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1341
Evolutionary trade-offs associated with copy number variations in resistance alleles in Culex pipiens mosquitoes
Published 2022-12-01“…As a response, the same amino acid substitution in the ace-1 gene (G119S), conferring resistance to both insecticides, has been selected independently in many mosquito species. In Anopheles gambiae, it has recently been shown that the G119S mutation is actually part of homogeneous duplications that associate multiple resistance copies of the ace-1 gene. …”
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1342
The Crystal Structure of <i>Bacillus thuringiensis</i> Tpp80Aa1 and Its Interaction with Galactose-Containing Glycolipids
Published 2022-12-01“…Here, we demonstrate an expanded target range, showing Tpp80Aa1 is also active against the larvae of <i>Anopheles gambiae</i> and <i>Aedes aegypti</i> mosquitoes. We report the first crystal structure of Tpp80Aa1 at a resolution of 1.8 Å, which shows Tpp80Aa1 consists of two domains: an N-terminal β-trefoil domain resembling a ricin B lectin and a C-terminal putative pore-forming domain sharing structural similarity with the aerolysin family. …”
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1343
Enhanced dimensionality reduction methods for classifying malaria vector dataset using decision tree
Published 2021“…The classifier uses Decision tree on the reduced mosquito anopheles gambiae dataset to enhance the accuracy and scalability in the gene expression analysis. …”
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1344
Anopheles larval habitats seasonality and environmental factors affecting larval abundance and distribution in Arjo-Didessa sugar cane plantation, Ethiopia
Published 2023-11-01“…Results The study revealed that Anopheles gambiae sensu lato (s.l.) was the most predominant 4197(57%) vector species, followed by Anopheles coustani complex 2388 (32.8%). …”
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1345
Evaluation du paludisme dans une cohorte randomisée d’enfants (6 mois- 6 ans) au niveau de deux sites de transmission différente au cours de la saison 2001: Sotuba et Donéguébougou...
Published 2014-04-01“…Donéguébougou pourrait être un bon site pour l’essai vaccinal de phase I. Les espèces An. gambiae sl, et An. funestus étaient les principaux vecteurs de la transmission.…”
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1346
Higher temperature accelerates the aging-dependent weakening of the melanization immune response in mosquitoes.
Published 2024-01-01“…Here, we evaluated the independent and combined effects of temperature (27°C, 30°C and 32°C) and aging (1, 5, 10 and 15 days old) on the melanization immune response of the adult female mosquito, Anopheles gambiae. Using a spectrophotometric assay that measures phenoloxidase activity (a rate limiting enzyme) in hemolymph, and therefore, the melanization potential of the mosquito, we discovered that the strength of melanization decreases with higher temperature, aging, and infection. …”
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1347
Shifting suitability for malaria vectors across Africa with warming climates
Published 2009-05-01“…</p> <p>Methods</p> <p>I derive spatially explicit estimates of human populations living in regions newly suitable climatically for populations of two key <it>Anopheles gambiae </it>vector complex species in Africa over the coming 50 years, based on ecological niche model projections over two global climate models, two scenarios of climate change, and detailed spatial summaries of human population distributions.…”
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1348
Comparative genomic analysis of Drosophila melanogaster and vector mosquito developmental genes.
Published 2011-01-01“…Genome sequencing projects have presented the opportunity for analysis of developmental genes in three vector mosquito species: Aedes aegypti, Culex quinquefasciatus, and Anopheles gambiae. A comparative genomic analysis of developmental genes in Drosophila melanogaster and these three important vectors of human disease was performed in this investigation. …”
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1349
Subsidio para a história do paludismo em S. Tomé. Considerações sobre uma epidemia.
Published 1996-09-01“…Between 1946 and 1967, localities were stratified according to their endemicity, the major vectorial species (Anopheles gambiae sp.) were identified and the parasitological indices were calculated. …”
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1350
The Plasmodium falciparum cell-traversal protein for ookinetes and sporozoites as a candidate for preerythrocytic and transmission-blocking vaccines.
