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Roles of Heterotrimeric GTP-Binding Proteins in the Progression of Heart Failure
Published 2011-01-01“…These agonists stimulate seven transmembrane-spanning receptors that are coupled to heterotrimeric GTP-binding proteins (G proteins). Using specific pharmacological tools to assess the involvement of G protein signaling pathways, we have revealed that α subunit of Gq (Gαq) activates Ca2+-dependent hypertrophic signaling through diacylglycerol-activated transient receptor potential canonical (TRPC) channels (TRPC3 and TRPC6: TRPC3/6). …”
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Expression Analysis of the Small GTP-Binding Protein Rac in Pterygium
Published 2023-12-01“…Objectives: To determine the roles of small GTP-binding proteins Rac1, Rac2, and Rac3 expression in pterygial tissue and to compare these expressions with normal conjunctival tissue. …”
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Biochemical and physiological characterization of the GTP-binding protein Obg of <it>Mycobacterium tuberculosis</it>
Published 2011-02-01“…<p>Abstract</p> <p>Background</p> <p>Obg is a highly conserved GTP-binding protein that has homologues in bacteria, archaea and eukaryotes. …”
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Involvement of a small GTP binding protein in HIV-1 release
Published 2005-08-01“…A crucial step in the reorganisation of the actin cytoskeleton is the engagement of various different GTP binding proteins. We have thus studied the involvement of GTP-binding proteins in the final steps of the HIV-1 viral replication cycle.…”
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Molecular Characterization of GTP Binding Protein Gene in Dermatophyte Pathogen Trichophyton rubrum
Published 2006-08-01“…The amino acid sequence of the encoded protein was about 64% identical to the sequence of GTP binding protein from other fungi. In summary, we have cloned the first GTP binding protein of dermatophytes and characterized it as a member of this gene family in other eukaryotic cells.…”
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Tissue‐specific expression differences in Ras‐related GTP‐binding proteins in male rats
Published 2024-02-01Subjects: Get full text
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The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein Arf
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The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes.
Published 2015-01-01“…Taken together, we conclude that Nemp1 represents a new type of RanGTP-binding protein.…”
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A host small GTP-binding protein ARL8 plays crucial roles in tobamovirus RNA replication.
Published 2011-12-01“…Here, we show that a small GTP-binding protein ARL8, along with TOM1, is co-purified with a FLAG epitope-tagged ToMV 180K replication protein from solubilized membranes of ToMV-infected tobacco (Nicotiana tabacum) cells. …”
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GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development
Published 2022-12-01“…Here, we report a novel gene, <i>gtpbp1l</i> (<i>GTP-binding protein 1-like</i>), that regulates vascular development in zebrafish. …”
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GTP Binding Protein Gtr1 Cooperating with ASF1 Regulates Asexual Development in <i>Stemphylium eturmiunum</i>
Published 2022-07-01Subjects: “…GTP binding protein Gtr1…”
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Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis.
Published 2014-01-01“…Septins (SEPTs) form a family of GTP-binding proteins implicated in cytoskeleton and membrane organization, cell division and host/pathogen interactions. …”
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Integrated Analysis of Genomic and Transcriptomic Profiles Identified the Role of GTP Binding Protein-4 (GTPBP4) in Breast Cancer
Published 2022-06-01“…Purpose: To explore the significance of GTP-binding protein 4 (GTPBP4) in breast cancer.Methods: Firstly, GTPBP4 expression analysis was performed in TIMER and UALCAN databases. …”
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Mutations in GTP binding protein Obg of Mycoplasma synoviae vaccine strain MS-H: implications in temperature-sensitivity phenotype.
Published 2013-01-01“…Comparison of the complete genome sequence of MS-H, its parent strain 86079/7NS and two non-temperature sensitive (ts (-)) reisolates of MS-H revealed a mutation in a highly conserved domain of GTP binding protein Obg of MS-H, with reversion in ts (-) MS-H reisolates. …”
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Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis
Published 2021-07-01“…Purpose: This study aimed to confirm the association between developmentally regulated GTP-binding protein 2 (DRG2) expression and docetaxel-induced apoptosis and to determine whether prostate cancer responses to docetaxel treatment differ with DRG2 expression. …”
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Involvement of pertussis toxin-sensitive and -insensitive GTP-binding proteins in luteinizing hormone exocytosis distal to second messenger generation.
Published 1992“…Inhibition of luteinizing hormone (LH) exocytosis by guanosine 5'-[gamma-thio]triphosphate (GTP gamma S) in permeabilized pituitary cells has indicated the involvement of one or more GTP-binding proteins in the exocytotic mechanism distal to second messenger generation. …”
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A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network
Published 2013-01-01“…Using siRNA knockdown experiments, we find that the GTP-binding protein, Arfrp1, and the clathrin adaptor complex 1 (AP-1) are required for Vangl2 transport from the TGN. …”
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Droj2 Facilitates Somatosensory Neurite Sculpting via GTP-Binding Protein Arf102F in <i>Drosophila</i>
Published 2023-08-01“…We further show that Arf102F, a GTP-binding protein previously implicated in protein trafficking, serves downstream of Droj2 to govern neurite pruning of C4da sensory neurons. …”
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Expression of ATP/GTP Binding Protein 1 Has Prognostic Value for the Clinical Outcomes in Non-Small Cell Lung Carcinoma
Published 2020-12-01“…ATP/GTP binding protein 1 (<i>AGTPBP1</i>) encodes a crucial protein, cytosolic carboxypeptidase 1 (CCP1), which plays a role in modulating the polyglutamylation of tubulin and has been studied in degenerative diseases. …”
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