Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis by Michael Papanicolaou, Amelia L. Parker, Michelle Yam, Elysse C. Filipe, Sunny Z. Wu, Jessica L. Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N. Skhinas, Morghan C. Lucas, David Herrmann, Max Nobis, Brooke A. Pereira, Andrew M. K. Law, Lesley Castillo, Kendelle J. Murphy, Anaiis Zaratzian, Jordan F. Hastings, David R. Croucher, Elgene Lim, Brian G. Oliver, Fatima Valdes Mora, Benjamin L. Parker, David Gallego-Ortega, Alexander Swarbrick, Sandra O’Toole, Paul Timpson, Thomas R. Cox

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CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan by Claire Vennin, Pauline Mélénec, Romain Rouet, Max Nobis, Aurélie S. Cazet, Kendelle J. Murphy, David Herrmann, Daniel A. Reed, Morghan C. Lucas, Sean C. Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T. Grey, Andrew Da Silva, Wilfred Leung, Australian Pancreatic Genome Initiative (APGI), Suresh Mathivanan, Yingxiao Wang, Anthony W. Braithwaite, Daniel Christ, Ales Benda, Ashleigh Parkin, Phoebe A. Phillips, John M. Whitelock, Anthony J. Gill, Owen J. Sansom, David R. Croucher, Benjamin L. Parker, Marina Pajic, Jennifer P. Morton, Thomas R. Cox, Paul Timpson

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Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains by Amanda Khoury, Joanna Achinger-Kawecka, Saul A. Bert, Grady C. Smith, Hugh J. French, Phuc-Loi Luu, Timothy J. Peters, Qian Du, Aled J. Parry, Fatima Valdes-Mora, Phillippa C. Taberlay, Clare Stirzaker, Aaron L. Statham, Susan J. Clark

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Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer by Qian Du, Saul A. Bert, Nicola J. Armstrong, C. Elizabeth Caldon, Jenny Z. Song, Shalima S. Nair, Cathryn M. Gould, Phuc-Loi Luu, Timothy Peters, Amanda Khoury, Wenjia Qu, Elena Zotenko, Clare Stirzaker, Susan J. Clark

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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer by Joanna Achinger-Kawecka, Fatima Valdes-Mora, Phuc-Loi Luu, Katherine A. Giles, C. Elizabeth Caldon, Wenjia Qu, Shalima Nair, Sebastian Soto, Warwick J. Locke, Nicole S. Yeo-Teh, Cathryn M. Gould, Qian Du, Grady C. Smith, Irene R. Ramos, Kristine F. Fernandez, Dave S. Hoon, Julia M. W. Gee, Clare Stirzaker, Susan J. Clark

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Author Correction: Diagnosis of fusion genes using targeted RNA sequencing by Erin E. Heyer, Ira W. Deveson, Danson Wooi, Christina I. Selinger, Ruth J. Lyons, Vanessa M. Hayes, Sandra A. O’Toole, Mandy L. Ballinger, Devinder Gill, David M. Thomas, Tim R. Mercer, James Blackburn

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DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response by Louise A. Baldwin, Nenad Bartonicek, Jessica Yang, Sunny Z. Wu, Niantao Deng, Daniel L. Roden, Chia-Ling Chan, Ghamdan Al-Eryani, Damien J. Zanker, Belinda S. Parker, Alexander Swarbrick, Simon Junankar

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Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer by Fátima Valdés-Mora, Cathryn M. Gould, Yolanda Colino-Sanguino, Wenjia Qu, Jenny Z. Song, Kylie M. Taylor, Fabian A. Buske, Aaron L. Statham, Shalima S. Nair, Nicola J. Armstrong, James G. Kench, Kenneth M. L. Lee, Lisa G. Horvath, Minru Qiu, Alexei Ilinykh, Nicole S. Yeo-Teh, David Gallego-Ortega, Clare Stirzaker, Susan J. Clark

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Diagnosis of fusion genes using targeted RNA sequencing by Erin E. Heyer, Ira W. Deveson, Danson Wooi, Christina I. Selinger, Ruth J. Lyons, Vanessa M. Hayes, Sandra A. O’Toole, Mandy L. Ballinger, Devinder Gill, David M. Thomas, Tim R. Mercer, James Blackburn

