428 Interim analysis of Phase 2 results for cemiplimab in patients with metastatic basal cell carcinoma (mBCC) who progressed on or are intolerant to hedgehog inhibitors (HHIs) by Marcus Butler, Rogerio Neves, Lisa Licitra, Israel Lowy, Zeynep Eroglu, Karl Lewis, Leonel Hernandez-Aya, Axel Hauschild, Emmanuel Okoye, Siyu Li, Jean-Francois Baurain, Oliver Bechter, Ketty Peris, Aleksandar Sekulic, Alexander Stratigos, Lara Dunn, Anne Lynn Chang, Michael Migden, Kosalai Mohan, Ebony Coates, Emily Ruiz, Frank Seebach, David Weinreich, George Yancopoulos, Timothy Bowler, Matthew Fury

Urine Single-Cell RNA Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures by Khun Zaw Latt, Jurgen Heymann, Joseph H. Jessee, Avi Z. Rosenberg, Celine C. Berthier, Arnon Arazi, Sean Eddy, Teruhiko Yoshida, Yongmei Zhao, Vicky Chen, George W. Nelson, Margaret Cam, Parimal Kumar, Monika Mehta, Michael C. Kelly, Matthias Kretzler, Patricio E. Ray, Marva Moxey-Mims, Gregory H. Gorman, Brent L. Lechner, Renu Regunathan-Shenk, Dominic S. Raj, Katalin Susztak, Cheryl A. Winkler, Jeffrey B. Kopp

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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry by Ben C. Collins, Christie L. Hunter, Yansheng Liu, Birgit Schilling, George Rosenberger, Samuel L. Bader, Daniel W. Chan, Bradford W. Gibson, Anne-Claude Gingras, Jason M. Held, Mio Hirayama-Kurogi, Guixue Hou, Christoph Krisp, Brett Larsen, Liang Lin, Siqi Liu, Mark P. Molloy, Robert L. Moritz, Sumio Ohtsuki, Ralph Schlapbach, Nathalie Selevsek, Stefani N. Thomas, Shin-Cheng Tzeng, Hui Zhang, Ruedi Aebersold

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Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma by Alexandra Gyurdieva, Stefan Zajic, Ya-Fang Chang, E. Andres Houseman, Shan Zhong, Jaegil Kim, Michael Nathenson, Thomas Faitg, Mary Woessner, David C. Turner, Aisha N. Hasan, John Glod, Rosandra N. Kaplan, Sandra P. D’Angelo, Dejka M. Araujo, Warren A. Chow, Mihaela Druta, George D. Demetri, Brian A. Van Tine, Stephan A. Grupp, Gregg D. Fine, Ioanna Eleftheriadou

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A developmental approach to diversifying neuroscience through effective mentorship practices: perspectives on cross-identity mentorship and a critical call to action by Tanisha G. Hill-Jarrett, Rowena Ng, Rowena Ng, Carlos Cardenas-Iniguez, Jemima Akinsanya, Ismary Blanco, Johnathan M. Borland, James S. Brown, Tameka Clemons, Adriana K. Cushnie, Jacqueline Garcia, Brianna George, Cera W. Hassinan, Cera W. Hassinan, Timothy J. Hines, Dan Landayan, Taylor A. McCorkle, Katherine R. Meckel, Katherine R. Meckel, Mariajose Metcalfe, Samantha A. Montoya, Deborah K. Rose, Desmond R. Warren

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A Multi-Institutional Experience of Proton Beam Therapy for Sinonasal Tumors by Nathan Y. Yu, MD, Mauricio E. Gamez, MD, William F. Hartsell, MD, Henry K. Tsai, MD, George E. Laramore, MD, PhD, Gary L. Larson, MD, Charles B. Simone, II, MD, Carl Rossi, MD, Sanford R. Katz, MD, Matthew R. Buras, MS, Michael A. Golafshar, MS, Carlos E. Vargas, MD, Samir H. Patel, MD

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The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized... by Philip C. Spinella, Kimberly A. Thomas, Isaiah R. Turnbull, Anja Fuchs, Kelly Bochicchio, Douglas Schuerer, Stacey Reese, Adrian A. Coleoglou Centeno, Christopher B. Horn, Jack Baty, Susan M. Shea, M. Adam Meledeo, Anthony E. Pusateri, Jerrold H. Levy, Andrew P. Cap, Grant V. Bochicchio, for the TAMPITI Investigators, M.D. Enyo Ablordeppey, M.P.H. James Fehr, M.D. Philip Miller, M.D. George Despotis, M.D. Melanie Fields, M.D. Kevin Ward

