Is the Institute Georges Lopez-1 solution an equally effective, cheaper alternative to the University of Wisconsin solution in liver transplantation? by Magnus Mansard, Ravichand Siddachari, Sanjay Govil, Suresh Doraiswamy, Goutham Kumar, Navaneethan Subramanian, Olithselvan Arikichenin

“…Aim: To compare the outcomes of deceased donor liver transplantation (DDLT) using either the University of Wisconsin solution (UW) or the Institute Georges Lopez-1 (IGL-1) solution. Materials and Methods: Adult patients who underwent DDLT between November 2015 and March 2018 were included in the study. …”
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Characterizing Autophagy in the Cold Ischemic Injury of Small Bowel Grafts: Evidence from Rat Jejunum by Ibitamuno Caleb, Luca Erlitz, Vivien Telek, Mónika Vecsernyés, György Sétáló, Péter Hardi, Ildikó Takács, Gábor Jancsó, Tibor Nagy

“…Cold preservation was simulated by placing the small intestines of Wistar rats in an IGL-1 (Institute George Lopez) solution at 4 °C for varying periods (3, 6, 9, and 12 h). …”
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Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury by Arnau Panisello-Roselló, Norma Alva, Marta Flores, Alexandre Lopez, Carlos Castro Benítez, Emma Folch-Puy, Anabela Rolo, Carlos Palmeira, René Adam, Teresa Carbonell, Joan Roselló-Catafau

“…Institut George Lopez-1 (IGL-1) and Histidine-tryptophan-ketoglutarate (HTK) solutions are proposed as alternatives to UW (gold standard) in liver preservation. …”
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Static cold storage preservation of ischemically damaged kidneys. a comparison between IGL-1 and UW solution. by Maathuis, M, Ottens, P, van Goor, H, Zwaagstra, J, Wiersema-Buist, J, Schuurs, T, Ploeg, R, Leuvenink, H

“…Especially in damaged organs, adequate organ preservation is critically important to maintain viability. Institut Georges Lopez-1 (IGL-1) is a new preservation solution, with an extracellular sodium/potassium ratio and polyethylene glycol as a colloid. …”

Impact of an intra-abdominal cooling device during open kidney transplantation in pigs by Alban Longchamp, Raphael P.H. Meier, Nicola Colucci, Alexandre Balaphas, Lorenzo A. Orci, Antonio Nastasi, Grégoire Longchamp, Solange Moll, Antoine Klauser, Manuel Pascual, François Lazeyras, Jean-Marc Corpataux, Leo Bühler

“…Following procurement, kidneys were flushed with 4°C Institut Georges Lopez-1 preservation solution, and placed on ice. …”
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IGL-1 preservation solution in kidney and pancreas transplantation: A systematic review. by Melanie Habran, Julie De Beule, Ina Jochmans

“…We aimed to systematically review published data on the effectiveness of Institut Georges Lopez-1 (IGL-1) as a preservation solution for kidney and pancreas grafts. …”
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Utility of Islet Cell Preparations From Donor Pancreases After Euthanasia by Diedert L. De Paep, Freya Van Hulle, Zhidong Ling, Marian Vanhoeij, Robert Hilbrands, Wim Distelmans, Pieter Gillard, Bart Keymeulen, Daniel Pipeleers, Daniel Jacobs-Tulleneers-Thevissen

“…A procedure for DCD V procurement provided 13 pancreases preserved in Institut Georges Lopez-1 preservation solution and following acirculatory warm ischemia time under 10 minutes. …”
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Deterioration of endothelial and smooth muscle cell function in DCD kidneys after static cold storage in IGL-1 or UW. by Maathuis, M, de Groot, M, Ploeg, R, Leuvenink, H

“…We compared kidney preservation using the new extracellular-type cold storage solution from Institut Georges Lopez (IGL-1) with the University of Wisconsin solution (UW) and focused on vasomotor functions. …”

Lower beta cell yield from donor pancreases after controlled circulatory death prevented by shortening acirculatory warm ischemia time and by using IGL-1 cold preservation solution... by Diedert L De Paep, Freya Van Hulle, Zhidong Ling, Marian Vanhoeij, Jacques Pirenne, Bart Keymeulen, Daniel Pipeleers, Daniel Jacobs-Tulleneers-Thevissen

“…Beta cell number correlated negatively with duration of acirculatory warm ischemia time above 10 min; for shorter acirculatory warm ischemia time, DCD III-organs did not exhibit a lower beta cell yield (74 x 106 beta cells). Use of Institut Georges Lopez-1 cold preservation solution instead of University of Wisconsin solution or histidine-tryptophan-ketoglutarate also protected against the loss in beta cell yield from DCD III-organs (86 x 106 for IGL-1 versus 54 x 106 and 65 x 106 beta cells respectively, p = 0.042). …”
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Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. by Mohamed Bejaoui, Eirini Pantazi, Viviana De Luca, Arnau Panisello, Emma Folch-Puy, Georgina Hotter, Clemente Capasso, Claudiu T Supuran, Joan Roselló-Catafau

“…Two different aspects of the role of CA II in fatty liver grafts preservation were evaluated: 1) the effect of its addition to Institut Georges Lopez (IGL-1) storage solution after cold ischemia; 2) and after 24h of cold storage followed by two hours of normothermic ex-vivo perfusion. …”
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Clinical Outcomes of Transplanted Kidneys from Deceased Donors Using Different Generic Preservation Solutions by Aureliusz Kolonko, Natalia Słabiak-Błaż, Robert Król, Andrzej Więcek

“…<i>Background and Objectives</i>: StoreProtect Plus^® is a preserving solution for cold organ storage, with a composition identical to Institute Georges Lopez (IGL-1) solution. The aim of this single center study was to compare the clinical performance of StoreProtect Plus with the generic counterpart of University of Wisconsin preservation fluid, named SPS-1^®. …”
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