-
181
A splice variant of PGRP-LC required for expression of antimicrobial peptides in Anopheles gambiae
Published 2007“…PGRP-LC, one of seven members of this family in the malaria vector Anopheles gambiae produced several spliced variants. Here we show that PGRP-LC, and not other members of the PGRP family nor the six members of the Gram-negative binding protein families, is required for the expression of antimicrobial peptide genes (such as CEC1 and GAMI) under the control of the Imd-Rel2 pathway in an A. gambiae cell line, 4a3A. …”
Journal article -
182
Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study
Published 2021“…<br> <strong>Methods</strong> We determined the lethal concentration 50 for ivermectin in colonized Anopheles gambiae; then we used chemical inhibitors and inducers of xenobiotic pumps and cytochrome P450 enzymes in combination with ivermectin to probe the mechanism of ivermectin detoxification. …”
Journal article -
183
A national DNA bank in The Gambia, West Africa, and genomic research in developing countries.
Published 2004Journal article -
184
Absence of crisis form factor in subjects immune to Plasmodium falciparum in The Gambia, West Africa.
Published 1987Journal article -
185
Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes.
Published 2001“…In this report we describe the cloning of the Anopheles gambiae gene encoding the laminin gamma 1 polypeptide and follow its expression during mosquito development. …”
Journal article -
186
Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae.
Published 2005“…We show that, in the malaria vector Anopheles gambiae, expression of Cecropin 1 is regulated by REL2, an NF-kappaB-like transcription factor orthologous to Drosophila Relish. …”
Journal article -
187
Foul wind, spirits and witchcraft : illness conceptions and health-seeking behaviour for malaria in the Gambia
Published 2015“…<strong>Background</strong> As the disease burden in the Gambia has reduced considerably over the last decade, heterogeneity in malaria transmission has become more marked, with infected but asymptomatic individuals maintaining the reservoir. …”
Journal article -
188
Impact of personality traits on work performance in tidal paddy production in the Gambia: a review
Published 2017“…Improve rice productivity in the Gambia is essential for stakeholders as it is main actor in achieving food self-sufficiency and security. …”
Get full text
Article -
189
Vehicle emission control measures for environmental sustainability (pollution control) regulation: case of the Gambia
Published 2021“…Reports in 2018 showed that the Gambia ranked 170 ($22.5 Million) in vehicleimports in the world. …”
Get full text
Article -
190
Is chronic malnutrition associated with an increase in malaria incidence? A cohort study in children aged under 5 years in rural Gambia
Published 2018-08-01Subjects: Get full text
Article -
191
O Conflito de Casamansa e as Relações de Poderna Senegâmbia: Senegal, Guiné-Bissau e Gâmbia
Published 2019-11-01Subjects: Get full text
Article -
192
Introducing assisted reproductive technologies in The Gambia, a survey on the perspectives of Gambian healthcare professionals and medical students
Published 2023-02-01Subjects: Get full text
Article -
193
Impact of the COVID-19 pandemic on the coverage and timeliness of routine childhood vaccinations in the Gambia, 2015–2021
Published 2023-12-01“…This study examined coverage and timeliness of routine childhood immunisation during the pandemic in The Gambia, a country with an immunisation system considered robust.Methods We obtained prospective birth cohort data of 57 286 children in over 300 communities in two health and demographic surveillance system sites, including data from the pre-pandemic period (January 2015–February 2020) and the three waves of the pandemic period (March 2020–December 2021). …”
Get full text
Article -
194
Losing identity: structural diversity of transposable elements belonging to different classes in the genome of <it>Anopheles gambiae</it>
Published 2012-06-01Subjects: Get full text
Article -
195
Clinical manifestations and outcomes of severe malaria in adult patients admitted to a tertiary hospital in the Gambia
Published 2022-09-01Subjects: Get full text
Article -
196
Identification of morphological and chemical markers of dry- and wet-season conditions in female Anopheles gambiae mosquitoes
Published 2014-06-01“…Abstract Background Increased understanding of the dry-season survival mechanisms of Anopheles gambiae in semi-arid regions could benefit vector control efforts by identifying weak links in the transmission cycle of malaria. …”
Get full text
Article -
197
Prevalence of five treatable sexually transmitted infections among women in Lower River region of The Gambia
Published 2023-07-01Subjects: Get full text
Article -
198
Perceptions and acceptability of the controlled human malaria infection (CHMI) model in The Gambia: a qualitative study
Published 2023-05-01“…This qualitative study assessed the perception and acceptability of such studies in The Gambia following the first CHMI study conducted in the country in March–May 2018. …”
Get full text
Article -
199
Continuous exposure to <it>Plasmodium </it>results in decreased susceptibility and transcriptomic divergence of the <it>Anopheles gambiae </it>immune system
Published 2007-12-01“…</p> <p>Results</p> <p>In the present study we have addressed the effect of a continuous <it>Plasmodium berghei </it>infection on the resistance to infection and global gene expression in <it>Anopheles gambiae</it>.</p> <p>Exposure of <it>A. gambiae </it>to <it>P. berghei</it>-infected blood and infection for 16 generations resulted in a decreased susceptibility to infection, altered constitutive expression levels for approximately 2.4% of the mosquito's total transcriptome and a lower basal level of immune genes expression, including several anti-<it>Plasmodium </it>factors. …”
Get full text
Article -
200
Dynamic miRNA-mRNA interactions coordinate gene expression in adult Anopheles gambiae.
Published 2020-04-01“…It also provides a roadmap for additional studies focused on regulatory functions of miRNAs in Anopheles gambiae.…”
Get full text
Article