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Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA by Xiaowei Hu, Jeongok G. Logan, Younghoon Kwon, Joao A. C. Lima, David R. Jacobs, Daniel Duprez, Lyndia Brumback, Kent D. Taylor, Peter Durda, W. Craig Johnson, Elaine Cornell, Xiuqing Guo, Yongmei Liu, Russell P. Tracy, Thomas W. Blackwell, George Papanicolaou, Gary F. Mitchell, Stephen S. Rich, Jerome I. Rotter, David J. Van Den Berg, Julio A. Chirinos, Timothy M. Hughes, Francine E. Garrett-Bakelman, Ani Manichaikul

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Predictors of outcomes after surgery for medically intractable insular epilepsy: A systematic review and individual participant data meta‐analysis by Sami Obaid, Jia‐Shu Chen, George M. Ibrahim, Alain Bouthillier, Evan Dimentberg, Werner Surbeck, Elena Guadagno, Tristan Brunette‐Clément, Nathan A. Shlobin, Aidan Shulkin, Andrew T. Hale, Luke D. Tomycz, Marec Von Lehe, Michael Scott Perry, Francine Chassoux, Viviane Bouilleret, Delphine Taussig, Martine Fohlen, Georg Dorfmuller, Koichi Hagiwara, Jean Isnard, Chima O. Oluigbo, Naoki Ikegaya, Dang K. Nguyen, Aria Fallah, Alexander G. Weil

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Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery by Massimo Sartelli, Marja A. Boermeester, Miguel Cainzos, Federico Coccolini, Stijn W. de Jonge, Kemal Rasa, E. Patchen Dellinger, Deborah A. McNamara, Donald E. Fry, Yunfeng Cui, Samir Delibegovic, Zaza Demetrashvili, Belinda De Simone, George Gkiokas, Timothy C. Hardcastle, Kamal M. F. Itani, Arda Isik, Francesco Maria Labricciosa, Varut Lohsiriwat, Sanjay Marwah, Tadeja Pintar, Jennifer Rickard, Vishal G. Shelat, Fausto Catena, Philip S. Barie

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Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10+ advanced non-small cell lung cancer by Victor Moreno, Andrew Gerry, Tom Holdich, Anthony J Olszanski, Ramaswamy Govindan, John V Heymach, Matthew J Frigault, Siddhartha Devarakonda, Melissa Johnson, Justin Gainor, Carlos Bachier, Natalie Hyland, Jean-Marc Navenot, Svetlana Fayngerts, Jane Bai, Elliot Norry, Robyn Broad, George R Blumenschein, Martin J Edelman, Bernard Doger de Spéville, Vincent K Lam, Zohar Wolchinsky, Dzmitry Batrakou, Melissa M Pentony, Joseph P Sanderson, Diane Marks, Paula M Fracasso

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Preclinical Ultra-High Dose Rate (FLASH) Proton Radiation Therapy System for Small Animal Studies by Ning Cao, PhD, Danielle P. Johnson Erickson, PhD, Eric C. Ford, PhD, Robert C. Emery, MS, Marissa Kranz, MS, Peter Goff, MD, PhD, Marco Schwarz, PhD, Juergen Meyer, PhD, Tony Wong, PhD, Jatinder Saini, PhD, MBA, Charles Bloch, PhD, Robert D. Stewart, PhD, George A. Sandison, PhD, Alec Morimoto, BS, Ava DeLonais-Dick, BS, Ben A. Shaver, BS, Ramesh Rengan, MD, PhD, Jing Zeng, MD

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National Psoriasis Foundation Telemedicine Task Force guidance for management of psoriatic disease via telemedicineCapsule Summary by Natalia Pelet del Toro, MD, Rayan Yahia, BS, Steven R. Feldman, MD, PhD, Abby Van Voorhees, MD, Lawrence Green, MD, Sergio Schwartzman, MD, Evan Siegel, MD, Kelly M. Cordoro, MD, Seemal R. Desai, MD, Leon Kircik, MD, Wilson Liao, MD, Jason E. Hawkes, MD, MS, Jeffrey Weinberg, MD, John Koo, MD, Elizabeth Brezinski Wallace, MD, Leah M. Howard, JD, April Armstrong, MD, George Han, MD, PhD

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Core‐binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I‐CBFit) by Celalettin Ustun, Elizabeth Morgan, Erica E. M. Moodie, Sheeja Pullarkat, Cecilia Yeung, Sigurd Broesby‐Olsen, Robert Ohgami, Young Kim, Wolfgang Sperr, Hanne Vestergaard, Dong Chen, Philip M. Kluin, Michelle Dolan, Krzysztof Mrózek, David Czuchlewski, Hans‐Peter Horny, Tracy I. George, Thomas Kielsgaard Kristensen, Nam K. Ku, Cecilia Arana Yi, Michael Boe Møller, Guido Marcucci, Linda Baughn, Ana‐Iris Schiefer, J. R. Hilberink, Vinod Pullarkat, Ryan Shanley, Jessica Kohlschmidt, Janie Coulombe, Amandeep Salhotra, Lori Soma, Christina Cho, Michael A. Linden, Cem Akin, Jason Gotlib, Gregor Hoermann, Jason Hornick, Ryo Nakamura, Joachim Deeg, Clara D. Bloomfield, Daniel Weisdorf, Mark R. Litzow, Peter Valent, Gerwin Huls, Miguel‐Angel Perales, Gautam Borthakur

