NetworKIN: a resource for exploring cellular phosphorylation networks by Jensen, Lars Juhl, Pasculescu, Adrian, Olhovsky, Marina, Colwill, Karen, Bork, Peer, Pawson, Tony, Linding, Rune, Yaffe, Michael B

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Experimental validation of in silico model-predicted isocitrate dehydrogenase and phosphomannose isomerase from Dehalococcoides mccartyi by Islam, M. Ahsanul, Tchigvintsev, Anatoli, Yim, Veronica, Savchenko, Alexei, Yakunin, Alexander F., Mahadevan, Radhakrishnan, Edwards, Elizabeth A.

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Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis by Mann, Paul A., Koseoglu, Sandra, Si, Qian, Kuzmin, Elena, Flattery, Amy, Harris, Guy, Sher, Xinwei, Murgolo, Nicholas, Wang, Hao, Devito, Kristine, de Pedro, Nuria, Genilloud, Olga, Kahn, Jennifer Nielsen, Jiang, Bo, Costanzo, Michael, Boone, Charlie, Garlisi, Charles G., Roemer, Terry, McLellan, Catherine, Lindquist, Susan

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Global metabolome analysis of Dunaliella tertiolecta, Phaeobacter italicus R11 co-cultures using thermal desorption - comprehensive two-dimensional gas chromatography - time-of-fli... by Armstrong, Michael D. Sorochan, Campos, O. René Arredondo, Bannon, Catherine C., de la Mata, A. Paulina, Case, Rebecca J., Harynuk, James J.

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Barnacle: detecting and characterizing tandem duplications and fusions in transcriptome assemblies by Swanson, Lucas, Robertson, Gordon, Mungall, Karen L., Butterfield, Yaron S., Chiu, Readman, Corbett, Richard D., Docking, T. R., Hogge, Donna, Jackman, Shaun D., Moore, Richard A., Mungall, Andrew J., Nip, Ka Ming, Parker, Jeremy D. K., Qian, Jenny Q., Raymond, Anthony, Sung, Sandy, Tam, Angela, Thiessen, Nina, Varhol, Richard, Wang, Sherry, Yorukoglu, Deniz, Zhao, YongJun, Hoodless, Pamela A., Sahinalp, S. C., Karsan, Aly, Birol, Inanc, Qian, Jenny, Sahinalp, S.

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Viral load kinetics and the clinical consequences of cytomegalovirus in kidney transplantation by Sabina Dobrer, Karen R. Sherwood, Ishan Hirji, James Lan, James Lan, John Gill, Nancy Matic, Paul A. Keown, Paul A. Keown

“…Here, we explore the importance of viral load kinetics as predictors of risk and potential guides to therapy to reduce transplant failure in a large longitudinal Genome Canada Transplant Consortium (GCTC) kidney transplant cohort.MethodsWe examined the relationship between CMV infection rates and clinical characteristics, CMV viral load kinetics, and graft and patient outcomes in 2510 sequential kidney transplant recipients in the British Columbia Transplant Program. …”
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Equity, diversity, and inclusion at the Global Alliance for Genomics and Health by Neerjah Skantharajah, Shakuntala Baichoo, Tiffany F. Boughtwood, Esmeralda Casas-Silva, Subhashini Chandrasekharan, Sanjay M. Dave, Khalid A. Fakhro, Aida B. Falcon de Vargas, Sylvia S. Gayle, Vivek K. Gupta, Rachele Hendricks-Sturrup, Ashley E. Hobb, Stephanie Li, Bastien Llamas, Catalina Lopez-Correa, Mavis Machirori, Jorge Melendez-Zajgla, Mareike A. Millner, Angela J.H. Page, Laura D. Paglione, Maili C. Raven-Adams, Lindsay Smith, Ericka M. Thomas, Judit Kumuthini, Manuel Corpas

