Genome insight and probiotic potential of three novel species of the genus Corynebacterium by Md Shamsuzzaman, Ram Hari Dahal, Shukho Kim, Shukho Kim, Jungmin Kim, Jungmin Kim

“…They were able to grow within a temperature range of 10–42°C (optimum, 32–37°C), at a pH range of 2.0–10.0 (optimum, pH 5.5–8.0), and at NaCl concentration of 0.5–10.5% (w/v). …”
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A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy by Junzhong Lai, Jiadi Liang, Yong Zhang, Bingchen Zhang, Jianhui Wei, Jiqiang Fan, Linqin Chen, Zhirong Chen, Qiumei Li, Dong Guo, Jizhen Lin, Qi Chen

“…Our findings have unveiled that CS-Zeb NPs manifest heightened drug release within an acidic milieu (pH 5.5) in comparison to a neutral environment (pH 7.4). …”
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Microneedle-coupled epidermal sensors for in-situ-multiplexed ion detection in interstitial fluids by Zhu, Dan Dan, Tan, Yu Rong, Zheng, Lewen, Lao, Jia Zheng, Liu, Ji Yang, Yu, Jing, Chen, Peng

“…The potentiometric sensor can simultaneously detect these ion species with nearly Nernstian response, in the ranges wider enough for diagnosis purposes (Na+: 0.75-200 mM, K+: 1-128 mM, Ca2+: 0.25-4.25 mM, pH: 5.5-8.5). The in vivo experiments on mice, human, and plants demonstrate the feasibility of MNP-EA for timely and convenient diagnosis of ion imbalances with minimal invasiveness. …”
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Reductive dechlorination under acidic condition by Jiang, Xie

“…In this project, the anaerobic sequencing batch reactor (anSBR) was acclimated and operated at pH 5.5. The reduction of pH followed the step-wise reduction manner at the rate of 0.5 per week. …”
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Polyvinyl alcohol-grafted-multiwalled carbon nanotubes as a delivery system for curcumin in H2O2-induced damaged neuroblastoma SH-SY5Y cells by Zawawi, Nurliyana Ahmad

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Crystallization and structure elucidation of recombinant Pseudomonas aeruginosa strain K solvent tolerant elastase by Mat Said, Zatty Syamimi@Adura

“…The highly purified elastase strain K with protein concentration around 3.00 mg/mL and pH 5.5 is the optimal condition for crystal growth. …”
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Enzymatic Hydrolysis of Sago Starch for the Production of Maltodextrins by Ch'ng, Yan Eng

“…A starch concentration of 20% (w/v) was suitable for hydrolysis at pH 5.5 to pH 6.5. Optimum Termamyl 120L dosages were 0.08 to 0.10% (w/w) for the production of DE 6 to 20 maltodextrins. …”
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Effects of palm oil mill effluent anaerobic sludge pretreatment temperature on biohydrogen production and the inoculum microbial community by Dzulkarnain, Eka Latiffah Nadia

“…Biohydrogen production was evaluated under batch fermentation (30°C, initial pH 5.5-6.0, 180 rpm). Shotgun metagenomics analysis was carried out on the raw, untreated and treated sludge inoculum after fermentation. …”
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Polyvinyl alcohol-grafted-multiwalled carbon nanotubes as a delivery system for curcumin in H2O2-induced damaged neuroblastoma SH-SY5Y cells by Ahmad Zawawi, Nurliyana

“…Although Curcumin adsorption on PVA-MWCNT was only at minimal amount, it showed the most efficient desorption occurred at pH 5.5 (25%) rather than pH 7.4 (3%) with sustained release over a 3-day incubation. …”
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An Overview of Rice Cultivation in Spain and the Management of Herbicide-Resistant Weeds by Diego Gómez de Barreda, Gabriel Pardo, José María Osca, Mar Catala-Forner, Silvia Consola, Irache Garnica, Nuria López-Martínez, José Antonio Palmerín, Maria Dolores Osuna

“…The main soil texture throughout Spanish rice areas is silty clay loam, with alkaline soils (pH > 7.5)—except in the Extremadura area (pH = 5.5–6)—and a low organic matter content. Water quality in terms of salinity is acceptable, although in some coastal rice areas salinity issues occasionally appear to be a determining factor for high yield achievement. …”
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Enhanced in vivo blood brain barrier transcytosis of macromolecular cargo using an engineered pH-sensitive mouse transferrin receptor binding nanobody by Thomas J. Esparza, Shiran Su, Caroline M. Francescutti, Elvira Rodionova, Joong Hee Kim, David L. Brody

“…Methods A mouse transferrin receptor binding nanobody, NIH-mTfR-M1, was engineered to confer greater unbinding at pH 5.5 vs 7.4 by introducing multiple histidine mutations. …”
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A single-point mutation in the rubella virus E1 glycoprotein promotes rescue of recombinant vesicular stomatitis virus by Pratyush Kumar Das, Paulina Alatriste Gonzalez, Rohit K. Jangra, Peiqi Yin, Margaret Kielian

