Early antiretroviral therapy is associated with better viral suppression and less HIV drug resistance after implementation of universal treatment in South Africa by Dorward, J, Drain, PK, Osman, F, Sookrajh, Y, Pillay, M, Moodley, P, Garrett, N

“…We performed a cross-sectional analysis among HIV-positive adults who had a viral load taken at 6 months after first-line ART initiation in a South African public clinic. Retrospective HIV drug resistance testing was performed on all samples with a viral load >1,000 copies/mL. …”

A randomized controlled trial of genotypic HIV drug resistance testing in HIV-1-infected children: the PERA (PENTA 8) trial. by Green, H, Gibb, D, Compagnucci, A, Giacomet, V, de Rossi, A, Harper, L, Saïdi, Y, Castelli-Gattinara, G, Pillay, D, Babiker, A, Aboulker, J, Lyall, H, Bacheler, LT, Walker, A, Debré, M, Rosso, R, Burger, D, Della Negra, M, Dunn, D, Giaquinto, C

HIV drug resistance mutations in non-B subtypes after prolonged virological failure on NNRTI-based first-line regimens in sub-Saharan Africa by Kityo, C, Thompson, J, Nankya, I, Hoppe, A, Ndashimye, E, Warambwa, C, Mambule, I, van Oosterhout, J, Wools-Kaloustian, K, Bertagnolio, S, Easterbrook, P, Mugyenyi, P, Walker, A, Paton, N, For the Europe Africa Research Network for Evaluation of Second-line Therapy (EARNEST)Trial Team

Low Prevalence of Pre-Treatment and Acquired Drug Resistance to Dolutegravir among Treatment Naïve Individuals Initiating on Tenofovir, Lamivudine and Dolutegravir in Zimbabwe by Vinie Kouamou, Tendai Washaya, Chiratidzo Ellen Ndhlovu, Justen Manasa

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Rapid emergence of resistance to antiretroviral treatment after undisclosed prior exposure: A case report by Theresa M. Rossouw, Gisela van Dyk, Gert van Zyl

Subjects: “…HIV drug resistance…”
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PREVALENCE OF DRUG RESISTANT HIV STRAINS IN HIV-INFECTED PATIENTS OF REPRODUCTIVE AGE by N. Babii

Subjects: “…HIV, drug resistant mutations, antiretroviral therapy…”
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Rates and Correlates of Short Term Virologic Response among Treatment-Naïve HIV-Infected Children Initiating Antiretroviral Therapy in Ethiopia: A Multi-Center Prospective Cohort S... by Birkneh Tilahun Tadesse, Adugna Chala, Jackson Mukonzo, Tolosssa Eticha Chaka, Sintayehu Tadesse, Eyasu Makonnen, Zabrina L. Brumme, Chanson J. Brumme, Eleni Aklillu

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Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe by Linda A. Mandikiyana Chirimuta, Margaret J. Pascoe, Sara Lowe

Subjects: “…hiv drug resistance…”
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Prevalence of viral load suppression and acquired drug resistance among people living with HIV in Nepal: a nationally representative surveillance study by Keshab Deuba, Gopal Panta, Rajesh Man Rajbhandari, Rajyashree Kunwar, Tara Nath Pokhrel, Lok Raj Pandey, Don Changsom, Siriphan Saeng-aroon, Sanjay Kumar Thakur

Subjects: “…Acquired HIV drug resistance…”
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Comparison of predicted susceptibility between genotype and virtual phenotype HIV drug resistance interpretation systems among treatment-naive HIV-infected patients in Asia: TASER-M cohort analysis by Jiamsakul, A., Kantor, R., Li, P.C., Sirivichayakul, S., Sirisanthana, T., Kantipong, P., Lee, C.K., Kamarulzaman, A., Ratanasuwan, W., Ditangco, R., Singtoroj, T., Sungkanuparph, S.

“…Background: Accurate interpretation of HIV drug resistance (HIVDR) testing is challenging, yet important for patient care. …”
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Bictegravir/emtricitabine/tenofovir alafenamide ensures high rates of virological suppression maintenance despite previous resistance in PLWH who optimize treatment in clinical pra... by Daniele Armenia, Federica Forbici, Ada Bertoli, Giulia Berno, Vincenzo Malagnino, Roberta Gagliardini, Vanni Borghi, William Gennari, Stefania Cicalini, Annarita Buonomini, Elisabetta Teti, Simone Lanini, Alessandra Latini, Loredana Sarmati, Cristina Mussini, Massimo Andreoni, Andrea Antinori, Carlo F. Perno, Francesca Ceccherini-Silberstein, Maria M. Santoro

