Bioequivalence study of abacavir/lamivudine (600/300-mg) tablets in healthy Thai volunteers under fasting conditions by Ekawan Yoosakul, Jaturavit Vattanarongkup, Chutima Manamuti, Bancha Chuasuwan, Isariya Techatanawat, Busarat Karachot, Porranee Puranajoti

Get full text

Evaluation of previous product residue on magnetic bar used for manufacturing of Japanese Encephalitis vaccine by Ratiya Kukhetpitakwong, Worawit Sangamrum, Kornkaew Laima, Tassanee Damriram, Tulyaluck Aupaichit, Karuna Tuncharoen, Boonrak Thawornrungroaj

Get full text

Anti-proliferative and apoptotic effect of cannabinoids on human pancreatic ductal adenocarcinoma xenograft in BALB/c nude mice model by Trung Quang Le, Nuntana Meesiripan, Suleeporn Sanggrajang, Nuntakan Suwanpidokkul, Piyaporn Prayakprom, Chatchada Bodhibukkana, Vipada Khaowroongrueng, Kankanit Suriyachan, Somchai Thanasitthichai, Attasit Srisubat, Pattamaporn Surawongsin, Anudep Rungsipipat, Siriwan Sakarin, Kasem Rattanapinyopituk

Get full text

Antitumor Effects of Cannabinoids in Human Pancreatic Ductal Adenocarcinoma Cell Line (Capan-2)-Derived Xenograft Mouse Model by Siriwan Sakarin, Nuntana Meesiripan, Suleeporn Sangrajrang, Nuntakan Suwanpidokkul, Piyaporn Prayakprom, Chatchada Bodhibukkana, Vipada Khaowroongrueng, Kankanit Suriyachan, Somchai Thanasittichai, Attasit Srisubat, Pattamaporn Surawongsin, Kasem Rattanapinyopituk

Get full text

Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase 1 tr... by Punnee Pitisuttithum, Viravarn Luvira, Saranath Lawpoolsri, Sant Muangnoicharoen, Supitcha Kamolratanakul, Chaisith Sivakorn, Piengthong Narakorn, Somchaiya Surichan, Sumalee Prangpratanporn, Suttida Puksuriwong, Steven Lamola, Laina D. Mercer, Rama Raghunandan, Weina Sun, Yonghong Liu, Juan Manuel Carreño, Rami Scharf, Weerapong Phumratanaprapin, Fatima Amanat, Luc Gagnon, Ching-Lin Hsieh, Ruangchai Kaweepornpoj, Sarwat Khan, Manjari Lal, Stephen McCroskery, Jason McLellan, Ignacio Mena, Marcia Meseck, Benjaluck Phonrat, Yupa Sabmee, Ratsamikorn Singchareon, Stefan Slamanig, Nava Suthepakul, Johnstone Tcheou, Narumon Thantamnu, Sompone Theerasurakarn, Steven Tran, Thanakrit Vilasmongkolchai, Jessica A White, Nina Bhardwaj, Adolfo Garcia-Sastre, Peter Palese, Florian Krammer, Kittisak Poopipatpol, Ponthip Wirachwong, Richard Hjorth, Bruce L Innis

Get full text

A review of epidemic preparedness for influenza through local vaccine production: national security for Thailand by Punnee Pitisuttithum, Ponthip Wirachwong

“…With the support of WHO, the Thai Government Pharmaceutical Organization (GPO) as the developed local production capacity of influenza vaccines. …”
Get full text

Assessment of safety and intranasal neutralizing antibodies of HPMC-based human anti-SARS-CoV-2 IgG1 nasal spray in healthy volunteers by Thanarath Imsuwansri, Thitinan Jongthitinon, Niramon Pojdoung, Nuntana Meesiripan, Siriwan Sakarin, Chatikorn Boonkrai, Tossapon Wongtangprasert, Tanapati Phakham, Thittaya Audomsun, Chadaporn Attakitbancha, Pijitra Saelao, Phijitra Muanwien, Maoxin Tim Tian, Songsak Tongchusak, Bhrus Sangruji, Dhammika Leshan Wannigama, Chenphop Sawangmake, Watchareewan Rodprasert, Quynh Dang Le, Steven Dwi Purbantoro, Kananuch Vasuntrarak, Sirirat Nantavisai, Supakit Sirilak, Ballang Uppapong, Sompong Sapsutthipas, Sakalin Trisiriwanich, Thitiporn Somporn, Asmah Usoo, Natthakarn Mingngamsup, Supaporn Phumiamorn, Porawan Aumklad, Kwanputtha Arunprasert, Prasopchai Patrojanasophon, Praneet Opanasopit, Norapath Pesirikan, Ladda Nitisaporn, Jesada Pitchayakorn, Thana Narkthong, Bancha Mahong, Kumchol Chaiyo, Kanjana Srisutthisamphan, Ratchanont Viriyakitkosol, Songklot Aeumjaturapat, Anan Jongkaewwattana, Sakarn Bunnag, Trairak Pisitkun

Get full text

Scale-Up Synthesis and In Vivo Anti-Tumor Activity of Curcumin Diethyl Disuccinate, an Ester Prodrug of Curcumin, in HepG2-Xenograft Mice by Chawanphat Muangnoi, Pahweenvaj Ratnatilaka Na Bhuket, Ponsiree Jithavech, Wisut Wichitnithad, Onsiri Srikun, Chakkrapan Nerungsi, Suthiluk Patumraj, Pornchai Rojsitthisak

