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Regulation of expression of the erythropoietin gene.
Published 1998“…In response to ischemic or hypoxic hypoxia, the level of expression of the gene increases markedly. We have a limited understanding of the factors governing the tissue specificity of erythropoietin gene expression but considerable progress has been made toward understanding the mechanisms that increase erythropoietin gene expression in response to hypoxia. …”
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Gene therapy for retinal disease.
Published 2013“…Gene therapy strategies for the treatment of inherited retinal diseases have made major advances in recent years. …”
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Monocyte gene expression data
Published 2023“…Poly-A RNA was paired-end sequenced in the Oxford Genome Centre using Illumina Hiseq-4000 machines. The data consists of gene level count data from mapped transcriptomes prepared with HT-seq.…”
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The ethics of germline gene editing
Published 2016“…Germline Gene Editing (GGE) has enormous potential both as a research tool and a therapeutic intervention. …”
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Dynamic nucleosomes and gene transcription.
Published 2006“…Gene transcription occurs on a nucleosomal template known as chromatin. …”
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Rapid gene cloning in wheat
Published 2019“…The identification of wheat and barley genes controlling important agronomic traits using positional cloning has traditionally been a challenging and time-consuming procedure. …”
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196
Association analysis of the vitamin D receptor gene, the type I collagen gene COL1A1, and the estrogen receptor gene in idiopathic osteoarthritis.
Published 2000“…OBJECTIVE: Evidence has accumulated supporting a role for genes in the etiology of osteoarthritis (OA). Several candidates have been targeted as potential susceptibility loci including genes that are involved in the regulation of bone density. …”
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Studying gene and gene-environment effects of uncommon and common variants on continuous traits: a marker-set approach using gene-trait similarity regression.
Published 2011“…These features make it an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium (LD) blocks, genes, or pathways in whole-genome analysis.…”
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Studying gene and gene-environment effects of uncommon and common variants on continuous traits: A marker-set approach using gene-trait similarity regression
Published 2011“…These features make it an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium (LD) blocks, genes, or pathways in whole-genome analysis. © 2011 The American Society of Human Genetics.…”
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When Noisy Neighbors Are a Blessing: Analysis of Gene Expression Noise Identifies Coregulated Genes
Published 2014“…In this issue of Molecular Cell, Stewart-Ornstein et al. (2012) use systematic pair-wise correlation analysis of expression noise in a large number of yeast genes to identify clusters of functionally related genes and signaling pathways responsible for elevated noise.…”
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