Real-world data of triplet combination of pyrotinib, trastuzumab, and chemotherapy in HER2-positive metastatic breast cancer: a multicenter, retrospective study by Shuhui You, Die Sang, Fei Xu, Ting Luo, Peng Yuan, Yizhao Xie, Biyun Wang

“…Notably, the most common grade 3/4 adverse events were diarrhea (37.8%), which were generally manageable. Conclusion: PyroHC shows promising efficacy and a satisfactory safety profile for treating HER2+ MBC, both as a first-line option and for heavily treated patients, including those with brain metastasis. …”
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Acne Among Japanese Patients with Atopic Dermatitis Receiving Upadacitinib in the Phase 3 Rising Up Study by Nobukazu Hayashi, Masanori Ikeda, John Liu, Eliza Raymundo, Yingyi Liu, Takuya Sasaki, Kenshi Yamasaki

“…Risk factors for acne included relevant concomitant medications (e.g., corticosteroids) started before acne onset and family and personal history of acne. Acne was generally managed with topical treatments. Conclusion Mild or moderate acne reported in Japanese patients with AD receiving upadacitinib occurred in a dose-dependent manner and had a variable onset time. …”
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THE POWER OF INTEGRATION TOWARDS SUSTAINABLE PERFORMANCE: A MODEL TO MINIMIZE TECHNOSTRESS AMONG FRONTLINE RESTAURANT EMPLOYEES BY COMBINING JOB AND EMPLOYEE RESOURCES by Mostafa A. HASSANIN, Amany E. SALEM, Mohamed Y. HELAL, Nabila N. ELSHAWARBI, Insaf S. AHMED, Neveen MANSOUR

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Feto-maternal Outcomes in Cesarean Section Compared to Vaginal Delivery in Eclamptic Patients in a Tertiary Level Hospital by Arifa Akter Jahan, Ferdousi Islam, Sheuly Begum

“…A rational therapy for general management of hypertension and convulsion has been established in Bangladesh by the Eclampsia Working Group. …”
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Unravelling the determinants of medical practice variation in referrals among primary care physicians: insights from a retrospective cohort study in Southern Israel by Moriah Ellen, Sagi Shashar, Victor Novack, Shlomi Codish, Ehud Davidson

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Decision-making methods in IT-outsourcing for enterprise information system by N.R. Poluektova, T.M. Knyshenko

“…However, the methods for assessing impact of such systems on the individual campaigns financial performance or on general management results, has not yet been determined. …”
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Modeling the interaction between salmon management and consumption by coastal brown bears by William W. Deacy, William B. Leacock, Jonathan B. Armstrong

“…Pacific salmon (Oncorhynchus spp.), a key food for many predators and an economically valuable harvested species, is generally managed for maximum sustained harvests without explicit consideration for the freshwater and terrestrial food webs that they support. …”
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Multiple load recognition and fatigue assessment on longitudinal stop of railway freight car by Zhou Wei, Wu Yitong, Liu Xiang, Gong Wei, Wang Hongjie, Li Guofei, Xiao Heting, Liu Dongrun, Kasimu Aliyu

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Exploring the sorting of patients in community health centres across Gauteng Province, South Africa by B. A. Stott, S. Moosa

“…There were three Factors Affecting Triage: Management Factor, including general management issues, equipment, documentation, infrastructure, protocol, and uniformity; and Staff Factor, including general staffing issues education and teamwork; and Patient Factor. …”
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Nebulized combined lignocaine and Salbutamol in treatment of acute asthma (A Pilot Study) by Yung, Chee Tien

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The effectiveness of groundwater recharges well to mitigate flood by Tunji, Lawal Abdul Qayoom, Abdul Latiff, Ab. Aziz, Tjahjanto, Dwi, Akib, Shatirah

Using the integration of human resource management strategies at district level to improve workforce performance: analysis of workplan designs in three African countries by Tim Martineau, Wesam Mansour, Marjolein Dieleman, Patricia Akweongo, Samuel Amon, Kingsley Chikaphupha, Paul Mubiri, Joanna Raven

