α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies by Matthias Schmitz, Niccolò Candelise, Sezgi Canaslan, Hermann C. Altmeppen, Jakob Matschke, Markus Glatzel, Neelam Younas, Saima Zafar, Peter Hermann, Inga Zerr

Get full text

Corrigendum: White Matter Changes-Related Gait and Executive Function Deficits: Associations with Age and Parkinson's Disease by Jennifer Sartor, Jennifer Sartor, Kristina Bettecken, Kristina Bettecken, Felix P. Bernhard, Felix P. Bernhard, Marc Hofmann, Till Gladow, Tobias Lindig, Meltem Ciliz, Meltem Ciliz, Mara ten Kate, Johanna Geritz, Sebastian Heinzel, Marije Benedictus, Philip Scheltens, Markus A. Hobert, Markus A. Hobert, Markus A. Hobert, Walter Maetzler, Walter Maetzler, Walter Maetzler

Get full text

Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation by Bikash Choudhary, Eckhard Mandelkow, Eva-Maria Mandelkow, Ghulam Jeelani Pir

Get full text

Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98 by Lisa Diez, Larisa E. Kapinos, Janine Hochmair, Sabrina Huebschmann, Alvaro Dominguez-Baquero, Amelie Vogt, Marija Rankovic, Markus Zweckstetter, Roderick Y. H. Lim, Susanne Wegmann

Get full text

Propagation and Dissemination Strategies of Transmissible Spongiform Encephalopathy Agents in Mammalian Cells by Stefanie-Elisabeth Heumüller, Annika C. Hornberger, Alina S. Hebestreit, André Hossinger, Ina M. Vorberg

Get full text

L-lactate exerts a pro-proliferative effect on adult hippocampal precursor cells in vitro by Alexandra Pötzsch, Sara Zocher, Stefanie N. Bernas, Odette Leiter, Annette E. Rünker, Gerd Kempermann

Get full text

Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice by Luisa Strackeljan, Ewa Baczynska, Carla Cangalaya, David Baidoe-Ansah, Jakub Wlodarczyk, Rahul Kaushik, Alexander Dityatev

Get full text

Anti-aggregant tau mutant promotes neurogenesis by Maria Joseph, Marta Anglada-Huguet, Katharina Paesler, Eckhard Mandelkow, Eva-Maria Mandelkow

Get full text

Inhibition of Tau aggregation with BSc3094 reduces Tau and decreases cognitive deficits in rTg4510 mice by Marta Anglada‐Huguet, Sara Rodrigues, Katja Hochgräfe, Eckhard Mandelkow, Eva‐Maria Mandelkow

Get full text

TRPC4 Channel Knockdown in the Hippocampal CA1 Region Impairs Modulation of Beta Oscillations in Novel Context by Babak Saber Marouf, Antonio Reboreda, Frederik Theissen, Rahul Kaushik, Magdalena Sauvage, Alexander Dityatev, Motoharu Yoshida

Get full text

Structural and diffusion imaging versus clinical assessment to monitor amyotrophic lateral sclerosis by Arturo Cardenas-Blanco, Judith Machts, Julio Acosta-Cabronero, Joern Kaufmann, Susanne Abdulla, Katja Kollewe, Susanne Petri, Stefanie Schreiber, Hans-Jochen Heinze, Reinhard Dengler, Stefan Vielhaber, Peter J. Nestor

Get full text

Supporting elderly people with cognitive impairment during and after hospital stays with intersectoral care management: study protocol for a randomized controlled trial by Angela Nikelski, Armin Keller, Fanny Schumacher-Schönert, Terese Dehl, Jessica Laufer, Ulf Sauerbrey, Diana Wucherer, Adina Dreier-Wolfgramm, Bernhard Michalowsky, Ina Zwingmann, Horst Christian Vollmar, Wolfgang Hoffmann, Stefan H. Kreisel, Jochen René Thyrian

Get full text

Hsp multichaperone complex buffers pathologically modified Tau by Antonia Moll, Lisa Marie Ramirez, Momchil Ninov, Juliane Schwarz, Henning Urlaub, Markus Zweckstetter

Get full text

Evidence for allocentric boundary and goal direction information in the human entorhinal cortex and subiculum by J. P. Shine, J. P. Valdés-Herrera, C. Tempelmann, T. Wolbers

Get full text

Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease by Isabelle Arnoux, Michael Willam, Nadine Griesche, Jennifer Krummeich, Hirofumi Watari, Nina Offermann, Stephanie Weber, Partha Narayan Dey, Changwei Chen, Olivia Monteiro, Sven Buettner, Katharina Meyer, Daniele Bano, Konstantin Radyushkin, Rosamund Langston, Jeremy J Lambert, Erich Wanker, Axel Methner, Sybille Krauss, Susann Schweiger, Albrecht Stroh

Get full text

Cognitive Profiles of Amyotrophic Lateral Sclerosis Differ in Resting-State Functional Connectivity: An fMRI Study by Anna G. M. Temp, Martin Dyrba, Charlotte Büttner, Elisabeth Kasper, Judith Machts, Judith Machts, Jörn Kaufmann, Stefan Vielhaber, Stefan Vielhaber, Stefan Teipel, Stefan Teipel, Johannes Prudlo, Johannes Prudlo

Get full text

Sonographic and 3T-MRI-based evaluation of the tongue in ALS by Nathalie Hensiek, Frank Schreiber, Thomas Wimmer, Jörn Kaufmann, Judith Machts, Laura Fahlbusch, Cornelia Garz, Susanne Vogt, Johannes Prudlo, Reinhard Dengler, Susanne Petri, Peter J. Nestor, Stefan Vielhaber, Stefanie Schreiber

Get full text

Depletion and activation of microglia impact metabolic connectivity of the mouse brain by Johannes Gnörich, Anika Reifschneider, Karin Wind, Artem Zatcepin, Sebastian T. Kunte, Philipp Beumers, Laura M. Bartos, Thomas Wiedemann, Maximilian Grosch, Xianyuan Xiang, Maryam K. Fard, Francois Ruch, Georg Werner, Mara Koehler, Luna Slemann, Selina Hummel, Nils Briel, Tanja Blume, Yuan Shi, Gloria Biechele, Leonie Beyer, Florian Eckenweber, Maximilian Scheifele, Peter Bartenstein, Nathalie L. Albert, Jochen Herms, Sabina Tahirovic, Christian Haass, Anja Capell, Sibylle Ziegler, Matthias Brendel

Get full text

Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes by Elisabeth Findeiss, Elisabeth Findeiss, Sigrid C. Schwarz, Valentin Evsyukov, Valentin Evsyukov, Valentin Evsyukov, Thomas W. Rösler, Thomas W. Rösler, Matthias Höllerhage, Matthias Höllerhage, Matthias Höllerhage, Tasnim Chakroun, Tasnim Chakroun, Niko-Petteri Nykänen, Niko-Petteri Nykänen, Yimin Shen, Wolfgang Wurst, Wolfgang Wurst, Wolfgang Wurst, Michael Kohl, Jörg Tost, Günter U. Höglinger, Günter U. Höglinger, Günter U. Höglinger

Get full text

An iPSC model for POLR3A-associated spastic ataxia: Generation of three unrelated patient cell lines by Kalaivani Manibarathi, Tam Pham, Holger Hengel, Matthis Synofzik, Maike Nagel, Rebecca Schüle

Get full text