The effect of insulin resistance on amygdale glucose metabolism alterations in experimental Alzheimer’s disease by Ya. V. Gorina, Yu. K. Komleva, O. L. Lopatina, A. I. Chernykh, A. B. Salmina

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Mechanistic Insights into the Ameliorative Effect of Cichoriin on Diabetic Rats—Assisted with an In Silico Approach by Hany Ezzat Khalil, Miada F. Abdelwahab, Hairul-Islam Mohamed Ibrahim, Khalid A. AlYahya, Ahmed Adel Mohamed, Amira Samir Radwan, Shaimaa Waz

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Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles by Francisco Díaz-Sáez, Carla Blanco-Sinfreu, Adrià Archilla-Ortega, David Sebastian, Montserrat Romero, Maria Isabel Hernández-Alvarez, Sílvia Mora, Xavier Testar, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete, Julián Aragonés, Marta Camps, Antonio Zorzano, Anna Gumà

“…Anti-inflammatory agents recovered the insulin receptor, but not Glut4, content. Proteins enriched in Glut4 storage vesicles such as the insulin-responsive aminopeptidase (IRAP) and Syntaxin-6 as well as TBC1D4, a protein involved in the intracellular retention of Glut4 vesicles, also decreased by Nrg4 KD. …”
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Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation by Caio Yogi Yonamine, Marisa Passarelli, Claudia Kimie Suemoto, Carlos Augusto Pasqualucci, Wilson Jacob-Filho, Venâncio Avancini Ferreira Alves, Suely Kazue Nagahashi Marie, Maria Lucia Correa-Giannella, Luiz Roberto Britto, Ubiratan Fabres Machado

Subjects: “…GLUT4…”
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Activation of the NLRP3 Inflammasome Increases the IL-1β Level and Decreases GLUT4 Translocation in Skeletal Muscle during Insulin Resistance by Luan Américo-Da-Silva, Javiera Aguilera, Oscar Quinteros-Waltemath, Pablo Sánchez-Aguilera, Javier Russell, Cynthia Cadagan, Roberto Meneses-Valdés, Gina Sánchez, Manuel Estrada, Gonzalo Jorquera, Genaro Barrientos, Paola Llanos

“…Here, we evaluated the NLRP3 inflammasome components and their role in GLUT4 translocation impairment in skeletal muscle during IR. …”
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Stevioside Attenuates Insulin Resistance in Skeletal Muscle by Facilitating IR/IRS-1/Akt/GLUT 4 Signaling Pathways: An In Vivo and In Silico Approach by Abilasha Deenadayalan, Vijayalakshmi Subramanian, Vijayalakshmi Paramasivan, Vishnu Priya Veeraraghavan, Gayathri Rengasamy, Janaki Coiambatore Sadagopan, Ponnulakshmi Rajagopal, Selvaraj Jayaraman

“…Results of molecular docking analysis evidenced the higher binding affinity with IRS-1 and GLUT 4. Stevioside effectively inhibits oxidative stress and promotes glucose uptake in diabetic gastrocnemius muscles by activating IR/IRS-1/Akt/GLUT 4 pathway. …”
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Rac1 and ROCK are implicated in the cell surface delivery of GLUT4 under the control of the insulin signal mimetic diDCP-LA-PE by Ayako Tsuchiya, Takeshi Kanno, Tadashi Shimizu, Akito Tanaka, Tomoyuki Nishizaki

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Undaria pinnatifida (Wakame) Intake Ameliorates High-Fat Diet-Induced Glucose Intolerance via Promoting GLUT4 Expression and Membrane Translocation in Muscle by Motoki Imai, Fumitaka Kawakami, Mutsumi Chiba, Makoto Kanzaki, Hiroko Maruyama

“…GLUT4 membrane translocation was promoted by wakame components. …”
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Anti‐diabetic effect of andrographolide from Sambiloto herbs (Andrographis paniculata (Burm.f.) Nees) through the expression of PPARγ and GLUT‐4 in adipocytes by Novia Tri Astuti, Putri Rachma Novitasari, Raymond Tjandrawinata, Agung Endro Nugroho, Suwijiyo Pramono

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The SWGEDWGEIW from Soybean Peptides Reduces Insulin Resistance in 3T3-L1 Adipocytes by Activating p-Akt/GLUT4 Signaling Pathway by Guofu Yi, Xia Sang, Yuxia Zhu, Di Zhou, Shuibing Yang, Yue Huo, Yang Liu, Bushra Safdar, Xianyong Bu

