Survival benefit with checkpoint inhibitors versus chemotherapy is modified by brain metastases in patients with recurrent small cell lung cancer by Friederike C. Althoff, Lisa V. Schäfer, Fabian Acker, Lukas Aguinarte, Sophie Heinzen, Maximilian Rost, Akin Atmaca, Vivian Rosery, Jürgen Alt, Cornelius F. Waller, Niels Reinmuth, Gernot Rohde, Felix C. Saalfeld, Aaron Becker von Rose, Miriam Möller, Nikolaj Frost, Martin Sebastian, Jan A. Stratmann

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Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis by Mareike Lehmann, Lara Buhl, Hani N. Alsafadi, Stephan Klee, Sarah Hermann, Kathrin Mutze, Chiharu Ota, Michael Lindner, Jürgen Behr, Anne Hilgendorff, Darcy E. Wagner, Melanie Königshoff

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Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro model of lung fibrosis by Juliane Merl-Pham, Trayambak Basak, Larissa Knüppel, Deepak Ramanujam, Mark Athanason, Jürgen Behr, Stefan Engelhardt, Oliver Eickelberg, Stefanie M. Hauck, Roberto Vanacore, Claudia A. Staab-Weijnitz

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Characteristics of Current Smokers versus Former Smokers with COPD and Their Associations with Smoking Cessation Within 4.5 Years: Results from COSYCONET by Alter P, Stoleriu C, Kahnert K, Henke MO, Bals R, Trudzinski FC, Watz H, Speicher T, Söhler S, Welte T, Rabe KF, Wouters EFM, Vogelmeier CF, Jörres RA

“…Peter Alter,1 Cosmina Stoleriu,2 Kathrin Kahnert,3,4 Markus Oliver Henke,5 Robert Bals,6 Franziska C Trudzinski,7 Henrik Watz,8 Tim Speicher,1 Sandra Söhler,1 Tobias Welte,9 Klaus F Rabe,10,11 Emiel FM Wouters,12,13 Claus F Vogelmeier,1 Rudolf A Jörres14 1Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, Philipps University of Marburg (UMR), Member of the German Center for Lung Research (DZL), Marburg, Germany; 2Asklepios Lungenklinik Gauting, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Gauting, Germany; 3Department of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany; 4MediCenterGermering, Germering, Germany; 5Klinik für Innere Medizin und Pneumologie, Krankenhaus Martha-Maria, Munich, Germany; 6Department of Internal Medicine V, Pulmonology, Allergology, Intensive Care Medicine, Saarland University Hospital, Homburg, Germany; 7Department of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the Center for Lung Research (DZL), Heidelberg, Germany; 8Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany; 9Clinic for Pneumology, Hannover Medical School, Member of the German Center for Lung Research (DZL), Hannover, Germany; 10LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany; 11Department of Medicine, Christian-Albrechts-University, Kiel, Germany; 12Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, Netherlands; 13Ludwig Boltzmann Institute for Lung Health, Vienna, Austria; 14Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, GermanyCorrespondence: Peter Alter, Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, Philipps University of Marburg (UMR), Member of the German Center for Lung Research (DZL), Baldingerstrasse 1, Marburg, 35033, Germany, Tel +49 6421 5866140, Email Alter@uni-marburg.deBackground: Many patients with chronic obstructive pulmonary disease (COPD) continue smoking. …”
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Comparison of the sensitivity of different criteria to select lung cancer patients for screening in a cohort of German patients by Julia Walter, Diego Kauffmann‐Guerrero, Thomas Muley, Martin Reck, Jan Fuge, Andreas Günther, Raphael W. Majeed, Rajkumar Savai, Ina Koch, Julien Dinkel, Christian Schneider, Karsten Senghas, Sonja Kobinger, Farkhad Manapov, Michael Thomas, Kathrin Kahnert, Hauke Winter, Jürgen Behr, Martin Tammemägi, Amanda Tufman

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Clinical Translation and Validation of a Predictive Biomarker for Patritumab, an Anti-human Epidermal Growth Factor Receptor 3 (HER3) Monoclonal Antibody, in Patients With Advanced... by Jeanne Mendell, Daniel J. Freeman, Wenqin Feng, Thore Hettmann, Matthias Schneider, Sabine Blum, Jens Ruhe, Johannes Bange, Kenji Nakamaru, Shuquan Chen, Zenta Tsuchihashi, Joachim von Pawel, Catherine Copigneaux, Robert A. Beckman

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Prolonged weaning: From the intensive care unit to home by P. Navalesi, P. Frigerio, A. Patzlaff, S. HäuÃermann, P. Henseke, M. Kubitschek

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Differential Diagnosis and Proper Treatment of Acute Rhinosinusitis: Guidance Based on Historical Data Analysis by Gregor Cevc Ph.D., M.Sci.

