Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data by Dmitry Shungin, Simon Haworth, Kimon Divaris, Cary S. Agler, Yoichiro Kamatani, Myoung Keun Lee, Kelsey Grinde, George Hindy, Viivi Alaraudanjoki, Paula Pesonen, Alexander Teumer, Birte Holtfreter, Saori Sakaue, Jun Hirata, Yau-Hua Yu, Paul M. Ridker, Franco Giulianini, Daniel I. Chasman, Patrik K. E. Magnusson, Takeaki Sudo, Yukinori Okada, Uwe Völker, Thomas Kocher, Vuokko Anttonen, Marja-Liisa Laitala, Marju Orho-Melander, Tamar Sofer, John R. Shaffer, Alexandre Vieira, Mary L. Marazita, Michiaki Kubo, Yasushi Furuichi, Kari E. North, Steve Offenbacher, Erik Ingelsson, Paul W. Franks, Nicholas J. Timpson, Ingegerd Johansson

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Disclosing quantitative RT‐PCR raw data during manuscript submission: a call for action by Andreas Untergasser, Jan Hellemans, Michael W. Pfaffl, Jan M. Ruijter, Maurice J. B. van denHoff, Mihnea P. Dragomir, Douglas Adamoski, Sandra Martha Gomes Dias, Rui Manuel Reis, Manuela Ferracin, Emmanuel Dias‐Neto, Ian Marsh, Mikael Kubista, Muller Fabbri, Ajay Goel, Ondřej Slabý, Erik Knutsen, Baoqing Chen, Massimo Negrini, Koshi Mimori, Martin Pichler, Maria Papatriantafyllou, Simone Anfossi, Thomas D. Schmittgen, Jim Huggett, Stephen Bustin, Jo Vandesompele, George A. Calin, for the HEROIC (tHe initiativE gRoup On qRT dIsClosure) Consortium

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S248: SIERRA TRIAL RESULTS WITH A TARGETED RADIOTHERAPY, IOMAB-B, A MYELOABLATIVE CONDITIONING WITH REDUCED INTENSITY TOLERABILITY YIELDS HIGH CR, LONG TERM SURVIVAL IN HSCT INELIG... by Boglarka Gyurkocza, Stuart Seropian, Hannah Choe, Mark Litzow, Camille Abboud, Nebu Koshy, Patrick Stiff, Benjamin Tomlinson, Sunil Abhyankar, James M Foran, Parameswaran Hari, George Chen, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie Orozco, Katarzyna Jamieson, Margarida Silverman, Koen Van Besien, Michael Schuster, Arjun Law, Sameem Abedin, Karilyn Larkin, Scott Rowley, Pashna Munshi, Rachel Cook, Sebastian Mayer, Moshe Yair Levy, Hillard Lazarus, Brenda Sandmaier, Vijay Reddy, Jennifer Spross, Kathleen Mcnamara, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, John Pagel, Sergio Giralt, Avinash Desai, Rajneesh Nath

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P1017: REDUCTIONS IN INDOLENT SYSTEMIC MASTOCYTOSIS BIOMARKER BURDEN WITH AVAPRITINIB IN THE REGISTRATIONAL, DOUBLE-BLIND PLACEBO-CONTROLLED PIONEER TRIAL by Jason Gotlib, Mariana Castells, Hanneke Oude Elberink, Frank Siebenhaar, Karin Hartmann, Sigurd Broesby-Olsen, Tracy I. George, Jens Panse, Ivan Alvarez-Twose, Deepti Radia, Tsewang Tashi, Cristina Bulai Livideanu, Vito Sabato, Paul Van Daele, Sonia Cerquozzi, Ingunn Dybedal, Andreas Reiter, Celalettin Ustun, Philippe Schafhausen, Prithviraj Bose, Daniel J. Deangelo, Lindsay Rein, Pankit Vachhani, Massimo Triggiani, Mark Rafferty, Nauman Butt, Stephen Oh, Friederike Wortmann, Johanna Ungerstedt, Minakshi Taparia, Andrew T. Kuykendall, Cecilia Arana Yi, Mattias Mattsson, William Shomali, Matthew Giannetti, Ilda Bidollari, Hui-Min Lin, Robyn Scherber, Maria Roche, Cem Akin, Marcus Maurer

