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Dolutegravir resistance in sub-Saharan Africa: should resource-limited settings be concerned for future treatment?
Published 2023-09-01Subjects: “…HIV drug resistance…”
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Pre-Treatment Integrase Inhibitor Resistance and Natural Polymorphisms among HIV-1 Subtype C Infected Patients in Ethiopia
Published 2022-03-01Subjects: Get full text
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Insights into HIV-1 Transmission Dynamics Using Routinely Collected Data in the Mid-Atlantic United States
Published 2022-12-01Subjects: Get full text
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86
Preexposure prophylaxis will have a limited impact on HIV-1 drug resistance in sub-Saharan Africa: a comparison of mathematical models
Published 2013“…Preexposure prophylaxis (PrEP) with tenofovir and emtricitabine can prevent new HIV-1 infections, but there is a concern that use of PrEP could increase HIV drug resistance resulting in loss of treatment options. …”
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A Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections
Published 2023-07-01Get full text
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HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis
Published 2024-02-01“…Background: There are an increasing number of articles focused on the prevalence and clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing (SGS). …”
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Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research
Published 2018“…Clinical trials, cohorts and surveillance of HIV drug resistance will be required to answer these questions and to maximise the benefits of this new regimen.…”
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Point-of-care testing, new antiretroviral regimens and community-based treatment to enhance primary care HIV services in South Africa
Published 2022“…However, there are new challenges in a) providing HIV viral load testing to monitor the effectiveness of ART, b) combating HIV drug resistance, and c) efficiently providing treatment to the 39 million people living with HIV globally. …”
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HIV-1 pretreatment drug resistance and genetic transmission network in the southwest border region of China
Published 2022-09-01“…Abstract Background HIV drug resistance increased with the widespread use of antiretroviral drugs, and posed great threat to antiretroviral therapy (ART). …”
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Different frequencies of drug resistance mutations among HIV-1 subtypes circulating in China: a comprehensive study.
Published 2014-01-01“…The rapid spreading of HIV drug resistance is threatening the overall success of free HAART in China. …”
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Quality Control of Next-Generation Sequencing-Based HIV-1 Drug Resistance Data in Clinical Laboratory Information Systems Framework
Published 2020-06-01“…Here, we focus in particular on the quality control measures applied on the final sequencing product aligned with the recommendations from the World Health Organization HIV Drug Resistance Laboratory Network.…”
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Analysis of prevalence of HIV-1 primary resistance to antiretroviral drugs in the territory of Moscow and Moscow region
Published 2019-08-01“…To analyze the level of HIV drug resistance among primary patients (who did not receive antiretroviral therapy (ART)) living in the Moscow region, where access to the antiretroviral therapy is quite high.Material and methods. …”
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Retrospective Study on Genetic Diversity and Drug Resistance among People Living with HIV at an AIDS Clinic in Beijing
Published 2024-01-01“…Nested polymerase chain reaction (PCR) was utilized to amplify the pol gene from plasma RNA samples obtained from the participants. Genotypic and HIV drug resistance were determined using the Stanford University HIV Drug Resistance Database. …”
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Effect of misclassification of antiretroviral treatment status on the prevalence of transmitted HIV-1 drug resistance
Published 2012-03-01“…<p>Abstract</p> <p>Background</p> <p>Estimates of the prevalence of transmitted HIV drug resistance (TDR) in a population are derived from resistance tests performed on samples from patients thought to be naïve to antiretroviral treatment (ART). …”
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The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001–2006) in Portugal
Published 2008-02-01“…This is most probably reflecting the changing drug prescription, the increasing efficiency of HAART and the improved management of HIV drug resistance. This work was presented in part at the Eighth International Congress on Drug Therapy in HIV Infection, Glasgow (UK), 12-16 November 2006 (PL5.5); and at the Fifth European HIV Drug Resistance Workshop, Cascais (Portugal), 28-30 March 2007 (Abstract 1).…”
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Longitudinal Trends in HIV-1 Subtypes and Drug Resistance in Children from Argentina over a 15-Year Period (2006-2021)
Published 2024-01-01“…Background: Human immunodeficiency virus (HIV) drug resistance is a major cause of treatment failure in children and adolescents infected with the virus. …”
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Screening for and verification of novel mutations associated with drug resistance in the HIV type 1 subtype B(') in China.
Published 2012-01-01“…OBJECTIVE: Mutations associated with HIV drug resistance have been extensively characterized at the HIV-1 polymerase domain, but more studies have verified that mutations outside of the polymerase domain also results in resistance to antiviral drugs. …”
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