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19541
NF-κB/c-Rel deficiency causes Parkinson’s disease-like prodromal symptoms and progressive pathology in mice
Published 2019-05-01“…PD patients manifest a prodromal syndrome that includes olfactory and gastrointestinal dysfunctions years before the frank degeneration of nigrostriatal neurons and appearance of motor symptoms. …”
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19542
Nuovi luoghi dell’abbandono: effetti collaterali dell’”Architettura Miracolosa” in Spagna
Published 2020-11-01“…A cavallo tra il XX ed il XXI secolo, la Spagna è stata interessata da un florido periodo di investimenti sia pubblici che privati in architettura, guidato dal cosiddetto “Effetto Bilbao”, che si suppone abbia inizio con la costruzione del museo Guggenheim nella città basca, ad opera dell’architetto Frank Gehry. Tuttavia, la crisi globale ha determinato un periodo di stagnazione economica, che ha portato alla stasi edilizia. …”
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19543
RETRACTED ARTICLE: A leptospiral AAA+ chaperone–Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of l...
Published 2017-01-01“…Ojcius, Dexter Sun, Yumei Ge, Jinfang Zhao, X. Frank Yang, Lanjuan Li, Jie Yan, Identification of Collagenase as a Critical Virulence Factor for Invasiveness and Transmission of Pathogenic Leptospira Species, The Journal of Infectious Diseases, Volume 209, Issue 7, 1 April 2014, Pages 1105–1115, DOI: 10.1093/infdis/jit659When approached for an explanation, the authors were unable to provide an explanation or verify their original data. …”
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19544
Invasive Cryptococcal Meningitis Presenting as a Skull Base Mass in An Immunocompetent Host: A Case Report
Published 2019-07-01“…Fungal sinusitis with frank invasion through the cranial base and subsequent seeding of the central nervous system is rare, but should be considered in the differential of patients presenting with meningitis and sinus/skull base lesions even without obvious immune compromise. …”
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19545
Subclinical right ventricular dysfunction in patients with asymptomatic type 2 diabetes mellitus: A cross-sectional study
Published 2023-11-01“…This study emphasizes that the early identification of RV diastolic as well as systolic dysfunction in asymptomatic Type 2 diabetic patients can be a helpful tool in halting the progression of disease from subclinical to frank clinical cases, thereby preventing the morbidity and mortality associated with heart failure. …”
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19546
Reflectance adaptive optics findings in a patient with Vogt-Koyanagi-Harada disease
Published 2022-09-01“…At the time of presentation, though vision was improving, and frank serous retinal detachments were absent, spectral domain optical coherence tomography (SD-OCT) showed presence of residual subretinal fluid with disruption of the photoreceptor inner segments and outer segments (IS/OS) involving OU. …”
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19547
Deciphering the pathogenesis of the COL4‐related hematuric nephritis: A genotype/phenotype study
Published 2021-02-01“…Abstract Background Alport syndrome (ATS) is a hereditary progressive hematuric nephropathy associated with sensorineural deafness and ocular abnormalities, which is caused by mutations in the COL4A5 gene (X‐linked ATS) and in two autosomal genes, COL4A4 and COL4A3, responsible of both recessive ATS and, when present in heterozygosity, of a spectrum of phenotypes ranging from isolated hematuria to frank renal disease. Methods Retrospective analysis of the clinical and genetic features of 76 patients from 34 unrelated ATS families (11 with mutations in COL4A5, 11 in COL4A3, and 12 in COL4A4) and genotype/phenotype correlation for the COL4A3/COL4A4 heterozygotes (34 patients from 14 families). …”
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19548
Acknowledgment of Reviewers 2021
