Statin use is not associated with inflammation among Chilean women of Mapuche and non-Mapuche ancestry with gallstones by Sarah S Jackson, Marina Lex, Vanessa Van De Wyngard, Paz Cook, Allan Hildesheim, Ligia A Pinto, Sharon H Jackson, Kelvin Choi, Tsion Zewdu Minas, Héctor Fabio Losada Morales, Juan Carlos Araya, Catterina Ferreccio, Jill Koshiol, Ruth M Pfeiffer

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The Timing and Abundance of IL-2Rβ (CD122) Expression Control Thymic iNKT Cell Generation and NKT1 Subset Differentiation by Hee Yeun Won, Hye Kyung Kim, Assiatu Crossman, Parirokh Awasthi, Ronald E. Gress, Jung-Hyun Park

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Crosstalk between Tumor Cells and Macrophages in Stroma Renders Tumor Cells as the Primary Source of MCP-1/CCL2 in Lewis Lung Carcinoma by Teizo eYoshimura, Mingyong eLiu, Mingyong eLiu, Xin eChen, Xin eChen, Liangzhu eLi, Liangzhu eLi, Ji Ming eWang

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The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes by Kaisa Thorell, Zilia Y. Muñoz-Ramírez, Difei Wang, Santiago Sandoval-Motta, Rajiv Boscolo Agostini, Silvia Ghirotto, Roberto C. Torres, HpGP Research Network, Daniel Falush, M. Constanza Camargo, Charles S. Rabkin

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Cancer targeting by TCR gene-engineered T cells directed against Kita-Kyushu Lung Cancer Antigen-1 by Bridget Marcinkowski, Sanja Stevanović, Sarah R. Helman, Scott M. Norberg, Carylinda Serna, Benjamin Jin, Nikolaos Gkitsas, Tejas Kadakia, Andrew Warner, Jeremy L. Davis, Lisa Rooper, Christian S. Hinrichs

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A Macrohistone Variant Links Dynamic Chromatin Compaction to BRCA1-Dependent Genome Maintenance by Simran Khurana, Michael J. Kruhlak, Jeongkyu Kim, Andy D. Tran, Jinping Liu, Katherine Nyswaner, Lei Shi, Parthav Jailwala, Myong-Hee Sung, Ofir Hakim, Philipp Oberdoerffer

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T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity by Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Jim Boonyaratanakornkit, Anna Wald, Stacy Selke, Mark H. Wener, Chihiro Morishima, Alexander L. Greninger, Michael Gale Jr., Tien-Ying Hsiang, Lichen Jing, Michael R. Holbrook, Ian M. Kaplan, H. Jabran Zahid, Damon H. May, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S. Robins, David M. Koelle

“…T cell testing identified SARS-CoV-2 infection in 68% (55 of 81) of samples with undetectable nAb titers (<1:40) and in 37% (13 of 35) of samples classified as negative by 3 antibody assays.CONCLUSION These results support TCR-based testing as a scalable, reliable measure of past SARS-CoV-2 infection with clinical value beyond serology.TRIAL REGISTRATION Specimens were accrued under trial NCT04338360 accessible at clinicaltrials.gov.FUNDING This work was funded by Adaptive Biotechnologies, Frederick National Laboratory for Cancer Research, NIAID, Fred Hutchinson Joel Meyers Endowment, Fast Grants, and American Society for Transplantation and Cell Therapy.…”
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In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery by Taejin Kim, Kirill A. Afonin, Mathias Viard, Alexey Y Koyfman, Selene Sparks, Eliahu Heldman, Sarina Grinberg, Charles Linder, Robert P Blumenthal, Bruce A Shapiro

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A weakly supervised deep learning-based method for glioma subtype classification using WSI and mpMRIs by Wei-Wen Hsu, Jing-Ming Guo, Linmin Pei, Ling-An Chiang, Yao-Feng Li, Jui-Chien Hsiao, Rivka Colen, Peizhong Liu

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Human Plasma-like Medium Improves T Lymphocyte Activation by Michael A. Leney-Greene, Arun K. Boddapati, Helen C. Su, Jason R. Cantor, Michael J. Lenardo

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Promoting family meals: a review of existing interventions and opportunities for future research by Dwyer L, Oh A, Patrick H, Hennessy E