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Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations by Robert R. Edwards, Robert H. Dworkin, Dennis C. Turk, Martin S. Angst, Raymond Dionne, Roy Freeman, Per Hansson, Simon Haroutounian, Lars Arendt-Nielsen, Nadine Attal, Ralf Baron, Joanna Brell, Shay Bujanover, Laurie B. Burke, Daniel Carr, Amy S. Chappell, Penney Cowan, Mila Etropolski, Roger B. Fillingim, Jennifer S. Gewandter, Nathaniel P. Katz, Ernest A. Kopecky, John D. Markman, George Nomikos, Linda Porter, Bob A. Rappaport, Andrew S.C. Rice, Joseph M. Scavone, Joachim Scholz, Lee S. Simon, Shannon M. Smith, Jeffrey Tobias, Tina Tockarshewsky, Christine Veasley, Mark Versavel, Ajay D. Wasan, Warren Wen, David Yarnitsky

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Reinfection with SARS-CoV-2 and Waning Humoral Immunity: A Case Report by Jason D. Goldman, Kai Wang, Katharina Röltgen, Sandra C. A. Nielsen, Jared C. Roach, Samia N. Naccache, Fan Yang, Oliver F. Wirz, Kathryn E. Yost, Ji-Yeun Lee, Kelly Chun, Terri Wrin, Christos J. Petropoulos, Inyoul Lee, Shannon Fallen, Paula M. Manner, Julie A. Wallick, Heather A. Algren, Kim M. Murray, Jennifer Hadlock, Daniel Chen, Chengzhen L. Dai, Dan Yuan, Yapeng Su, Joshua Jeharajah, William R. Berrington, George P. Pappas, Sonam T. Nyatsatsang, Alexander L. Greninger, Ansuman T. Satpathy, John S. Pauk, Scott D. Boyd, James R. Heath

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Full-thickness resection device (FTRD) for treatment of upper gastrointestinal tract lesions: the first international experience by Kaveh Hajifathalian, Yervant Ichkhanian, Qais Dawod, Alexander Meining, Arthur Schmidt, Nicholas Glaser, Kia Vosoughi, David L. Diehl, Ian S. Grimm, Theodore James, Adam W. Templeton, Jason B. Samarasena, Nabil El Hage Chehade, John G. Lee, Kenneth J. Chang, Meir Mizrahi, Mohammed Barawi, Shayan Irani, Shai Friedland, Paul Korc, Abdul Aziz Aadam, Mohammad Al-Haddad, Thomas E. Kowalski, George Smallfield, Gregory G. Ginsberg, Norio Fukami, Michael Lajin, Nikhil A. Kumta, Shou-jiang Tang, Yehia Naga, Stuart K. Amateau, Franklin Kasmin, Martin Goetz, Stefan Seewald, Vivek Kumbhari, Saowanee Ngamruengphong, Srihari Mahdev, Saurabh Mukewar, Kartik Sampath, David L. Carr-Locke, Mouen A. Khashab, Reem Z. Sharaiha

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Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity by Thomas C. Westbrook, Xiangnan Guan, Eva Rodansky, Diana Flores, Chia Jen Liu, Aaron M. Udager, Radhika A. Patel, Michael C. Haffner, Ya-Mei Hu, Duanchen Sun, Tomasz M. Beer, Adam Foye, Rahul Aggarwal, David A. Quigley, Jack F. Youngren, Charles J. Ryan, Martin Gleave, Yuzhuo Wang, Jiaoti Huang, Ilsa Coleman, Colm Morrissey, Peter S. Nelson, Christopher P. Evans, Primo Lara, Robert E. Reiter, Owen Witte, Matthew Rettig, Christopher K. Wong, Alana S. Weinstein, Vlado Uzunangelov, Josh M. Stuart, George V. Thomas, Felix Y. Feng, Eric J. Small, Joel A. Yates, Zheng Xia, Joshi J. Alumkal