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Anti‐diabetic effect of andrographolide from Sambiloto herbs (Andrographis paniculata (Burm.f.) Nees) through the expression of PPARγ and GLUT‐4 in adipocytes by Astuti, Novia Tri, Novitasari, Putri Rachma, Tjandrawinata, Raymond, Nugroho, Agung Endro, Pramono, Suwijiyo

“…Andrographolide was able to increase the mRNA levels of PPARγ and GLUT‐4 compared to pioglitazone with the best concentration at 5.6 μM. …”
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Effect of exercise on TRB3 and GLUT4 expression following glucose loading in chronic leptin treated rat / Siti Nurr Atika Mohd Sanif by Mohd Sanif, Siti Nurr Atika

“…Skeletal muscle tissues were collected at 0, 15, and 30 minutes respectively during the protocol for blood glucose, serum glucose, insulin, TRB3, GLUT4 protein and mRNA expression determination. …”
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Lower maternal body condition during pregnancy affects skeletal muscle structure and glut-4 protein levels but not glucose tolerance in mature adult sheep. by Costello, P, Hollis, L, Cripps, R, Bearpark, N, Patel, H, Sayer, A, Cooper, C, Hanson, M, Ozanne, SE, Green, L

α-mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPARgamma, GLUT4, and leptin expressions by Taher, Muhammad, Mohamed Amiroudine, Mohamed Zaffar Ali, Tengku Zakaria, Tengku Muhamad Faris Syafiq, Deny Susanti, Jauhari Arief Ichwan, Solachuddin, Kaderi, Mohd Arifin, Ahmed, Qamar Uddin, Zakaria, Zainul Amiruddin

“…Induction of glucose uptake and free fatty acid release by α-mangostin were accompanied by increasing mRNA expression of GLUT4 and leptin. These evidences propose that α-mangostin might be possible candidate for the effective management of obesity in future.…”
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Triple-action of the standardized antidiabetic polyherbal extract; Synacinn™ through upregulation of GLUT4 and inhibition of DPP(IV), α-amylase, and α-glucosidase activity by Ismail, Hassan Fahmi, Hashim, Zanariah, Abang Zaidel, Dayang Norulfairuz, Zainol, Siti Nurazwa, Mohamed Tap, Fatahiya, Abdul Majid, Fadzilah Adibah, Zakaria, Nor Hafizah

“…At the cellular level, Synacinn™ attenuated glucose utilization mainly by upregulating GLUT4 protein expression by 1.71 fold. Additionally, Synacinn™ is a potent inhibitor for the activity of α-amylase and α-glucosidase with IC50 of 0.467 mg/mL and 0.245 mg/mL, respectively. …”
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Triple-action of the standardized antidiabetic polyherbal extract; Synacinn™ through upregulation of GLUT4 and inhibition of DPP(IV), a-amylase, and a-glucosidase activity by Ismail, Hassan Fahmi, Hashim, Zanariah, Abang Zaidel, Dayang Norulfairuz, Zainol, Siti Nurazwa, Mohamed Tap, Fatahiya, Abdul Majid, Fadzilah Adibah, Zakaria, Nor Hafizah

“…At the cellular level, Synacinn™ attenuated glucose utilization mainly by upregulating GLUT4 protein expression by 1.71 fold. Additionally, Synacinn™ is a potent inhibitor for the activity of a-amylase and a-glucosidase with IC50 of 0.467 mg/mL and 0.245 mg/mL, respectively. …”

Serpentine Enhances Insulin Regulation of Blood Glucose through Insulin Receptor Signaling Pathway by Yinghao Wang, Guanfu Liu, Xutao Liu, Minhua Chen, Yuping Zeng, Yuyan Li, Xiaoyun Wu, Xuanjun Wang, Jun Sheng

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Effects of Polyphenols on Insulin Resistance by Gary Williamson, Katherine Sheedy

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Evaluation of the effect of interleukin-1 receptor associated kinase (IRAK) inhibitor on PPAR.γ and GLUT.4 genes expression in muscle tissueof insulin resistant mice by Beydolah Shahouzehi, Saeedeh Moinaldini, Mostafa Allahyari, Hossein Fallah

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Panax notoginseng saponins alleviate skeletal muscle insulin resistance by regulating the IRS1–PI3K–AKT signaling pathway and GLUT4 expression by Xuan Guo, Wen Sun, Guangbin Luo, Lili Wu, Guangyuan Xu, Dan Hou, Yi Hou, Xiangyu Guo, Xiaohong Mu, Lingling Qin, Tonghua Liu

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