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Two-Year Outcomes for the Double-Blind, Randomized, Sham-Controlled Study of Targeted Lung Denervation in Patients with Moderate to Severe COPD: AIRFLOW-2 by Valipour A, Shah PL, Herth FJ, Pison C, Schumann C, Hübner RH, Bonta PI, Kessler R, Gesierich W, Darwiche K, Lamprecht B, Perez T, Skowasch D, Deslee G, Marceau A, Sciurba FC, Gosens R, Hartman JE, Conway F, Duller M, Mayse M, Norman HS, Slebos DJ

“…Infektiologie und Pneumologie, Campus Virchow, Berlin, Germany; 7Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; 8Service de Pneumologie, Nouvel Hôpital Civil, Université de Strasbourg, Strasbourg, France; 9Asklepios-Fachkliniken Munich-Gauting, Comprehensive Pneumology Center Munich, Gauting, Germany; 10Department of Pulmonary Medicine, Section of Interventional Pneumology, Ruhrlandklinik - University Hospital Essen, University of Duisburg-Essen, Essen, Germany; 11Department of Pulmonary Medicine, Kepler Universitatsklinikum GmbH, Linz, Austria; 12CHU de Lille – Hôpital Calmette, Lille, France; 13Department of Internal Medicine II - Cardiology/Pneumology, University of Bonn, Bonn, Germany; 14CHU de Reims, Hôpital Maison Blanche, Service de Pneumologie, Reims, France; 15Service de Pneumologie, Hôpital Universitaire Bichat, Paris, France; 16University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 17Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; 18Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; 19Nuvaira, Inc., Minneapolis, MN, USACorrespondence: Dirk-Jan SlebosDepartment of Pulmonary Diseases/Interventional Bronchoscopy AA11, University Medical Center Groningen, PO Box 30001, Groningen, the NetherlandsTel +31 503612357Fax +31503619320Email d.j.slebos@umcg.nlPurpose: COPD exacerbations are associated with worsening clinical outcomes and increased healthcare costs, despite use of optimal medical therapy. …”
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P02.06 Integrated multi-omics unraveled a basal cell-dependent signature predictor of outcome and immunotherapy response in LUSC by Y Liu, X Guo, R Liu, J Jia, GT Stathopoulos, B Deng, L Trassl, GA Giotopoulou, SJ Behrend, AÖ Yildirim, AC Schamberger, IE Fernandez

Socio-economic, political, and institutional sustainability of agroforestry in Alta Verapaz, Guatemala by Sara Nicli, Jasmin Mantilla-Contreras, Roberto Waldemar Moya Fernandez, Markus Schermer, David Unger, Saskia Wolf, Stefan Zerbe

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Real-life data on Selexipag for the treatment of pulmonary hypertension by Michaela Barnikel, Nikolaus Kneidinger, Friederike Klenner, Andrea Waelde, Paola Arnold, Torben Sonneck, Jürgen Behr, Claus Neurohr, Katrin Milger

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Study design and rationale for the TETON phase 3, randomised, controlled clinical trials of inhaled treprostinil in the treatment of idiopathic pulmonary fibrosis by Vincent Cottin, Steven D Nathan, Lisa Lancaster, Peter Smith, Kevin R Flaherty, Jürgen Behr, CQ Deng, Natalie Pearce, Heidi Bell, Leigh Peterson

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Socio-demographic and psychiatric profile of patients hospitalized due to self-poisoning with suicidal intention by Maja Lumpe, Johannes Schurr, Christian Rabe, Armin Ott, Tobias Zellner, Michael Rentrop, Florian Eyer, Stefanie Geith

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Clinical evidence for respiratory insufficiency type II predicts weaning failure in long-term ventilated, tracheotomised patients: a retrospective analysis by Friederike Sophie Magnet, Hannah Bleichroth, Sophie Emilia Huttmann, Jens Callegari, Sarah Bettina Schwarz, Claudia Schmoor, Wolfram Windisch, Jan Hendrik Storre

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Anti-acid therapy in idiopathic pulmonary fibrosis: insights from the INPULSIS® trials by Ulrich Costabel, Jürgen Behr, Bruno Crestani, Wibke Stansen, Rozsa Schlenker-Herceg, Susanne Stowasser, Ganesh Raghu

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Review article: Heat shock protein 70 (Hsp70) peptide activated Natural Killer (NK) cells for the treatment of patients with non-small cell lung cancer (NSCLC) after radiochemother... by Hanno M Specht, Hanno M Specht, Norbert eAhrens, Christiane eBlankenstein, Thomas eDuell, Rainer eFietkau, Udo S Gaipl, Christine eGünther, Sophie eGunther, Gregor eHabl, Hubert eHautmann, Matthias eHautmann, Rudolf Maria Huber, Michael eMolls, Robert eOffner, Claus eRödel, Franz eRödel, Martin eSchuetz, Stephanie E Combs, Gabriele eMulthoff

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Nx4 Reduced Susceptibility to Distraction in an Attention Modulation Task by Kathrin Mayer, Marina Krylova, Marina Krylova, Sarah Alizadeh, Sarah Alizadeh, Hamidreza Jamalabadi, Hamidreza Jamalabadi, Johan van der Meer, Johannes C. Vester, Britta Naschold, Myron Schultz, Martin Walter, Martin Walter

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Infrared molecular fingerprinting of blood-based liquid biopsies for the detection of cancer by Marinus Huber, Kosmas V Kepesidis, Liudmila Voronina, Frank Fleischmann, Ernst Fill, Jacqueline Hermann, Ina Koch, Katrin Milger-Kneidinger, Thomas Kolben, Gerald B Schulz, Friedrich Jokisch, Jürgen Behr, Nadia Harbeck, Maximilian Reiser, Christian Stief, Ferenc Krausz, Mihaela Zigman

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Initial report on feasibility of PET/CT-based image-guided moderate hypofractionated thoracic irradiation in node-positive non-small cell lung Cancer patients with poor prognostic... by Chukwuka Eze, Julian Taugner, Olarn Roengvoraphoj, Nina-Sophie Schmidt-Hegemann, Lukas Käsmann, Cherylina Wijaya, Claus Belka, Farkhad Manapov

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