New Observations of the Old Magnetic Nova GQ Muscae by Narloch W., Kaluzny J., Krzeminski W., Pych W., Rozyczka M., Shectman S., Thompson I. B., Tomov T.

Subjects: “…stars: individual: gq mus…”
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Conditions ($S_q$) and ($G_q$) on graded rings by La Barbiera, M

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GQ8 ARE WE SERIOUS ABOUT ENDING HUNGER? by George Kent

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Gq signaling in α cells is critical for maintaining euglycemia by Liu Liu, Diptadip Dattaroy, Katherine F. Simpson, Luiz F. Barella, Yinghong Cui, Yan Xiong, Jian Jin, Gabriele M. König, Evi Kostenis, Jefferey C. Roman, Klaus H. Kaestner, Nicolai M. Doliba, Jürgen Wess

“…In this study, we investigated the potential regulation of α cell function by G proteins of the Gq family. The use of a chemogenetic strategy allowed us to selectively activate Gq signaling in mouse α cells in vitro and in vivo. …”
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Gq Signaling in Autophagy Control: Between Chemical and Mechanical Cues by Inmaculada Navarro-Lérida, Anna M. Aragay, Alejandro Asensio, Catalina Ribas

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A Gq Biased Small Molecule Active at the TSH Receptor by Rauf Latif, Rauf Latif, Syed A. Morshed, Syed A. Morshed, Risheng Ma, Risheng Ma, Bengu Tokat, Mihaly Mezei, Terry F. Davies, Terry F. Davies

“…On screening a library of 50K molecules at 0.1,1.0 and 10 μM, we identified a novel Gq/11 agonist (named MSq1) which activated Gq/11 mediated NFAT-luciferase >4 fold above baseline and had an EC50= 8.3 × 10−9 M with only minor induction of Gαs and cAMP. …”
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Selective optogenetic control of Gq signaling using human Neuropsin by Ahmed Wagdi, Daniela Malan, Udhayabhaskar Sathyanarayanan, Janosch S. Beauchamp, Markus Vogt, David Zipf, Thomas Beiert, Berivan Mansuroglu, Vanessa Dusend, Mark Meininghaus, Linn Schneider, Bernd Kalthof, J. Simon Wiegert, Gabriele M. König, Evi Kostenis, Robert Patejdl, Philipp Sasse, Tobias Bruegmann

“…Gq proteins are one of four major classes of G proteins; optogenetic receptors for selective and repetitive activation of Gq proteins with fast kinetics are lacking. …”
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Adaptation of Gratitude Questionnaire-6 (GQ–6) in Indonesian Context by Dhanifa Veda Grimaldy, Handrix Chris Haryanto

Subjects: “…gratitude questionnaire-6 (gq-6)…”
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Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement by Youichi Iwai, Katsuya Ozawa, Kazuko Yahagi, Tsuneko Mishima, Sonam Akther, Camilla Trang Vo, Camilla Trang Vo, Ashley Bomin Lee, Mika Tanaka, Mika Tanaka, Shigeyoshi Itohara, Hajime Hirase, Hajime Hirase

“…To address this, transgenic mice with astrocytic expression of the optogenetic Gq-type GPCR, Optoα1AR, were established, in which transient Ca2+ elevations similar to those in wild type mice were induced by brief blue light illumination. …”
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Loss of gq/11 genes does not abolish melanopsin phototransduction. by Kylie S Chew, Tiffany M Schmidt, Alan C Rupp, Paulo Kofuji, Jeffrey M Trimarchi

“…However, the exact identity of the Gq/11 gene involved in this process has remained elusive. …”
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Opsoclonus myoclonus syndrome associated with GQ1b antibodies. by Morales-Briceño, H, Rodríguez-Violante, M, Cervantes-Arriaga, A, Irani, SR, Lees, A, Silveira-Moriyama, L

Tetrameric glycoprotein complex gH/gL/gQ1/gQ2 is a promising vaccine candidate for human herpesvirus 6B. by Bochao Wang, Kouichi Hara, Akiko Kawabata, Mitsuhiro Nishimura, Aika Wakata, Lidya Handayani Tjan, Anna Lystia Poetranto, Chisato Yamamoto, Yasunari Haseda, Taiki Aoshi, Lisa Munakata, Ryo Suzuki, Masato Komatsu, Ryuko Tsukamoto, Tomoo Itoh, Chikako Nishigori, Yasuyuki Saito, Takashi Matozaki, Yasuko Mori

“…The glycoprotein complex gH/gL/gQ1/gQ2 (called 'tetramer of HHV-6B') on the virion surface is a viral ligand for its cellular receptor human CD134, and their interaction is thus essential for virus entry into the cells. …”
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Clinical Characterization of Anti-GQ1b Antibody Syndrome in Childhood by Lianhong Cai, Zhanqi Hu, Jianxiang Liao, Siqi Hong, Lingyu Kong, Li Chen, Yetao Luo, Tingsong Li, Li Jiang

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Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila by Sophie Himmelreich, Ikuo Masuho, Jacob A. Berry, Courtney MacMullen, Nickolas K. Skamangas, Kirill A. Martemyanov, Ronald L. Davis

“…However, the Damb receptor uniquely activates Gq to mobilize Ca2+ signaling with greater efficiency and dopamine sensitivity. …”
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Molecular mechanism of muscarinic acetylcholine receptor M3 interaction with Gq by Donghee Ham, Asuka Inoue, Jun Xu, Yang Du, Ka Young Chung

“…Abstract Muscarinic acetylcholine receptor M3 (M3) and its downstream effector Gq/11 are critical drug development targets due to their involvement in physiopathological processes. …”
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Adipocyte Gq signaling is a regulator of glucose and lipid homeostasis in mice by Takefumi Kimura, Sai P. Pydi, Lei Wang, Dhanush Haspula, Yinghong Cui, Huiyan Lu, Gabriele M. König, Evi Kostenis, Gregory R. Steinberg, Oksana Gavrilova, Jürgen Wess

“…Here the authors report that adipocyte Gq signaling functions as a regulator of lipolysis and systemic glucose and lipid homeostasis in mice, suggesting that agents able to stimulate this pathway may prove useful as antidiabetic drugs.…”
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Cryo-EM structure of the human histamine H1 receptor/Gq complex by Ruixue Xia, Na Wang, Zhenmei Xu, Yang Lu, Jing Song, Anqi Zhang, Changyou Guo, Yuanzheng He

“…Here, the authors present the cryo-EM structure of histamine-bound H1R/Gq complex and propose a mechanism of ligand induced receptor activation.…”
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Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX by Jiajia Ma, Claire A Scott, Ying Na Ho, Harsha Mahabaleshwar, Katherine S Marsay, Changqing Zhang, Christopher KJ Teow, Ser Sue Ng, Weibin Zhang, Vinay Tergaonkar, Lynda J Partridge, Sudipto Roy, Enrique Amaya, Tom J Carney

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JNK Cascade-Induced Apoptosis—A Unique Role in GqPCR Signaling by Guy Nadel, Galia Maik-Rachline, Rony Seger

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Author Correction: Selective optogenetic control of Gq signaling using human Neuropsin by Ahmed Wagdi, Daniela Malan, Udhayabhaskar Sathyanarayanan, Janosch S. Beauchamp, Markus Vogt, David Zipf, Thomas Beiert, Berivan Mansuroglu, Vanessa Dusend, Mark Meininghaus, Linn Schneider, Bernd Kalthof, J. Simon Wiegert, Gabriele M. König, Evi Kostenis, Robert Patejdl, Philipp Sasse, Tobias Bruegmann

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