Whole genome sequencing for metastatic mutational burden in extraskeletal myxoid chondrosarcoma by Trudy Zou, Rahil Sethi, Jiefei Wang, Gungor Budak, Uma Chandran, Ivy John, Rebecca Watters, Kurt Weiss

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Gene transfer and genome editing for familial hypercholesterolemia by Cesare Canepari, Cesare Canepari, Alessio Cantore, Alessio Cantore

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The COVID-19 explorer—An integrated, whole patient knowledge model of COVID-19 disease by Stephan Brock, Theodoros G. Soldatos, Theodoros G. Soldatos, David B. Jackson, Francesca Diella, Klaus Hornischer, Anne Schäfer, Simon P. Hoerstrup, Simon P. Hoerstrup, Maximilian Y. Emmert, Maximilian Y. Emmert, Maximilian Y. Emmert, Maximilian Y. Emmert

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Editorial: Myocardium regeneration and cardioprotection by Martina Iengo, Ester Topa, Alessandra Cuomo, Maria Cristina Luise, Francesco Fiore, Marika Rizza, Mattia Miccio, Elena Di Sarro, Giuseppe Ciaccio, Chiara Di Lorenzo, Valentina Mercurio, Valentina Mercurio, Valentina Mercurio, Sang-Bing Ong, Sang-Bing Ong, Sang-Bing Ong, Sang-Bing Ong, Sang-Bing Ong, Serena Zacchigna, Serena Zacchigna, Carlo Gabriele Tocchetti, Carlo Gabriele Tocchetti, Carlo Gabriele Tocchetti, Carlo Gabriele Tocchetti

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Editorial: Celebrating the 200th mendel’s anniversary: gene-targeted diagnostics and therapies for cancer by Noah Federman, Erlinda M. Gordon, Erlinda M. Gordon, Sant P. Chawla, Sant P. Chawla, Frederick L. Hall, Frederick L. Hall

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Why should we care about astrocytes in a motor neuron disease? by Katarina Stoklund Dittlau, Katarina Stoklund Dittlau, Ludo Van Den Bosch, Ludo Van Den Bosch

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Editorial: Heart valve diseases: from molecular mechanisms to clinical implications by Jaime Ibarrola, Natalia Lopez-Andres

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Novel modular chimeric antigen receptor spacer for T cells derived from signal regulatory protein alpha Ig-like domains by Jan Koski, Farhana Jahan, Annu Luostarinen, Diana Schenkwein, Seppo Ylä-Herttuala, Seppo Ylä-Herttuala, Helka Göös, Hector Monzo, Päivi M. Ojala, Pilvi Maliniemi, Matti Korhonen

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Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood by Antony M. Rapulana, Antony M. Rapulana, Antony M. Rapulana, Thabo Mpotje, Thabo Mpotje, Omolara O. Baiyegunhi, Hlumani Ndlovu, Theresa K. Smit, Theresa K. Smit, Timothy D. McHugh, Mohlopheni J. Marakalala, Mohlopheni J. Marakalala, Mohlopheni J. Marakalala

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Novel therapeutic for multiple sclerosis protects white matter function in EAE mouse model by Sarah Zerimech, Hung Nguyen, Arthur A. Vandenbark, Arthur A. Vandenbark, Arthur A. Vandenbark, Halina Offner, Halina Offner, Halina Offner, Selva Baltan

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Novel insights into cancer stem cells targeting: CAR-T therapy and epigenetic drugs as new pillars in cancer treatment by Veronica Veschi, Alice Turdo, Giorgio Stassi

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Spatial adjustment of bioenergetics, a possible determinant of contractile adaptation and development of contractile failure by Marten Szibor, Marten Szibor, Marie Mühlon, Torsten Doenst, Jaakko L. O. Pohjoismäki

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The advent of a pan-collagenous CLOVIS POINT for pathotropic targeting and cancer gene therapy, a retrospective by Erlinda M. Gordon, Erlinda M. Gordon, Frederick L. Hall, Frederick L. Hall

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Mitochondrial calcium signaling and redox homeostasis in cardiac health and disease by Tudor-Alexandru Popoiu, Tudor-Alexandru Popoiu, Christoph Maack, Edoardo Bertero, Edoardo Bertero

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Gene therapy and genome editing for type I glycogen storage diseases by Janice Y. Chou, Brian C. Mansfield

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How can we use stem cell-derived cardiomyocytes to understand the involvement of energetic metabolism in alterations of cardiac function? by Sabine Rebs, Sabine Rebs, Katrin Streckfuss-Bömeke, Katrin Streckfuss-Bömeke, Katrin Streckfuss-Bömeke

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Elaborating the potential of Artificial Intelligence in automated CAR-T cell manufacturing by Niklas Bäckel, Simon Hort, Tamás Kis, David F. Nettleton, Joseph R. Egan, John J. L. Jacobs, Dennis Grunert, Robert H. Schmitt, Robert H. Schmitt

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Astrocytes in stroke-induced neurodegeneration: a timeline by Eileen Collyer, Elena Blanco-Suarez

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Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver di... by Claudia Theys, Tineke Vanderhaeghen, Tineke Vanderhaeghen, Evelien Van Dijck, Cedric Peleman, Cedric Peleman, Anne Scheepers, Joe Ibrahim, Ligia Mateiu, Steven Timmermans, Steven Timmermans, Tom Vanden Berghe, Tom Vanden Berghe, Tom Vanden Berghe, Sven M. Francque, Sven M. Francque, Wim Van Hul, Claude Libert, Claude Libert, Wim Vanden Berghe

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Editorial: The role of glial cells in neurodegeneration by Piera Pasinelli, Kathrin Meyer, Kathrin Meyer, Laura Ferraiuolo, Robert A. Culibrk, Rita Sattler

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