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Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults by Srabanti Rakshit, Srabanti Rakshit, Vasista Adiga, Vasista Adiga, Vasista Adiga, Asma Ahmed, Asma Ahmed, Chaitra Parthiban, Chaitra Parthiban, Nirutha Chetan Kumar, Nirutha Chetan Kumar, Pratibha Dwarkanath, Sudarshan Shivalingaiah, Srishti Rao, George D’Souza, Mary Dias, Thomas J. A. Maguire, Katie J. Doores, Martijn Zoodsma, Martijn Zoodsma, Busranur Geckin, Prokar Dasgupta, Sudhir Babji, Krista E. van Meijgaarden, Simone A. Joosten, Tom H. M. Ottenhoff, Yang Li, Yang Li, Mihai G. Netea, Kenneth D. Stuart, Stephen C. De Rosa, M. Juliana McElrath, M. Juliana McElrath, Annapurna Vyakarnam, Annapurna Vyakarnam, Annapurna Vyakarnam

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Safety and efficacy of digital single-operator pancreatoscopy for obstructing pancreatic ductal stones by Olaya I. Brewer Gutierrez, Isaac Raijman, Raj J. Shah, B. Joseph Elmunzer, George J.M. Webster, Douglas Pleskow, Stuart Sherman, Richard P. Sturgess, Divyesh V. Sejpal, Christopher Ko, Attilio Maurano, Douglas G. Adler, Daniel K. Mullady, Daniel S. Strand, Christopher J. DiMaio, Cyrus Piraka, Reem Sharahia, Mohamad H. Dbouk, Samuel Han, Clayton M. Spiceland, Noor L.H. Bekkali, Moamen Gabr, Benjamin Bick, Laura K. Dwyer, Dennis Han, James Buxbaum, Claudio Zulli, Natalie Cosgrove, Andrew Y. Wang, David Carr-Locke, Tossapol Kerdsirichairat, Hanaa Dakour Aridi, Robert Moran, Shawn Shah, Juliana Yang, Omid Sanaei, Nasim Parsa, Vivek Kumbhari, Vikesh K. Singh, Mouen A. Khashab

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Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction by George J. Xu, Matthew A. Loberg, Jean-Nicolas Gallant, Quanhu Sheng, Sheau-Chiann Chen, Brian D. Lehmann, Sophia M. Shaddy, Megan L. Tigue, Courtney J. Phifer, Li Wang, Mario W. Saab-Chalhoub, Lauren M. Dehan, Qiang Wei, Rui Chen, Bingshan Li, Christine Y. Kim, Donna C. Ferguson, James L. Netterville, Sarah L. Rohde, Carmen C. Solórzano, Lindsay A. Bischoff, Naira Baregamian, Aaron C. Shaver, Mitra Mehrad, Kim A. Ely, Daniel W. Byrne, Thomas P. Stricker, Barbara A. Murphy, Jennifer H. Choe, Luciane T. Kagohara, Elizabeth M. Jaffee, Eric C. Huang, Fei Ye, Ethan Lee, Vivian L. Weiss

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Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: a joint analysis of OnCovid and ESMO-CoCARE registries by Joan Brunet, Josep Tabernero, Salvatore Grisanti, Matteo Lambertini, George Pentheroudakis, Bruno Vincenzi, Dirk Arnold, Juan Aguilar-Company, Paolo Pedrazzoli, Solange Peters, Luis Castelo-Branco, Emanuela Romano, Olivier Michielin, Ramon Salazar, Alessio Cortellini, Rossana Berardi, Aleix Prat, Spyridon Gennatas, Giuseppe Tonini, Urania Dafni, Kevin J Harrington, Paola Queirolo, David J Pinato, Francesca Mazzoni, David Viñal, Gino M Dettorre, Uma Mukherjee, Mark Bower, Alexia Bertuzzi, Ailsa Sita-Lumsden, Federica Biello, Andrea Patriarca, Alessandra Gennari, Maura Rossi, Zoi Tsourti, Vasileios Angelis, Jacobo Rogado, Teresa Alonso-Gordoa, Georgia Dimopoulou, Sylvain Pradervand, Marco Tucci, Fanny Pommeret, Marco Krengli