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A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features by Andre L. M. Reis, Ira W. Deveson, Ted Wong, Bindu Swapna Madala, Chris Barker, James Blackburn, Esteban Marcellin, Tim R. Mercer

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Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNA methylation profiling by Timothy J. Peters, Braydon Meyer, Lauren Ryan, Joanna Achinger-Kawecka, Jenny Song, Elyssa M. Campbell, Wenjia Qu, Shalima Nair, Phuc Loi-Luu, Phillip Stricker, Elgene Lim, Clare Stirzaker, Susan J. Clark, Ruth Pidsley

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ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling by Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Gunther Leuckx, Luc Baeyens, Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew V. Biankin, Jianmin Wu, Ilse Rooman

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Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype by Fátima Valdés-Mora, Robert Salomon, Brian Stewart Gloss, Andrew Man Kit Law, Jeron Venhuizen, Lesley Castillo, Kendelle Joan Murphy, Astrid Magenau, Michael Papanicolaou, Laura Rodriguez de la Fuente, Daniel Lee Roden, Yolanda Colino-Sanguino, Zoya Kikhtyak, Nona Farbehi, James Ronald William Conway, Neblina Sikta, Samantha Richelle Oakes, Thomas Robert Cox, Seán Ignatius O’Donoghue, Paul Timpson, Christopher John Ormandy, David Gallego-Ortega

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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients by Romain Rouet, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L. Burnett, Simon H. J. Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J. Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C. Goodnow, Stuart G. Turville, William D. Rawlinson, Rowena A. Bull, Alastair G. Stewart, Philip M. Hansbro, Daniel Christ

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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling by Le May Thai, Liam O’Reilly, Saskia Reibe-Pal, Nancy Sue, Holly Holliday, Lewin Small, Carsten Schmitz-Peiffer, Rama Dhenni, Vicky Wang-Wei Tsai, Nicholas Norris, Belinda Yau, Xuan Zhang, Kailun Lee, Chenxu Yan, Yan-Chuan Shi, Melkam A. Kebede, Robert Brink, Gregory J. Cooney, Katharine M. Irvine, Samuel N. Breit, Tri G. Phan, Alexander Swarbrick, Trevor J. Biden

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Corrigendum to “Insulin controls food intake and energy balance via NPY neurons” [Mol Metabol 6 (2017) 574–584] by Kim Loh, Lei Zhang, Amanda Brandon, Qiaoping Wang, Denovan Begg, Yue Qi, Melissa Fu, Rishikesh Kulkarni, Jonathan Teo, Paul Baldock, Jens C. Bruning, Gregory Cooney, Greg G. Neely, Herbert Herzog

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Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling by Lei Zhang, Chi Kin Ip, I-Chieh J. Lee, Yue Qi, Felicia Reed, Tim Karl, Jac Kee Low, Ronaldo F. Enriquez, Nicola J. Lee, Paul A. Baldock, Herbert Herzog

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Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis by Simon A. Hardwick, Wendy Y. Chen, Ted Wong, Bindu S. Kanakamedala, Ira W. Deveson, Sarah E. Ongley, Nadia S. Santini, Esteban Marcellin, Martin A. Smith, Lars K. Nielsen, Catherine E. Lovelock, Brett A. Neilan, Tim R. Mercer

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Osteoglycin, a novel coordinator of bone and glucose homeostasis by N.J. Lee, N. Ali, L. Zhang, Y. Qi, I. Clarke, R.F. Enriquez, M. Brzozowska, I.C. Lee, M.J. Rogers, D.R. Laybutt, J.R. Center, P.A. Baldock, H. Herzog

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Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases by Wing-Hong Jonathan Ho, Andrew M. K. Law, Etienne Masle-Farquhar, Lesley E. Castillo, Amanda Mawson, Moira K. O’Bryan, Christopher C. Goodnow, David Gallego-Ortega, Samantha R. Oakes, Christopher J. Ormandy

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