilla, Randy Hart, Peter B. Jahrling, Jens H. Kuhn, Xiankun Zeng

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Exposure Route Influences Disease Severity in the COVID-19 Cynomolgus Macaque Model by Sandra L. Bixler, Christopher P. Stefan, Alexandra N. Jay, Franco D. Rossi, Keersten M. Ricks, Charles J. Shoemaker, Alicia M. Moreau, Xiankun Zeng, Jay W. Hooper, David N. Dyer, Ondraya M. Frick, Jeffrey W. Koehler, Brian J. Kearney, Nina DiPinto, Jun Liu, Samantha D. Tostenson, Tamara L. Clements, Jeffrey M. Smith, Joshua A. Johnson, Kerry L. Berrier, Heather L. Esham, Korey L. Delp, Susan R. Coyne, Holly A. Bloomfield, Paul A. Kuehnert, Kristen Akers, Kathleen M. Gibson, Timothy D. Minogue, Aysegul Nalca, Margaret L. M. Pitt

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Intramuscular [¹⁸F]F-FDG Administration for Successful PET Imaging of Golden Hamsters in a Maximum Containment Laboratory Setting by Hui Wang, Jurgen Seidel, Christopher Bartos, Russell Byrum, Philip J. Sayre, Kurt Cooper, Yu Cong, Dong-Yun Kim, Claudia Calcagno, Jens H. Kuhn, Anya Crane, Jiro Wada, Reed F. Johnson, Dima A. Hammoud, Ji Hyun Lee

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Magnetic Resonance Imaging for Monitoring of Hepatic Disease Induced by Ebola Virus: a Nonhuman Primate Proof-of-Concept Study by Ji Hyun Lee, Claudia Calcagno, Irwin M. Feuerstein, Jeffrey Solomon, Venkatesh Mani, Louis Huzella, Marcelo A. Castro, Joseph Laux, Rebecca J. Reeder, Dong-Yun Kim, Gabriella Worwa, David Thomasson, Katie R. Hagen, Danny R. Ragland, Jens H. Kuhn, Reed F. Johnson

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Acute transient tachypnea following gadoxetate administration in a rhesus macaque during contrast-enhanced magnetic resonance imaging by Nina M. Aiosa, BS, Joseph Laux, BS, ARRT, RT, MR, Oscar Rojas, MS, DVM, Richard S. Bennett, PhD, James Logue, BS, Ji Hyun Lee, PhD, Laura Bollinger, MS, Russell Byrum, BA, Marisa St. Claire, DVM, MS, DACLAM, Irwin M. Feuerstein, MD, MBA, MSHCA

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Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques by Victoria Wahl-Jensen, Joshua C. Johnson, Michael Lauck, Jason T. Weinfurter, Louise H. Moncla, Andrea M. Weiler, Olivia Charlier, Oscar Rojas, Russell Byrum, Dan R. Ragland, Louis Huzella, Erika Zommer, Melanie Cohen, John G. Bernbaum, Yíngyún Caì, Hannah B. Sanford, Steven Mazur, Reed F. Johnson, Jing Qin, Gustavo F. Palacios, Adam L. Bailey, Peter B. Jahrling, Tony L. Goldberg, David H. O’Connor, Thomas C. Friedrich, Jens H. Kuhn

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On-Demand Patient-Specific Phenotype-to-Genotype Ebola Virus Characterization by Brett F. Beitzel, Sheli R. Radoshitzky, Nicholas Di Paola, Jennifer M. Brannan, David Kimmel, Katie Caviness, Veronica Soloveva, Shuiqing Yu, Elena N. Postnikova, Courtney L. Finch, Hu Liu, Laura Prugar, Russell Bakken, John M. Dye, Jeffrey R. Kugelman, James M. Cunningham, Mariano Sanchez-Lockhart, Jens H. Kuhn, Gustavo Palacios

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Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail by Jeffrey R. Kugelman, Johanny Kugelman-Tonos, Jason T. Ladner, James Pettit, Carolyn M. Keeton, Elyse R. Nagle, Karla Y. Garcia, Jeffrey W. Froude, Ana I. Kuehne, Jens H. Kuhn, Sina Bavari, Larry Zeitlin, John M. Dye, Gene G. Olinger, Mariano Sanchez-Lockhart, Gustavo F. Palacios

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Development and Characterization of a cDNA-Launch Recombinant Simian Hemorrhagic Fever Virus Expressing Enhanced Green Fluorescent Protein: ORF 2b’ Is Not Required for In Vitro Vir... by Yingyun Cai, Shuiqing Yu, Ying Fang, Laura Bollinger, Yanhua Li, Michael Lauck, Elena N. Postnikova, Steven Mazur, Reed F. Johnson, Courtney L. Finch, Sheli R. Radoshitzky, Gustavo Palacios, Thomas C. Friedrich, Tony L. Goldberg, David H. O’Connor, Peter B. Jahrling, Jens H. Kuhn