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Genotypic resistance testing improves antiretroviral treatment outcomes in a cohort of adolescents in Cameroon: Implications in the dolutegravir‑era by Willy Le Roi Togna Pabo, Debimeh Njume, Roland Ndip Ndip, Desiré Takou, Maria-Mercedes Santoro, Collins Chenwi, Grace Beloumou, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Aude Christelle Ka'e, Georges Teto, Beatrice Dambaya, Sandrine Djupsa, Raymond Babila Nyasa, Davy Hyacinthe Gouissi Anguechia, Cedric Kamta, Lionel Bala, Virginie Lambo, Samuel Martin Sosso, Vittorio Colizzi, Carlo Federico Perno, Joseph Fokam, Alexis Ndjolo

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HIV Drug Resistance Patterns and Characteristics Associated with Clinically Significant Drug Resistance among Children with Virologic Failure on Antiretroviral Treatment in Kenya: Findings from the Opt4Kids Randomized Controlled Trial by Lisa Abuogi, Patrick Oyaro, Garoma Wakjira, Katherine K. Thomas, Andrea J. Scallon, Irene Mukui, Bhavna H. Chohan, Evelyn Brown, Enericah Karauki, Nashon Yongo, Bilaal Ahmed, Shukri A. Hassan, James Wagude, Eunice Kinywa, Linda Otieno, Leonard Kingwara, Boaz Oyaro, Lisa M. Frenkel, Grace John-Stewart, Rena C. Patel

“…Increasing HIV drug resistance (DR) among children with HIV (CHIV) on antiretroviral treatment (ART) is concerning. …”
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“I feel drug resistance testing allowed us to make an informed decision”: qualitative insights on the role of HIV drug resistance mutation testing among children and pregnant women living with HIV in western Kenya by Andrea J. Scallon, Shukri A. Hassan, Shirley Rui Qian, Yuandi Gao, Patrick Oyaro, Evelyn Brown, James Wagude, Irene Mukui, Eunice Kinywa, Frederick Oluoch, Francesca Odhiambo, Boaz Oyaro, Leonard Kingwara, Nashon Yongo, Enericah Karauki, Lindah Otieno, Grace C. John-Stewart, Lisa L. Abuogi, Rena C. Patel

“…While many factors contribute to these low rates, the acquisition and development of HIV drug resistance mutations (DRMs) are a contributing factor. …”
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Efficacy of Dolutegravir versus Darunavir in Antiretroviral First-Line Regimens According to Resistance Mutations and Viral Subtype by Pierluigi Francesco Salvo, Damiano Farinacci, Arturo Ciccullo, Vanni Borghi, Stefano Rusconi, Annalisa Saracino, William Gennari, Bianca Bruzzone, Ilaria Vicenti, Annapaola Callegaro, Antonio Di Biagio, Maurizio Zazzi, Simona Di Giambenedetto, Alberto Borghetti

Subjects: “…HIV drug resistance…”
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Drug Resistance Prediction Using Deep Learning Techniques on HIV-1 Sequence Data by Margaret C. Steiner, Keylie M. Gibson, Keith A. Crandall

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Genetic diversity of the human immunodeficiency virus (HIV-1) in the Kaliningrad region by Alexander N. Shchemelev, Aleksandr V. Semenov, Yulia V. Ostankova, Ekaterina V. Naidenova, Elena B. Zueva, Diana E. Valutite, Mariia A. Churina, Pavel A. Virolainen, Areg A. Totolian

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Detection of Patient HIV-1 Drug Resistance Mutations in Russia’s Northwestern Federal District in Patients with Treatment Failure by Alexander N. Shchemelev, Yulia V. Ostankova, Elena B. Zueva, Alexander V. Semenov, Areg A. Totolian

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Virological efficacy of switch to DTG plus 3TC in a retrospective observational cohort of suppressed HIV-1 patients with or without past M184V: the LAMRES study by Maria Mercedes Santoro, Daniele Armenia, Elisa Teyssou, José Ramón Santos, Charlotte Charpentier, Sidonie Lambert-Niclot, Andrea Antinori, Christine Katlama, Diane Descamps, Carlo Federico Perno, Vincent Calvez, Roger Paredes, Francesca Ceccherini-Silberstein, Anne Geneviève Marcelin

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Identification of HIV-1 subtype CRF18_cpx in a patient with multidrug resistance in KwaZulu-Natal, South Africa: An epidemiological worry? by Aabida Khan, Melendhran Pillay, Benjamin Chimukangara, Lilishia Gounder, Sontaga Manyana, Kerri-Lee Francois, Knowledge Chipango

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