Published 2022-01-01“…Bei-Hung Chang Huiping Chen Elizabeth Collins Lori Constantine Joseph Cooke Sebastian Cousins Patrick Coyne LaVera Crawley Sarah Cross Constance Dahlin Barbara Daly Bethany-Rose Daubman Kate Davidoff Amy Davis Horace DeLisser Rony Dev Mindy Dickerman Megan Doherty Julia Downing Emily Earl-Royal Frank Elsner Mary Engel Peter Engeser Emma Ernst Elyse Everett Regina Fink MaryBeth Foglia Liz Forbat Anessa Foxwell Jessica Fry Angelica Fuentes Armesto Brittany Gatta Barbara Given Ali Haider Erin Haley Dana Hansen Takaaki Hasegawa Joshua Hauser Rachel Havyer Kerstin Karen Hein Melissa Hoffman Ryan Hughes Kengo Imai Kenji Ina Anand Iyer Annemarie Jagielo Jill Ann Jarrell Zhimeng Jia Gina Johnson Danielle Jonas Christopher Jones Karen Jooste Ryan Jozwiak Miguel Juli?…”
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19550
Association of Treatment Duration and Clinical Outcomes in Dry Eye Treatment with Sutureless Cryopreserved Amniotic Membrane
Published 2023-09-01“…Marguerite McDonald,1 Susan B Janik,2 Frank W Bowden,3 Amit Chokshi,4 Michael A Singer,5 Sean Tighe,6,7 Olivia G Mead,6 Seema Nanda,8 Mujtaba A Qazi,9 Damon Dierker,10 Adam T Shupe,11 Brittany J McMurren12 1Ophthalmic Consultants of Long Island, Lynbrook, NY, USA; 2Solinsky Eye Care, Kensington, CT, USA; 3Bowden Eye & Associates, Jacksonville, FL, USA; 4Florida Eye Specialists, Jacksonville, FL, USA; 5Medical Center Ophthalmology Associates, San Antonio, TX, USA; 6BioTissue Holdings, Inc, Miami, FL, USA; 7Florida International University Herbert Wertheim College of Medicine, Miami, FL, USA; 8Nanda Dry Eye & Vision Institute, Houston, TX, USA; 9Pepose Vision Institute, Chesterfield, MO, USA; 10Eye Surgeons of Indiana, Indianapolis, IN, USA; 11Royo Eye Care, Marysville, CA, USA; 12Werner Optometry, San Diego, CA, USACorrespondence: Sean Tighe, 7300 Corporate Center Drive, Suite 700, Miami, FL, 33126, USA, Email stighe@biotissue.comBackground: While sutureless, cryopreserved amniotic membrane (cAM) has been shown to significantly improve signs and symptoms of dry eye disease (DED), no studies have assessed the association of cAM treatment duration to the differential response in clinical outcomes.Methods: A multi-center, retrospective study was conducted on patients with moderate-to-severe DED who were treated with self-retained cAM (Prokera® Slim) for 2 to 7 days. …”
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19551
Sleep Disturbance in Musculoskeletal Conditions: Impact of a Digital Care Program
Published 2023-01-01“…Justin K Scheer,1 Fabíola Costa,2 Dora Janela,2 Maria Molinos,2 Anabela C Areias,2 Robert G Moulder,3 Jorge Lains,4,5 Virgílio Bento,2 Vijay Yanamadala,2,6,7 Fernando Dias Correia2,8 1Department of Neurological Surgery, University of California, San Francisco, CA, USA; 2Sword Health, Inc, Draper, UT, USA; 3Institute for Cognitive Science, University of Colorado Boulder, Boulder, CO, USA; 4Rovisco Pais Medical and Rehabilitation Centre, Tocha, Portugal; 5Faculty of Medicine, Coimbra University, Coimbra, Portugal; 6Department of Surgery, Quinnipiac University Frank H. Netter School of Medicine, Hamden, CT, USA; 7Department of Neurosurgery, Hartford Healthcare Medical Group, Westport, CT, USA; 8Neurology Department, Centro Hospitalar e Universitário do Porto, Porto, PortugalCorrespondence: Fernando Dias Correia, Sword Health Inc, 13937 Sprague Lane Ste 100, Draper, UT, 84020, USA, Tel +1 385-308-8034, Fax +1 801-206-3433, Email fcorreia@swordhealth.comBackground: Musculoskeletal (MSK) pain is highly prevalent worldwide, resulting in significant disability, and comorbid sleep disturbances. …”
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19552
HER2 Low Expression in Primary Male Breast Cancer