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Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function by Tianzhong Yang, Victoria E. Jackson, Albert V. Smith, Han Chen, Traci M. Bartz, Colleen M. Sitlani, Bruce M. Psaty, Sina A. Gharib, George T. O’Connor, Josée Dupuis, Jiayi Xu, Kurt Lohman, Yongmei Liu, Stephen B. Kritchevsky, Patricia A. Cassano, Claudia Flexeder, Christian Gieger, Stefan Karrasch, Annette Peters, Holger Schulz, Sarah E. Harris, John M. Starr, Ian J. Deary, Ani Manichaikul, Elizabeth C. Oelsner, R. G. Barr, Kent D. Taylor, Stephen S. Rich, Tobias N. Bonten, Dennis O. Mook-Kanamori, Raymond Noordam, Ruifang Li-Gao, Marjo-Riitta Jarvelin, Matthias Wielscher, Natalie Terzikhan, Lies Lahousse, Guy Brusselle, Stefan Weiss, Ralf Ewert, Sven Gläser, Georg Homuth, Nick Shrine, Ian P. Hall, Martin Tobin, Stephanie J. London, Peng Wei, Alanna C. Morrison

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Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19) by Peter A. McCullough, Paul E. Alexander, Robin Armstrong, Cristian Arvinte, Alan F. Bain, Richard P. Bartlett, Robert L. Berkowitz, Andrew C. Berry, Thomas J. Borody, Joseph H. Brewer, Adam M. Brufsky, Teryn Clarke, Roland Derwand, Alieta Eck, John Eck, Richard A. Eisner, George C. Fareed, Angelina Farella, Silvia N. S. Fonseca, Charles E. Geyer Jr., Russell S. Gonnering, Karladine E. Graves, Kenneth B. V. Gross, Sabine Hazan, Kristin S. Held, H. Thomas Hight, Stella Immanuel, Michael M. Jacobs, Joseph A. Ladapo, Lionel H. Lee, John Littell, Ivette Lozano, Harpal S. Mangat, Ben Marble, John E. McKinnon, Lee D. Merritt, Jane M. Orient, Ramin Oskoui, Donald C. Pompan, Brian C. Procter, Chad Prodromos, Juliana Cepelowicz Rajter, Jean-Jacques Rajter, C. Venkata S. Ram, Salete S. Rios , Harvey A. Risch, Michael J. A. Robb, Molly Rutherford, Martin Scholz, Marilyn M. Singleton, James A. Tumlin, Brian M. Tyson, Richard G. Urso, Kelly Victory, Elizabeth Lee Vliet, Craig M. Wax, Alexandre G. Wolkoff, Vicki Wooll, Vladimir Zelenko

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The role of open abdomen in non-trauma patient: WSES Consensus Paper by Federico Coccolini, Giulia Montori, Marco Ceresoli, Fausto Catena, Ernest E. Moore, Rao Ivatury, Walter Biffl, Andrew Peitzman, Raul Coimbra, Sandro Rizoli, Yoram Kluger, Fikri M. Abu-Zidan, Massimo Sartelli, Marc De Moya, George Velmahos, Gustavo Pereira Fraga, Bruno M. Pereira, Ari Leppaniemi, Marja A. Boermeester, Andrew W. Kirkpatrick, Ron Maier, Miklosh Bala, Boris Sakakushev, Vladimir Khokha, Manu Malbrain, Vanni Agnoletti, Ignacio Martin-Loeches, Michael Sugrue, Salomone Di Saverio, Ewen Griffiths, Kjetil Soreide, John E. Mazuski, Addison K. May, Philippe Montravers, Rita Maria Melotti, Michele Pisano, Francesco Salvetti, Gianmariano Marchesi, Tino M. Valetti, Thomas Scalea, Osvaldo Chiara, Jeffry L. Kashuk, Luca Ansaloni

