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Fruit – sustaining life in the forest
Published 2012“…Most are “pioneer species”, i.e. among the first species to establish in a disturbed area, e.g. a gap in the canopy due to an old tree toppling over or after a landslide…”
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Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus.
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Experimental Investigation on Electrochemical Grinding (ECG) for Stainless Steel 316
Published 2020-01-01“…Where applied current used are (10, 20, 30, 40) A, electrolyte concentration used (100, 150, 200, 250) g/l, gap size used (0.2, 0.3, 0.4, 0.5) mm and spindle speed used (75, 150, 180, 280) rpm. …”
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Potential primary roles of glial cells in the mechanisms of psychiatric disorders
Published 2015-05-01“…Indeed, a growing body of evidence indicates that glial cells interact extensively with neurons both chemically (e.g. through neurotransmitters, neurotrophic factors and cytokines) and physically (e.g. through gap junctions), supporting a role for these cells as likely significant modifiers not only of neural function in brain development but also disease pathobiology. …”
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Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning.
Published 2010-07-01“…Using rescue of gene knockdown and in vivo calcium imaging assays, we demonstrate that the activity of Rgs3 requires its ability to interact with Galpha subunits and function as a G protein GAP. Thus, Rgs3 function is necessary for appropriate frequency and amplitude of calcium release during somitogenesis and is downstream of Wnt5 activity. …”
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Synthesis, Evaluation, and Mechanism Study of New Tepotinib Derivatives as Antiproliferative Agents
Published 2019-03-01“…A mechanism study demonstrated that <b>31e</b> induced G1 phase (First growth phase or G indicating gap) arrest, inhibited the phosphorylation of c-Met and its downstream signaling component, Akt (Protein Kinase B), and also inhibited the migration of hepatic carcinoma 97H cells.…”
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Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos
Published 2015-07-01“…In most tissues, S phase and mitosis are separated by defined G1 and G2 gap phases, but early embryogenesis involves rapid oscillations between replication and mitosis. …”
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Comparative transcriptomics reveal differential gene expression among Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms.
Published 2024-01-01“…Compared to Pvs25, gametocyte genes including PvAP2-G, PvGAP (female gametocytes), and Pvs47 (male gametocytes) were highly expressed across geographical samples.…”
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Prediction for Manufacturing Factors in a Steel Plate Rolling Smart Factory Using Data Clustering-Based Machine Learning
Published 2020-01-01“…For example, the estimation or prediction of the in-process thickness is utilized to select the control values (e.g., roll gap) in the next pass of rolling. However, adverse manufacturing conditions can interfere with accurate detection for such manufacturing factors. …”
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Transfer of a redox-signal through the cytosol by redox-dependent microcompartmentation of glycolytic enzymes at mitochondria and actin cytoskeleton
Published 2013-01-01“…Yeast two-hybrid screens, dot-blot overlay assays, and co-sedimentation assays were used to identify potential protein-protein interactions between two cytosolic GAPDH isoforms (GapC1, At3g04120; GapC2, At1g13440) from A. thaliana with the neighbouring glycolytic enzyme, fructose 1,6-bisphosphate aldolase (FBA6, At2g36460), the mitochondrial porin (VDAC3; At5g15090), and actin in vitro. …”
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MaterialsAtlas.org: a materials informatics web app platform for materials discovery and survey of state-of-the-art
Published 2022-04-01“…Herein we first survey current materials informatics web apps and then propose and develop MaterialsAtlas.org, a web-based materials informatics toolbox for materials discovery, which includes a variety of routinely needed tools for exploratory materials discovery, including material’s composition and structure validity check (e.g. charge neutrality, electronegativity balance, dynamic stability, Pauling rules), materials property prediction (e.g. band gap, elastic moduli, hardness, and thermal conductivity), search for hypothetical materials, and utility tools. …”