“…Results About half (49%) of the DHMTs selected service-delivery problems while others selected workforce performance (46%) or general management (5%) problems, yet all workplans addressed health workforce-related causes through integrated workplans. …”
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Climate change literature across ecological disciplines: A review of the scope and level of specificity in management recommendations by Samantha M. Cady, David W. Londe, Samuel D. Fuhlendorf, Craig A. Davis, Abraham J. Kanz, Kiera L. Kauffman, Jennifer K. Knutson, Alexander G. Barnes, Nicholas A. McMillan, Landon K. Neumann

“…We also suggest that, for a general management principle to be well-positioned for being adapted into an action, it should: (1) be valid across multiple spatial and temporal scales or be clear about its limitations, (2) anticipate, or at least explicitly consider, alterations to systems and communities under future climate change scenarios and provide alternative management strategies accordingly, and (3) incorporate and describe major sources of uncertainty in the management strategies.…”
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Fecal microbiota and inflammatory and antioxidant status of obese and lean dogs, and the effect of caloric restriction by Carla Giuditta Vecchiato, Stefania Golinelli, Carlo Pinna, Rachel Pilla, Jan S. Suchodolski, Asta Tvarijonaviciute, Camila Peres Rubio, Elisa Dorato, Costanza Delsante, Claudio Stefanelli, Elena Pagani, Federico Fracassi, Giacomo Biagi

“…IntroductionObesity is the most common nutritional disease in dogs, and is generally managed by caloric restriction. Gut microbiota alteration could represent a predisposing factor for obesity development, which has been associated with a low-grade inflammatory condition and an impaired antioxidant status. …”
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Challenges in the profitability of small-scale broiler farming by avoiding injudicious use of drugs and additives by Shubash Chandra Das, Mosammad Zubiatin Tasmin, Afifa Afrin, Tanvir Ahmed, Ankon Lahiry, Shahina Rahman

“…First, a survey was undertaken in relation to farmers' basic information and general management methods in commercial broilers, with special attention given to the usage of medications and additives in drinking water. …”
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Roman Villa of Rabaçal, Penela, Portugal A Mediterranean Production Centre and Palatial Home with Mosaic Floors from the Late Antiquity in the Territory of the Ciuitas of Conimbrig... by Miguel PESSOA, Ana Luísa Ravara MENDES, Elsa SIMÕES, Sónia VICENTE

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Effect of a Food for Special Medical Purposes for Muscle Recovery, Consisting of Arginine, Glutamine and Beta-Hydroxy-Beta-Methylbutyrate on Body Composition and Skin Health in Ove... by Mariangela Rondanelli, Mara Nichetti, Gabriella Peroni, Maurizio Naso, Milena Anna Faliva, Giancarlo Iannello, Enrica Di Paolo, Simone Perna

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An analysis of the solar service provider industry in the Western Cape, South Africa by Roman Votteler, Johan Hough, Chanel Venter

“…All respondents were general managers or owners of a solar service provider, who were interviewed face to face. …”
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DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes by Daniele Spadaccini, Simone Perna, Gabriella Peroni, Giuseppe D’Antona, Giancarlo Iannello, Alessandro Faragli, Vittoria Infantino, Antonella Riva, Giovanna Petrangolini, Massimo Negro, Clara Gasparri, Mariangela Rondanelli

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A case report of anorexia nervosa in a 23‐year‐old Ethiopian woman by Selamawit Alemayehu Tessema, Surafel Worku Megersa, Meskerem Abebe, Hailegiorgis Getnet Ayalew, Melat Tigabu

“…The findings on psychiatric evaluation encompassing detailed history and mental state examination suggested the diagnosis of Extreme anorexia nervosa, restricting type; adult malnutrition; major depressive disorder (MDD) (in remission); low risk of aggression; low risk of suicide; severe functional impairment. The general management principles implemented in this patient included assessment of medical complications, weight restoration, psychological intervention, medication for comorbid depression, and long‐term psychological and biological treatment follow‐up to avoid relapse. …”
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