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Acute Late-Stage Myocarditis in the Crab-Eating Macaque Model of Hemorrhagic Smallpox by Reed F. Johnson, Lauren A. Keith, Timothy K. Cooper, Srikanth Yellayi, Nicole M. Josleyn, Krisztina B. Janosko, James D. Pettitt, David Thomasson, Katie R. Hagen, Robin Gross, John G. Bernbaum, Debbie Douglas, Jeffrey Solomon, Mark Martinez, Kurt Cooper, Marisa St. Claire, Danny R. Ragland, Peter B. Jahrling, Jens H. Kuhn, Andrew E. Arai

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A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene by Yingyun Cai, Chengjin Ye, Benson Cheng, Aitor Nogales, Masaharu Iwasaki, Shuiqing Yu, Kurt Cooper, David X. Liu, Randy Hart, Ricky Adams, Tyler Brady, Elena N. Postnikova, Jonathan Kurtz, Marisa St Claire, Jens H. Kuhn, Juan Carlos de la Torre, Luis Martínez-Sobrido

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Natural History of Aerosol-Induced Ebola Virus Disease in Rhesus Macaques by Isaac Downs, Joshua C. Johnson, Franco Rossi, David Dyer, David L. Saunders, Nancy A. Twenhafel, Heather L. Esham, William D. Pratt, John Trefry, Elizabeth Zumbrun, Paul R. Facemire, Sara C. Johnston, Erin L. Tompkins, Nathan K. Jansen, Anna Honko, Anthony P. Cardile

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Natural History of Aerosol Induced Lassa Fever in Non-Human Primates by Isaac L. Downs, Carl I. Shaia, Xiankun Zeng, Joshua C. Johnson, Lisa Hensley, David L. Saunders, Franco Rossi, Kathleen A. Cashman, Heather L. Esham, Melissa K. Gregory, William D. Pratt, John C. Trefry, Kyle A. Everson, Charles B. Larcom, Arthur C. Okwesili, Anthony P. Cardile, Anna Honko

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Virus-encoded miRNAs in Ebola virus disease by Janice Duy, Anna N. Honko, Louis A. Altamura, Sandra L. Bixler, Suzanne Wollen-Roberts, Nadia Wauquier, Aileen O’Hearn, Eric M. Mucker, Joshua C. Johnson, Joshua D. Shamblin, Justine Zelko, Miriam A. Botto, James Bangura, Moinya Coomber, M. Louise Pitt, Jean-Paul Gonzalez, Randal J. Schoepp, Arthur J. Goff, Timothy D. Minogue

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A Model for the Production of Regulatory Grade Viral Hemorrhagic Fever Exposure Stocks: From Field Surveillance to Advanced Characterization of SFTSV by Unai Perez-Sautu, Se Hun Gu, Katie Caviness, Dong Hyun Song, Yu-Jin Kim, Nicholas Di Paola, Daesang Lee, Terry A. Klein, Joseph A. Chitty, Elyse Nagle, Heung-Chul Kim, Sung-Tae Chong, Brett Beitzel, Daniel S. Reyes, Courtney Finch, Russ Byrum, Kurt Cooper, Janie Liang, Jens H. Kuhn, Xiankun Zeng, Kathleen A. Kuehl, Kayla M. Coffin, Jun Liu, Hong Sang Oh, Woong Seog, Byung-Sub Choi, Mariano Sanchez-Lockhart, Gustavo Palacios, Seong Tae Jeong

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Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays by Yíngyún Caì, Masaharu Iwasaki, Brett F. Beitzel, Shuīqìng Yú, Elena N. Postnikova, Beatrice Cubitt, Lisa Evans DeWald, Sheli R. Radoshitzky, Laura Bollinger, Peter B. Jahrling, Gustavo F. Palacios, Juan C. de la Torre, Jens H. Kuhn

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SARS-CoV-2 Infections in Vaccinated and Unvaccinated Populations in Camp Lemonnier, Djibouti, from April 2020 to January 2022 by Catherine E. Arnold, Logan J. Voegtly, Emily K. Stefanov, Matthew R. Lueder, Andrea E. Luquette, Robin H. Miller, Haven L. Miner, Andrew J. Bennett, Lindsay Glang, Tara N. McGinnis, Kristie E. Reisinger, Jae W. Dugan, Michael A. Mangat, Daniel J. Silberger, Rebecca L. Pavlicek, Chaselynn M. Watters, Gregory K. Rice, Francisco Malagon, Regina Z. Cer, Stephen M. Eggan, Kimberly A. Bishop-Lilly

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