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On NP-hardness of the clique partition : independence number gap recognition and related problems
Published 2012“…In the other cases QCP reduces to ¯χ (G) − α(G) >0 gap recognition, with one minimum clique partition of G known.…”
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Cytotoxic and Apoptotic Activities of Prunus spinosa Trigno Ecotype Extract on Human Cancer Cells
Published 2017-09-01“…Cell cycle analysis showed a sub G1 (Gap 1 phase) peak appearance (HCT116: 35.1%; SW480: 11.6%), indicating apoptotic cell death induction that was confirmed by Annexin V assay (HCT116: 86%; SW480: 96%). …”
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How generalisable are material extrusion additive manufacturing parameter optimisation studies? A systematic review
Published 2022-11-01“…Conclusions: A wide range of studies have sought to optimise parameters (e.g., Nozzle gap height, print head velocity, filament volumetric velocity) to address dimensional quality issues in ME AM. …”
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METHODOLOGICAL PROBLEMS ON THE WAY TO INTEGRATIVE HUMAN NEUROSCIENCE
Published 2016-11-01“…As regards intradisciplinary methodological problems, we concentrate on those within neurobiology (e.g., the gap between electrical and chemical approaches to neurophysiological processes) and psychology (missing theoretical concepts). …”
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Application of Fruit By-Products and Edible Film to Cookies: Antioxidant Activity and Concentration of Oxidized LDL Receptor in Women—A First Approach
Published 2023-04-01“…A group of 12–13 healthy women (median age 36) consumed 45 g of GAP with KGAE or commercial cookies for 10 days. …”
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Arl15 upregulates the TGFβ family signaling by promoting the assembly of the Smad-complex
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Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer
Published 2018“…Distinct sequential temporal phases, Gap 1 (G1), Gap 0 (G0), Synthesis (S), Gap 2 (G2) and Mitosis (M) are negotiated through a series of check points during which the favorability of the local cellular environment is assessed, prior to replicating DNA [1]. …”
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IqgC is a potent regulator of macropinocytosis in the presence of NF1 and its loading to macropinosomes is dependent on RasG
Published 2024-01-01“…Its activity is under the control of an IQGAP-related protein, IqgC, which acts as a RasG-specific GAP (GTPase activating protein). IqgC colocalizes with the active Ras at the macropinosome membrane during its formation and for some time after the cup closure. …”
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The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections
Published 2019-01-01“…Abbreviation: AIDS: Acquired Immunodeficiency Syndrome; ATF6: Activating Transcription Factor 6; ATG6: Autophagy-specific Gene 6; BAG3: BCL Associated Athanogene 3; Bak: BCL-2-Anatagonist/Killer1; Bax; BCL-2: Associated X protein; Bcl-2: B cell Lymphoma 2x; BiP: Chaperon immunoglobulin heavy chain binding Protein; CARD: Caspase Recruitment Domain; cART: combination Antiretroviral Therapy; CCR5: C-C Chemokine Receptor type 5; CD4: Cluster of Differentiation 4; CHOP: C/EBP homologous protein; CXCR4: C-X-C Chemokine Receptor Type 4; Cyto c: Cytochrome C; DCs: Dendritic Cells; EDEM1: ER-degradation enhancing-a-mannosidase-like protein 1; ENV: Envelope; ER: Endoplasmic Reticulum; FasR: Fas Receptor;G2: Gap 2; G2/M: Gap2/Mitosis; GFAP: Glial Fibrillary Acidic Protein; GP120: Glycoprotein120; GP41: Glycoprotein41; HAND: HIV Associated Neurodegenerative Disease; HEK: Human Embryonic Kidney; HeLa: Human Cervical Epithelial Carcinoma; HIV: Human Immunodeficiency Virus; IPS-1: IFN-β promoter stimulator 1; IRE-1: Inositol Requiring Enzyme 1; IRGM: Immunity Related GTPase Family M protein; LAMP2A: Lysosome Associated Membrane Protein 2A; LC3: Microtubule Associated Light Chain 3; MDA5: Melanoma Differentiation Associated gene 5; MEF: Mouse Embryonic Fibroblast; MMP: Mitochondrial Membrane Permeabilization; Nef: Negative Regulatory Factor; OASIS: Old Astrocyte Specifically Induced Substrate; PAMP: Pathogen-Associated Molecular Pattern; PERK: Pancreatic Endoplasmic Reticulum Kinase; PRR: Pattern Recognition Receptor; Puma: P53 Upregulated Modulator of Apoptosis; RIG-I: Retinoic acid-Inducible Gene-I; Tat: Transactivator Protein of HIV; TLR: Toll-like receptor; ULK1: Unc51 Like Autophagy Activating Kinase 1; UPR: Unfolded Protein Response; Vpr: Viral Protein Regulatory; XBP1: X-Box Binding Protein 1…”
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