Get full text

Pharmacokinetics of three commercial antivenoms in patients envenomed by the Malayan pit viper, Calloselasma rhodostoma, in Thailand. by Ho, M, Silamut, K, White, N, Karbwang, J, Looareesuwan, S, Phillips, R, Warrell, D

“…This was marked for antivenom from the Government Pharmaceutical Organization of Thailand which contained mostly F(ab)2 fragments. …”

Randomized comparative trial of three monospecific antivenoms for bites by the Malayan pit viper (Calloselasma rhodostoma) in southern Thailand: clinical and laboratory correlation... by Warrell, D, Looareesuwan, S, Theakston, R, Phillips, R, Chanthavanich, P, Viravan, C, Supanaranond, W, Karbwang, J, Ho, M, Hutton, R

“…Forty-six patients with proved MPV bites and incoagulable blood, indicating systemic envenoming, were randomly allocated for treatment with Thai Red Cross (TRC), Thai Government Pharmaceutical Organization (GPO), or Twyford Pharmaceutical monospecific antivenoms. …”

Health Impact Assessment of Pesticide Use in Northern Thai Farmers by Ratana Sapbamrer, Arrak Damrongsat, Prajak Kongtan

“…Regarding determination of cholinesterase activity by rapid test from The Government Pharmaceutical Organization, 23.5 % of farmers had pesticide residues in serum at safe level, 55.1 % at risk level, and 21.3% at unsafe level. …”
Get full text

Health Impact Assessment of Pesticide Use in Northern Thai Farmers by Ratana Sapbamrer, Arrak Damrongsat, Prajak Kongtan

“…Regarding determination of cholinesterase activity by rapid test from The Government Pharmaceutical Organization, 23.5 % of farmers had pesticide residues in serum at safe level, 55.1 % at risk level, and 21.3% at unsafe level. …”
Get full text

A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses by Weina Sun, Yonghong Liu, Fatima Amanat, Irene González-Domínguez, Stephen McCroskery, Stefan Slamanig, Lynda Coughlan, Victoria Rosado, Nicholas Lemus, Sonia Jangra, Raveen Rathnasinghe, Michael Schotsaert, Jose L. Martinez, Kaori Sano, Ignacio Mena, Bruce L. Innis, Ponthip Wirachwong, Duong Huu Thai, Ricardo Das Neves Oliveira, Rami Scharf, Richard Hjorth, Rama Raghunandan, Florian Krammer, Adolfo García-Sastre, Peter Palese

Get full text

Efficiency Comparative Approach of Plant-Produced Monoclonal Antibodies against Rabies Virus Infection by Boonlert Lumlertdacha, Bancha Mahong, Kaewta Rattanapisit, Christine Joy I. Bulaon, Thiravat Hemachudha, Waranyoo Phoolcharoen

Get full text

Genetic diversity and phylogenetic analyses of Asian lineage Zika virus whole genome sequences derived from Culex quinquefasciatus mosquitoes and urine of patients during the 2020... by Atchara Phumee, Suwalak Chitcharoen, Nataya Sutthanont, Proawpilart Intayot, Supaporn Wacharapluesadee, Padet Siriyasatien

Get full text

Effects of Acanthus ebracteatus Vahl on tumor angiogenesis and on tumor growth in nude mice implanted with cervical cancer by Mahasiripanth T, Hokputsa S, Niruthisard S, Bhattarakosol P, Patumraj S

“…Taksanee Mahasiripanth,1 Sanya Hokputsa,2 Somchai Niruthisard,3 Parvapan Bhattarakosol,4 Suthiluk Patumraj51Inter-Department of Physiology, Chulalongkorn University, Bangkok, Thailand; 2Research and Development Institute, Government Pharmaceutical Organization, Bangkok, Thailand; 3Obstetrics and Gynecology Department, 4Department of Microbiology, 5Center of Excellence for Microcirculation, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandPurpose: The aim of this study was to examine the effects of the crude extract of Acanthus ebracteatus Vahl (AE) on tumor growth and angiogenesis by utilizing a tumor model in which nude mice were implanted with cervical cancer cells containing human papillomavirus 16 DNA (HPV-16 DNA).Materials and methods: The growth-inhibitory effect of AE was investigated in four different cell types: CaSki (HPV-16 positive), HeLa (HPV-18 positive), hepatocellular carcinoma cells (HepG2), and human dermal fibroblast cells (HDFs). …”
Get full text

T cell mediated immunity against influenza H5N1 nucleoprotein, matrix and hemagglutinin derived epitopes in H5N1 survivors and non-H5N1 subjects by Pirom Noisumdaeng, Thaneeya Roytrakul, Jarunee Prasertsopon, Phisanu Pooruk, Hatairat Lerdsamran, Susan Assanasen, Rungrueng Kitphati, Prasert Auewarakul, Pilaipan Puthavathana

Get full text

Description of potential vectors of zoonotic filarial nematodes, Brugia pahangi, Setaria digitata, and Setaria labiatopapillosa in Thai mosquitoes by Padet Siriyasatien, Proawpilart Intayot, Vorthon Sawaswong, Kanok Preativatanyou, Supaporn Wacharapluesadee, Rungfar Boonserm, Sriwatapron Sor-suwan, Pattama Ayuyoe, Ana Cantos-Barreda, Atchara Phumee

Get full text

Iron-chelating and anti-lipid peroxidation properties of 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one (CM1) in long-term iron loading β-thalassemic mice by Kanokwan Kulprachakarn, Nittaya Chansiw, Kanjana Pangjit, Chada Phisalaphong, Suthat Fucharoen, Robert C. Hider, Sineenart Santitherakul, Somdet Srichairatanakool

Get full text