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Updates in Kidney Transplantation From the 2022 Banff-Canadian Society of Transplantation Joint Meeting: Conference Report by Ian Carrigan, Sunita Mathur, Nicholas Bourgeois, Mélanie Dieudé, Daniel Fantus, Patricia Gongal, Anne Halpin, Alim Hirji, Holly Mansell, Caroline Piotrowski, Ruth Sapir-Pichhadze, Amanda J. Vinson

“…Molecular compatibility tools provide another means of improving SOTR outcomes, and the Genome Canada Transplant Consortium has been examining important considerations of their implementation. …”
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Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk by Wilcox, Naomi, Dumont, Martine, González-Neira, Anna, Carvalho, Sara, Beauparlant, Charles Joly, Crotti, Marco, Luccarini, Craig, Soucy, Penny, Dubois, Stéphane, Nuñez-Torres, Rocio, Pita, Guillermo, Gardner, Eugene J., Dennis, Joe, Alonso, M. Rosario, Álvarez, Nuria, Baynes, Caroline, Collin-Deschesnes, Annie Claude, Desjardins, Sylvie, Becher, Heiko, Behrens, Sabine, Bolla, Manjeet K., Castelao, Jose E., Chang-Claude, Jenny, Cornelissen, Sten, Dörk, Thilo, Engel, Christoph, Gago-Dominguez, Manuela, Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hartman, Mikael, Herráez, Belén, Jung, Audrey, Keeman, Renske, Kiechle, Marion, Li, Jingmei, Loizidou, Maria A., Lush, Michael, Michailidou, Kyriaki, Panayiotidis, Mihalis I., Sim, Xueling, Teo, Soo Hwang, Tyrer, Jonathan P., van der Kolk, Lizet E., Wahlström, Cecilia, Wang, Qin, Perry, John R. B., Benitez, Javier, Schmidt, Marjanka K., Schmutzler, Rita K., Pharoah, Paul D. P., Droit, Arnaud, Dunning, Alison M., Kvist, Anders, Devilee, Peter, Easton, Douglas F., Simard, Jacques, Tan, Benita Kiat-Tee, Tan,Veronique Kiak Mien, Tan, Su-Ming, Lim, Geok Hoon, Tan, Ern Yu, Ho, Peh Joo, Khng, Alexis Jiaying

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Impact on costs and outcomes of multi-gene panel testing for advanced solid malignancies: a cost-consequence analysis using linked administrative dataResearch in context by Alberto Hernando-Calvo, Paul Nguyen, Philippe L. Bedard, Kelvin K.W. Chan, Ramy R. Saleh, Deirdre Weymann, Celeste Yu, Eitan Amir, Dean A. Regier, Bishal Gyawali, Danielle Kain, Brooke Wilson, Craig C. Earle, Nicole Mittmann, Albiruni R. Abdul Razak, Wanrudee Isaranuwatchai, Peter Sabatini, Anna Spreafico, Tracy L. Stockley, Trevor J. Pugh, Christine Williams, Lillian L. Siu, Timothy P. Hanna

“…Funding: T.P H holds a research grant provided by the Ontario Institute for Cancer Research through funding provided by the Government of Ontario (#IA-035 and P.HSR.158) and through funding of the Canadian Network for Learning Healthcare Systems and Cost-Effective ‘Omics Innovation (CLEO) via Genome Canada (G05CHS).…”
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GAA-FGF14 disease: defining its frequency, molecular basis, and 4-aminopyridine response in a large downbeat nystagmus cohortResearch in context by David Pellerin, Felix Heindl, Carlo Wilke, Matt C. Danzi, Andreas Traschütz, Catherine Ashton, Marie-Josée Dicaire, Alexanne Cuillerier, Giulia Del Gobbo, Kym M. Boycott, Jens Claassen, Dan Rujescu, Annette M. Hartmann, Stephan Zuchner, Bernard Brais, Michael Strupp, Matthis Synofzik

“…The Care4Rare Canada Consortium is funded in part by Genome Canada and the Ontario Genomics Institute (OGI-147 to KMB), the Canadian Institutes of Health Research (CIHR GP1-155867 to KMB), Ontario Research Foundation, Genome Quebec, and the Children's Hospital of Eastern Ontario Foundation. …”
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