Fatigue is not a specific symptom in patients with primary biliary cirrhosis. por Björnsson, E, Simren, M, Olsson, R, Chapman, R

“…Limited data exist on comparison with fatigue in the general population and comparison with patients with other chronic gastrointestinal disorders are lacking. METHOD: We enrolled 96 patients with PBC (87 females); mean age 63 (range 34-65) who completed the Fatigue Impact Scale (FIS). …”

Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases por Samsel, Anthony, Seneff, Stephanie

“…Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease. …”
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Marketing medicines: charting the rise of modern therapeutics through a systematic review of adverts in UK medical journals (1950–1980) por Green, A, Haddad, P, Aronson, J

“…</p> <p><h4>Methods</h4></p> <p>We systematically reviewed advertisements promoting drugs for specific therapeutic areas, namely central nervous system disorders (anxiety and sleep disorders, depression, psychoses, and Parkinson's disease), respiratory disorders, cardiovascular disorders, and gastrointestinal disorders. We examined about 800 issues of the British Medical Journal (1950–1980) and about 150 issues of World Medicine (1965–1984).…”

A cross-sectional study on medications used by pregnant women: any safety concern? por Siew, S.C., Jey, V.K., Omar, S.Z.

“…The classes of medications commonly used by the pregnant respondents were analgesics (26.8% of the respondents), followed by cough and cold medications (18.6%) and medications for gastrointestinal disorders (11.8%). Among the 697 medications used by the respondents during pregnancy, 0.1% was classified under pregnancy safety category A, 51.8% were under category B, 14.3% were under category C, 0.7% under category D and 0.1% under category X. …”
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Phase I dose-escalation study of the safety, pharmacokinetics, and pharmacodynamics of the MEK inhibitor RO4987655 (CH4987655) in patients with advanced solid tumors. por Leijen, S, Middleton, MR, Tresca, P, Kraeber-Bodéré, F, Dieras, V, Scheulen, M, Gupta, A, Lopez-Valverde, V, Xu, Z, Rueger, R, Tessier, J, Shochat, E, Blotner, S, Naegelen, V, Schellens, J, Eberhardt, W

“…Rash-related toxicity (91.8%) and gastrointestinal disorders (69.4%) were the most frequent adverse events. …”

T lymphocyte subsets in inflammatory bowel disease: peripheral blood. por Selby, W, Jewell, D

“…Eighteen normal subjects and 16 patients with a variety of non-inflammatory gastrointestinal disorders were studied as controls. No significant differences were found between patient and control groups in the proportions of circulating T lymphocytes or their subsets. …”

Gastroprotective activity and mechanism of novel dichlorido-zinc(II)-4-(2-(5-methoxybenzylideneamino)ethyl)piperazin-1-iumphenolate complex on ethanol-induced gastric ulceration por Salga, Muhammad Saleh, Ali, Hapipah Mohd, Abdulla, Mahmood Ameen, Abdelwahab, Siddig Ibrahim

“…Zinc complexes were reported to have anti-ulcer activity and used as drug for the treatment of gastrointestinal disorders. A novel compound dichlorido-zinc(II)-4-(2-(5-methoxybenzylidene amino)ethyl)piperazin-1-iumphenolate (ZnHMS) was synthesized, characterized and evaluated for its gastroprotective activity against ethanol-induced ulcer in rats. …”
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The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo: Possible involvement of indirect antioxidan... por Abdelwahab, S.I., Mohan, S., Abdulla, M.A., Sukari, M.A., Abdul, A.B., Taha, M.M., Syam, S., Ahmad, S., Lee, K.H.

“…Mansf. has been used for the treatment of gastrointestinal disorders including peptic ulcer. AIM OF THE STUDY: The current study aimed to investiagte the anti-ulcer activities of methanolic extract of Boesenbergia rotunda (MEBR) and its main active compound, pinostrobin on ethanol-induced ulcer in rats. …”

The commensal microbiota exacerbate infectious colitis in stressor-exposed mice por Galley, Jeffrey D., Ahmer, Brian M.M., Bailey, Michael T., Parry, Nicola, Fox, James G

“…This study demonstrates that the commensal microbiota directly contribute to excessive inflammatory responses to C. rodentium during stressor exposure, and may help to explain why gastrointestinal disorders are worsened during stressful experiences. …”
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Dynamic cardiovagal response to motion sickness: A point-process heart rate variability study por Brown, Emery N., Barbieri, Riccardo, Napadow, Vitaly, LaCount, Lauren T., Kuo, B., Park, K., Kim, J.

