Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease by Quek, Jun Ping, Liu, Shuang, Zhang, Zhenzhen, Li, Yan, Ng, Elizabeth Yihui, Loh, Ying Ru, Hung, Alvin W., Luo, Dahai, Kang, CongBao

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Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening by Liqing Huang, Weiwei Wang, Zhimin Zhu, Qianhui Li, Minjun Li, Huan Zhou, Qin Xu, Wen Wen, Qisheng Wang, Feng Yu

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How Size Matters: Diversity for Fragment Library Design by Yun Shi, Mark von Itzstein

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Decomposition of Small Molecules for Fragment-Based Drug Design by Nikita N. Ivanov, Dmitry A. Shulga, Vladimir A. Palyulin

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Targeting the Initiator Protease of the Classical Pathway of Complement Using Fragment-Based Drug Discovery by Blake R. Rushing, Denise L. Rohlik, Sourav Roy, D. Andrew Skaff, Brandon L. Garcia

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Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis by Matic Proj, Martina Hrast, Gregor Bajc, Rok Frlan, Anže Meden, Matej Butala, Stanislav Gobec

Subjects: “…Fragment-based drug discovery…”
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Design, synthesis, and screening of an RNA optimized fluorinated fragment library by Kasper P. Lundquist, Isabella Romeo, Raffaele B. Puglielli, Maëlle Pestalozzi, Marie L. Gram, Emily S. Hudson, Ofri Levi, Yoav S. Arava, Charlotte H. Gotfredsen, Mads H. Clausen

Subjects: “…Fragment-based drug discovery…”
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Targeting the ubiquitin system by fragment-based drug discovery by Cassandra Kennedy, Katherine McPhie, Katrin Rittinger

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Using Structure-guided Fragment-Based Drug Discovery to Target Pseudomonas aeruginosa Infections in Cystic Fibrosis by Sheikh Mohammed Arif, R. Andres Floto, R. Andres Floto, Tom L. Blundell

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Reactivity of Covalent Fragments and Their Role in Fragment Based Drug Discovery by Kirsten McAulay, Alan Bilsland, Marta Bon

Subjects: “…fragment-based drug discovery…”
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Application of Fragment-Based Drug Discovery to Versatile Targets by Qingxin Li

Subjects: “…fragment-based drug discovery…”
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Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design by Gary X. Shaw, Lixin Fan, Scott Cherry, Genbin Shi, Joseph E. Tropea, Xinhua Ji

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High-Throughput Virtual Screening of Compounds with Electrophilic Fragments for New Potential Covalent Inhibitors of Bacterial Proteins by Polina Yakovets, Viktoryia Staravoitava, Yaroslav Faletrov, Vladimir Shkumatov

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The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors—A Spin-Off Discovery from Fragment Screening by Sarah L. Mueller, Panagiotis K. Chrysanthopoulos, Maria A. Halili, Caryn Hepburn, Tom Nebl, Claudiu T. Supuran, Alessio Nocentini, Thomas S. Peat, Sally-Ann Poulsen

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Is the Stalk of the SARS-CoV-2 Spike Protein Druggable? by Ludovico Pipitò, Christopher A. Reynolds, Giuseppe Deganutti

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Exploring Natural Product Fragments for Drug and Probe Discovery by Axel Pahl, Herbert Waldmann, Kamal Kumar

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Fragment‐based drug discovery—the importance of high‐quality molecule libraries by Marta Bon, Alan Bilsland, Justin Bower, Kirsten McAulay

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Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections by Sarah L. Kidd, Thomas J. Osberger, Natalia Mateu, Hannah F. Sore, David R. Spring

Subjects: “…fragment-based drug discovery…”
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Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening by Sabrina R. Mackinnon, Gustavo A. Bezerra, Tobias Krojer, Tamas Szommer, Tamas Szommer, Frank von Delft, Frank von Delft, Paul E. Brennan, Paul E. Brennan, Wyatt W. Yue

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Comparing Fragment Binding Poses Prediction Using HSP90 as a Key Study: When Bound Water Makes the Difference by Giovanni Bolcato, Maicol Bissaro, Mattia Sturlese, Stefano Moro

Subjects: “…fragment-based drug discovery…”
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