“…However, the E1 W448R mutation strongly shifted the threshold for the acid pH-triggered virus fusion reaction, from pH 6.2 for the WT RuV to pH 5.5 for the mutant. These results suggest that the increased resistance of the mutant RuV E1 to acidic pH promotes the ability of viral envelope proteins to generate infectious rVSV and provide insights into the regulation of RuV fusion during virus entry and exit.IMPORTANCERubella virus (RuV) infection in pregnant women can cause miscarriage or severe fetal birth defects. …”
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Tumor integrin targeted theranostic iron oxide nanoparticles for delivery of caffeic acid phenethyl ester: preparation, characterization, and anti-myeloma activities by Barkley Smith, Yuancheng Li, Yuancheng Li, Travis Fields, Michael Tucker, Anna Staskiewicz, Erica Wong, Handong Ma, Hui Mao, Xinyu Wang

“…The drug-release studies indicate RGD-IONP/CAPE is stable at physiological (pH 7.4) and basic pH (pH 9.5) and subject to release of CAPE at acidic pH (pH 5.5) mimicking the tumor and lysosomal condition. …”
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Phytosterol-Loaded Surface-Tailored Bioactive-Polymer Nanoparticles for Cancer Treatment: Optimization, In Vitro Cell Viability, Antioxidant Activity, and Stability Studies by Shahid Karim, Md Habban Akhter, Abdulhadi S. Burzangi, Huda Alkreathy, Basma Alharthy, Sabna Kotta, Shadab Md, Md Abdur Rashid, Obaid Afzal, Abdulmalik S. A. Altamimi, Habibullah Khalilullah

“…The maximum β-SIT release from β-SIT-Alg/Ch-NPs-FA was 71.50 ± 6.5% in pH 5.5. The cytotoxic assay expressed an extremely significant antitumor effect by β-SIT-Alg/Ch-NPs-FA when compared to β-SIT-suspension (<i>p</i> < 0.001). …”
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Mechanical recanalization in ischemic anterior circulation stroke within an 8-hour time window: a real-world experience by Dagmar Krajíčková, Antonín Krajina, Roman Herzig, Miroslav Lojík, Vendelín Chovanec, Jan Raupach, Eva Vítková, Jan Waishaupt, Oldřich Vyšata, Martin Vališ

“…Good 3-month clinical outcome was achieved in 61 patients (55.5%): in 46 patients treated within 6 h (55.4%), 5 patients treated within 6–8 h (45.5%), and 10 patients with unknown onset time (62.5%). …”
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MOF/polypeptide hybrid nanocomposites with pH/lipase dual responsive drug release and photodynamic effect for combination treatment of drug-resistant bacterial infection by Ya-li Xiang, Shuang-hui Huang, De-yu Tang, Peng-cheng Zhang, Yuan Yong, Qing-han Zhou

“…The pH/lipase dual responsive drug release showed that up to 99.4% CIP and 76.0 % MB were released at pH 5.5 in the presence of lipase from the ZIF/PGA-C/M. …”
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Spatial-temporal Variation and Driving Factors of Soil pH in Typical Cigar Area of Southwest China over the Past 35 Years by Yue HU, Hongzhu FAN, Yong CHEN, Xiao ZHANG, Yunkang LEI, Fucheng LI, Wengqiang FENG

“…In 2019, the area of weakly acidic and neutral soils accounted for 95.25%, and the area of acidic soils (pH < 5.5) accounted for 4.75%, which were mainly distributed in the towns of Majing, Mazu, Hefeng, Nanquan and Shigu. …”
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Encapsulation and Controlled Release of Resveratrol Within Functionalized Mesoporous Silica Nanoparticles for Prostate Cancer Therapy by Zanib Chaudhary, Zanib Chaudhary, Sugarniya Subramaniam, Sugarniya Subramaniam, Sugarniya Subramaniam, Gul Majid Khan, Muhammad Mustafa Abeer, Zhi Qu, Taskeen Janjua, Tushar Kumeria, Tushar Kumeria, Tushar Kumeria, Jyotsna Batra, Jyotsna Batra, Jyotsna Batra, Amirali Popat, Amirali Popat, Amirali Popat

“…On the other hand, PO3-MSNs showed significantly slower release kinetics with only 50% drug release in first 12 h at pH 7.4. At pH 5.5, however, both the PO3-MSNs and NH2-MSNs showed significant control over release (around 40% less release compared with free RES in 24 h). …”
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A New Expression System Based on Psychrotolerant <i>Debaryomyces macquariensis</i> Yeast and Its Application to the Production of Cold-Active β-<span style="font-variant: small-cap... by Marta Wanarska, Ewelina Krajewska-Przybyszewska, Monika Wicka-Grochocka, Hubert Cieśliński, Anna Pawlak-Szukalska, Aneta M. Białkowska, Marianna Turkiewicz, Tomasz Florczak, Ewa Gromek, Joanna Krysiak, Natalia Filipowicz

“…The optimal physical culture conditions for <i>D. macquariensis</i> D50 in a fermenter are as follows: temperature 20 °C, pH 5.5, aeration rate of 1.5 vvm, and a stirring speed of 300 rpm. …”
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Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking by Bridget Lins-Austin, Saajan Patel, Mario Mietzsch, Dewey Brooke, Antonette Bennett, Balasubramanian Venkatakrishnan, Kim Van Vliet, Adam N. Smith, Joanna R. Long, Robert McKenna, Mark Potter, Barry Byrne, Sanford L. Boye, Brian Bothner, Regine Heilbronn, Mavis Agbandje-McKenna

“…Negative-stain EM visualization of liposomes in the presence of capsids at pH 5.5 or when heat shocked showed induced remodeling consistent with the externalization of the PLA₂ domain of VP1u. …”
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