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Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen‐specific T cell responses in allergic sensitized children by Ricardo daSilva Antunes, Aaron Sutherland, April Frazier, Veronique Schulten, Anna Pomés, Jill Glesner, Agustin Calatroni, Matthew C. Altman, Robert A. Wood, George T. O'Connor, Jacqueline A. Pongracic, Gurjit K. Khurana Hershey, Carolyn M. Kercsmar, Rebecca S. Gruchalla, Michelle Gill, Andrew H. Liu, Edward Zoratti, Meyer Kattan, Paula J. Busse, Leonard B. Bacharier, Stephen J. Teach, Lisa M. Wheatley, Alkis Togias, William W. Busse, Daniel J. Jackson, Alessandro Sette

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Targeting neurons in the gastrointestinal tract to treat Parkinson's disease by Robert A. Hauser, Dean Sutherland, Juan A. Madrid, Maria Angeles Rol, Steven Frucht, Stuart Isaacson, Fernando Pagan, Brian N. Maddux, George Li, Winona Tse, Benjamin L. Walter, Rajeev Kumar, Daniel Kremens, Mark F. Lew, Aaron Ellenbogen, Odinachi Oguh, Alberto Vasquez, William Kinney, Matt Lowery, Maria Resnick, Nicole Huff, Jerry Posner, Karla V. Ballman, Brian E. Harvey, Michael Camilleri, Michael Zasloff, Denise Barbut

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Cost-effectiveness of dual maternal HIV and syphilis testing strategies in high and low HIV prevalence countries: a modelling study by Patricia J Rodriguez, MPH, D Allen Roberts, MPH, Julianne Meisner, BVM&S, Monisha Sharma, PhD, Morkor Newman Owiredu, MBChB, Bertha Gomez, MD, Maeve B Mello, PhD, Alexey Bobrik, MD, Arkadii Vodianyk, MD, Andrew Storey, MBA, George Githuka, MBChB, Thato Chidarikire, PhD, Ruanne Barnabas, DPhil, Magdalena Barr-Dichiara, MPH, Muhammad S Jamil, PhD, Rachel Baggaley, MBBS, Cheryl Johnson, MA, Melanie M Taylor, MD, Alison L Drake, PhD

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Weight-based enoxaparin thromboprophylaxis in young trauma patients: analysis of the CLOTT-1 registry by Sarah Lombardo, Ram Nirula, Elliott R Haut, Scott Brakenridge, Brandon Bruns, Charles E Wade, M Margaret Knudson, Thomas Scalea, Todd W Costantini, Lisa Marie Knowlton, David Spain, Ernest E Moore, Michelle K McNutt, Matthew J Martin, Andrew J Kerwin, George C Velmahos, Bruce Crookes, Marta McCrum, Lucy Kornblith, Mark D Cipolle, Laszlo N Kiraly, David J Milia, Alicia Mohr, Frederick Rogers, Sherry Sixta, Jade Nunez

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Global access to surgical care: a modelling study by Blake C Alkire, MD, Dr. Nakul P Raykar, MD, Mark G Shrime, MD, Thomas G Weiser, MD, Prof. Stephen W Bickler, MD, John A Rose, MD, Cameron T Nutt, BA, Sarah L M Greenberg, MD, Meera Kotagal, MD, Johanna N Riesel, MD, Micaela Esquivel, MD, Tarsicio Uribe-Leitz, MD, George Molina, MD, Prof. Nobhojit Roy, MD, John G Meara, MD, Prof. Paul E Farmer, MD

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Diagnostic and molecular testing patterns in patients with newly diagnosed acute myeloid leukemia in the Connect® MDS/AML Disease Registry by Daniel A. Pollyea, Tracy I. George, Mehrdad Abedi, Rafael Bejar, Christopher R. Cogle, Kathryn Foucar, Guillermo Garcia‐Manero, David L. Grinblatt, Rami S. Komrokji, Jaroslaw P. Maciejewski, Dennis A. Revicki, Gail J. Roboz, Michael R. Savona, Bart L. Scott, Mikkael A. Sekeres, Michael A. Thompson, Sandra E. Kurtin, Chrystal U. Louis, Melissa Nifenecker, E. Dawn Flick, Arlene S. Swern, Pavel Kiselev, David P. Steensma, Harry P. Erba

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