Published 2016“…Notably, monoclonal antibodies against PfCelTOS strongly inhibited oocyst development of P. falciparum and Plasmodium berghei expressing PfCelTOS in Anopheles gambiae mosquitoes. Taken together, our results demonstrate that anti-CelTOS responses elicited by vaccination or passive immunization can inhibit sporozoite and ookinete infection and impair vector transmission.…”
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1351
Viral vectored transmission blocking vaccines against Plasmodium falciparum
Published 2010“…Antibodies raised against Pfs48/45, Pfs230 Region C, PfHAP2, and Anopheles gambiae Alanyl Aminopeptidase N1 (AgAPN1) proteins reduce transmission i.e. have transmission blocking activity [1–5]. …”
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1352
Requirements for effective malaria control with homing endonuclease genes.
Published 2011“…Our model, combined with currently available data, indicates that populations of Anopheles gambiae could be eliminated by releasing 2-3 HEGs targeting female fertility genes, or a driving-Y chromosome that is transmitted to 75-96% of progeny. …”
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1353
Evolution and assembly of Anopheles aquasalis's immune genes: primary malaria vector of coastal Central and South America and the Caribbean Islands
Published 2023-07-01“…Comparatively, the American anophelines possess fewer genes than Anopheles gambiae s. s., the most dangerous African vector. …”
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1354
The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes
Published 2022-09-01“…Here, we conducted RNA sequencing in the African malaria mosquito, Anopheles gambiae, and discovered that an infection upregulates multiple components of the immune deficiency (IMD) and c-Jun N-terminal kinase (JNK) pathways in the heart with periostial haemocytes. …”
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1355
Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy
Published 2021-04-01“…High intensity of resistance to the discriminating concentration (DC), 5× DC, and 10× DC of pyrethroids was observed in both <i>Anopheles funestus</i> and <i>Anopheles gambiae</i> in Mayuge and Busia leading to significant reduced performance of long-lasting insecticidal nets (LLINs) including the piperonyl butoxide (PBO)-based nets (Olyset Plus). …”
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1356
Mosquito host-seeking diel rhythm and chemosensory gene expression is affected by age and Plasmodium stages
Published 2022-11-01“…Abstract Malaria parasites can affect vector-related behaviours, increasing transmission success. Using Anopheles gambiae and Plasmodium falciparum, we consider the effect of interaction between infection stage and vector age on diel locomotion in response to human odour and the expression of antennal chemosensory genes. …”
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1357
Comparative genomic analysis of malaria mosquito vector-associated novel pathogen Elizabethkingia anophelis
Published 2014“…We showed that unlike the hospital-isolated pathogen E. meningoseptica ATCC 12535 strain, the hospital-isolated E. anophelis strains have genome content and organization similar to the E. anophelis Ag1 and R26 strains isolated from the midgut microbiota of the malaria mosquito vector Anopheles gambiae. Both the core- and accessory genomes of Elizabethkingia spp. possess genes conferring antibiotic resistance and virulence. …”
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1358
Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles.
Published 2023-06-01“…From pyrethroid-resistant field-derived Anopheles gambiae s.l. mosquitoes, we established resistant (RES) and susceptible (SUS) colonies by either selection for, or loss of insecticide resistance. …”
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1359
The interaction between permethrin exposure and malaria infection affects the host-seeking behaviour of mosquitoes
Published 2019-03-01“…Results In this laboratory setting, sub-lethal exposure to permethrin inhibited the blood-seeking behaviour of Anopheles gambiae mosquitoes for almost 48 h. Although infection by malaria did not affect the irritancy of the mosquitoes to permethrin at either the developmental stage or the infectious stage, both stages of infection shortened the duration of inhibition of blood-seeking. …”
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1360
A resistência aos inseticidas e sua medida em mosquitos
Published 1972-04-01“…Menciona os processos de controle biológico por machos esterilizados, parasitas e predadores, e lembra que as duas campanhas contra insetos de importância sanitária que tiveram maior êxito no Brasil, a do Aedes aegypti e a do Anopheles gambiae, utilizaram táticas ecléticas, como é hoje preconizado pelos cntomologistas de vanguarda, no que se convencionou chamar de luta integrada.…”
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