Published 2024-03-01“…Katleen Nobbe,1 Melanie Erices-Leclercq,1 Frank Foerster,2,3 Robert Förster,4 Stephan E Baldus,5 Christian Rudlowski,1,6 Lars Schröder,7 Sabine Lubig1 1Breast Unit, Lutheran Hospital Bergisch Gladbach, Bergisch Gladbach, Germany; 2Department of Economical Sciences, University of Applied Sciences, Zwickau, Germany; 3Outpatient Department of Gynaecological Oncology and Palliative Care, Chemnitz, Germany; 4Institute for Radiation Oncology, Cantonal Hospital Winterthur, Winterthur, Switzerland; 5Institute for Pathology, Cytology and Molecular Pathology, Bergisch Gladbach, Germany; 6Department of Gynecology, University Hospital Bonn, Bonn, Germany; 7Department of Gynaecology and Obstetrics, Ketteler Krankenhaus, Offenbach, GermanyCorrespondence: Christian Rudlowski, Breast Unit, Lutheran Hospital Bergisch Gladbach, Ferrenbergstrasse 24, Bergisch Gladbach, 51465, Germany, Email c.rudlowski@evk.dePurpose: The introduction of HER2-targeting antibody drug conjugates (ADCs) offers new treatment options for female breast cancer patients (FBC) expressing low levels of HER2 (HER2 low). …”
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19554
Impacts of the Early COVID-19 Pandemic on Depressive Symptoms and Mental Health Among Student-Athletes
Published 2024-03-01“…Christopher S Ahmad,1 Justin E Hellwinkel,1 Rifat Ahmed,1 Frank J Alexander,1 Alan W Reynolds,1 Dana P Piasecki,2,3 Thomas S Bottiglieri,1 T Sean Lynch,1 Charles A Popkin,1 Bryan M Saltzman,2,3 David P Trofa1 1Department of Orthopedic Surgery, Columbia University Irving Medical Center, New York, NY, 10032, USA; 2Sports Medicine Center, OrthoCarolina, Charlotte, NC, 28207, USA; 3Musculoskeletal Institute, Atrium Health, Charlotte, NC, 28207, USACorrespondence: David P Trofa, Columbia University Irving Medical Center, 622 West 168 St, PH-11, New York, NY, 10032, Email dpt2103@cumc.columbia.eduObjective: Social distancing protocols due to the COVID-19 pandemic resulted in premature ending of athletic seasons and cancellation of upcoming seasons, placing significant stress on young athletes. …”
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19555
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19556
Digital Technologies Role in the Preservation of Jewish Cultural Heritage: Case Study Heyman House, Oradea, Romania
Published 2022-10-01“…The Jewish community of Oradea had an important representative in Éva Heyman, a child of the Holocaust, nicknamed “<i>Anne Frank of Transylvania</i>”, which became famous. …”
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19557
Changes Seen, Foreseen and Unforeseen
Published 1993-01-01“…The disciplined Pat Lane, comfortable in the analytical jurisprudence then so dominant in the constitutional law of the High Court of Australia. The mercurial Frank Hutley, whose unpredictable examination questions on the law of succession were every law student’s nightmare. …”
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19558
Latanoprostene Bunod 0.024% in Patients with Open-Angle Glaucoma Switched from Prior Pharmacotherapy: A Retrospective Chart Review
Published 2024-02-01“…Constance O Okeke,1 Nora Lee Cothran,2 Desirae A Brinkley,3 Kamran Rahmatnejad,4 Frank J Rodiño,5 James E Deom6 1Virginia Eye Consultants/CVP, Norfolk, VA, USA; 2The Eye Institute of West Florida, Largo, FL, USA; 3Eye Specialty Group, Memphis, TN, USA; 4Eastern Virginia Medical School, Norfolk, VA, USA; 5Churchill Outcomes Research, Red Bank, NJ, USA; 6Hazleton Eye Specialists, Hazle Township, PA, USACorrespondence: Constance O Okeke, Virginia Eye Consultants/CVP, 241 Corporate Blvd, Norfolk, VA, 23320, USA, Tel +1 757-622-2200, Fax +1 757-622-4866, Email cokeke@cvphealth.comIntroduction: Latanoprostene bunod 0.024% (LBN, Vyzulta®) is a nitric oxide-donating prostaglandin analog (PGA). …”
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19559
From learned value to sustained bias: how reward conditioning changes attentional priority
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19560
A regional comparative analysis of empirical and theoretical flood peak-volume relationships
Published 2016-12-01“…Extreme value copulas (Galambos, Gumbel and Hüsler-Reiss) show the best performance both for synoptic and flash floods, while the Frank copula shows the best performance for snowmelt floods. …”
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