Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia by Robert Greite, Sebastian Schott, Li Wang, Lukas Gohlke, Kirill Kreimann, Katja Derlin, Marcel Gutberlet, Martina Schmidbauer, Andreas Leffler, Igor Tudorache, Jawad Salman, Fabio Ius, Ruslan Natanov, Christine Fegbeutel, Axel Haverich, Ralf Lichtinghagen, Anne M. Hüsing, Sibylle vonVietinghoff, Roland Schmitt, Nelli Shushakova, Song Rong, Hermann Haller, Kai M. Schmidt‐Ott, Magnus Gram, Vijith Vijayan, Irina Scheffner, Wilfried Gwinner, Stephan Immenschuh

“…However, additional administration of free heme in this model promoted overt AKI with reduced renal function, increased renal inflammation, and reduced renal perfusion on functional magnetic resonance imaging. Hx treatment attenuated AKI. …”
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Obesity surgery and neural correlates of human eating behaviour: A systematic review of functional MRI studies by Shahd Alabdulkader, Alhanouf S. Al-Alsheikh, Alexander D. Miras, Anthony P. Goldstone

“…Changes in eating behaviour including reductions in appetite and food intake, and healthier food cue reactivity, reward, hedonics and potentially also preference, contribute to weight loss and its health benefits after obesity surgery. Functional magnetic resonance imaging (fMRI) has been increasingly used to interrogate the neural correlates of eating behaviour in obesity, including brain reward-cognitive systems, changes after obesity surgery, and links with alterations in the gut-hormone-brain axis. …”
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Working Memory-Related Effective Connectivity in Huntington’s Disease Patients by Jacob Lahr, Jacob Lahr, Lora Minkova, Lora Minkova, Sarah J. Tabrizi, Julie C. Stout, Stefan Klöppel, Stefan Klöppel, Stefan Klöppel, Stefan Klöppel, Elisa Scheller, Elisa Scheller, Elisa Scheller, the TrackOn-HD Investigators, A. Coleman, J. Decolongon, M. Fan, T. Koren, C. Jauffret, D. Justo, S. Lehericy, K. Nigaud, R. Valabrègue, A. Schoonderbeek, E. P. ‘t Hart, H. Crawford, S. Gregory, D. Hensman Moss, E. Johnson, J. Read, G. Owen, M. Papoutsi, C. Berna, A. Razi, G. Rees, R. I. Scahill, D. Craufurd, R. Reilmann, N. Weber, J. Stout, I. Labuschagne, M. Orth, G. B. Landwehrmeyer, D. Langbehn, H. Johnson, J. Long, J. Mills

“…We used functional magnetic resonance imaging (fMRI) and task fMRI-based dynamic causal modeling (DCM) to evaluate HD-related changes in the neural network underlying working memory (WM). …”
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Altered resting-state brain activity in major depressive disorder comorbid with subclinical hypothyroidism: A regional homogeneity analysis by Shuai Zhao, Jindan Wu, Xiaomei Liu, Yishan Du, Xiaoqin Wang, Yi Xia, Hao Sun, Yinghong Huang, Haowen Zou, Xumiao Wang, Zhilu Chen, Hongliang Zhou, Rui Yan, Hao Tang, Qing Lu, Zhijian Yao

“…Method: Thirty MDD patients (non-comorbid group), 30 MDD patients comorbid with SHypo (comorbid group), 26 patients with SHypo, and 30 healthy controls were recruited for resting-state functional magnetic resonance imaging (rs-fMRI). We used regional homogeneity (ReHo) to examine differences in internal cerebral activity across the four groups. …”
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Acute alcohol induces greater dose-dependent increase in the lateral cortical network functional connectivity in adult than adolescent rats by Sung-Ho Lee, Tatiana A. Shnitko, Li-Ming Hsu, Margaret A. Broadwater, Mabelle Sardinas, Tzu-Wen Winnie Wang, Donita L. Robinson, Ryan P. Vetreno, Fulton T. Crews, Yen-Yu Ian Shih

“…Here, we employ a recently developed functional magnetic resonance imaging (fMRI) protocol to acquire rat brain functional connectivity data and use an established analytical pipeline to examine the effect of sex, age, and alcohol dose on connectivity within and between three major rodent brain networks: default mode, salience, and lateral cortical network. …”
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IL-6, but not TNF-α, response to alcohol cues and acute consumption associated with neural cue reactivity, craving, and future drinking in binge drinkers by Sara K. Blaine, Clayton M. Ridner, Benjamin R. Campbell, Lily Crone, Eric D. Claus, Juliet R. Wilson, Summer N. West, Austin J. McClanahan, Anna S. Siddiq, Isaak M.P. Layman, Richard Macatee, Emily B. Ansell, Jennifer L. Robinson, Darren T. Beck