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Conceptual comparison of constructs as first step in data harmonization: Parental sensitivity, child temperament, and social support as illustrations by Marije L. Verhage, Carlo Schuengel, Annaleena Holopainen, Marian J. Bakermans-Kranenburg, Annie Bernier, Geoffrey L. Brown, Sheri Madigan, Glenn I. Roisman, Mette S. Vaever, Maria S. Wong, Marian J. Bakermans-Kranenburg, Lavinia Barone, Kazuko Y. Behrens, Johanna Behringer, Annie Bernier, Ina Bovenschen, Geoffrey L. Brown, Rosalinda Cassibba, Jude Cassidy, Gabrielle Coppola, Alessandro Costantini, Mary Dozier, Karin Ensink, R. M. Pasco Fearon, Brent Finger, Airi Hautamaki, Nancy L. Hazen, Elena Ierardi, Inês Jongenelen, Simo Køppe, Francesca Lionetti, Sheri Madigan, Sarah Mangelsdorf, Mirjam Oosterman, Cecilia S. Pace, K. Lee Raby, Cristina Riva Crugnola, Glenn I. Roisman, Carlo Schuengel, Alessandra Simonelli, Gottfried Spangler, George M. Tarabulsy, Mette S. Væver, Marije L. Verhage, Maria S. Wong, Bronia Arnott, Heidi Bailey, Patrick J. Brice, Karl-Heinz Brisch, Germana Castoro, Elisabetta Costantino, Chantal Cyr, Carol George, Gabriele Gloger-Tippelt, Sonia Gojman, Susanne Harder, Carollee Howes, Heidi Jacobsen, Deborah Jacobvitz, Mi Kyoung Jin, Femmie Juffer, Miyuki Kazui, Esther M. Leerkes, Karlen Lyons-Ruth, Catherine McMahon, Elizabeth Meins, Salvador Millán, Lynne Murray, Katja Nowacki, David R. Pederson, Lynn Priddis, Avi Sagi-Schwartz, Sarah J. Schoppe-Sullivan, Judith Solomon, Anna Maria Speranza, Miriam Steele, Howard Steele, Doug M. Teti, Marinus H. van IJzendoorn, W. Monique van Londen-Barentsen, Mary J. Ward