“…Laura Dwyer,1 April Oh,2 Heather Patrick,1,3 Erin Hennessy4 1Health Behaviors Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA; 2Health Communication and Informatics Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA; 3Live Healthier, Bethesda, MD, USA; 4Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA Abstract: Evidence suggests that regular family meals protect against unhealthy eating and obesity during childhood and adolescence. …”
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Ultrapotent Broadly Neutralizing Human‐llama Bispecific Antibodies against HIV‐1 by Jianliang Xu, Tongqing Zhou, Krisha McKee, Baoshan Zhang, Cuiping Liu, Alexandra F. Nazzari, Amarendra Pegu, Chen‐Hsiang Shen, Jordan E. Becker, Michael F. Bender, Payton Chan, Anita Changela, Ridhi Chaudhary, Xuejun Chen, Tal Einav, Young Do Kwon, Bob C. Lin, Mark K. Louder, Jonah S. Merriam, Nicholas C. Morano, Sijy O'Dell, Adam S. Olia, Reda Rawi, Ryan S. Roark, Tyler Stephens, I‐Ting Teng, Emily Tourtellott‐Fogt, Shuishu Wang, Eun Sung Yang, Lawrence Shapiro, Yaroslav Tsybovsky, Nicole A. Doria‐Rose, Rafael Casellas, Peter D. Kwong

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Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple <italic toggle="yes">Pneumocystis</italic> Species by Liang Ma, Zehua Chen, Da Wei Huang, Ousmane H. Cissé, Jamie L. Rothenburger, Alice Latinne, Lisa Bishop, Robert Blair, Jason M. Brenchley, Magali Chabé, Xilong Deng, Vanessa Hirsch, Rebekah Keesler, Geetha Kutty, Yueqin Liu, Daniel Margolis, Serge Morand, Bapi Pahar, Li Peng, Koen K. A. Van Rompay, Xiaohong Song, Jun Song, Antti Sukura, Sabrina Thapar, Honghui Wang, Christiane Weissenbacher-Lang, Jie Xu, Chao-Hung Lee, Claire Jardine, Richard A. Lempicki, Melanie T. Cushion, Christina A. Cuomo, Joseph A. Kovacs

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Prospective Assessment of SARS-CoV-2 Seroconversion (PASS) study: an observational cohort study of SARS-CoV-2 infection and vaccination in healthcare workers by Belinda M. Jackson-Thompson, Emilie Goguet, Eric D. Laing, Cara H. Olsen, Simon Pollett, K. Monique Hollis-Perry, Santina E. Maiolatesi, Luca Illinik, Kathleen F. Ramsey, Anatalio E. Reyes, Yolanda Alcorta, Mimi A. Wong, Julian Davies, Orlando Ortega, Edward Parmelee, Alyssa R. Lindrose, Matthew Moser, Elizabeth Graydon, Andrew G. Letizia, Christopher A. Duplessis, Anuradha Ganesan, Kathleen P. Pratt, Allison M. Malloy, David W. Scott, Stephen K. Anderson, Andrew L. Snow, Clifton L. Dalgard, John H. Powers, David Tribble, Timothy H. Burgess, Christopher C. Broder, Edward Mitre

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Multi-generational benefits of genetic rescue by Dave P. Onorato, Mark W. Cunningham, Mark Lotz, Marc Criffield, David Shindle, Annette Johnson, Bambi C. F. Clemons, Colin P. Shea, Melody E. Roelke-Parker, Warren E. Johnson, Brett T. McClintock, Kristine L. Pilgrim, Michael K. Schwartz, Madan K. Oli

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Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1 by Xue Zhi Zhao, Wenjie Wang, George T. Lountos, Joseph E. Tropea, Danielle Needle, Yves Pommier, Terrence R. Burke

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Characterization of a Compound Heterozygous SLC2A9 Mutation That Causes Hypouricemia by Jaeho Yoon, Raul Cachau, Victor A. David, Mary Thompson, Wooram Jung, Sun-Ha Jee, Ira O. Daar, Cheryl A. Winkler, Sung-Kweon Cho

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Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection by Hongshuo Song, Elena E. Giorgi, Vitaly V. Ganusov, Fangping Cai, Gayathri Athreya, Hyejin Yoon, Oana Carja, Bhavna Hora, Peter Hraber, Ethan Romero-Severson, Chunlai Jiang, Xiaojun Li, Shuyi Wang, Hui Li, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Nilu Goonetilleke, Brandon F. Keele, David C. Montefiori, Myron S. Cohen, George M. Shaw, Beatrice H. Hahn, Andrew J. McMichael, Barton F. Haynes, Bette Korber, Tanmoy Bhattacharya, Feng Gao

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A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells by Binwu Tang, Asaf Raviv, Dominic Esposito, Kathleen C. Flanders, Catherine Daniel, Bao Tram Nghiem, Susan Garfield, Langston Lim, Poonam Mannan, Ana I. Robles, William I. Smith, Jr., Joshua Zimmerberg, Rea Ravin, Lalage M. Wakefield

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NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy by Sofian Al Shboul, Mohammed El-Sadoni, Ahmad Alhesa, Nisreen Abu Shahin, Dua Abuquteish, Ola Abu Al Karsaneh, Elham Alsharaiah, Mohammad A. Ismail, Liliya Tyutyunyk-Massey, Moureq R. Alotaibi, Victoria Neely, Hisashi Harada, Tareq Saleh

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