“…Methods: Thirty-three binge drinkers (BD) and 31 non-binge, social drinkers (SD), matched for demographic and psychological variables, were exposed to alcohol cues and water cues in two separate 7 T functional magnetic resonance imaging (fMRI) scans. Each scan was followed by the Alcohol Taste Test (ATT) of implicit motivation for acute alcohol. …”
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Elevated Levels of Serum Biomarkers Associated with Damage to the CNS Neurons and Endothelial Cells Are Linked with Changes in Brain Connectivity in Breast Cancer Patients with Ves... by Alexandra Nikolaeva, Maria Pospelova, Varvara Krasnikova, Albina Makhanova, Samvel Tonyan, Yurii Krasnopeev, Evgeniya Kayumova, Elena Vasilieva, Aleksandr Efimtsev, Anatoliy Levchuk, Gennadiy Trufanov, Mark Voynov, Maxim Shevtsov

“…In the current study, the levels of intercellular cell adhesion molecule 1 (ICAM-1), platelet/endothelial cell adhesion molecule 1 (PECAM-1), NSE (neuron-specific enolase), and the antibodies recognizing NR-2 subunit of NMDA receptor (NR-2-ab) were measured in the blood serum of BC survivor patients with vestibulo-atactic syndrome (VAS) and associated with the brain connectome data obtained via functional magnetic resonance imaging (fMRI) studies. A total of 21 patients were registered in this open, single-center trial and compared to age-matched healthy female volunteers (control group) (<i>n</i> = 17). …”
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Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression by Ting Zeng, Junjie Li, Lingpeng Xie, Zhaoyang Dong, Qing Chen, Sha Huang, Shuwen Xie, Yuqi Lai, Jun Li, Weixin Yan, YuHua Wang, Zeping Xie, Changlei Hu, Jiayi Zhang, Shanshan Kuang, Yuhong Song, Lei Gao, Zhiping Lv

“…The involvement of Nrf2 in iron metabolism and brain function was assessed using molecular biological techniques and in vivo resting-state functional magnetic resonance imaging (rs-fMRI) through genetic deletion or pharmacologic activation of Nrf2. …”
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High frequency deep brain stimulation of the dorsal raphe nucleus prevents methamphetamine priming-induced reinstatement of drug seeking in rats by Libo Zhang, Shiqiu Meng, Enze Huang, Tianqi Di, Zengbo Ding, Shihao Huang, Wenjun Chen, Jiayi Zhang, Shenghong Zhao, Ting Yuwen, Yang Chen, Yanxue Xue, Feng Wang, Jie Shi, Yu Shi

“…Immunofluorescence staining and functional magnetic resonance imaging revealed that high-frequency DBS of the DRN could alter the activity and functional connectivity of brain regions related to addiction. …”
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Association between inflammation, reward processing, and ibuprofen-induced increases of miR-23b in astrocyte-enriched extracellular vesicles: A randomized, placebo-controlled, doub... by Kaiping Burrows, Leandra K. Figueroa-Hall, Ahlam M. Alarbi, Jennifer L. Stewart, Rayus Kuplicki, Chibing Tan, Bethany N. Hannafon, Rajagopal Ramesh, Jonathan Savitz, Sahib Khalsa, T. Kent Teague, Victoria B. Risbrough, Martin P. Paulus

“…In three separate visits, healthy participants (N = 20) received a single dose of either placebo, 200 mg, or 600 mg of ibuprofen, completed the monetary incentive delay task during functional magnetic resonance imaging, and provided a blood sample for cytokine and AEEV collection. …”
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Altered hierarchical organization between empathy and gambling networks in disordered gamblers by Hui Zhou, Hui Zhou, Yuwen He, Yuwen He, Zhen Yuan, Zhen Yuan, Yuan Zhou, Jingwen Yin, Jingwen Yin, Robin Chark, Robin Chark, Davis Ka Chio Fong, Davis Ka Chio Fong, Lawrence Hoc Nang Fong, Lawrence Hoc Nang Fong, Anise M. S. Wu, Anise M. S. Wu

“…This study aimed to address this research gap by examining the hierarchical organizational patterns, in which the differences of causal interactions of these networks between disordered gamblers and healthy controls were revealed.MethodsResting-state functional magnetic resonance imaging (fMRI) data of 32 disordered gamblers and 56 healthy controls were included in the formal analysis. …”
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A preliminary fMRI study on activiation pattern and functional reorganization of motor cortex in acute ischemic stroke patients by Fan-yong ZENG, Zhi-qiang ZHANG, Fang YANG, Jian-ping HU, Qiang XU, Guang-ming LU

“…Methods A total of 22 patients with first-ever acute ischemic stroke were included in this study. Functional magnetic resonance imaging (fMRI) was used to observe the changing of activation pattern and functional reorganization of motor cortex in finger-tapping task. …”
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Different Patterns of Neural Activity Characterize Motor Skill Performance During Acquisition and Retention by Dorsa Beroukhim-Kay, Dorsa Beroukhim-Kay, Dorsa Beroukhim-Kay, Bokkyu Kim, Bokkyu Kim, John Monterosso, John Monterosso, Rebecca Lewthwaite, Rebecca Lewthwaite, Carolee Winstein, Carolee Winstein, Carolee Winstein