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Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity by Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Ian B. Stanaway, PhD, Neha A. Sathe, MD, MSc, Avantika Srivastava, MS, Radu Postelnicu, MD, Richard Green, BS, Adair Andrews, BSN, Martin Gonzalez, BS, Christopher J. Kratochvil, MD, Vishakha K. Kumar, BS, Tien-Ying Hsiang, PhD, Michael Gale, Jr, PhD, George L. Anesi, MD, David Wyles, MD, M. Jana Broadhurst, MD, PhD, David Brett-Major, MD, MPH, Vikramjit Mukherjee, MD, Jonathan E. Sevransky, MD, Douglas Landsittel, PhD, Chi Hung, MD, William A. Altemeier, MD, Sina A. Gharib, MD, Timothy M. Uyeki, MD, MPH, J. Perren Cobb, MD, Janice M. Liebler, MD, David R. Crosslin, PhD, Gail P. Jarvik, MD, Leopoldo N. Segal, MD, Laura Evans, MD, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals by Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Akhil Pampana, David Y. Zhang, Joseph Park, Stella Aslibekyan, Joshua C. Bis, Jennifer A. Brody, Brian E. Cade, Lee-Ming Chuang, Ren-Hua Chung, Joanne E. Curran, Lisa de las Fuentes, Paul S. de Vries, Ravindranath Duggirala, Barry I. Freedman, Mariaelisa Graff, Xiuqing Guo, Nancy Heard-Costa, Bertha Hidalgo, Chii-Min Hwu, Marguerite R. Irvin, Tanika N. Kelly, Brian G. Kral, Leslie Lange, Xiaohui Li, Martin Lisa, Steven A. Lubitz, Ani W. Manichaikul, Preuss Michael, May E. Montasser, Alanna C. Morrison, Take Naseri, Jeffrey R. O’Connell, Nicholette D. Palmer, Patricia A. Peyser, Muagututia S. Reupena, Jennifer A. Smith, Xiao Sun, Kent D. Taylor, Russell P. Tracy, Michael Y. Tsai, Zhe Wang, Yuxuan Wang, Wei Bao, John T. Wilkins, Lisa R. Yanek, Wei Zhao, Donna K. Arnett, John Blangero, Eric Boerwinkle, Donald W. Bowden, Yii-Der Ida Chen, Adolfo Correa, L. Adrienne Cupples, Susan K. Dutcher, Patrick T. Ellinor, Myriam Fornage, Stacey Gabriel, Soren Germer, Richard Gibbs, Jiang He, Robert C. Kaplan, Sharon L. R. Kardia, Ryan Kim, Charles Kooperberg, Ruth J. F. Loos, Karine A Viaud-Martinez, Rasika A. Mathias, Stephen T. McGarvey, Braxton D. Mitchell, Deborah Nickerson, Kari E. North, Bruce M. Psaty, Susan Redline, Alexander P. Reiner, Ramachandran S. Vasan, Stephen S. Rich, Cristen Willer, Jerome I. Rotter, Daniel J. Rader, Xihong Lin, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Gina M. Peloso, Pradeep Natarajan

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WSES consensus conference guidelines: monitoring and management of severe adult traumatic brain injury patients with polytrauma in the first 24 hours by Edoardo Picetti, Sandra Rossi, Fikri M. Abu-Zidan, Luca Ansaloni, Rocco Armonda, Gian Luca Baiocchi, Miklosh Bala, Zsolt J. Balogh, Maurizio Berardino, Walter L. Biffl, Pierre Bouzat, Andras Buki, Marco Ceresoli, Randall M. Chesnut, Osvaldo Chiara, Giuseppe Citerio, Federico Coccolini, Raul Coimbra, Salomone Di Saverio, Gustavo P. Fraga, Deepak Gupta, Raimund Helbok, Peter J. Hutchinson, Andrew W. Kirkpatrick, Takahiro Kinoshita, Yoram Kluger, Ari Leppaniemi, Andrew I. R. Maas, Ronald V. Maier, Francesco Minardi, Ernest E. Moore, John A. Myburgh, David O. Okonkwo, Yasuhiro Otomo, Sandro Rizoli, Andres M. Rubiano, Juan Sahuquillo, Massimo Sartelli, Thomas M. Scalea, Franco Servadei, Philip F. Stahel, Nino Stocchetti, Fabio S. Taccone, Tommaso Tonetti, George Velmahos, Dieter Weber, Fausto Catena

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Declaración de posición del Grupo de la Comisión Lancet de Hipertensión con respecto a la mejora mundial de las normas de exactitud para los dispositivos de medición de la presión... by James E. Sharman, Eoin O’Brien, Bruce Alpert, Aletta E. Schutte, Christian Delles, Michael Hecht Olsen, Roland Asmar, Neil Atkins, Eduardo Barbosa, David Calhoun, Norm R.C. Campbell, John Chalmers, Ivor Benjamin, Garry Jennings, Stéphane Laurent, Pierre Boutouyrie, Patricio Lopez-Jaramillo, Richard J. McManus, Anastasia S. Mihailidou, Pedro Ordunez, Raj Padwal, Paolo Palatini, Gianfranco Parati, Neil Poulter, Michael K. Rakotz, Clive Rosendorff, Francesca Saladini, Angelo Scuteri, Weimar Sebba Barroso, Myeong-Chan Cho, Ki-Chul Sung, Raymond R. Townsend, Ji-Guang Wang, Tine Willum Hansen, Gregory Wozniak, George Stergiou

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