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Effects of Xiang Sha Yang Wei Wan on ethanol-induced gastric ulcer in sprague dawley rats: A histological study por Al-Qaraghuli , Ahmed S, Abdel Wahab, Emad M N, Al-Ani, Imad Matloub Dally, Faisal, Ghasak Ghazi

“…Introduction: Xiang Sha Yang Wei Wan (XSYWW) is a Chinese traditional medicine that is used for gastrointestinal disorders, specifically gastric ulcer in many countries of South-East Asia. …”
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Detailed assessment of nutritional status and eating patterns in children with gastrointestinal diseases attending an outpatients clinic and contemporary healthy controls por Tsiountsioura, M, Wong, J, Upton, J, McIntyre, K, Dimakou, D, Buchanan, E, Cardigan, T, Flynn, D, Bishop, J, Russell, R, Barclay, A, McGrogan, P, Edwards, C, Gerasimidis, K

“…Background/objectives: In the era of modern multidisciplinary clinical management, very little is known about the prevalence and presentation of malnutrition in children with gastrointestinal disorders (GastroD) particularly employing composite, global measures of nutritional status. …”

Prevalence, risk factors and health outcomes associated with polypharmacy among urban community-dwelling older adults in multi-ethnic Malaysia por Lim, L.M., McStea, M., Chung, W.W., Azmi, N.N., Aziz, S.A.A., Alwi, S., Kamarulzaman, A., Kamaruzzaman, S.B., Chua, S.S., Rajasuriar, R.

“…The risk factors associated with increasing medication use were increasing age, Indian ethnicity, male, having a higher number of comorbidities specifically those diagnosed with cardiovascular, endocrine and gastrointestinal disorders, as well as supplement use. Health outcomes significantly associated with polypharmacy were PIMS, PDDIs and increased healthcare utilisation. …”

Fecal Nutrients Suggest Diets of Higher Fiber Levels in Free-Ranging than in Captive Proboscis Monkeys (Nasalis larvatus) por Ikki Matsuda, Henry Bernard, Augustine Tuuga, Sen K S S Nathan, John C M Sha, Ismon Osman, Rosa Sipangkui, Satoru Seino, Sanae Asano, Anna Wong, Michael Kreuzer, Ramirez Saldivar, Diana A, Marcus Clauss

“…This may contribute to gastrointestinal disorders often observed in zoos. An approach to obtain information relevant for the improvement of diets is to compare the nutrient composition of feces from free-ranging and captive individuals. …”
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Integrative analysis of heterogeneous genomic datasets to discover genetic etiology of autism spectrum disorders por Nazeen, Sumaiya

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Children with a history of prematurity presenting with snoring and sleep-disordered breathing por Manuel, A.M., Witmans, M., El-Hakim, H.

“…Comorbid pulmonary and gastrointestinal disorders were encountered on 23 (40%) and 17 (29.8%) occasions, respectively, and were the most commonly encountered comorbid diagnostic categories. …”

Observational histological study on the healing process of the ethanol-induced gastric ulcer treated with Xiang Sha Yang Wei Wan in comparison to ranitidine treated sprague dawley... por Al-Qaraghuli , Ahmed M.S., Nafie, Emad M., Al-Ani, Imad Matloub Dally, Faisal, Ghasak Ghazi

“…Introduction: Xiang Sha Yang Wei Wan (XSYWW) is a Chinese traditional medicine that is used for gastrointestinal disorders, specifically gastric ulcer in many countries of South-East Asia. …”
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Human translational studies investigating the neurocognitive effects of 5-HT4 receptor agonism por De Cates, AN

“…Although there was no evidence of an antidepressant-like effect in experimental medicine studies, a pharmaco-epidemiological study suggested that one year of standard dose prucalopride for the treatment of gastrointestinal disorders was associated with reduced risk of depression.…”

Non-Invasive Mapping of the Gastrointestinal Microbiota Identifies Children with Inflammatory Bowel Disease por Papa, Eli, Docktor, Michael, Smillie, Christopher, Weber, Sarah, Preheim, Sarah Pacocha, Gevers, Dirk, Giannoukos, Georgia, Ciulla, Dawn, Tabbaa, Diana, Ingram, Jay, Schauer, David B., Ward, Doyle V., Korzenik, Joshua R., Xavier, Ramnik J., Bousvaros, Athos, Alm, Eric J.

“…We investigated the use of 16S rRNA sequencing of fecal samples and new analytical methods to assess differences in the microbiota of children with IBD and other gastrointestinal disorders. Methodology/Principal Findings: We applied synthetic learning in microbial ecology (SLiME) analysis to 16S sequencing data obtained from i) published surveys of microbiota diversity in IBD and ii) fecal samples from 91 children and young adults who were treated in the gastroenterology program of Children’s Hospital (Boston, USA). …”
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Static and Dynamic Autonomic Response with Increasing Nausea Perception por LaCount, Lauren T., Barbieri, Riccardo, Park, Kyungmo, Kim, Jieun, Brown, Emery N., Kuo, Braden, Napadow, Vitaly

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