“…We used whole brain analysis of functional magnetic resonance imaging (fMRI) and behavioral performance measures (i.e., time-on-target and self-efficacy) during the practice phase to determine which brain activation patterns are (1) associated with trial-by-trial tracking performance and (2) predictive of immediate no-feedback retention performance. …”
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Genuine high-order interactions in brain networks and neurodegeneration by Rubén Herzog, Fernando E. Rosas, Robert Whelan, Sol Fittipaldi, Hernando Santamaria-Garcia, Josephine Cruzat, Agustina Birba, Sebastian Moguilner, Enzo Tagliazucchi, Pavel Prado, Agustin Ibanez

“…We applied HOFC to multimodal (electroencephalography [EEG], and functional magnetic resonance imaging [fMRI]) data from patients diagnosed with behavioral variant of frontotemporal dementia (bvFTD), Alzheimer's disease (AD), and healthy controls. …”
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Multimodal classification of extremely preterm and term adolescents using the fusiform gyrus: A machine learning approach by Connor Grannis, Andy Hung, Roberto C. French, Whitney I. Mattson, Xiaoxue Fu, Kristen R. Hoskinson, H. Gerry Taylor, Eric E. Nelson

“…Method: Extremely preterm adolescents (n = 20) and full-term peers (n = 24) underwent structural and functional magnetic resonance imaging. Group differences in gray matter density, measured via voxel-based morphometry (VBM), and blood-oxygen level-dependent (BOLD) response to face stimuli were explored within the right fusiform. …”
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Pre-thrombectomy prognostic prediction of large-vessel ischemic stroke using machine learning: A systematic review and meta-analysis by Minyan Zeng, Minyan Zeng, Lauren Oakden-Rayner, Lauren Oakden-Rayner, Lauren Oakden-Rayner, Alix Bird, Alix Bird, Luke Smith, Luke Smith, Zimu Wu, Rebecca Scroop, Rebecca Scroop, Timothy Kleinig, Timothy Kleinig, Jim Jannes, Jim Jannes, Mark Jenkinson, Mark Jenkinson, Lyle J. Palmer, Lyle J. Palmer

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Hypothalamic interaction with reward-related regions during subjective evaluation of foods by Akitoshi Ogawa, Takahiro Osada, Masaki Tanaka, Akimitsu Suda, Koji Nakajima, Satoshi Oka, Koji Kamagata, Shigeki Aoki, Yasushi Oshima, Sakae Tanaka, Nobutaka Hattori, Seiki Konishi

“…In this functional magnetic resonance imaging study, the hypothalamus was parcellated into individual hypothalamic nuclei performing different autonomic functions using boundary mapping parcellation analyses. …”
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Magnetic resonance imaging parameters on lacrimal gland in thyroid eye disease: a systematic review and meta-analysis by Nicole Tsz Yan Wong, Ka Fai Kevin Yuen, Fatema Mohamed Ali Abdulla Aljufairi, Kenneth Ka Hei Lai, Zhichao Hu, Karen Kar Wun Chan, Clement Chee Yung Tham, Chi Pui Pang, Kelvin Kam Lung Chong

“…Main outcome measures include seven structural magnetic resonance imaging parameters (lacrimal gland herniation, maximum axial area, maximum coronal area, maximum axial length, maximum coronal length, maximum axial width, maximum coronal width), and three functional magnetic resonance imaging parameters (diffusion tensor imaging-fractional anisotropy, diffusion tensor imaging-apparent diffusion coefficient or mean diffusivity, diffusion-weighted imaging-apparent diffusion coefficient). …”
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Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI study and ma... by Zhaoshun Jiang, Zhaoshun Jiang, Yuxi Cai, Yuxi Cai, Songbin Liu, Songbin Liu, Pei Ye, Pei Ye, Yifeng Yang, Guangwu Lin, Shihong Li, Yan Xu, Yangjing Zheng, Zhijun Bao, Zhijun Bao, Zhijun Bao, Shengdong Nie, Weidong Gu, Weidong Gu

“…Our study was aimed at exploring the whole-brain FC patterns of all regions in DMN and the potential features as biomarkers for the prediction of DNR using machine-learning algorithms.MethodsResting-state functional magnetic resonance imaging (fMRI) was conducted before surgery on 74 patients undergoing non-cardiac surgery. …”
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Network Reconfiguration Among Cerebellar Visual, and Motor Regions Affects Movement Function in Spinocerebellar Ataxia Type 3 by Hui Chen, Limeng Dai, Yuhan Zhang, Liu Feng, Zhenzhen Jiang, Xingang Wang, Dongjing Xie, Jing Guo, Huafu Chen, Jian Wang, Chen Liu

“…In both groups, the whole-brain network topology of resting-state functional magnetic resonance imaging (rs-fMRI) was conducted using graph theory, and the relationships among network topologies, cytosine-adenine-guanine (CAG) repeats, clinical symptoms, and functional connectivity were explored in SCA3 patients using partial correlation analysis, controlling for age and sex.ResultsThe brain networks tended to be more regular with a higher clustering coefficient, local efficiency, and modularity in patients with SCA3. …”
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